Otay Mesa
San Diego
Popular places to visit
San Diego Zoo
See nature up-close and personal at one of the country’s largest and most educational zoos.
San Diego Convention Center
During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's fascinating museums and acclaimed art scene.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
USS Midway Museum
Experience the thrills and hardships of Navy life at this waterfront museum which has become a San Diego landmark.
SeaWorld
Animal interaction, entertaining rides and informative exhibits are all on offer at this family favorite destination.
Things to do
Crossing Borders: Tijuana Day Trip from San Diego
Tour of San Diego>Rosarito >Giant Christ>Puerto Nuevo Lobster
Crossing Borders: Tijuana Day Trip from San Diego
Taco Tuesday Hop to Tijuana from San Diego
From Tijuana: Valle de Guadalupe Shared Winery Tour
Otay Mesa Hotel Deals
The Sofia Hotel
When I arrived at the hotel the First Lady was very nice. Went into my room tv not working. Called and inform within 10 mins of checking in. During a 3 hour waiting period we called an additional 2x for the tv to be fixed. Asked for face towels (hand wash cloths) whichever term you prefer. They brought ...
Reviewed on May 10, 2026
Paradise Point Resort & Spa
Room was cl
Reviewed on May 8, 2026
Manchester Grand Hyatt San Diego
Great location and clean hotel.
Reviewed on May 9, 2026
Hard Rock Hotel San Diego
Stayed here for a weekend, have never stayed at a Hard rock hotel. The location is in a very busy area where you can walk around several places in the downtowns Gaslamp area Front desk was busy but once helped they answered any questions I had.
Reviewed on May 10, 2026
The DEXTRO Little Italy, BW Premier Collection
nice rooms, interesting architecture
Reviewed on May 10, 2026
Wyndham San Diego Bayside
The bed had stains on it. We checked in around 10/11 am. They said they would text us when the room was ready. That never happened. Instead we went back to the hotel and had to wait in an hour line to be told they didn’t have a room for us at all. The lady had to contact her manager to see if they ...
Reviewed on May 10, 2026
Other neighbourhoods around Otay Mesa
Gaslamp Quarter
Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.
Downtown San Diego
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
North Park
North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.
Little Italy
Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
Mission Valley
Boasting major shopping malls like Fashion Valley Mall and Westfield Mission Valley, this area offers entertainment and historic sites such as Mission San Diego de Alcalá and Presidio Park. Easily accessible via the San Diego Trolley system's Green Line.
