Book The Best Hotels in Southeastern Indiana for 2026 from CA $93 - Fully Refundable Options

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Go beyond your typical stay in Southeastern Indiana

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Our top choices for Southeastern Indiana hotels

A spacious living room with grey sofas, a glass coffee table, a fireplace, and a chandelier.

1. Ramada by Wyndham Sellersburg/Louisville North

Sellersburg

Michael

CA $123 total

includes taxes & fees

Nov 22 - Nov 23

An indoor dining area with tables and chairs, large windows, and a brick wall.

2. Hilton Garden Inn Jeffersonville Louisville North

Jeffersonville

Tirana

CA $175 total

includes taxes & fees

Nov 28 - Nov 29

A hotel room with two beds, a desk, a chair, and a nightstand with a lamp.

3. Spark by Hilton Sellersburg

Sellersburg

Charles

CA $130 total

includes taxes & fees

Dec 1 - Dec 2

A Red Roof Inn lobby with two leather armchairs, a small table, and a potted plant.

4. Red Roof Inn Georgetown, IN - Louisville West

Georgetown

Michael

CA $105 total

includes taxes & fees

Dec 1 - Dec 2

A hotel room with two beds, a TV, a desk, and a chair.

5. Comfort Inn & Suites Clarksville - Louisville North

Clarksville

Yvonne

CA $178 total

includes taxes & fees

Dec 6 - Dec 7

A breakfast bar with a sign reading "HAPPY BREAKFAST STARTS HERE," a coffee machine, and various food items.

6. Hampton Inn New Albany Louisville West

New Albany

Wayne

CA $155 total

includes taxes & fees

Nov 23 - Nov 24

A vending machine with snacks and drinks, located in a hotel lobby with seating and a reception area.

7. Hampton Inn Louisville-North/Clarksville

Clarksville

Michael

CA $161 total

includes taxes & fees

Dec 6 - Dec 7

A hotel room with two beds, a desk, a chair, a lamp, and a window with blinds.

8. Holiday Inn Express & Suites Louisville N - Jeffersonville by IHG

Jeffersonville

Michael

CA $164 total

includes taxes & fees

Dec 7 - Dec 8

A modern bar area with wooden bar stools, pendant lighting, and artwork on the walls.

9. Fairfield Inn & Suites by Marriott Louisville New Albany IN

New Albany

Haley

CA $178 total

includes taxes & fees

Nov 22 - Nov 23

A covered entrance with a bench and a trash can, flanked by stone pillars and a building entrance.

10. SureStay by Best Western Salem

Salem

Victoria

CA $117 total

includes taxes & fees

Nov 11 - Nov 12

A hotel room with a flat-screen TV, a desk, a sofa, a small table, and a patterned carpet.

11. Knights Inn and Suites Salem

Salem

Charles

CA $120 total

includes taxes & fees

Nov 10 - Nov 11

A grand entrance with a staircase leading to a door, flanked by two lamp posts and a bench.

12. The Pepin Mansion Historic B&B

New Albany

David

CA $153 total

includes taxes & fees

Nov 12 - Nov 13

13. Days Inn & Suites by Wyndham Sellersburg

Sellersburg

Gina

CA $109 total

includes taxes & fees

Nov 12 - Nov 13

A hotel lobby with a large mural, seating area, and a reception desk.

14. Quality Inn Corydon

Corydon

Lillyith

CA $119 total

includes taxes & fees

Dec 6 - Dec 7

A hotel room with a bed, a desk, a chair, a sofa, and a bench.

15. HavenPointe Inn & Suites

Scottsburg

Nandini

CA $112 total

includes taxes & fees

Dec 10 - Dec 11

An outdoor patio with a fire feature, seating, and a covered area with string lights.

16. Home2 Suites by Hilton Clarksville Louisville North

Clarksville

Tracy

CA $175 total

includes taxes & fees

Nov 20 - Nov 21

A modern interior with a fireplace, wooden panel wall, bar area, and kitchen with coffee machines.

17. Hampton Inn & Suites Scottsburg

Scottsburg

Alexander

CA $184 total

includes taxes & fees

Nov 20 - Nov 21

An outdoor patio area with a fire pit, seating, and string lights.

18. Holiday Inn Express & Suites Scottsburg by IHG

Scottsburg

Deb

CA $166 total

includes taxes & fees

Nov 20 - Nov 21

A multi-story hotel with a prominent "Candlewood Suites" sign, featuring a brick facade and a central entrance with glass doors.

19. Candlewood Suites Louisville North by IHG

Clarksville

Stephanie

CA $150 total

includes taxes & fees

Nov 29 - Nov 30

A hotel lobby with a fireplace, seating area, and a dining space with round tables and chairs.

20. Red Roof Inn Charlestown

Charlestown

Jason

CA $121 total

includes taxes & fees

Dec 1 - Dec 2

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Stay near popular Southeastern Indiana attractions

A river with a bridge, a stadium, and modern buildings.

KFC Yum Center

8.8/10 (1,621 reviews)

Catch an event at KFC Yum Center during your trip to Louisville. Stroll along the riverfront or attend a sporting event in the area.

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Learn more about Southeastern Indiana

Live music, a scenic riverfront, and sights from Deam Lake State Recreation Area to Huber’s Orchard, Winery & Vineyards—discover it all in Southeastern Indiana.

See all hotels in Southeastern Indiana

A riverboat with multiple decks and passengers, docked near a bridge.

Top Southeastern Indiana Hotel Reviews

A spacious living room with a green sofa, a leather armchair, and a wooden coffee table. A brick wall and a chandelier are visible.

The Chandler Hotel

Madison Historic District

10/10 Excellent

Zdravko

The Pepin Mansion Historic B&B

New Albany

10/10 Excellent

Bob

A modern hotel with a 'Stay Apt Suites' sign, featuring a brick facade, large windows, and a parking lot.

stayAPT Suites Louisville North-Clarksville

Clarksville

10/10 Excellent

Darlene

A modern bar area with a long counter, multiple stools, and a well-stocked liquor display.

Fairfield Inn & Suites Madison Historic Eagle Cotton Mill

Madison Historic District

10/10 Excellent

Patrick

A wooden staircase with a balustrade leading to a landing.

Market Street Inn

Jeffersonville

10/10 Excellent

Elisabeth

Hilton Garden Inn Jeffersonville Louisville North

Jeffersonville

10/10 Excellent

Christopher

A bar area with multiple seating options and a large display of liquor bottles.

Derby City Gaming & Hotel - A Churchill Downs Property (Adults Only)

Louisville

10/10 Excellent

Lisa

An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.

Hotel Distil, Autograph Collection

Downtown Louisville

10/10 Excellent

Our stay at Hotel Distil in Louisville was nothing short of exceptional—truly one of the best hotel experiences we’ve ever had. From the moment we arrived, the reception team was incredibly friendly, quick, and efficient, making check-in seamless after a long day of travel. The room itself was stunning—spotlessly clean with beautiful, high-end finishes and thoughtfully curated products that made everything feel luxurious and comfortable. We also had dinner at the on-site steakhouse, and it was...

BROOKE

A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.

Stellar Suites

Downtown Louisville

10/10 Excellent

Jeff

A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

The Grady

Downtown Louisville

10/10 Excellent

The hotel is beautiful and centrally located on the main street near the food and bars. The staff was very helpful, including Chase who set up my wheelchair accessible room ahead of time with my lift and took care of any needs during the day. Really a great overall experience and I wish we could’ve stayed longer! I’d happily book this again. The accessible room was excellent. It had a big bathroom with a roll in shower. The bed was lifted off the ground so I was able to put a Hoyer lift in the...

Jeffrey

A brick building with outdoor seating and a fire pit.

TownePlace Suites by Marriott Louisville North

Jeffersonville

10/10 Excellent

Shelley

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Find hotels in Southeastern Indiana from CA $93

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Go beyond your typical stay in Southeastern Indiana

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Our top choices for Southeastern Indiana hotels

1. Ramada by Wyndham Sellersburg/Louisville North

2. Hilton Garden Inn Jeffersonville Louisville North

3. Spark by Hilton Sellersburg

4. Red Roof Inn Georgetown, IN - Louisville West

5. Comfort Inn & Suites Clarksville - Louisville North

6. Hampton Inn New Albany Louisville West

7. Hampton Inn Louisville-North/Clarksville

8. Holiday Inn Express & Suites Louisville N - Jeffersonville by IHG

9. Fairfield Inn & Suites by Marriott Louisville New Albany IN

10. SureStay by Best Western Salem

11. Knights Inn and Suites Salem

12. The Pepin Mansion Historic B&B

13. Days Inn & Suites by Wyndham Sellersburg

14. Quality Inn Corydon

15. HavenPointe Inn & Suites

16. Home2 Suites by Hilton Clarksville Louisville North

17. Hampton Inn & Suites Scottsburg

18. Holiday Inn Express & Suites Scottsburg by IHG

19. Candlewood Suites Louisville North by IHG

20. Red Roof Inn Charlestown

Stay near popular Southeastern Indiana attractions

KFC Yum Center

Learn more about Southeastern Indiana

Top Southeastern Indiana Hotel Reviews

The Chandler Hotel

10/10 Excellent

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