Guadalupe District

Santa Fe

A train station with tracks, a Santa Fe Railway building, and wooden poles.
A church with a cross on top, a bell tower, and a sign that reads "San Miguel."
A wooden water tower labeled "Santa Fe Rail Yard" with a crowd of people and a bicycle in the foreground.
A statue of an angel atop a tiled archway with inscriptions.
A train station named 'Santa Fe Railyard' with a covered waiting area and a platform.

Stay near popular Guadalupe District attractions

Santa Fe Railyard

8.8/10 (1,473 reviews)
During your visit to Santa Fe, you can do some window-shopping at Santa Fe Railyard. Experience the fascinating museums and acclaimed art scene in this romantic area.
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Things to do

Meow Wolf's House of Eternal Return

Meow Wolf's House of Eternal Return

CA $52
per adult
72% of travellers recommend
Meow Wolf's House of Eternal Return
Santa Fe: Meow Wolf's House of Eternal Return Ticket

Santa Fe: Meow Wolf The House of Eternal Return Ticket

CA $52
per adult
100% of travellers recommend
Santa Fe: Meow Wolf The House of Eternal Return Ticket
Santa Fe Jewish Roots Guided History Walking Tour

Santa Fe Jewish Roots Guided History Walking Tour

CA $56
per adult
Santa Fe Jewish Roots Guided History Walking Tour
Tumbleroot Brewery and Distillery Tour and Tasting

Tumbleroot Brewery and Distillery Tour and Tasting

CA $35
per adult
100% of travellers recommend
Tumbleroot Brewery and Distillery Tour and Tasting
Willa Cather's Walking Tour in Santa Fe

Willa Cather's Walking Tour in Santa Fe

CA $71
per adult
Willa Cather's Walking Tour in Santa Fe
Santa Fe: Canyon Road Arts District Walking Tour

Santa Fe: Canyon Road Art & History Walking Tour

CA $99
per adult
100% of travellers recommend
Santa Fe: Canyon Road Art & History Walking Tour
See all activities in Santa Fe

Guadalupe District Hotel Deals

Guadalupe Inn

Guadalupe Inn

2 out of 5
604 Agua Fria St. Santa Fe NM
The price is CA $157 per night from Nov 10 to Nov 11
CA $157
CA $185 total
Nov 10 - Nov 11
includes taxes & fees
Stay at this hotel in Santa Fe. Enjoy free WiFi, parking (surcharge), and a business center. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (1,005 reviews)
"Charming hotel! The room was very clean and comfortable. The fireplace and outside seating area was a nice extra. The bed was so cozy I didn't want to get up. Very convenient to the square and railyard areas. Walking distance. Amos at the front desk was super helpful."

Reviewed on Oct 26, 2026

Guadalupe Inn
Perfect downtown location in historic district- 9.5 walk score! Historic home.

Perfect downtown location in historic district- 9.5 walk score! Historic home.

Santa Fe NM
Book a stay at this family-friendly vacation home in Santa Fe. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Santa Fe Plaza and Loretto ...
9.8/10 Exceptional! (123 reviews)
"What a wonderful location in a cozy, quiet neighborhood close to everything. The furnishings made the place feel some welcoming and homey."

Reviewed on Oct 21, 2026

Get rates
Perfect downtown location in historic district- 9.5 walk score! Historic home.
The Sage Hotel

The Sage Hotel

3 out of 5
725 Cerrillos Rd Santa Fe NM
The price is CA $93 per night from Nov 3 to Nov 4
CA $93
CA $128 total
Nov 3 - Nov 4
includes taxes & fees
Book a stay at this business-friendly hotel in Santa Fe. Enjoy an outdoor pool, room service, and a 24-hour fitness center. Our guests praise the breakfast and ...
8/10 Very good! (2,808 reviews)
"Great place to stay, the staff was wonderful."

Reviewed on Oct 27, 2026

The Sage Hotel
Eldorado Hotel & Spa

Eldorado Hotel & Spa

4 out of 5
309 W San Francisco Street Santa Fe NM
The price is CA $225 per night from Nov 22 to Nov 23
CA $225
CA $308 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this spa hotel in Santa Fe. Enjoy a full-service spa, 2 hot tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,630 reviews)
"Great hotel"

Reviewed on Oct 27, 2026

Eldorado Hotel & Spa
Coyote South

Coyote South

3.5 out of 5
3358 Cerrillos Rd Santa Fe NM
The price is CA $90 per night from Oct 29 to Oct 30
CA $90
CA $117 total
Oct 29 - Oct 30
includes taxes & fees
Book a stay at this business-friendly hotel in Santa Fe. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very good! (3,575 reviews)
"Always a good stay"

Reviewed on Oct 27, 2026

Coyote South
Hilton Santa Fe Buffalo Thunder

Hilton Santa Fe Buffalo Thunder

4 out of 5
20 Buffalo Thunder Trl Santa Fe NM
The price is CA $217 per night from Nov 22 to Nov 23
CA $217
CA $248 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this spa resort in Santa Fe. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the helpful staff and the clean rooms ...
Hilton Santa Fe Buffalo Thunder
See all 1,688 properties in Guadalupe District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Guadalupe District

Find the best Guadalupe District areas and neighborhoods for the activities you enjoy most. Learn more about Guadalupe District
Learn more about Guadalupe District
A building with a distinctive architectural style, featuring a tower and a covered entrance.

Downtown Santa Fe

Visitors to Downtown Santa Fe rave about its fascinating museums, popular shops, and acclaimed art galleries. You might also want to make some time to see Lensic Performing Arts Center or Georgia O'Keefe Museum while you're exploring the neighborhood.
A building with the sign 'Palace of the Governors' and flags hanging overhead.

Southside

Southside is known for its popular shops, and with sights like Meow Wolf and Regal Santa Fe Place, you won't get bored spending a day wandering around this part of Santa Fe.
A building with a sign reading "Burro Alley" and a horse statue in front.
Photo by Kaysha Riggs
Open Photo by Kaysha Riggs

Historic Eastside

While visiting Historic Eastside, you might make a stop by sights like Canyon Road and Skateboard Park.
A church with two bell towers and a large circular window.

Northeast Santa Fe

If you're looking for some top things to see and do in Northeast Santa Fe and surrounding area, you can visit New Mexico Museum of Art and Cathedral Basilica of Saint Francis of Assisi.
A winding road through a mountainous landscape with dense greenery and distant hills.

North Hills

While North Hills might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Skateboard Park and Canyon Road.

Guadalupe District

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