4 Stars Hotels in Otay Mesa, San Diego from CA $178

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Check availability on Otay Mesa 4 Star Hotels

Our top choices for Otay Mesa 4-star hotels

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (3,406 reviews)
"Great place!"
United States
Eliseo
The price is CA $233
CA $336 total
includes taxes & fees
Apr 5 - Apr 6
Hard Rock Hotel San Diego

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2,897 reviews)
"We loved our stay. The staff was helpful and accommodating. The breakfast was top notch. "
United States
Connie
The price is CA $257
CA $372 total
includes taxes & fees
Apr 2 - Apr 3
Manchester Grand Hyatt San Diego

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay
8.6 out of 10, Excellent, (2,446 reviews)
"Clean rooms and well maintained resort."
United States
Derek
The price is CA $270
CA $382 total
includes taxes & fees
Apr 5 - Apr 6
Paradise Point Resort & Spa

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1,616 reviews)
"Great ocean view!"
United States
Louis
The price is CA $234
CA $341 total
includes taxes & fees
Apr 5 - Apr 6
Hyatt Regency Mission Bay Spa and Marina

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
Downtown San Diego
8.4 out of 10, Very good, (6,051 reviews)
"Great rooms & location"
Canada
Priscilla
The price is CA $197
CA $275 total
includes taxes & fees
Apr 5 - Apr 6
Wyndham San Diego Bayside

San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter
4.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (1,666 reviews)
"Great stay"
United States
Manuel
The price is CA $218
CA $253 total
includes taxes & fees
Apr 2 - Apr 3
San Diego Marriott Gaslamp Quarter

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
University Heights
9.2 out of 10, Wonderful, (1,516 reviews)
"Very trendy hotel. Highly recommend this place "
United States
Patricia
The price is CA $311
CA $357 total
includes taxes & fees
Mar 17 - Mar 18
Lafayette Hotel & Club

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
Harbor Island
8.4 out of 10, Very good, (3,371 reviews)
"Beautiful resort! Clean, well decorated and sights are stunning - will stay again! "
Canada
Emily
The price is CA $170
CA $255 total
includes taxes & fees
Apr 1 - Apr 2
Sheraton San Diego Resort

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2,089 reviews)
"The location of this is top notch, and the decoration is fantastic."
United States
Emmanuel
The price is CA $265
CA $368 total
includes taxes & fees
Apr 3 - Apr 4
Omni San Diego Hotel at the Ballpark

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1,366 reviews)
"Clean room, excellent friendly staff, comfortable beds"
Canada
Shauna
The price is CA $293
CA $408 total
includes taxes & fees
Apr 5 - Apr 6
San Diego Mission Bay Resort

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2,034 reviews)
"Outstanding hotel! Friendly courteous staff and amazing room with breathtaking view. "
United States
Jonny
The price is CA $249
CA $353 total
includes taxes & fees
Apr 5 - Apr 6
Marriott Marquis San Diego Marina

The Westin San Diego Bayview

The Westin San Diego Bayview
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1,155 reviews)
"Great hotel great location smells like 5 star wahoo Best espresso martini we ever had at their bar by the way!"
United States
Angela
The price is CA $207
CA $279 total
includes taxes & fees
Apr 5 - Apr 6
The Westin San Diego Bayview

Hotel Indigo San Diego-Gaslamp Quarter by IHG

Hotel Indigo San Diego-Gaslamp Quarter by IHG
4.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (1,007 reviews)
"Clean room, convenient location"
United States
Nicholas
The price is CA $219
CA $307 total
includes taxes & fees
Apr 5 - Apr 6
Hotel Indigo San Diego-Gaslamp Quarter by IHG

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2,941 reviews)
"Nice staff, good location, nice hotel."
United States
Yuke
The price is CA $225
CA $259 total
includes taxes & fees
Apr 6 - Apr 7
Legacy Resort Hotel & Spa

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
Downtown San Diego
9.4 out of 10, Exceptional, (757 reviews)
"Great room had a great time very quiet and nice hotel lovely View"
United States
Tyrell
The price is CA $153
CA $216 total
includes taxes & fees
Apr 5 - Apr 6
Sentral Gaslamp Quarter

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
Mission Valley
8.4 out of 10, Very good, (1,561 reviews)
"Clean and great staff "
United States
Peter
The price is CA $155
CA $178 total
includes taxes & fees
Apr 6 - Apr 7
DoubleTree by Hilton Hotel San Diego - Mission Valley

Hotel del Coronado, Curio Collection by Hilton

Hotel del Coronado, Curio Collection by Hilton
4.0 star property
Historic Downtown Coronado
8.6 out of 10, Excellent, (1,011 reviews)
"Excellent weather, service and atmosphere."
United States
Thomas
The price is CA $680
CA $830 total
includes taxes & fees
Mar 28 - Mar 29
Hotel del Coronado, Curio Collection by Hilton

Westgate Hotel

Westgate Hotel
4.5 star property
Downtown San Diego
9.2 out of 10, Wonderful, (1,002 reviews)
"Specious room, very nice gym and spa. "
United States
Sanae Kusakabe
The price is CA $195
CA $273 total
includes taxes & fees
Apr 5 - Apr 6
Westgate Hotel

San Diego Marriott Mission Valley

San Diego Marriott Mission Valley
4.0 star property
Mission Valley
8.8 out of 10, Excellent, (1,005 reviews)
"It was okay. "
United States
Mirada
The price is CA $203
CA $233 total
includes taxes & fees
Apr 5 - Apr 6
San Diego Marriott Mission Valley

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (424 reviews)
"Nice room, great location, "
United States
Juan Carlos Ramirez
The price is CA $177
CA $205 total
includes taxes & fees
Apr 5 - Apr 6
Courtyard by Marriott San Diego Downtown Little Italy
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Frequently asked questions

How much does it cost to stay in a 4-star hotel in Otay Mesa?
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What's the difference between 5-star and 4-star hotels in Otay Mesa?
Offering a welcoming guest experience and upmarket décor, 4-star hotels are an excellent option for your Otay Mesa vacation. These types of accommodations generally feature lots of handy amenities that make it easy to kick back and relax — think complimentary bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to indulge you in exclusive perks and amenities. Concierge assistance, complimentary toiletries and world-class dining are typically included at these swanky retreats.
Does Otay Mesa have any 4-star all-inclusive resorts?
Finding your dream resort in Otay Mesa is as easy as typing in your travel details and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your meals, room, entertainment and activities, or choose a standard 4-star resort in or around this top destination.

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