Title: Book The Best Hotels in Santee, SC for 2025 from CA $74 - Compare prices by date | Expedia.ca [Santee Travel Guide](https://expedia.ca/Santee.dx9953)[Vacation Rentals in Santee](https://expedia.ca/Santee-Vacation-Rentals.d9953.Travel-Guide-VacationRentals)[Flights to Santee](https://expedia.ca/Cheap-Flights-To-Santee.d9953.Travel-Guide-Flights)[Santee Car Rentals](https://expedia.ca/Car-Rentals-In-Santee.d9953.Car-Rental-Guide)[Santee Vacation Packages](https://expedia.ca/Santee.d9953.Destination-Travel-Guides) ![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santee, SC from CA $74 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santee Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2025-10-25&d1=2025-10-25&endDate=2025-10-27&d2=2025-10-27&amenities=PETS) Pool [](https://www.expedia.ca/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2025-10-25&d1=2025-10-25&endDate=2025-10-27&d2=2025-10-27&amenities=POOL) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2025-10-25&d1=2025-10-25&endDate=2025-10-27&d2=2025-10-27&travelerType=family_friendly) ## Check prices for these dates Tonight [Oct 11 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2025-10-11&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 12 - Oct 13](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2025-10-12&endDate=2025-10-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 290 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Lobby](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/8f64bf7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing)](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/828f10f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/cce2b53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Santee Santee 9.2/10 Wonderful (560) "Great stay" CA $151 CA $168 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/2824d996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/ddfa8a2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/6e319d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee Santee 8.0/10 Very good (1000) "Great place to stay." CA $148 CA $164 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/756b4cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c5237c95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee Santee 8.0/10 Very good (1356) "Good overall stay." CA $112 CA $124 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/170f28f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/67341601.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee Santee 9.8/10 Exceptional (1004) "Great stay for a quick weekend getaway!" CA $175 CA $194 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/ebe97e99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/28717b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/eeb5fa18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Santee Santee 7.0/10 Good (662) "Good location " CA $87 CA $96 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5897ba97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/65520f0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/e757bdfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Santee-I-95 Santee 9.6/10 Exceptional (1002) "Staff was very friendly and accommodating. " CA $171 CA $189 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/e27bc6de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/8a3aa504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/442e4efc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santee by IHG Santee 8.2/10 Very good (953) "Friendly and helpful staff. Overall a very good stay." CA $156 CA $173 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/3861a053.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/10951979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/ccd798ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/1295e8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Santee 6.0/10 (443) "Entire place was filthy I did not even check in " CA $88 CA $106 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/725815f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ab86ecd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/4aad61ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Santee Inn Santee 8.8/10 Excellent (1003) "The staff was very friendly and welcoming. The enviroment was very calm and peaceful." CA $190 CA $211 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/41ed20e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/61b41f5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/740d6803.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/23463ec8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Santee I-95 Santee 6.2/10 (537) "The grounds and property were clean and you could tell they take pride in what they're offering." CA $100 CA $111 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/4686cd8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/8136c59d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/e9087580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/b105c391.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Santee Santee 6.6/10 (629) "Despite offering breakfast, it was lackluster " CA $98 CA $109 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2fd60881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/77599f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/aa634b56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/315e8dc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Santee Santee 6.8/10 (435) "The nicest bathroom on our 12 day trip" CA $105 CA $117 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/1f93ecf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/6c8567ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/3b5b7fa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/60673add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Santee 6.4/10 (309) "Check in was easy." CA $83 CA $92 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Orangeburg-Hotels-Econo-Lodge.h905358.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/57735ca3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/a4197341.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness studio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/7b01c436.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Orangeburg Orangeburg 9.2/10 Wonderful (1007) "Great little hotel. Perfect for a short stay. " CA $148 CA $164 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/8acfa265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/321b05a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2556x0y4-5cb4ef80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3837h2557x3y3-7acc8337.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Orangeburg Orangeburg 7.8/10 Good (1005) "Very close to highway, I come to the area 3 times a year, and this is the nicest place yet" CA $122 CA $136 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/377ba79f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/cc6b1fba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/208c4454.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/5fe5c871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Orangeburg 8.0/10 Very good (513) "EVERYTHING WAS CLEAN AND NICE" CA $137 CA $152 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/2eadf4bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/e85d0e8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/e088653f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/a66aad1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham St George St. George 7.6/10 Good (1004) "Very pleasant stay " CA $93 CA $103 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/54902f8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two queen beds non smoking](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/e1b5940b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/f127cd7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/ab9e6646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Manning Manning 8.4/10 Very good (980) "Clean Easy room access, spacious couch and comfortable king bed combination room " CA $149 CA $165 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Sumter-Hotels-Hampton-Inn-Manning.h1418684.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/e6b95688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/fb97cba6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/e307c591.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/b76457c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western Manning Manning 8.6/10 Excellent (1001) "People were fantasticly friendly. " CA $147 CA $163 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Sumter-Hotels-SureStay-Hotel-By-Best-Western-Manning.h569301.Hotel-Information) ![Standard Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/110000/100500/100411/f6e62ff1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/110000/100500/100411/f848d3f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/110000/100500/100411/500cab17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/110000/100500/100411/09bb2a32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Orangeburg Orangeburg 5.6/10 (698) "Simple hotel " CA $67 CA $74 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Orangeburg-Hotels-Days-Inn-By-Wyndham-Orangeburg.h100411.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-25&endDate=2025-10-26®ionId=9953&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels.d9953.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels.d9953.Travel-Guide-Hotels) ## Learn more about Santee Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campgrounds. [See all hotels in Santee](https://www.expedia.ca/Hotel-Search?startDate=2025-10-25&endDate=2025-10-26&adults=2®ionId=9953) ![](https://mediaim.expedia.com/destination/1/271db9a9db85f6f3488271b71d2f238f.jpg?impolicy=fcrop&w=900&h=280&p=1&q=high) ### Stay near popular Santee attractions Santee, South Carolina is an ideal destination for outdoor enthusiasts and those seeking a romantic getaway. Visitors can explore stunning natural attractions such as Santee State Park, along with beautiful lakes and islands. This charming locale offers a blend of beach activities and cultural experiences, catering to various interests for a memorable vacation. [](https://expedia.ca/Santee-State-Park-Hotels.0-l6140632-0.Travel-Guide-Filter-Hotels) #### Santee State Park Santee State Park offers breathtaking scenery, thrilling outdoor adventures, and a vibrant atmosphere, making it a perfect destination for nature enthusiasts and those seeking relaxation. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6140632) [](https://expedia.ca/Santee-Cooper-Country-Club-Hotels.0-l553248621532654899-0.Travel-Guide-Filter-Hotels) #### Santee Cooper Country Club Enjoy a round of golf at Santee Cooper Country Club, surrounded by lush landscapes, followed by relaxing outdoor activities like hiking and picnicking in nature's embrace. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532654899) [](https://expedia.ca/Santee-National-Golf-Club-Hotels.0-l553248621532654897-0.Travel-Guide-Filter-Hotels) #### Santee National Golf Club Santee National Golf Club offers serene outdoor vibes with lush landscapes, perfect for rejuvenating walks, yoga sessions, and golf, providing a tranquil retreat for wellness enthusiasts. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532654897) ## More cheap stays in Santee ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Santee 263 Britain St. and 273 Britain St., Santee, SC CA $151 CA $168 total Nov 3 - Nov 4 includes taxes & fees 9/10 Wonderful! (556 reviews) [](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Santee 249 Britain Street, Santee, SC CA $112 CA $124 total Oct 12 - Oct 13 includes taxes & fees 7.8/10 Good! (1,351 reviews) [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Tru by Hilton Orangeburg](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru by Hilton Orangeburg 739 Citadel Road, Orangeburg, SC CA $148 CA $164 total Oct 27 - Oct 28 includes taxes & fees 9/10 Wonderful! (1,004 reviews) [](https://expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Spark by Hilton Orangeburg](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/8acfa265_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Spark by Hilton Orangeburg 731 Citadel Road, Orangeburg, SC CA $122 CA $136 total Oct 19 - Oct 20 includes taxes & fees 7.6/10 Good! (1,004 reviews) [](https://expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn & Suites by Marriott Santee 9074 Old Number Six Hwy, Santee, SC CA $175 CA $194 total Nov 11 - Nov 12 includes taxes & fees 9.8/10 Exceptional! (1,004 reviews) [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Days Inn by Wyndham St George](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/2eadf4bd_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham St George 139 Motel Dr, St. George, SC CA $93 CA $103 total Nov 9 - Nov 10 includes taxes & fees 7.4/10 Good! (1,003 reviews) [](https://expedia.ca/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) ## Hotels in Santee with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/bfd80ad8_w.jpg) 4 Star Hotels 1 properties [](https://expedia.ca/4Star-Santee-Hotels.s40-0-d9953.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1_w.jpg) 3 Star Hotels 9 properties [](https://expedia.ca/3Star-Santee-Hotels.s30-0-d9953.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_w.jpg) 2 Star Hotels 69 properties [](https://expedia.ca/2Star-Santee-Hotels.s20-0-d9953.Travel-Guide-Filter-Hotels) ## Find out more about Santee ### Top reasons to visit Santee - **Outdoor Adventures:** Santee offers stunning hiking trails and recreational areas perfect for outdoor enthusiasts. - **Santee State Park:** Explore beautiful lakes and nearby islands for a serene nature experience. - **Golfing:** Enjoy a round of golf at local courses amidst picturesque landscapes. - **Shopping:** Indulge in retail therapy at the nearby outlet mall for a well-rounded vacation. - **Accommodations for All:** A variety of hotels cater to diverse needs, ensuring a comfortable stay. ### Find great hotels in and around Santee Discover the charm of Santee, South Carolina, where a variety of hotels and motels cater to every traveller's needs. Whether you're seeking pet-friendly accommodations, a welcoming atmosphere for LGBTQIA guests, or business-focused amenities, Santee has you covered. With options ranging from the best hotels to top-rated choices, your ideal stay awaits in this picturesque destination. - **[Baymont by Wyndham Santee:](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information)** Experience the charm of Santee at Baymont by Wyndham, a welcoming hotel that caters to both business and pet-friendly travellers. This property offers a comfortable stay with amenities designed for those on the go, including business facilities tailored for professional needs. With a flexible pet policy, guests can travel with their furry companions, ensuring that no family member is left behind. Enjoy the convenience of modern amenities while feeling right at home in this inviting atmosphere. - **[Fairfield Inn by Marriott Orangeburg:](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information)** Just a short drive from Santee, the Fairfield Inn by Marriott Orangeburg stands out as an inclusive and business-friendly hotel. Known for its warm hospitality and LGBTQIA welcoming environment, this property is perfect for diverse travellers. Guests can take advantage of the 24-hour business centre, making it easy to stay productive during their visit. The hotel’s attention to creating an inclusive atmosphere is complemented by comfortable accommodations, ensuring a pleasant and stress-free stay. - **[Best Western Plus Santee Inn:](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information)** Nestled in the heart of Santee, the Best Western Plus Santee Inn combines business amenities with a pet-friendly approach. This hotel features a comprehensive business centre, conference space, and meeting rooms, making it ideal for both corporate gatherings and leisure travellers alike. With a welcoming environment for pets, guests can enjoy the added benefit of a dog exercise area, allowing their pets to stretch their legs. The blend of professional facilities and home-like comfort ensures a memorable stay for all. ### Where to stay near Santee Santee, South Carolina, offers a perfect blend of outdoor adventures and serene getaways for Canadian travellers. Nestled among scenic views and tranquil waters, this charming city is ideal for romantic escapes or family-friendly excursions. Nearby regions boast a friendly atmosphere and budget-friendly options, ensuring a memorable experience for all. Whether you seek a quieter retreat or vibrant outdoor activities, Santee has something for everyone to enjoy. - **[Summerton:](https://www.expedia.ca/Summerton-Hotels.d163488.Travel-Guide-Hotels)** Located 17.7km from Santee, Summerton offers a charming small-town atmosphere with a focus on outdoor activities and natural beauty. Visitors are drawn to its scenic landscapes, making it an ideal destination for a romantic getaway. The peak travel seasons in March to April and July enhance its appeal, as travellers can enjoy recreational areas and golf courses. Nearby attractions include picturesque lakes and the stunning national state park, providing ample opportunities for exploration and relaxation in nature. - **[Vance:](https://www.expedia.ca/Vance-Hotels.d3000456153.Travel-Guide-Hotels)** Situated just 8.0km from Santee, Vance is a quaint city that experiences highly seasonal visitor patterns, particularly in March to April and July. Known for its outdoor offerings and scenic vistas, Vance is perfect for couples seeking a romantic escape. With access to recreational areas and golf courses, guests can enjoy leisurely outdoor activities. Local landmarks such as beautiful lakes, the national state park, and nearby islands make Vance a delightful stop for those looking to immerse themselves in South Carolina's natural beauty. - **[Elloree:](https://www.expedia.ca/Elloree-Hotels.d3000455923.Travel-Guide-Hotels)** Only 9.7km away from Santee, Elloree is a vibrant city that attracts visitors year-round, with peak periods in March, July, and September. This charming location is ideal for outdoor enthusiasts and couples seeking scenic experiences. Guests can enjoy a variety of activities, including access to golf courses and recreational spaces. Notable nearby attractions include tranquil lakes and the captivating national park, making Elloree a fantastic spot for nature lovers to unwind and explore the great outdoors. ### Things to do in and around Santee Santee, South Carolina, is perfect for outdoor enthusiasts and couples seeking a romantic getaway. Enjoy activities like hiking scenic trails, playing a round of golf at one of the local golf courses, or exploring the recreational areas. After a day of adventure, unwind with the nightlife options available or indulge in some shopping at the nearby outlet mall, ensuring a well-rounded vacation experience. **Shopping** In Santee, check out local gem [Bee City](https://www.expedia.ca/Bee-City-Hotels.0-l553248621532654894-0.Travel-Guide-Filter-Hotels) for unique gifts. If you're up for a drive, visit Pocalla Crossing Shopping Center, located 43.5km away, featuring a variety of shops and a family-friendly atmosphere, perfect for souvenirs and local finds. **Recreation** [Santee Cooper Country Club](https://www.expedia.ca/Santee-Cooper-Country-Club-Hotels.0-l553248621532654899-0.Travel-Guide-Filter-Hotels) offers a scenic golfing experience amid lush landscapes, perfect for sports enthusiasts. [Santee National Wildlife Refuge](https://www.expedia.ca/Santee-National-Wildlife-Refuge-Hotels.0-l553248621532654901-0.Travel-Guide-Filter-Hotels) provides a serene retreat for relaxation and nature appreciation, while [Patriots Sports Plex](https://www.expedia.ca/Patriots-Sports-Plex-Hotels.0-l553248623546509706-0.Travel-Guide-Filter-Hotels) features various recreational activities to rejuvenate your spirit and promote wellness. **Adventure** Santee State Park offers thrilling opportunities for hiking, fishing, and canoeing amidst beautiful landscapes. Explore the scenic trails or cast a line into the tranquil waters of Lake Marion, where you can enjoy peaceful surroundings and spot local wildlife in their natural habitat. **Nightlife** Santee offers a laid-back nightlife scene, perfect for unwinding after a day of exploration. Enjoy live music at the local pubs or relax by the lake with friends. The nearby restaurants offer cozy atmospheres for evening dining, making it an ideal spot for a casual night out. *\*Distances are measured in a straight line; actual driving distances may vary depending on the route.* ### Booking tips and Expedia advantages for Santee Santee, South Carolina, is a budget-friendly destination with free entry to attractions like Taw Caw Creek. To save on accommodations, consider visiting between December and February, with Mondays typically offering the lowest rates. For getting around, options include cars, buses, and bikes. Utilize Expedia to find eco-certified hotels and combine your hotel, flights, and activities for additional savings. Remember, Saturdays are the priciest days to stay, so planning around this can help you save more during your visit. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Santee are December to February, where the prices are slightly lower. This is in comparison to April to May and October, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Santee is Monday. The most expensive day to stay in Santee is Saturday. - **Find cheap hotels on Expedia:** Utilize Expedia's search tool to refine your preferences, such as your budget, desired location, and preferred type of accommodation. For instance, selecting the Eco-certified option will showcase sustainable and environmentally friendly hotels currently available. To find the best prices and offers, sort the price filter from lowest to highest. - **Consider bundling your trip:** You can save money by combining your hotel stay in Santee with your flights and activities through an Expedia package. ### Best time to go to Santee The best time to visit Santee is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --- | --- | --- | --- | --- | --- | | January | 47.3°F (8.5°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | February | 51.4°F (10.8°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | March | 56.8°F (13.8°C) | Light Rain | Mostly Sunny | Slightly High | Average | | April | 64.4°F (18.0°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | May | 72.0°F (22.2°C) | Light Rain | Mostly Sunny | Average | Slightly High | | June | 78.6°F (25.9°C) | Light Rain | Mostly Sunny | Average | Average | | July | 81.5°F (27.5°C) | Light Rain | Mostly Sunny | Slightly High | Average | | August | 79.9°F (26.6°C) | Light Rain | Mostly Sunny | Average | Average | | September | 75.4°F (24.1°C) | Light Rain | Mostly Sunny | Average | Average | | October | 66.4°F (19.1°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly High | | November | 56.1°F (13.4°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | December | 51.3°F (10.7°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | ### The nearest major airports for your trip to Santee For your visit to Santee, South Carolina, you can conveniently fly into two major airports. Charleston International Airport ([CHS](https://www.expedia.ca/Charleston-Intl-Airport-Hotels.0-aCHS-0.Travel-Guide-Filter-Hotels)) is situated 78.9km away, with excellent hotel options like [The Charleston Place](https://www.expedia.ca/Charleston-Hotels-Charleston-Place.h28504.Hotel-Information), [The Dewberry Charleston](https://www.expedia.ca/Charleston-Hotels-The-Dewberry-Charleston.h12880056.Hotel-Information), and [Hotel Bennett](https://www.expedia.ca/Charleston-Hotels-Hotel-Bennett.h22649862.Hotel-Information), all 14.5km from the airport and offering transfers and shuttles. Alternatively, Columbia Metropolitan Airport ([CAE](https://www.expedia.ca/Columbia-Metropolitan-Airport-Hotels.0-aCAE-0.Travel-Guide-Filter-Hotels)) is also 78.9km from Santee, with hotels such as [Graduate by Hilton Columbia SC](https://www.expedia.ca/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information), [Doubletree by Hilton Columbia](https://www.expedia.ca/Columbia-Hotels-Doubletree-By-Hilton-Columbia.h1090.Hotel-Information), and [Marriott Columbia](https://www.expedia.ca/Columbia-Hotels-Marriott-Columbia.h17353.Hotel-Information) located 6 to 11.3km away, providing easy access to the airport. Both airports ensure a smooth travel experience to your destination. ## Recent reviews of Santee hotels ![Fairfield Inn & Suites by Marriott Santee](//images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg) ### Fairfield Inn & Suites by Marriott Santee 5/5 Excellent "place was beautiful, workers were nice and courteous and helpful" A verified traveller stayed at Fairfield Inn & Suites by Marriott Santee Posted 3 days ago [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Holiday Inn Santee by IHG](//images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1_y.jpg) ### Holiday Inn Santee by IHG 5/5 Excellent "Acting GM was very friendly Happy hour was nice" A verified traveller stayed at Holiday Inn Santee by IHG Posted 3 days ago [](https://expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Tru By Hilton Santee](//images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg) ### Tru By Hilton Santee 5/5 Excellent "Very nice facility " A verified traveller stayed at Tru By Hilton Santee Posted 5 days ago [](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Baymont by Wyndham Santee](//images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg) ### Baymont by Wyndham Santee 5/5 Excellent "Great place to stop on our way to Florida. Places to shop and dine. Hotel is nice and good breakfast. " A verified traveller stayed at Baymont by Wyndham Santee Posted 6 days ago [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Travelodge by Wyndham Santee](//images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd_y.jpg) ### Travelodge by Wyndham Santee 5/5 Excellent "The counter tops and appliances needed cleaning, they were greasy. Otherwise the room was okay." A verified traveller stayed at Travelodge by Wyndham Santee Posted 6 days ago [](https://expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!](//images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/dc99579a_y.jpg) ### Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95! 5/5 Excellent "Great house, very modern interior. Very clean. Close to town. We’ll definitely book the house on our fishing trip. " A verified traveller stayed at Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95! Posted 11 days ago [](https://expedia.ca/Santee-Hotels-This-House-Is-A-3-Bedroom.h91788460.Hotel-Information) ![Hampton Inn Santee-I-95](//images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg) ### Hampton Inn Santee-I-95 5/5 Excellent "We had a nice and courteous and friendly. Bed was comfortable " A verified traveller stayed at Hampton Inn Santee-I-95 Posted 12 days ago [](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Quality Inn & Suites](//images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/3861a053_y.jpg) ### Quality Inn & Suites 5/5 Excellent "Great place. Excellent people. Great service" A verified traveller stayed at Quality Inn & Suites Posted 1 month ago [](https://expedia.ca/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Ramada by Wyndham Santee I-95](//images.trvl-media.com/lodging/1000000/20000/11700/11623/41ed20e6_y.jpg) ### Ramada by Wyndham Santee I-95 5/5 Excellent "The grounds and property were clean and you could tell they take pride in what they're offering." A verified traveller stayed at Ramada by Wyndham Santee I-95 Posted 1 month ago [](https://expedia.ca/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information) ## Frequently asked questions ### What are the best hotels in Santee that travellers recommend? > [Holiday Inn Santee by IHG](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) stands out as a top choice for travellers, earning a review score of 8.2. This hotel combines comfort with convenience, making it a great option for groups and solo travellers. With spacious rooms and attentive service, guests feel right at home. The hotel features a ballroom for events and room service, ensuring that all your needs are met without hassle. ### What are the best family hotels in Santee? > [Holiday Inn Santee by IHG](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) stands out as an excellent family-friendly option in Santee, South Carolina, with an excellent traveller review rating of 8.2. This hotel offers spacious rooms that include cribs and connecting rooms, making it easy for families to stay close together while enjoying their own space. Find more [child-friendly accommodations in Santee](https://www.expedia.ca/Santee-Hotels-Family-Hotel.0-0-d9953-tFamilyHotel.Travel-Guide-Filter-Hotels). ### What are the top pet-friendly hotels in Santee? > [Holiday Inn Santee by IHG](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) is a fantastic option for pet-friendly travellers seeking a blend of comfort and convenience. This hotel welcomes small pets, ensuring that your furry friends can join in on the adventure. Guests appreciate the inviting indoor pool, great for a refreshing dip after a day of exploring, and the nearby golf course offers a delightful opportunity for those looking to tee off amidst beautiful scenery. See more [pet-friendly hotels in Santee](https://www.expedia.ca/santee-hotels-pet-friendly-hotel.0-0-d9953-tpetfriendlyhotel.travel-guide-filter-hotels). ### What are the best budget hotels in Santee? > For budget-conscious travellers seeking comfort and convenience in Santee, the [Fairfield Inn & Suites by Marriott Santee](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) stands out with an impressive guest review rating of 9.8. This hotel offers a delightful array of amenities, including complimentary breakfast options and free WiFi, ensuring a straightforward stay. Families will appreciate the outdoor pool, accessible fitness centre, and the availability of cribs and highchairs, making it a welcoming environment for kids. > > > > Another excellent choice is the [Hampton Inn Santee-I-95](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information), rated 9.6 by guests. This property also features an outdoor seasonal pool and offers free breakfast, creating the great start to a day of adventure. With spacious rooms equipped with cribs and rollaway beds, families can comfortably settle in without worry. > > > > Couples looking for a cozy retreat may also enjoy the [Best Western Plus Santee Inn](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information), which, while slightly lower on the review scale at 8.8, boasts a charming atmosphere with an indoor hot tub and kitchen facilities for added convenience. > > > > Each of these hotels provides a friendly and accommodating experience, allowing travellers to focus on their adventures while enjoying quality service without stretching their budget. View all [budget hotels in Santee](https://www.expedia.ca/santee-hotels-cheap-hotels.0-0-d9953-tcheaphotels.travel-guide-filter-hotels). ### When is the best time to go to Santee? > The most popular time to visit Santee is April, when the weather begins to warm up, creating a delightful atmosphere for outdoor adventures. Temperatures typically range from 15 to 24 Celsius, making it superb for enjoying the beautiful parks and scenic landscapes that the area has to offer. > > > > Santee experiences its peak season from March to May, attracting a steady flow of tourists eager to partake in various activities. The mild climate during this period is particularly inviting for hiking, biking, and even fishing in the nearby lakes. With the lush greenery in full bloom, it's an excellent time to explore the natural beauty surrounding the area. > > > > For families and couples alike, April is an especially appealing month. The community often hosts local events and festivals that provide a wonderful opportunity to engage with residents and immerse yourself in the local culture. You can enjoy picnics in the park, stroll along the trails, or take part in outdoor sports, all while basking in the pleasant sun. > > > > If you're looking for a more budget-friendly option, consider visiting in November. While the weather may be cooler, it offers a unique perspective on Santee's charm, and you can often find lower accommodation rates during this time. ### Can I cancel my hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Santee hotel for you. ### How can I save on a Santee hotel booking with Expedia? > With Expedia, you'll unlock our lowest prices by becoming a member. It's free and easy to join, and you can even access member perks too. Just remember to sign in to get our best prices on Santee hotels. Another way to save is by booking your hotel and flights together on Expedia, where bundling can lead to significant savings. ### How much is the nightly rate at a Santee hotel? > Prices for hotels in Santee often vary, but you can find a great deal from CA $74 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. 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