Guadalupe District

Santa Fe

A train station with tracks, a Santa Fe Railway building, and wooden poles.
A church with a cross on top, a bell tower, and a sign that reads "San Miguel."
A wooden water tower labeled "Santa Fe Rail Yard" with a crowd of people and a bicycle in the foreground.
A statue of an angel atop a tiled archway with inscriptions.
A train station named 'Santa Fe Railyard' with a covered waiting area and a platform.

Stay near popular Guadalupe District attractions

Santa Fe Railyard

8.8/10 (1,473 reviews)
During your visit to Santa Fe, you can do some window-shopping at Santa Fe Railyard. Experience the fascinating museums and acclaimed art scene in this family-friendly area.
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Things to do

Meow Wolf's House of Eternal Return

Meow Wolf's House of Eternal Return

CA $54
per adult
80% of travellers recommend
Meow Wolf's House of Eternal Return
Santa Fe: Meow Wolf's House of Eternal Return Ticket

Santa Fe: Meow Wolf The House of Eternal Return Ticket

CA $52
per adult
100% of travellers recommend
Santa Fe: Meow Wolf The House of Eternal Return Ticket
Santa Fe Self-Guided Walking Audio Tour

Santa Fe Self-Guided App-Based Walking Audio Tour

CA $21
per traveller
100% of travellers recommend
Santa Fe Self-Guided App-Based Walking Audio Tour
Tumbleroot Brewery and Distillery Tour and Tasting

Tumbleroot Brewery and Distillery Tour and Tasting

CA $35
per adult
100% of travellers recommend
Tumbleroot Brewery and Distillery Tour and Tasting
Santa Fe: Canyon Road Arts District Walking Tour

Santa Fe: Canyon Road Art & History Walking Tour

CA $99
per adult
100% of travellers recommend
Santa Fe: Canyon Road Art & History Walking Tour
Make Your Own Stained Glass Honeycomb

Make Your Own Stained Glass Honeycomb

CA $142
per adult
Make Your Own Stained Glass Honeycomb
See all activities in Santa Fe

Guadalupe District Hotel Deals

Guadalupe Inn

Guadalupe Inn

2 out of 5
604 Agua Fria St. Santa Fe NM
The price is CA $226 per night from Aug 23 to Aug 24
CA $226
CA $265 total
Aug 23 - Aug 24
includes taxes & fees
Stay at this hotel in Santa Fe. Enjoy free WiFi, parking (surcharge), and a business center. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (1,007 reviews)
"Awesome room. Excellent home made breakfast."

Reviewed on Jul 28, 2026

Guadalupe Inn
The Sage Hotel

The Sage Hotel

3 out of 5
725 Cerrillos Rd Santa Fe NM
The price is CA $89 per night from Aug 24 to Aug 25
CA $89
CA $123 total
Aug 24 - Aug 25
includes taxes & fees
Book a stay at this business-friendly hotel in Santa Fe. Enjoy an outdoor pool, room service, and a 24-hour fitness center. Our guests praise the breakfast and ...
8/10 Very good! (2,558 reviews)
"Great a/c and WiFi…………………………"

Reviewed on Jul 29, 2026

The Sage Hotel
Eldorado Hotel & Spa

Eldorado Hotel & Spa

4 out of 5
309 W San Francisco Street Santa Fe NM
The price is CA $253 per night from Aug 23 to Aug 24
CA $253
CA $341 total
Aug 23 - Aug 24
includes taxes & fees
Book a stay at this spa hotel in Santa Fe. Enjoy a full-service spa, 2 hot tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
Eldorado Hotel & Spa
La Fonda on the Plaza

La Fonda on the Plaza

4 out of 5
100 E San Francisco St Santa Fe NM
The price is CA $418 per night from Aug 2 to Aug 3
CA $418
CA $481 total
Aug 2 - Aug 3
includes taxes & fees
Book a stay at this luxury hotel in Santa Fe. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the restaurant and the helpful staff in our ...
9.4/10 Exceptional! (1,237 reviews)
"Room was great with authentic art."

Reviewed on Jul 28, 2026

La Fonda on the Plaza
Coyote South

Coyote South

3.5 out of 5
3358 Cerrillos Rd Santa Fe NM
The price is CA $97 per night from Aug 24 to Aug 25
CA $97
CA $126 total
Aug 24 - Aug 25
includes taxes & fees
Book a stay at this business-friendly hotel in Santa Fe. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very good! (3,372 reviews)
"Was very comfortable and affordable. Loved the friendly staff, the centralized location and the gym. The walls are really thin and I could hear the neighbors coughing. It wasn’t a huge problem for me and could be for some. The complimentary breakfast is very nice too."

Reviewed on Jul 29, 2026

Coyote South
Inn and Spa at Loretto

Inn and Spa at Loretto

4 out of 5
211 Old Santa Fe Trail Santa Fe NM
The price is CA $375 per night from Aug 24 to Aug 25
CA $375
CA $485 total
Aug 24 - Aug 25
includes taxes & fees
Book a stay at this business-friendly hotel in Santa Fe. Enjoy breakfast (surcharge), a fitness center, and onsite spa services. Our guests praise the restaurant ...
9.2/10 Wonderful! (1,019 reviews)
"Excellent location, great restaurant and the staff is very friendly and helpful"

Reviewed on Jul 29, 2026

Inn and Spa at Loretto
See all 1,679 properties in Guadalupe District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Guadalupe District

Find the best Guadalupe District areas and neighborhoods for the activities you enjoy most. Learn more about Guadalupe District
Learn more about Guadalupe District
A sculpture in front of a building with a unique architectural style.

Downtown Santa Fe

Visitors to Downtown Santa Fe rave about its fascinating museums, popular shops, and acclaimed art galleries. You might also want to make some time to see Santa Fe Plaza or Lensic Performing Arts Center while you're exploring the neighborhood.
A building with the sign 'Palace of the Governors' and flags hanging overhead.

Southside

Southside is known for its popular shops, and with sights like Meow Wolf and Recursos de Santa Fe, you won't get bored spending a day wandering around this part of Santa Fe.
A Turner Carroll Gallery with a red door and a metal roof.

Historic Eastside

While visiting Historic Eastside, you might make a stop by sights like Canyon Road and ViVO Contemporary.
A church with two bell towers and a large circular window.

Northeast Santa Fe

If you're looking for some top things to see and do in Northeast Santa Fe and surrounding area, you can visit Santa Fe Plaza and New Mexico Museum of Art.
A historic church with a large circular window and two towers.

South Capitol

If you're spending some time in South Capitol, Center for Contemporary Arts and New Mexico Military Museum are top sights worth seeing.

Guadalupe District

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