Find hotels in Santee, SC from CA $77

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Top 10 Santee hotels and places to stay

Cozy home. 15 minutes from the lake and 30 minutes from the beach!
Fridge, oven, stovetop, coffee/tea maker
Cozy home. 15 minutes from the lake and 30 minutes from the beach!
10.0 out of 10, Exceptional, (2)
"Awesome host and place"
The price is CA $144
CA $317 total
includes taxes & fees
May 21 - May 22
Cozy home. 15 minutes from the lake and 30 minutes from the beach!
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Aerial view
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
10.0 out of 10, Exceptional, (16)
"We just stayed for a night to recharge and hit the road again. It was the perfect place to rest for our family of 4 plus 2 dogs."
The price is CA $183
CA $500 total
includes taxes & fees
May 20 - May 21
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Waterfront 3 Bedroom / 3 Bath Condo w/ Boat Slip Available
View from property
Waterfront 3 Bedroom / 3 Bath Condo w/ Boat Slip Available
10.0 out of 10, Exceptional, (32)
"We are three couples over the age of 60 and just loved having our own bathrooms. The pictures of the condo do not do it justice! Everything was just perfect. We loved sitting on the balcony overlooking the lake, especially seeing all the wildlife! We will definitely be back!"
Waterfront 3 Bedroom / 3 Bath Condo w/ Boat Slip Available
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Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
Property grounds
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
10.0 out of 10, Exceptional, (11)
"Would book again. Enjoyed our stay."
The price is CA $116
CA $235 total
includes taxes & fees
May 14 - May 15
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
New Lakefront Deck Home with Dock, Views
Beach nearby
New Lakefront Deck Home with Dock, Views
10.0 out of 10, Exceptional, (4)
"We really enjoyed it I would stay here again"
New Lakefront Deck Home with Dock, Views
Fairfield Inn & Suites by Marriott Santee
Property amenity
Fairfield Inn & Suites by Marriott Santee
2.5 star property
9.8 out of 10, Exceptional, (988)
"This hotel was an excellent choice for us after a long day on I95. The room was perfect and included a microwave and mini fridge. The bed was super comfortable and everything was very clean. The tv remote was clean and in plastic and there was an antiseptic cleaning cloth next to the bed if needed. The breakfast area also was very clean and tidy and the eggs were really good. Roz did an excellent job keeping the food refilled and nicely presented. I would definitely stay here again."
The price is CA $200
CA $222 total
includes taxes & fees
May 28 - May 29
Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95
Exterior
Hampton Inn Santee-I-95
2.5 star property
9.6 out of 10, Exceptional, (1004)
"Have stayed here several times "
The price is CA $173
CA $192 total
includes taxes & fees
Jun 2 - Jun 3
Hampton Inn Santee-I-95
Wyndham Vacation Resorts Lake Marion
Outdoor pool
Wyndham Vacation Resorts Lake Marion
4.0 star property
9.4 out of 10, Exceptional, (15)
"I enjoy my stay, customer service was exceptional. Will book again. "
Wyndham Vacation Resorts Lake Marion
Relax by Lake Marion - A lake home with you in mind.
Property grounds
Relax by Lake Marion - A lake home with you in mind.
9.4 out of 10, Exceptional, (59)
"Wonderful property for a fishing trip. Plenty of room for our three boat trailers including a covered car port that fit two of our boats at a time!"
Relax by Lake Marion - A lake home with you in mind.
Executive 2 BR/2 BA Lakefront Corner Suite Condo
Outdoor pool
Executive 2 BR/2 BA Lakefront Corner Suite Condo
9.2 out of 10, Wonderful, (20)
"In town for Birdfest weekend and really enjoyed our stay in the condo and area!"
Executive 2 BR/2 BA Lakefront Corner Suite Condo
Tru By Hilton Santee
Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing)
Tru By Hilton Santee
2.5 star property
9.0 out of 10, Wonderful, (107)
"New"
The price is CA $161
CA $179 total
includes taxes & fees
May 19 - May 20
Tru By Hilton Santee
Lakefront condo with boat slip available. 3 br, 3 ba
Lake
Lakefront condo with boat slip available. 3 br, 3 ba
9.0 out of 10, Wonderful, (9)
"2 TVs in the living room: one didn't work and one only got a few channels. Need to have soft, fluffy towels and a sheet of guidelines that tell what to do when checking out. Strip beds? etc."
Lakefront condo with boat slip available. 3 br, 3 ba
Best Western Plus Santee Inn
Exterior
Best Western Plus Santee Inn
2.5 star property
8.6 out of 10, Excellent, (1002)
"Overall, a nice motel. Not the Ritz-Carlton but clean and quiet."
The price is CA $180
CA $200 total
includes taxes & fees
May 26 - May 27
Best Western Plus Santee Inn
Lake Life on Lake Marion/Santee SC
Beach
Lake Life on Lake Marion/Santee SC
8.6 out of 10, Excellent, (7)
"Our reservations were canceled after we had received confirmation notice and instructions on how to enter the property. We were sent a welcome notice from the owner, but later told that the renters in the property wanted to extend their stay, so we were left out in the cold. We ended up having to rent motel rooms while waiting for our credit card to be released after we had been charged for the stay. We ended up in motel rooms for 12 nights instead of a house we had reserved."
Lake Life on Lake Marion/Santee SC
Holiday Inn Santee, an IHG Hotel
Exterior
Holiday Inn Santee, an IHG Hotel
3.0 star property
8.2 out of 10, Very good, (738)
" Great "
The price is CA $217
CA $241 total
includes taxes & fees
Jun 3 - Jun 4
Holiday Inn Santee, an IHG Hotel
Comfort Inn & Suites Santee
Lobby
Comfort Inn & Suites Santee
2.5 star property
8.0 out of 10, Very good, (836)
"Ok"
The price is CA $178
CA $198 total
includes taxes & fees
May 28 - May 29
Comfort Inn & Suites Santee
Baymont by Wyndham Santee
Room, 2 Queen Beds, Non Smoking
Baymont by Wyndham Santee
2.5 star property
7.8 out of 10, Good, (1327)
"Clean place, good price for overnight stay and easy access to dining and freeway."
The price is CA $103
CA $114 total
includes taxes & fees
Jun 4 - Jun 5
Baymont by Wyndham Santee
Red Roof Inn St George, SC
Lobby lounge
Red Roof Inn St George, SC
2.5 star property
7.8 out of 10, Good, (490)
"Had to change rooms as bedspreads and pillowcases had stains on them. 2nd room was not clean in the bathroom. Floor was dirty."
The price is CA $96
CA $106 total
includes taxes & fees
May 19 - May 20
Red Roof Inn St George, SC
Two Palms Lakehouse in Santee Just minutes from I95
Property grounds
Two Palms Lakehouse in Santee Just minutes from I95
7.6 out of 10, Good, (8)
"Great place for a couple days. We took advantage of the lake. Fishing was great for the grandchildren. I highly recommend this place if you enjoy being by the lake. Thank you."
Two Palms Lakehouse in Santee Just minutes from I95
Days Inn by Wyndham St George
Premium bedding, desk, laptop workspace, iron/ironing board
Days Inn by Wyndham St George
2.5 star property
7.2 out of 10, Good, (1005)
"Great place for the price. "
The price is CA $77
CA $85 total
includes taxes & fees
May 19 - May 20
Days Inn by Wyndham St George
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Where is the best place for a stay in Santee?

Fairfield Inn & Suites by Marriott Santee is a favorite property for Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on traveler reviews include Hampton Inn Santee-I-95 and Tru By Hilton Santee. See all available top hotels, or vacation rentals in Santee.

What are some of the best vacation rentals in Santee?

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable: Visitors like this Santee vacation home rental. It is located on the beach and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a garden and a selection of games. See all vacation rentals in Santee.

If I need to cancel my hotel reservation in Santee, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.

Where can I learn more about changing or cancelling my trip to Santee?

For more information about updating your trip to Santee or cancelling it, click here.

What's the best budget-friendly hotel in Santee?

Based on reviews, Baymont by Wyndham Santee is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Santee.

What's the best hotel for a family vacation in Santee?

Comfort Inn & Suites Santee is a hotel with free parking and free buffet breakfast, and it's a top choice on Expedia for families. Fairfield Inn & Suites by Marriott Santee is another choice for your family trip. Find more child-friendly accommodations in Santee.

What is the top LGBTQ-friendly accommodation in Santee?

Fairfield Inn & Suites by Marriott Santee is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Santee-I-95 and Holiday Inn Santee, an IHG Hotel are other good options for your stay. See all available hotels listed as LGBTQ-friendly in Santee.

What's the best pet-friendly accommodation in Santee?

Baymont by Wyndham Santee is a top hotel for people traveling with their pets, and offers concierge services and free WiFi for its human guests. Other good choices for you and your pet's trip include Quality Inn & Suites and Tru By Hilton Santee. See more pet-friendly hotel accommodations in Santee.

Where is the best place to stay near Santee State Park?

Baymont by Wyndham Santee is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 3 mi (4.8 km) from Santee State Park. Other good choices within 5 miles include Best Western Plus Santee Inn and Holiday Inn Santee, an IHG Hotel.

What about the best place to stay close to Santee Outlets?

One of the top choices for your stay is Baymont by Wyndham Santee, located a short 0.4 mi (0.6 km) from Santee Outlets, and this hotel offers free breakfast and free parking. Best Western Plus Santee Inn and Fairfield Inn & Suites by Marriott Santee are two other good choices in the immediate area.

What's the best golf hotel in Santee?

Holiday Inn Santee, an IHG Hotel is a top hotel that has an adjacent golf course and features free WiFi. Another good choice is Super 8 by Wyndham Santee if you'd like to be close to a golf course while in town. Visit Santee Cooper Country Club or Santee National Golf Club to perfect your golf swing. See more golf hotels in Santee.

What are some accommodations with pools in Santee?

Comfort Inn & Suites Santee is a top hotel with a seasonal outdoor pool, free buffet breakfast, and free WiFi. A couple of other options that offer an onsite pool include Fairfield Inn & Suites by Marriott Santee and Hampton Inn Santee-I-95. View all hotels with pools in Santee.

What is the best spa hotel in Santee?

Fairfield Inn & Suites by Marriott Santee is a top spa hotel featuring an outdoor pool and a 24-hour fitness center. See all spa hotels in Santee.

What's the best place to stay near Columbia Metropolitan Airport (CAE)?

Country Inn & Suites by Radisson, Columbia Airport, SC is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 1.7 mi (2.8 km) from Columbia Metropolitan Airport. Other places to stay close to the airport are Sleep Inn Airport and Red Roof Inn Columbia, SC Airport.

What is staying in Santee like?

Families will find kid-friendly activities in Santee, and visitors give high marks for the top-notch restaurants. This welcoming city also attracts tourists with its golf courses and coffeehouses. In Santee, there are 56 hotels and other accommodations to choose from. Find out more about Santee.

What is there to see in Santee?

The picturesque setting of Santee State Park and Lake Marion exemplify the area's natural beauty. A couple of additional sights to add to your agenda are Santee Cooper Country Club and Santee Outlets. Check out what more to see and do in Expedia's Santee guide.

What's the seasonal weather like in Santee?

The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.