Santee River Dam on Lake Marion, South Carolina, Aerial drone view of electric power lines

Find Family Hotels in Santee, SC from CA $89

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Check availability on Santee Family Hotels

Tonight
Aug 25 - Aug 26
Tomorrow
Aug 26 - Aug 27
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

Our top choices for Santee family-friendly hotels

1. Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
  • Family vacation paradise with an outdoor pool, fitness centre, and quiet, pet-friendly atmosphere for your whole family.
CA $152
CA $169 total
includes taxes & fees
Sep 20 - Sep 21
Best Western Plus Santee Inn

2. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee
  • A family escape that offers vibrant pool days, premium entertainment, and free breakfast just minutes from Santee State Park.
CA $191
CA $212 total
includes taxes & fees
Sep 9 - Sep 10
Fairfield Inn & Suites by Marriott Santee

3. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
  • Family-friendly escape at Santee with seasonal outdoor pool, free breakfast, and steps from the state park.
CA $139
CA $154 total
includes taxes & fees
Sep 20 - Sep 21
Comfort Inn & Suites Santee

4. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
Santee
CA $88
CA $98 total
includes taxes & fees
Aug 27 - Aug 28
Travelodge by Wyndham Santee

5. Econo Lodge Santee

Econo Lodge Santee
Santee
CA $87
CA $97 total
includes taxes & fees
Sep 20 - Sep 21
Econo Lodge Santee

6. Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Santee
CA $139
CA $453 total
includes taxes & fees
Aug 31 - Sep 1
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

7. Red Roof Inn Orangeburg

Red Roof Inn Orangeburg
Orangeburg
CA $80
CA $89 total
includes taxes & fees
Aug 31 - Sep 1
Red Roof Inn Orangeburg

8. Country living lake style near Santee

Country living lake style near Santee
Summerton
CA $131
CA $292 total
includes taxes & fees
Aug 26 - Aug 27
Country living lake style near Santee

9. Peach Tree Inn

Peach Tree Inn
St. George
CA $94
CA $102 total
includes taxes & fees
Sep 24 - Sep 25
Peach Tree Inn

10. Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
Orangeburg
CA $109
CA $121 total
includes taxes & fees
Aug 26 - Aug 27
Travelodge by Wyndham Orangeburg
View all properties

Choose what matters most at family-friendly hotels in Santee

Breakfast included
Pool
All-inclusive
4 stars
5 stars

Top Santee Hotel Reviews

Best Western Plus Santee Inn

Best Western Plus Santee Inn

8/10 Good
"Good location. Room was fine. Everything looked in working order. If traveling, it provides a comfortable night and a good breakfast in the morning"
Mark 1-night trip
Posted 1 hour ago
Best Western Plus Santee Inn
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

10/10 Excellent
"Staff friendly and helpful. Room was clean, breakfast was good. Location was convenient."
Esperanza 1-night trip
Posted 1 day ago
Comfort Inn & Suites Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

10/10 Excellent
"Excellent"
Andrew 1-night trip
Posted 2 days ago
Hampton Inn Santee-I-95
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

8/10 Good
"The staff was very helpful and respectful."
Mark 4-night trip
Posted 7 days ago
Travelodge by Wyndham Santee
Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95

8/10 Good
"The price rate was great"
Stevenson 3-night trip
Posted 11 days ago
Ramada by Wyndham Santee I-95

Frequently asked questions

What's Santee like for family-friendly vacations?
The welcoming destination of Santee is a great choice if you've been thinking about a vacation with the kids. The excursions, lake views, and golfing are just a few things that make this an attractive vacation spot for families. Arrange a flight into Columbia Metropolitan Airport (CAE), which is located 49 mi (78.8 km) from the city center.
What's the best place to stay for families in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another choice for your stay with the kids.
When's the best time to book a family-friendly vacation in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's there to see and do with your family in Santee?
While you and the family are vacationing in Santee, you might want to check out some of the attractions here such as Orangeburg County Library Mentor Branch, Lake Marion, and Edisto Memorial Gardens. Make sure you have lots of time for activities like Congaree National Park and Santee National Wildlife Refuge.

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