Title: Best Southeast Missouri Apart hotels from CA $245 | Expedia.ca [Southeast Missouri Travel Guide](https://expedia.ca/Southeast-Missouri.dx6058763)[Hotels in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Vacation Rentals in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Vacation-Rentals.d6058763.Travel-Guide-VacationRentals)[Flights to Southeast Missouri](https://expedia.ca/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.ca/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Southeast Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Missouri.d6058763.Car-Rental-Guide)[Southeast Missouri Vacation Packages](https://expedia.ca/Southeast-Missouri.d6058763.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/9/6538ce9b088c58039b33a5fe701e7a1f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Apart Hotels in Southeast Missouri ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-10-17&endDate=2025-10-19&adults=2&lodging=APART_HOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-11-28&endDate=2025-11-30&adults=2&lodging=APART_HOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-12-26&endDate=2025-12-28&adults=2&lodging=APART_HOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2026-01-23&endDate=2026-01-25&adults=2&lodging=APART_HOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Southeast Missouri Aparthotels ![Exterior](https://images.trvl-media.com/lodging/2000000/1860000/1858600/1858536/94cc7abb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/2000000/1860000/1858600/1858536/77123b3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1860000/1858600/1858536/4e65fabc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1860000/1858600/1858536/2f3d8c4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG De Soto 9.4/10 Exceptional (153) "Enjoyed our short stay, will definitely be back. " CA $249 CA $285 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Farmington-Hotels-Holiday-Inn-Club-Vacations-Timber-Creek-Resort.h1858536.Hotel-Information) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/118000000/117060000/117059500/117059459/2c551ba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, soap, toilet paper](https://images.trvl-media.com/lodging/118000000/117060000/117059500/117059459/18ca813e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast meal](https://images.trvl-media.com/lodging/118000000/117060000/117059500/117059459/07777fb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/118000000/117060000/117059500/117059459/c75c15f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The King Suite at Pickle & Perk Ironton 10/10 Exceptional (1) "Very nice and clean room. The building itself was really cute! The manager was really nice, coffee was really good too! Looking forward to staying again! " CA $187 CA $245 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Ironton-Hotels-The-King-Suite-At-Pickle-Perk.h117059459.Hotel-Information) ![55-inch Smart TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/8010cd32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/06b8cd59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/327c3e44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/84406cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Lofts Perryville 9.2/10 Wonderful (17) "Great place to stay! " [](https://www.expedia.ca/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information) ![Microwave, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/105000000/104400000/104391600/104391549/089b7a70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/105000000/104400000/104391600/104391549/29582e81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/105000000/104400000/104391600/104391549/8765d4e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/105000000/104400000/104391600/104391549/eb763c87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hogan's Hideout Suite is an adorable 3-bedroom rustic suite. Eminence 9.0/10 Wonderful (2) "Property has a handy location right off the highway in town and has plenty of room. The beds were plenty comfortable and there were two additional cots. When we stayed there it was pretty hot so the single window unit struggled to keep up but there were ceiling fans and floor fans that made us more comfortable. Also the refrigerator ran but didn't get cold...we brought this to the owners attention and he was very apologetic and offered us all the ice we needed, which was on site. The living... [](https://www.expedia.ca/Eminence-Hotels-Hogans-Hideout-Suite-Is-An-Adorable-3-Bedroom-Rustic-Suite.h104391549.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-15&endDate=2025-10-16®ionId=6058763&adults=2&lodging=APART_HOTEL&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSoutheast-Missouri-Apart-Hotels.d6058763-aaApartHotels.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSoutheast-Missouri-Apart-Hotels.d6058763-aaApartHotels.Travel-Guide-Accommodation) ## Top Southeast Missouri Hotel Reviews ![The Riverview](//images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "Great view." [](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](//images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 10/10 Excellent "Well lit parking lot " [](https://expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Don’t even bother staying anywhere else. Hands down the best in Sikeston." [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Holiday Inn Express & Suites Perryville by IHG](//images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185_y.jpg) ### Holiday Inn Express & Suites Perryville by IHG 10/10 Excellent "The property was well maintained. Checkin was fast and efficient. Room was clean and comfortable and pillows were great. Breakfast was good. " [](https://expedia.ca/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![The Farmstead Hotel](//images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631_y.jpg) ### The Farmstead Hotel 10/10 Excellent "Very good overall " [](https://expedia.ca/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Festus - St. Louis South](//images.trvl-media.com/lodging/1000000/50000/42200/42120/1887aa70_y.jpg) ### La Quinta Inn & Suites by Wyndham Festus - St. Louis South 10/10 Excellent "Great stay! Friendly staff" [](https://expedia.ca/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information) ![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 10/10 Excellent "Beautiful hotel. Very clean, modern and friendly staff. Definitely would recommend to anyone coming to that area and will stay there every time we visit the city." [](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Everything was clean and looked newly renovated. Staff was friendly. Parking was convenient and the area seemed safe. " [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](//images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 10/10 Excellent "My partner and I were in town for a family wedding and stayed for 3 nights. The staff at this hotel were amazing! They were, over the top, friendly and helpful with anything we needed. They allowed us to gather with family outside on the patio and checked on us several times. The room was clean, the bed was super comfortable, breakfast was great and we loved the patio area. Overall, it was a wonderful experience!" [](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ## Find out more about Southeast Missouri ## Southeast Missouri Aparthotels information | Number of reviews | 155 | | --- | --- | | Accommodation | 4 Aparthotels | | Lowest Price | CA $245 | | Highest Price | CA $285 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [B&B in Annapolis](https://www.expedia.ca/Annapolis-Bed-And-Breakfast.d6282465-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels with Balconies in Annapolis](https://www.expedia.ca/Annapolis-Hotels-Hotels-With-Balconies.0-0-d6282465-tHotelswithBalconies.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Annapolis](https://www.expedia.ca/Annapolis-Hotels-Luxury-Hotel.0-0-d6282465-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Annapolis](https://www.expedia.ca/Annapolis-Hotels-Spa-Hotel.0-0-d6282465-tSpaHotel.Travel-Guide-Filter-Hotels) - 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