Title: Book the Best Ohio River Valley SPA Resorts - Spa Hotels in Ohio River Valley | Expedia.ca [Ohio River Valley Travel Guide](https://expedia.ca/Ohio-River-Valley.dx6233674)[Hotels in Ohio River Valley](https://expedia.ca/Ohio-River-Valley-Hotels.d6233674.Travel-Guide-Hotels)[Vacation Rentals in Ohio River Valley](https://expedia.ca/Ohio-River-Valley-Vacation-Rentals.d6233674.Travel-Guide-VacationRentals)[Flights to Ohio River Valley](https://expedia.ca/Cheap-Flights-To-Ohio-River-Valley.d6233674.Travel-Guide-Flights)[Ohio River Valley Car Rentals](https://expedia.ca/Car-Rentals-In-Ohio-River-Valley.d6233674.Car-Rental-Guide)[Ohio River Valley Vacation Packages](https://expedia.ca/Ohio-River-Valley.d6233674.Destination-Travel-Guides) ![Indianapolis featuring autumn leaves and a cemetery](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/25000/25344-Indianapolis.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Ohio River Valley ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Ohio River Valley Spa Hotels Tonight [Sep 24 - Sep 25](https://www.expedia.ca/Hotel-Search?regionId=6233674&startDate=2025-09-24&endDate=2025-09-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 25 - Sep 26](https://www.expedia.ca/Hotel-Search?regionId=6233674&startDate=2025-09-25&endDate=2025-09-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6233674&startDate=2025-09-26&endDate=2025-09-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6233674&startDate=2025-10-03&endDate=2025-10-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Ohio River Valley Spa Hotels ![Front of property](https://images.trvl-media.com/lodging/84000000/83680000/83672200/83672146/56ddc5d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83680000/83672200/83672146/4dd2e66b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/84000000/83680000/83672200/83672146/0c6dffab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/84000000/83680000/83672200/83672146/d1dac2ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Winds Casino South Bend South Bend 9.6/10 Exceptional (636) "This place is beautiful and the room is very cozy. I truly enjoyed my stay. " CA $148 CA $185 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/South-Bend-Hotels-Four-Winds-Casino-South-Bend.h83672146.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/23000000/22970000/22969000/22968968/0072ba31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/23000000/22970000/22969000/22968968/68bc8841.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/23000000/22970000/22969000/22968968/8b317483.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony view](https://images.trvl-media.com/lodging/23000000/22970000/22969000/22968968/6765b4db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carlisle Inn Walnut Creek Millersburg 9.8/10 Exceptional (1016) "Wonderful place to stay while in Holmes County! " CA $133 CA $151 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/New-Philadelphia-Hotels-Carlisle-Inn-Walnut-Creek.h22968968.Hotel-Information) ![3 bars/lounges](https://images.trvl-media.com/lodging/3000000/2240000/2238900/2238839/27030c05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/3000000/2240000/2238900/2238839/26759110.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2240000/2238900/2238839/48f0074a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2240000/2238900/2238839/904bf0eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Seneca Allegany Resort & Casino Salamanca 9.2/10 Wonderful (1191) "Was a very clean hotel with great staff. " CA $117 CA $152 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/Salamanca-Hotels-Seneca-Allegany-Resort-Casino.h2238839.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1900000/1897400/1897350/b24d7833.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1900000/1897400/1897350/bb3a13f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1900000/1897400/1897350/68aba30b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bicycling](https://images.trvl-media.com/lodging/2000000/1900000/1897400/1897350/6427324b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### I Hotel And Illinois Conference Center Champaign 9.8/10 Exceptional (1822) "Clean rooms, great service and a nice breakfast " CA $140 CA $158 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Champaign-Hotels-I-Hotel-And-Conference-Center.h1897350.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/7000000/6660000/6655300/6655267/b412f678.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite](https://images.trvl-media.com/lodging/7000000/6660000/6655300/6655267/f2a83602.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/7000000/6660000/6655300/6655267/2dfeb189.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Library](https://images.trvl-media.com/lodging/7000000/6660000/6655300/6655267/ca147ebe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carlisle Inn Sugarcreek Sugarcreek 9.8/10 Exceptional (1250) "Love staying here will definitely be back" CA $181 CA $205 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/New-Philadelphia-Hotels-Carlisle-Inn-Sugarcreek.h6655267.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/24000000/23840000/23832100/23832022/a14ac39d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/24000000/23840000/23832100/23832022/e95fa01b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, in-room safe](https://images.trvl-media.com/lodging/24000000/23840000/23832100/23832022/0ece3a73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/24000000/23840000/23832100/23832022/ad59e80e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chautauqua Harbor Hotel - Jamestown Celoron 9.6/10 Exceptional (1012) "Amazing hotel and location. It’s definitely a hidden gem. " CA $199 CA $225 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Celoron-Hotels-Chautauqua-Harbor-Hotel-Jamestown.h23832022.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/80fbdedc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/bea44cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/54f0e03a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/a36c57b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Caesars Southern Indiana Elizabeth 8.2/10 Very good (1020) "Super clean quuet its connected to casino but rooms far enough that was quiet! Comfortable beds and bathroom was suer nive and big! Friendly staff great food!" CA $89 CA $126 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information) ![Hot stone massages, Swedish massages, massages](https://images.trvl-media.com/lodging/119000000/118720000/118717500/118717477/42f2a7d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/119000000/118720000/118717500/118717477/a7916ba6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/119000000/118720000/118717500/118717477/ddd8e206.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/119000000/118720000/118717500/118717477/9dc7e098.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Benchmark Inn Augusta 10/10 Exceptional (1) "Beautiful place. Very clean. Highly recommend. " CA $245 CA $262 total includes taxes & fees Sep 25 - Sep 26 [](https://www.expedia.ca/Augusta-Hotels-The-Benchmark-Inn.h118717477.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/32000000/31900000/31893700/31893660/10ea81f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/32000000/31900000/31893700/31893660/c67046ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/32000000/31900000/31893700/31893660/42d5de61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/32000000/31900000/31893700/31893660/4df12e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Nashville Nashville 8.4/10 Very good (853) "Large comfortable room and kitchenet plus pool and hot tub with easy walk to downtown." CA $139 CA $160 total includes taxes & fees Sep 25 - Sep 26 [](https://www.expedia.ca/Columbus-Hotels-Hotel-Nashville.h31893660.Hotel-Information) ![Massage](https://images.trvl-media.com/lodging/6000000/5770000/5765800/5765762/2bcce859.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/6000000/5770000/5765800/5765762/977e6fff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/6000000/5770000/5765800/5765762/007e0950.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Jetted Tub](https://images.trvl-media.com/lodging/6000000/5770000/5765800/5765762/4e019b99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Brook Pointe Inn Syracuse 8.2/10 Very good (396) "The room was clean, the breakfast food was great, the pool is awesome, the staff are friendly and great, and the area is safe and beautiful. " CA $102 CA $136 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Warsaw-Hotels-Brook-Pointe-Inn.h5765762.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-08&endDate=2025-10-09®ionId=6233674&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Ohio River Valley Hotel Reviews ![Hilton Cincinnati Netherland Plaza](//images.trvl-media.com/lodging/1000000/10000/5900/5818/3a03c8ac_y.jpg) ### Hilton Cincinnati Netherland Plaza 10/10 Excellent "I stayed at this hotel for a conference and loved the historic character of the building. I appreciated having key access to the business center and the location was ideal." [](https://expedia.ca/Cincinnati-Hotels-Hilton-Cincinnati-Netherland-Plaza.h5818.Hotel-Information) ![Ironworks Hotel Indy](//images.trvl-media.com/lodging/20000000/19300000/19294100/19294032/02753ebe_y.jpg) ### Ironworks Hotel Indy 10/10 Excellent "Beautiful design and interestingly appointed rooms. The restaurants in and near the hotel are excellent. Cozy atmosphere." [](https://expedia.ca/Indianapolis-Hotels-Ironworks-Hotel-Indy.h19294032.Hotel-Information) ![I Hotel And Illinois Conference Center](//images.trvl-media.com/lodging/2000000/1900000/1897400/1897350/b24d7833_y.jpg) ### I Hotel And Illinois Conference Center 10/10 Excellent "Very nice and flexible staff when needing room changes!" [](https://expedia.ca/Champaign-Hotels-I-Hotel-And-Conference-Center.h1897350.Hotel-Information) ![Omni Severin Hotel](//images.trvl-media.com/lodging/1000000/20000/17700/17640/3e6b70fc_y.jpg) ### Omni Severin Hotel 10/10 Excellent "always love to stay at the Omni. Right in the center of all the activity. From valet to bar to the breakfast, all perfect!" [](https://expedia.ca/Indianapolis-Hotels-Omni-Severin-Hotel.h17640.Hotel-Information) ![Galt House Hotel Trademark Collection by Wyndham](//images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f_y.jpg) ### Galt House Hotel Trademark Collection by Wyndham 10/10 Excellent "Fastest and easiest check in! Very clean, quiet, and beautiful!" [](https://expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![Sheraton Indianapolis Hotel at Keystone Crossing](//images.trvl-media.com/lodging/1000000/20000/14900/14838/e72753e3_y.jpg) ### Sheraton Indianapolis Hotel at Keystone Crossing 10/10 Excellent "will always stay here! second time!" [](https://expedia.ca/Indianapolis-Hotels-Sheraton-Indianapolis-Hotel-At-Keystone-Crossing.h14838.Hotel-Information) ![Radisson Hotel Cincinnati Riverfront](//images.trvl-media.com/lodging/1000000/10000/2800/2755/68cff2fd_y.jpg) ### Radisson Hotel Cincinnati Riverfront 10/10 Excellent "Comfy bed, amazing view. Overall great stay" [](https://expedia.ca/Cincinnati-Hotels-Radisson-Hotel-Cincinnati-Riverfront.h2755.Hotel-Information) ![Hyatt Regency Cincinnati](//images.trvl-media.com/lodging/1000000/20000/18700/18646/1ec5d305_y.jpg) ### Hyatt Regency Cincinnati 10/10 Excellent "Great location and hotel was in good condition." [](https://expedia.ca/Cincinnati-Hotels-Hyatt-Regency-Cincinnati.h18646.Hotel-Information) ![Wyndham Columbus](//images.trvl-media.com/lodging/1000000/30000/23700/23685/5d4df0e4_y.jpg) ### Wyndham Columbus 10/10 Excellent "Rooms are clean and nice. 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