What's it like in Guadalupe District?

You'll be sure to have fun visiting Santa Fe's Guadalupe District neighborhood. Be sure to check out Santa Fe Railyard and Santa Fe Farmers Market as part of your Guadalupe District travel plans.

What's the best accommodation in Guadalupe District?

Based on Expedia customer reviews, Guadalupe Inn is the highest ranked property in Guadalupe District. This hotel is a short 14-minute walk from Santa Fe Plaza, and it offers free breakfast and free WiFi.

How many hotels will I find in the Guadalupe District area?

If you're searching for places to stay in Santa Fe, Expedia has something to meet your needs with 67 Guadalupe District hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in Guadalupe District, will I receive a refund?

Yes! The majority of room reservations are fully refundable as long as you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to view the top deals on offer in Guadalupe District.

What can I see and do in this Santa Fe neighborhood?

Sights like TAI Modern, El Museo Cultural, and Art Vault can be part of your cultural tour of Guadalupe District. As you're discovering the neighborhood, Santa Fe Railyard and Santa Fe Farmers Market are some other places worth a visit. SITE Santa Fe, Santuario De Nuestra Senora de Guadalupe, and Harrell House of Natural Oddities and Bug Museum are just a few of the places to visit in and around Guadalupe District. While you're out sightseeing, Andrea Fisher Fine Pottery and Lensic Performing Arts Center are a couple of additional sights to visit in Santa Fe.

How can I get around Guadalupe District and the greater Santa Fe area?

If you want to head out of town, you can hop aboard a train at Santa Fe Depot.

10 Best Hotels in Guadalupe District, Santa Fe for 2026

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Our top choices for Guadalupe District hotels

Honeymoon Suite (Room 11, Upstairs) | Deep soaking bathtub

Guadalupe Inn

Guadalupe District

Linda

CA $152 total

includes taxes & fees

Mar 29 - Mar 30

Cities Of Gold Casino

23.5 km from Guadalupe District

Josh

CA $94 total

includes taxes & fees

Apr 5 - Apr 6

Inn at Santa Fe, SureStay Collection by Best Western

Southside, 11 km from Guadalupe District

Bryan

CA $111 total

includes taxes & fees

Apr 2 - Apr 3

Coyote South

Southside, 6.4 km from Guadalupe District

Darshan

CA $100 total

includes taxes & fees

Apr 1 - Apr 2

The Sage Hotel

Don Diego, 0.6 km from Guadalupe District

Dalton

CA $104 total

includes taxes & fees

Apr 1 - Apr 2

Design Loft, 2 Bedrooms, Balcony, City View | Living area

The Mystic Santa Fe

Southside, 4.6 km from Guadalupe District

Tina

CA $133 total

includes taxes & fees

Mar 16 - Mar 17

Standard Room, 2 Queen Beds, Non Smoking

Quality Inn Santa Fe New Mexico

Southside, 6.9 km from Guadalupe District

Jacob

CA $106 total

includes taxes & fees

Mar 22 - Mar 23

Hotel Inn Santa Fe

Southside, 5.2 km from Guadalupe District

Lashonda

CA $88 total

includes taxes & fees

Mar 19 - Mar 20

Ramada by Wyndham Santa Fe

Southside, 6.6 km from Guadalupe District

Milton

CA $113 total

includes taxes & fees

Apr 12 - Apr 13

La Quinta Inn by Wyndham Santa Fe

Southside, 8.3 km from Guadalupe District

Mary

CA $124 total

includes taxes & fees

Mar 30 - Mar 31

King's Rest Court Inn

Southside, 2.3 km from Guadalupe District

David

CA $109 total

includes taxes & fees

Apr 1 - Apr 2

Blackout drapes, iron/ironing board, free WiFi, bed sheets

Econo Lodge Inn & Suites Santa Fe South

Southside, 7.2 km from Guadalupe District

Ted

CA $125 total

includes taxes & fees

Mar 23 - Mar 24

Baymont by Wyndham Santa Fe

Southside, 8.1 km from Guadalupe District

Val

CA $128 total

includes taxes & fees

Mar 23 - Mar 24

Indoor pool, seasonal outdoor pool, cabanas (surcharge), pool umbrellas

Hilton Santa Fe Buffalo Thunder

19.9 km from Guadalupe District

Carlos Guillermo

CA $171 total

includes taxes & fees

Mar 30 - Mar 31

Cottonwood Court Motel

2.9 km from Guadalupe District

Tanya

CA $103 total

includes taxes & fees

Mar 16 - Mar 17

Motel 6 Santa Fe

Southside, 5.2 km from Guadalupe District

Lathaniel

CA $113 total

includes taxes & fees

Mar 23 - Mar 24

Suite, 1 King Bed with Sofa bed, Non Smoking

Comfort Inn Santa Fe South

Southside, 8.4 km from Guadalupe District

Loretta

CA $154 total

includes taxes & fees

Mar 22 - Mar 23

Hampton Inn & Suites Los Alamos White Rock

28.2 km from Guadalupe District

Daniel

CA $175 total

includes taxes & fees

Apr 4 - Apr 5

Holiday Inn Express & Suites Santa Fe by IHG

Southside, 6.3 km from Guadalupe District

Walter

CA $185 total

includes taxes & fees

Mar 29 - Mar 30

Best Western Plus Inn of Santa Fe

Southside, 6.8 km from Guadalupe District

Joli

CA $171 total

includes taxes & fees

Mar 30 - Mar 31

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Where to stay in Guadalupe District

Find the best Guadalupe District areas and neighborhoods for the activities you enjoy most. Learn more about Guadalupe District

New Mexico Museum of Art which includes a statue or sculpture and art

Downtown Santa Fe

Visitors to Downtown Santa Fe rave about its fascinating museums, popular shops, and acclaimed art galleries. You might also want to make some time to see Lensic Performing Arts Center or Georgia O'Keefe Museum while you're exploring the neighborhood.

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Historic Eastside

While visiting Historic Eastside, you might make a stop by sights like Canyon Road and Edition ONE Gallery.

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Santa Fe #artmuseum #newmexico #santafe #santafenm

Southside

Southside is known for its popular shops, and with sights like Meow Wolf and International Museum of Collage, Assemblage & Construction, you won't get bored spending a day wandering around this part of Santa Fe.

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The annual burning of Zozobra (Old Man Gloom) is a lively Santa Fe tradition that includes live music and fireworks along with setting fire to a large paper marionette filled with scrawlings of all the bad that people wish to leave behind.

Northeast Santa Fe

If you're looking for some top things to see and do in Northeast Santa Fe and surrounding area, you can visit New Mexico Museum of Art and Cathedral Basilica of Saint Francis of Assisi.

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