An aerial view of a coastal landscape with a dam, farmland, and dense forests.

Find Family Hotels in Santee, SC from CA $90

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Check availability on Santee Family Hotels

Tonight
Aug 31 - Sep 1
Tomorrow
Sep 1 - Sep 2
This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Our top choices for Santee family-friendly hotels

1. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee
  • A family escape that offers vibrant pool days, premium entertainment, and free breakfast just minutes from Santee State Park.
CA $180
CA $200 total
includes taxes & fees
Sep 15 - Sep 16
Fairfield Inn & Suites by Marriott Santee

2. Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
  • Family vacation paradise with an outdoor pool, fitness centre, and quiet, pet-friendly atmosphere for your whole family.
CA $154
CA $171 total
includes taxes & fees
Sep 6 - Sep 7
Best Western Plus Santee Inn

3. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
  • Family-friendly escape at Santee with seasonal outdoor pool, free breakfast, and steps from the state park.
CA $141
CA $156 total
includes taxes & fees
Sep 20 - Sep 21
Comfort Inn & Suites Santee

4. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
Santee
CA $89
CA $99 total
includes taxes & fees
Sep 14 - Sep 15
Travelodge by Wyndham Santee

5. Econo Lodge Santee

Econo Lodge Santee
Santee
CA $85
CA $94 total
includes taxes & fees
Sep 27 - Sep 28
Econo Lodge Santee

6. Peach Tree Inn

Peach Tree Inn
St. George
CA $95
CA $103 total
includes taxes & fees
Oct 1 - Oct 2
Peach Tree Inn

7. Red Roof Inn Orangeburg

Red Roof Inn Orangeburg
Orangeburg
CA $81
CA $90 total
includes taxes & fees
Sep 6 - Sep 7
Red Roof Inn Orangeburg

8. Sleep Inn Orangeburg

Sleep Inn Orangeburg
Orangeburg
CA $137
CA $152 total
includes taxes & fees
Sep 21 - Sep 22
Sleep Inn Orangeburg

9. Country living lake style near Santee

Country living lake style near Santee
Summerton
CA $132
CA $295 total
includes taxes & fees
Sep 8 - Sep 9
Country living lake style near Santee

10. Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
Orangeburg
CA $110
CA $122 total
includes taxes & fees
Sep 1 - Sep 2
Travelodge by Wyndham Orangeburg
View all properties

Choose what matters most at family-friendly hotels in Santee

Breakfast included
Pool
All-inclusive
4 stars
5 stars

Top Santee Hotel Reviews

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

10/10 Excellent
"Love the location very friendly and clean. I love they have high security on site"
fern 1-night trip
Posted 2 days ago
Travelodge by Wyndham Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

10/10 Excellent
"The room was exceptional, the breakfast was great, the staff was very friendly great Customer Service! Will be returning!"
Noelia 1-night trip
Posted 3 days ago
Hampton Inn Santee-I-95
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

10/10 Excellent
"Clean room"
Mohammad 2-night trip
Posted 5 days ago
Comfort Inn & Suites Santee
Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95

8/10 Good
"The price rate was great"
Stevenson 3-night trip
Posted 2 weeks ago
Ramada by Wyndham Santee I-95

Frequently asked questions

What's Santee like for family-friendly vacations?
The welcoming destination of Santee is a great choice if you've been thinking about a vacation with the kids. The excursions, lake views, and golfing are just a few things that make this an attractive vacation spot for families. Arrange a flight into Columbia Metropolitan Airport (CAE), which is located 49 mi (78.8 km) from the city center.
What's the best place to stay for families in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another choice for your stay with the kids.
When's the best time to book a family-friendly vacation in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's there to see and do with your family in Santee?
While you and the family are vacationing in Santee, you might want to check out some of the attractions here such as Orangeburg County Library Mentor Branch, Lake Marion, and Edisto Memorial Gardens. Make sure you have lots of time for activities like Congaree National Park and Santee National Wildlife Refuge.

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