Best Hotels Near Ohio River Valley, from CA $105

A person standing near a rusted boat in a wooded area with a narrow waterway.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Ohio River Valley hotels

A hotel room with two beds, a blue accent wall, a wooden headboard, and a wall-mounted light fixture.

A gym with exercise equipment, a treadmill, and a mirror reflecting the room.

A laundry area with two front-loading washing machines, a metal cart, and a window with blinds.

A conference room with tables and chairs, a flat-screen TV mounted on the wall, and large windows with sheer curtains.

1. Baymont by Wyndham La Grange KY Southeast

9.5 km from Ohio River Valley

Brittany

CA $108

CA $122 total

includes taxes & fees

Sep 13 - Sep 14

A lobby with a wooden ceiling, a beige sofa, two armchairs, a patterned rug, and a reception desk.

A hotel room with a coffee machine, a bed with white bedding, and a modern pendant light.

A Holiday Inn Express & Suites building with a modern design, a covered entrance, and a parking lot.

A hotel lobby with a sofa, chairs, a small table, and artwork on the walls.

2. Holiday Inn Express & Suites La Grange by IHG

10 km from Ohio River Valley

Joseph

CA $152

CA $172 total

includes taxes & fees

Sep 30 - Oct 1

A spacious lobby with a reception desk, seating area, and a staircase leading to upper floors.

A modern hotel lobby with a grey sofa set, a glass coffee table with a wooden base, and large windows offering a view of the parking lot and greenery outside.

A hotel room with a large bed, a desk, a TV, and a bathroom visible through an open door.

A Best Western hotel with a covered entrance, large windows, and a parking lot.

3. Best Western Ashbury Inn

9.3 km from Ohio River Valley

ross

CA $112

CA $126 total

includes taxes & fees

Sep 30 - Oct 1

A modern restaurant with a mix of booth seating and tables, a wooden accent wall, and a tiled floor.

A gym with multiple treadmills and elliptical machines, equipped with digital displays.

An indoor swimming pool with clear water, surrounded by lounge chairs and a sunshade.

A Drury Inn & Suites hotel with a covered entrance, multiple floors, and a parking area.

4. Drury Inn & Suites Louisville North

27.7 km from Ohio River Valley

kristine

CA $136

CA $160 total

includes taxes & fees

Sep 21 - Sep 22

A reception area with a counter, a digital screen, and a cart with a water dispenser.

A compact kitchenette with two refrigerators stocked with beverages and snacks, and shelves with packaged goods.

A hotel breakfast area with a buffet setup, including a toaster, a bread machine, and a cereal dispenser.

A hotel room with a blue sofa, a brown ottoman, a bed, and framed pictures on the wall.

5. Comfort Inn & Suites La Grange - Louisville Area

9.5 km from Ohio River Valley

Joannie

CA $122

CA $152 total

includes taxes & fees

Sep 21 - Sep 22

6. Spark by Hilton La Grange

9.5 km from Ohio River Valley

Troy

CA $112

CA $127 total

includes taxes & fees

Sep 21 - Sep 22

An outdoor patio with stone walls, a flat-screen TV, a fire pit, and outdoor seating.

A lobby with two patterned armchairs, a reception desk, a large painting, and a glass door leading outside.

A modern hotel entrance with a covered walkway, potted plants, and a sign indicating a parking area.

A hotel room with a large bed, a desk, a chair, a sofa, and a patterned curtain.

7. Hampton Inn Louisville - Northeast

25.9 km from Ohio River Valley

Scott

CA $123

CA $145 total

includes taxes & fees

Oct 11 - Oct 12

A modern kitchen with a coffee machine, waffle maker, and a refrigerator.

A Red Roof Inn with a covered entrance, stone pillars, and a clear sky.

A room with a kitchenette, a flat-screen TV mounted on a wooden cabinet, and a wall-mounted television displaying a sports game.

A hotel room with a desk, a chair, a TV mounted on the wall, and a wooden cabinet.

8. Red Roof Inn Charlestown

34.4 km from Ohio River Valley

Charlie

CA $108

CA $122 total

includes taxes & fees

Sep 14 - Sep 15

A hotel room with a bed, a sofa, a desk, and a painting on the wall.

A modern lounge area with seating, a bar, and a television screen.

A spacious lobby with a checkered carpet, modern seating, a large screen displaying jockeys, and a vibrant ceiling light design.

9. La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd

22.7 km from Ohio River Valley

Gleendalyn

CA $122

CA $143 total

includes taxes & fees

Sep 21 - Sep 22

A modern living room with a stone fireplace, a flat-screen TV, and a sofa.

A modern kitchen with a microwave, coffee maker, and a large refrigerator.

A hotel reception area with a modern design, featuring a mosaic wall, a reception desk, and a digital display.

A hotel room with two beds, a desk, a TV, and a window.

10. Quality Inn Carrollton

33.1 km from Ohio River Valley

Teresa

CA $100

CA $110 total

includes taxes & fees

Oct 10 - Oct 11

An indoor dining area with tables and chairs, large windows, and a brick wall.

A Hilton Garden Inn hotel with a modern facade, multiple floors, and a well-lit entrance.

A display of local treats and beverages, including a sign for 'local delights' and various packaged goods.

A bar area with a counter, bar stools, a television, and shelves stocked with liquor bottles and glasses.

11. Hilton Garden Inn Jeffersonville Louisville North

38.5 km from Ohio River Valley

Natalie

CA $156

CA $177 total

includes taxes & fees

Oct 10 - Oct 11

A modern bar area with a long counter, multiple stools, and a well-stocked liquor display.

A covered outdoor seating area with wicker furniture and a brick building in the background.

A modern bar area with a variety of liquor bottles and glasses, a seating area with leather sofas and chairs, and a large window providing natural light.

A spacious living area with a stone wall, modern furniture, and large windows offering a view of the outdoors.

12. Fairfield Inn & Suites Madison Historic Eagle Cotton Mill

40.8 km from Ohio River Valley

Gregory

CA $195

CA $225 total

includes taxes & fees

Sep 20 - Sep 21

A modern bar area with a long counter, multiple seating options including bar stools and round tables, and pendant lighting.

A buffet with various fruits and condiments.

A modern lobby with a reception desk, seating area, and a geometric wall design.

A modern kitchen with a central island, stainless steel appliances, and a dark door.

13. Hyatt House Louisville East

30.9 km from Ohio River Valley

Victoria

CA $152

CA $179 total

includes taxes & fees

Sep 30 - Oct 1

A hot tub area with a pool, seating, and a bar.

A hotel room with a large bed, a TV, a desk with a chair, and a patterned carpet.

A restaurant with a large table and chairs, large windows, and a staircase.

A hotel room with a kitchenette, a flat-screen TV, a desk with a chair, and a patterned rug.

14. Drury Inn & Suites Louisville East

31.9 km from Ohio River Valley

Jesse

CA $135

CA $159 total

includes taxes & fees

Sep 30 - Oct 1

A Comfort Inn hotel with a gas station attached, featuring a stone facade and multiple windows.

A covered outdoor seating area with picnic tables and benches, surrounded by landscaped gardens and trees.

A modern hotel lobby with a blue sofa, a fireplace, a television, and a dining area.

A hotel room with a bed, a desk with a television, a chair, and a window with curtains.

15. Comfort Inn Madison near Clifty Falls

43.1 km from Ohio River Valley

David

CA $138

CA $158 total

includes taxes & fees

Oct 11 - Oct 12

A breakfast station with yogurt, oatmeal, fruit, and protein options.

A 24/7 market area with a variety of snacks and beverages, a breakfast display, and a Hilton Honors counter.

A modern lounge area with seating arrangements, including sofas, chairs, and a hanging chair.

A modern hotel reception area with a wooden reception desk, a digital screen, and a view of the outdoors.

16. Tru by Hilton Louisville East

29.4 km from Ohio River Valley

Mark

CA $153

CA $180 total

includes taxes & fees

Sep 14 - Sep 15

A hotel lobby with a dining area, seating, and artwork on the walls.

A Hampton Inn & Suites with a covered entrance and a parking lot.

A hotel reception desk with a digital kiosk, a large poster, and a snack bar in the background.

A hotel room with two beds, a desk, a chair, a TV, and a window with blinds.

17. Hampton Inn & Suites Louisville East

28.9 km from Ohio River Valley

Brian

CA $125

CA $147 total

includes taxes & fees

Oct 11 - Oct 12

A row of vending machines with various beverages and snacks.

A hotel room with a television, a lamp, a desk, and a chair.

A Red Roof Inn with a clear entrance, a flag, and a well-lit parking area.

A kitchen counter with various food items and appliances, including a coffee machine, a bread dispenser, and a toaster.

18. Red Roof Inn Carrollton

33.2 km from Ohio River Valley

Ariel

CA $95

CA $105 total

includes taxes & fees

Sep 20 - Sep 21

A modern lobby with a fireplace, seating area, and a reception desk.

An outdoor seating area with a fire feature, a sofa, and a table.

A hotel lobby with a reception desk, a coffee machine, a refrigerator, and a framed artwork on the wall.

A modern lobby with a reception desk, two armchairs, a large abstract wall art, a potted plant, and a fireplace.

19. Fairfield Inn & Suites by Marriott Louisville Northeast

27 km from Ohio River Valley

David

CA $181

CA $213 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with a bed, a desk with a TV, a chair, a window with curtains, and an air conditioning unit.

A Hampton Inn hotel with a modern facade, multiple entry points, and a parking lot with cars.

A Hampton Inn hotel with a modern design, featuring a prominent neon sign, multiple parking spaces, and a well-lit entrance.

20. Hampton Inn Louisville East/Hurstbourne

29.6 km from Ohio River Valley

Carl Anthony

CA $160

CA $188 total

includes taxes & fees

Sep 13 - Sep 14

View all properties

Compare popular hotels close to Ohio River Valley

Property	Star rating	Guest rating
Baymont by Wyndham La Grange KY Southeast	9.4 Exceptional 47 reviews	View
Holiday Inn Express & Suites La Grange by IHG	9.0 Wonderful 898 reviews	View
Best Western Ashbury Inn	8.2 Very good 1,001 reviews	View
Drury Inn & Suites Louisville North	9.6 Exceptional 1,030 reviews	View
Comfort Inn & Suites La Grange - Louisville Area	7.6 Good 410 reviews	View

Top Ohio River Valley Hotel Reviews

Radisson Hotel Louisville North

10/10 Excellent

"❤️❤️"

Holiday Inn Express & Suites Louisville Downtown by IHG

10/10 Excellent

"Good everything"

The Brown Hotel

10/10 Excellent

"What a fantastic hotel! It was raining, so we didn’t get to walk around much, so we stayed in the hotel for drinks and dinner. Both were wonderful!"

Drury Inn & Suites Louisville East

10/10 Excellent

"Always enjoy our stay at Drury Hotels!"

Clarion Pointe Louisville East

10/10 Excellent

"It was a great experience"

Hyatt House Louisville East

10/10 Excellent

"Room was quite clean and well equipped. The bathroom plumbing was a little wonky- the toilet kept running and the shower would randomly drip water but those are very minor inconveniences. The bed was quite comfy but the couch pull out bed was the standard coils with a thin covering. Not even comfy for a 7 year old. Kitchen amenities were fantastic. Would definitely stay again."

Other attractions near Ohio River Valley

Henderson Towhead

Commune with nature and explore the great outdoors at Henderson Towhead during your travels in Henderson. Stroll along the riverfront or experience the art scene in this family-friendly area.

See properties

Atkinson Park

After visiting Atkinson Park, make a plan to see the other sights and activities in Henderson. Experience the art scene and festivals in this family-friendly area.

See properties

Henderson Municipal Golf Course

Enjoy a round of golf in Henderson at Henderson Municipal Golf Course. Experience the art scene and festivals in this family-friendly area.

See properties

Methodist Hospital

Though Methodist Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Henderson while you are here.

See properties

John James Audubon State Park

8.8/10 (41 reviews)

You can take time to visit John James Audubon State Park during your travels to Henderson. Experience the area's festivals and live music.

See properties

Scenic Lake

Commune with nature and explore the great outdoors at Scenic Lake during your travels in Henderson. Stroll along the riverfront or experience the art scene in this family-friendly area.

See properties

Red Banks Park

Explore the great outdoors at Red Banks Park, a lovely green space in Henderson. Experience the art scene and festivals in this family-friendly area.

See properties

Audubon Memorial State Park

You can take time to visit Audubon Memorial State Park during your travels to Henderson. Experience the art scene and festivals in this family-friendly area.

See properties

Frequently asked questions

Can I cancel my hotel reservation on Expedia?

Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Ohio River Valley hotel for you.

How can I save on a Ohio River Valley hotel booking with Expedia?

Before booking your Ohio River Valley hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia.

How much is the nightly rate at a Ohio River Valley hotel?

Prices for hotels in Ohio River Valley often vary, but you can find a great deal from CA $105 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia

Flights to Southern Indiana

Find hotels near Ohio River Valley, from CA $105

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Ohio River Valley hotels

1. Baymont by Wyndham La Grange KY Southeast

2. Holiday Inn Express & Suites La Grange by IHG

3. Best Western Ashbury Inn

4. Drury Inn & Suites Louisville North

5. Comfort Inn & Suites La Grange - Louisville Area

6. Spark by Hilton La Grange

7. Hampton Inn Louisville - Northeast

8. Red Roof Inn Charlestown

9. La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd

10. Quality Inn Carrollton

11. Hilton Garden Inn Jeffersonville Louisville North

12. Fairfield Inn & Suites Madison Historic Eagle Cotton Mill

13. Hyatt House Louisville East

14. Drury Inn & Suites Louisville East

15. Comfort Inn Madison near Clifty Falls

16. Tru by Hilton Louisville East

17. Hampton Inn & Suites Louisville East

18. Red Roof Inn Carrollton

19. Fairfield Inn & Suites by Marriott Louisville Northeast

20. Hampton Inn Louisville East/Hurstbourne

Compare popular hotels close to Ohio River Valley

Top Ohio River Valley Hotel Reviews

Radisson Hotel Louisville North

Holiday Inn Express & Suites Louisville Downtown by IHG

The Brown Hotel

Drury Inn & Suites Louisville East

Clarion Pointe Louisville East

Hyatt House Louisville East

Other attractions near Ohio River Valley

Henderson Towhead

Atkinson Park

Henderson Municipal Golf Course

Methodist Hospital

John James Audubon State Park

Scenic Lake

Red Banks Park

Audubon Memorial State Park

Frequently asked questions

Explore a world of travel with Expedia