Title: Cheap Flights to Santee , SC from CA $195 - Expedia.ca ![DEG7A9 Bald cypress forest in autumn at the Cuddo Unit of the Santee Refuge, SC.](https://images.trvl-media.com/place/9953/a26d5a16-8cd2-405d-94ab-122a2f63e661.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/9953/a26d5a16-8cd2-405d-94ab-122a2f63e661.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Cheap Flights to Santee , SC from CA $195 [View CA $195 flight on Thu, Oct 30, 2025](https://expedia.ca/Flights-Search?trip=oneway&leg1=from:EWR,to:CAE,departure:30/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:194.10&airProductToken=AQppCjMIwYIBEgQxNTkyGMSNASDimgEonNz7AjCQ3fsCOEJAAFgBagVCQVNJQ3IIUVZBTFlOQlYKMgjBggESBDU5OTkY4poBIIIgKOHe-wIwq9_7AjhCQAFYAWoFQkFTSUNyCFFWQUxZTkJWEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) - [Roundtrip](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only [Santee Travel Guide](https://expedia.ca/Santee.dx9953)[Hotels in Santee](https://expedia.ca/Santee-Hotels.d9953.Travel-Guide-Hotels)[Santee Car Rentals](https://expedia.ca/Car-Rentals-In-Santee.d9953.Car-Rental-Guide)[Santee Vacation Packages](https://expedia.ca/Santee.d9953.Destination-Travel-Guides) ## Popular airlines to Santee - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Santee, South Carolina, United States of America,departure:20/10/2025TANYT&leg2=from:Santee, South Carolina, United States of America,to:CMH,departure:27/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Santee, South Carolina, United States of America,departure:20/10/2025TANYT&leg2=from:Santee, South Carolina, United States of America,to:CMH,departure:27/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Santee, South Carolina, United States of America,departure:20/10/2025TANYT&leg2=from:Santee, South Carolina, United States of America,to:CMH,departure:27/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![KLM](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_KL.svg) KLM [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Santee, South Carolina, United States of America,departure:20/10/2025TANYT&leg2=from:Santee, South Carolina, United States of America,to:CMH,departure:27/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"KL"}}]) - ![Virgin Atlantic](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_VS.svg) Virgin Atlantic [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Santee, South Carolina, United States of America,departure:20/10/2025TANYT&leg2=from:Santee, South Carolina, United States of America,to:CMH,departure:27/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"VS"}}]) - ![Air France](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AF.svg) Air France [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Santee, South Carolina, United States of America,departure:20/10/2025TANYT&leg2=from:Santee, South Carolina, United States of America,to:CMH,departure:27/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AF"}}]) - ![Lufthansa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LH.svg) Lufthansa [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Santee, South Carolina, United States of America,departure:20/10/2025TANYT&leg2=from:Santee, South Carolina, United States of America,to:CMH,departure:27/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LH"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 30% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.ca/login) ## How much is the cheapest flight to Santee? Prices were available within the past 7 days and start at CA $195 for one-way flights and CA $346 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Sat, Nov 1 - Sun, Nov 2 BUF Buffalo CAE Columbia CA $346 Roundtrip found 2 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:BUF,to:CAE,departure:01/11/2025TANYT&leg2=from:CAE,to:BUF,departure:02/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:345.90&airProductToken=AQpoCjIIwYIBEgQxMjA0GIEtIOKaASiY8_sCMI_0-wI4QkAAWAFqBUJBU0lDcghRVkZIWk5CVgoyCMGCARIENTg0NRjimgEggiAo5fT7AjC59fsCOEJAAVgBagVCQVNJQ3IIUVZGSFpOQlYKaAoyCMGCARIENjA4NBiCICDimgEovIX8AjCOhvwCOEJAAFgBagVCQVNJQ3IIUVZGSFpOQlYKMgjBggESBDI0MjkY4poBIIEtKM2G_AIwtIf8AjhCQAFYAWoFQkFTSUNyCFFWRkhaTkJWEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Sat, Oct 25 - Tue, Oct 28 DTW Detroit CAE Columbia CA $347 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DTW,to:CAE,departure:25/10/2025TANYT&leg2=from:CAE,to:DTW,departure:28/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:346.30&airProductToken=AQpFCiEIxJgBEgQxNjExGOO0ASDgXCj0pPsCMOyl-wI4RUAAWAEKIAjEmAESBDMwMjYY4FwggiAoh6f7AjC-p_sCOEVAAVgBCkUKIAjEmAESBDUwNDgYgiAg4FwohMb7AjDIxvsCOEVAAFgBCiEIxJgBEgQxNjQ2GOBcIOO0ASjyxvsCMOXH-wI4RUABWAESCggBEAEYASoCREwYASIECAEQASgEMAE) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Wed, Feb 25 - Sat, Feb 28 EWR New York CAE Columbia CA $403 Roundtrip found 1 hour ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:EWR,to:CAE,departure:25/02/2026TANYT&leg2=from:CAE,to:EWR,departure:28/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:402.60&airProductToken=AQo0CjII1YIBEgQ0NDkzGMSNASCCICi-j4YDMMKQhgM4S0AAWAFqBTJfZWNvcghLRkEyQURETgpnCjEI1YIBEgQ0NDE5GIIgIIgYKN60hgMwxbWGAzhLQABYAWoFMl9lY29yCEtGQTJBREROCjII1YIBEgQxOTk3GIgYIMSNASj5tYYDMMO2hgM4S0AAWAFqBTJfZWNvcghLRkEyQUREThIKCAEQARgBKgJVQRgBIgQIARABKAIoAygEMAs) ![WestJet](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/WS.gif) Tue, Apr 28 - Wed, May 13 YYC Calgary CAE Columbia CA $669 Roundtrip found 2 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:YYC,to:CAE,departure:28/04/2026TANYT&leg2=from:CAE,to:YYC,departure:13/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:668.70&airProductToken=AQpmCiAI16YBEgQzMzAwGJgWIJgxKObHiwMwoMiLAzhMQABYAQogCNemARIEMTA2OBiYMSDgXCjjyIsDMOfKiwM4TEABWAEKIAjXpgESBDczMTUY4FwggiAoqMuLAzDky4sDOExAAVgBCkQKIAjXpgESBDgwMDkYgiAg4Fwoj_OMAzDV84wDOExAAFgBCiAI16YBEgQxNTkxGOBcIJgWKJf0jAMwtPaMAzhMQAFYARIKCAEQARgBKgJXUxgBIgQIARABKAQwAQ) ![Alaska Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AS.gif) Tue, Jan 6 - Tue, Jan 27 YVR Vancouver CAE Columbia CA $1,005 Roundtrip found 6 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:YVR,to:CAE,departure:06/01/2026TANYT&leg2=from:CAE,to:YVR,departure:27/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1004.19&airProductToken=AQqQAQovCMGmARIEMjEyMhi4jQEgkgEo9-GBAzC54oEDOFFAAFgBagJQTXIIUTdBQ1pOTjEKLQjBpgESAzM3MRiSASDvWSjp4oEDMJ3lgQM4UUABWAFqAlBNcghRN0FDWk5OMQouCMGmARIENjQ5MhjvWSCCICjK5oEDMMfngQM4R0ABWAFqAlBNcghRN0FDWk5OMQqMAQotCMGmARIENjg1NhiCICBDKOnIgwMwyMmDAzhHQABYAWoCUE1yCFE3QUNaTk4xCioIwaYBEgEzGEMgkgEoycuDAzC3zoMDOFFAAVgBagJQTXIIUTdBQ1pOTjEKLwjBpgESBDMwMDUYkgEguI0BKOnPgwMwqtCDAzhRQAFYAWoCUE1yCFE3QUNaTk4xEgoIARABGAEqAkFTGAEiBAgBEAEoAigDKAQwAQ) ## Find the cheapest month to fly from Columbus (CMH) to Columbia (CAE) ### May is typically the cheapest month to fly From CA $276 - CA $626 per traveller. Expedia.ca gives you the best tools to secure great deals on flights to Santee. Use our easy and convenient booking engine to browse nonstop flights and convenient departure points every day of the year. Search airfares from the top airlines to book your perfect flight to Santee. Whatever your travel needs, you can always rely on Expedia.ca to help you find cheap flights to Santee. Using our booking engine is simple - just type in your points of travel and preferred dates and Expedia.ca does the rest! If your travel times are flexible, you can find even better bargains by adjusting your flight dates. Browse connecting flights to increase your chances of finding even lower fares. Thanks to Expedia's Best Price Guarantee, you can book your Santee flights with full confidence knowing that you've found the best deal online. Expedia.ca makes the booking process easy and stress-free by offering support along the entire way. Our friendly staff is available 24 hours a day to provide assistance and help you book your ticket. Call us toll-free at 1-888-397-3342 to answer any questions that you may have about your trip to Santee. Looking to save even more? Get additional savings by bundling your Santee flight with a hotel and/or car rental to create a bargain travel package. Early birds can discover terrific savings by booking in advance while last minute travelers can enjoy great last minute deals. With Expedia.ca, there's no shortage of options to save even more on your Santee trip! Flights to Santee information | Destination airport | Columbia Metropolitan | | --- | --- | | Destination airport IATA code | CAE | | Destination city name | Columbia | | Roundtrip price | CA $346 | ## Need more than a Flight to Santee? Heading to Santee? Explore Santee with Expedia's Travel Guides to find the best hotels, vacation packages, car rental deals and more! [Santee Hotels](https://expedia.ca/Santee-Hotels.d9953.Travel-Guide-Hotels)[Santee Vacation Rentals](https://expedia.ca/Santee-Vacation-Rentals.d9953.Travel-Guide-VacationRentals)[Santee Car Rentals](https://expedia.ca/Car-Rentals-In-Santee.d9953.Car-Rental-Guide) ## Trending flights to Santee Prices were available within the past 7 days and start at CA $195 for one-way flights and CA $346 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Tue, Mar 3 - Tue, Mar 31 YOW Ottawa CAE Columbia CA $420 Roundtrip found 11 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:YOW,to:CAE,departure:03/03/2026TANYT&leg2=from:CAE,to:YOW,departure:31/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:419.81&airProductToken=AQptCjUI1YIBEgQzNjE5GNizASCIGCiD1IYDMPfUhgM4TkAAWAFqCEVDT0JBU0lDcghHTkEyQTBCTgo0CNWCARIENDU1ORiIGCCCICjZ14YDMLzYhgM4TkABWAFqCEVDT0JBU0lDcghHTkEyQTBCTgptCjQI1YIBEgQ1Mjg1GIIgIK4cKNyMiQMw6Y2JAzhOQABYAWoIRUNPQkFTSUNyCEdOQTJBMEJOCjUI1YIBEgQzNDAyGK4cINizASj4kIkDMOqRiQM4TkABWAFqCEVDT0JBU0lDcghHTkEyQTBCThIKCAEQARgBKgJVQRgBIgQIARABKAIoAygEMAE) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental ### Lodging - [5 Star Hotels in Manning](https://www.expedia.ca/5Star-Manning-Hotels.s50-0-d8454.Travel-Guide-Filter-Hotels) - 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[Apartments in Wilkinson Heights](https://www.expedia.ca/Wilkinson-Heights-Apartments.d553248634999270849-aaApartments.Travel-Guide-Accommodation) ### Flights - [Flights to Barnwell](https://www.expedia.ca/Cheap-Flights-To-Barnwell.d55052.Travel-Guide-Flights) - [Flights to Blythewood](https://www.expedia.ca/Cheap-Flights-To-Blythewood.d180657.Travel-Guide-Flights) - [Flights to Camden](https://www.expedia.ca/Cheap-Flights-To-Camden.d85740.Travel-Guide-Flights) - [Flights to Charleston Intl.](https://www.expedia.ca/Cheap-Flights-To-Charleston-Intl.d5457987.Travel-Guide-Flights) - [Flights to Charleston](https://www.expedia.ca/Cheap-Flights-To-Charleston.d179997.Travel-Guide-Flights) - [Flights to Coastal South Carolina](https://www.expedia.ca/Cheap-Flights-To-Coastal-South-Carolina.d6057937.Travel-Guide-Flights) - [Flights to Columbia Metropolitan](https://www.expedia.ca/Cheap-Flights-To-Columbia-Metropolitan.d4538691.Travel-Guide-Flights) - [Flights to Columbia](https://www.expedia.ca/Cheap-Flights-To-Columbia.d764.Travel-Guide-Flights) - 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[Flights to Walterboro](https://www.expedia.ca/Cheap-Flights-To-Walterboro.d9656.Travel-Guide-Flights) - [Flights to Colleton County](https://www.expedia.ca/Destinations-In-Colleton-County.d553248635976433901.Flight-Destinations) - [Flights to South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina.d242.Flight-Destinations) - [Flights from Vance](https://www.expedia.ca/lp/flights/3000456153/flights-from-vance) - [Flights from Pinewood](https://www.expedia.ca/lp/flights/553248634998786949/flights-from-pinewood) - [Flights from Harleyville](https://www.expedia.ca/lp/flights/6046883/flights-from-harleyville) ### Packages - [Visit Whetsell](https://www.expedia.ca/Whetsell.dx553248635974902828) ### Cars - [Alamo Rent A Car Rental Cars in Manning](https://www.expedia.ca/Alamo-Rent-A-Car-Car-Rentals-In-Manning.d8454-c6.Car-Rental-Guide-Suppliers) - [Car rental Manning](https://www.expedia.ca/Car-Rentals-In-Manning.d8454.Car-Rental-Guide) - [Sr Rent A Car Rental Cars in Bowman](https://www.expedia.ca/SR-Rent-A-Car-Car-Rentals-In-Bowman.d553248634998681915-c1077.Car-Rental-Guide-Suppliers) ### Vacation Rental - [Eutawville Vacation Rentals](https://www.expedia.ca/Eutawville-Vacation-Rentals.d3000455924.Travel-Guide-VacationRentals) \*Available to Expedia members.