Title: The 10 Best Hotels Near Roswell Park Cancer Institute, Buffalo | Expedia.ca [Downtown Buffalo Travel Guide](https://expedia.ca/Buffalo-Downtown-Buffalo.dx6056533)[Roswell Park Cancer Institute Car Rentals](https://expedia.ca/Car-Rentals-In-Roswell-Park-Cancer-Institute.d6175413.Car-Rental-Guide)[Roswell Park Cancer Institute Vacations](https://expedia.ca/Roswell-Park-Cancer-Institute-Downtown-Buffalo.d6175413.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 28 - Jan 29](https://www.expedia.ca/Hotel-Search?regionId=6175413&startDate=2026-01-28&endDate=2026-01-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 29 - Jan 30](https://www.expedia.ca/Hotel-Search?regionId=6175413&startDate=2026-01-29&endDate=2026-01-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6175413&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6175413&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Top Roswell Park Cancer Institute Hotel Reviews ![The Westin Buffalo](https://images.trvl-media.com/lodging/14000000/13460000/13451300/13451237/6f487a3b_y.jpg) ### The Westin Buffalo 10/10 Excellent "Immaculate hotel. All around good service." [](https://expedia.ca/Buffalo-Hotels-The-Westin-Buffalo.h13451237.Hotel-Information) ![Wyndham Garden Buffalo Downtown](https://images.trvl-media.com/lodging/1000000/160000/159000/158959/2e0799e1_y.jpg) ### Wyndham Garden Buffalo Downtown 10/10 Excellent "very clean, staff was very nice and helpful" [](https://expedia.ca/Buffalo-Hotels-Wyndham-Garden-Buffalo-Downtown.h158959.Hotel-Information) ![Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/73c0de62_y.jpg) ### Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG 10/10 Excellent "Clean room " [](https://expedia.ca/Buffalo-Hotels-Holiday-Inn-Express-Suites-Buffalo-Downtown-Medical-CTR.h6258.Hotel-Information) ![Hampton Inn & Suites Buffalo Downtown](https://images.trvl-media.com/lodging/1000000/900000/892600/892571/3b4ec85c_y.jpg) ### Hampton Inn & Suites Buffalo Downtown 10/10 Excellent "Bedroom was large as was the bathroom. Very clean. Big thank you to azjanae and Felicia at the front desk. " [](https://expedia.ca/Buffalo-Hotels-Hampton-Inn-Suites-Buffalo-Downtown.h892571.Hotel-Information) ![Hilton Garden Inn Buffalo Downtown](https://images.trvl-media.com/lodging/9000000/8750000/8745500/8745457/7db896c2_y.jpg) ### Hilton Garden Inn Buffalo Downtown 10/10 Excellent "The staff are so pleasant! The room was beautiful and clean with a nice view of the city! " [](https://expedia.ca/Buffalo-Hotels-Hilton-Garden-Inn-Buffalo-Downtown.h8745457.Hotel-Information) ![Hyatt Regency Buffalo / Hotel and Conference Center](https://images.trvl-media.com/lodging/1000000/30000/23200/23101/00561234_y.jpg) ### Hyatt Regency Buffalo / Hotel and Conference Center 10/10 Excellent "Customer service" [](https://expedia.ca/Buffalo-Hotels-Hyatt-Regency-Buffalo-Hotel-And-Conference-Center.h23101.Hotel-Information) ![Buffalo Guesthouse](https://images.trvl-media.com/lodging/116000000/115340000/115334800/115334773/debc1f3c_y.jpg) ### Buffalo Guesthouse 10/10 Excellent "Maria was the best!! " [](https://expedia.ca/Buffalo-Hotels-Buffalo-Guesthouse.h115334773.Hotel-Information) ![Curtiss Hotel, an Ascend Collection Hotel](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/1b8dbb7d_y.jpg) ### Curtiss Hotel, an Ascend Collection Hotel 10/10 Excellent "Great hotel 5 \*\*\*\*\*" [](https://expedia.ca/Buffalo-Hotels-Curtiss-Hotel.h17038248.Hotel-Information) ![The Mansion On Delaware Ave](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/1225a495_y.jpg) ### The Mansion On Delaware Ave 10/10 Excellent "Very romantic " [](https://expedia.ca/Buffalo-Hotels-The-Mansion-On-Delaware-Ave.h692610.Hotel-Information) ## Hotels near other Roswell Park Cancer Institute attractions ### Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site You can browse the exhibits at Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site, a museum with a storied past, during your trip to Buffalo. Experience the area's entertainment choices and acclaimed theater scene. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6064393) ### Studio Arena Theater Enjoy a performance at Studio Arena Theater, a storied theater in Buffalo. Experience the area's acclaimed theater scene and entertainment choices. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6175349) ### Trinity Episcopal Church You can learn about the history of Buffalo with a stop at Trinity Episcopal Church. Experience the great live music or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558133891) ### Alleyway Theatre You can make plans for a show at Alleyway Theatre during your stay in Buffalo. Experience the acclaimed theater scene and entertainment choices in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532661132) ### Theater of Youth Enjoy a performance at Theater of Youth, a theater with a story to tell in Buffalo. Experience the area's acclaimed theater scene and entertainment choices. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6064441) ### Shea's Performing Arts Center 4.4/5 (152 reviews) Enjoy a show at Shea's Performing Arts Center, a theater with a story to tell in Buffalo. Experience the area's acclaimed theater scene and great live music. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6064405) ### Road Less Traveled Productions Get tickets for a show at Road Less Traveled Productions, a storied theater in Buffalo. Experience the area's acclaimed theater scene and great live music. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532661134) ### Road Less Traveled Theater You can enjoy a show at Road Less Traveled Theater during your stay in Buffalo. Experience the acclaimed theater scene and great live music in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558133888) ## Frequently asked questions ### What are the top-rated hotels near Roswell Park Cancer Institute? > [InnBuffalo off Elmwood](https://www.expedia.ca/Buffalo-Hotels-InnBuffalo-Off-Elmwood.h21856017.Hotel-Information) > > > InnBuffalo off Elmwood boasts an impressive review rating of 10\. This charming Victorian hotel is situated just 3.4 km from Roswell Park Cancer Institute, offering travellers a delightful blend of historical character and modern comforts. Guests can enjoy complimentary breakfast daily, a cozy fireplace, and a relaxing yoga class on-site. Unique features such as deep soaking bathtubs and furnished balconies enhance the experience for travellers seeking tranquility and style. > > > [Buffalo Harmony House](https://www.expedia.ca/Buffalo-Hotels-Buffalo-Harmony-House.h90762810.Hotel-Information) > > > Buffalo Harmony House, rated 10 and holding a 4.5-star rating, is conveniently located just a 16-minute walk from Roswell Park Cancer Institute. This romantic getaway offers travellers a luxurious experience with private hot tubs and a beautifully maintained garden. Guests can indulge in complimentary breakfast and enjoy amenities like a cozy fireplace and arcade game room. The charming ambiance makes it a perfect choice for those looking for a unique and memorable stay. > > > [Carriage House Loft - King Bed and Garage Parking](https://expedia.ca/Buffalo-hotels-Carriage-House-Loft-King-Bed-and-Garage-Parking.h115961056.Hotel-information) > > > Carriage House Loft - King Bed and Garage Parking is another exceptional option with a perfect review rating of 10, located just 2.6 km from Roswell Park Cancer Institute. This historic loft features a fully equipped kitchen, including an oven, refrigerator, and coffee maker, ideal for travellers wanting the comforts of home. Guests can enjoy convenient onsite parking and nearby local museums, making it an excellent choice for those looking to explore Buffalo while staying close to their medical appointments. ### What hotels are within walking distance to Roswell Park Cancer Institute? > [Buffalo Harmony House](https://www.expedia.ca/Buffalo-Hotels-Buffalo-Harmony-House.h90762810.Hotel-Information) > > > Buffalo Harmony House is a charming 4.5-star hotel located just a short 16-minute walk from Roswell Park Cancer Institute. With a perfect review rating of 10, this romantic getaway features luxurious amenities like private hot tubs and premium bedding. Guests can indulge in complimentary daily breakfast and relax in the serene garden area, making it an excellent choice for those seeking a relaxing retreat in Buffalo. > > > [The Mansion On Delaware Ave](https://www.expedia.ca/Buffalo-Hotels-The-Mansion-On-Delaware-Ave.h692610.Hotel-Information) > > > The Mansion On Delaware Ave is an elegant 4-star hotel, just 10 minutes on foot from Roswell Park Cancer Institute. With a review rating of 9.4, this hotel boasts an onsite art gallery and offers complimentary cooked breakfast daily. Guests can enjoy access to fitness facilities and a beautiful terrace, providing a perfect blend of luxury and comfort for their stay. > > > [Summer Street Guest House](https://www.expedia.ca/Buffalo-Hotels-Summer-Street-Guest-House.h110138870.Hotel-Information) > > > The Summer Street Guest House is a cozy 3-star accommodation located a 19-minute walk from Roswell Park Cancer Institute. Rated 10 by travellers, it offers a homely atmosphere with fully equipped kitchens including dishwashers and ovens, perfect for travellers looking to prepare their own meals. The inviting patio provides a lovely space to unwind after a day of exploring. ### How much is a hotel near Roswell Park Cancer Institute? ### What are the most popular family-friendly hotels near Roswell Park Cancer Institute? > [Curtiss Hotel, Ascend Hotel Collection](https://www.expedia.ca/Buffalo-Hotels-Curtiss-Hotel.h17038248.Hotel-Information) > > > Curtiss Hotel, Ascend Hotel Collection is a luxurious 5-star hotel located just an 18-minute walk from Roswell Park Cancer Institute, with a remarkable review rating of 9.2\. This hotel is ideal for families, offering amenities such as connecting rooms, cribs, and kids' meals to ensure a comfortable stay for younger travellers. Additional highlights include a spa with hot springs, a 24-hour fitness centre, and complimentary breakfast, making it a top choice for families seeking relaxation and comfort. > > > [Hilton Garden Inn Buffalo Downtown](https://www.expedia.ca/Buffalo-Hotels-Hilton-Garden-Inn-Buffalo-Downtown.h8745457.Hotel-Information) > > > Hilton Garden Inn Buffalo Downtown is a charming 3-star hotel situated just 1.8 km from Roswell Park Cancer Institute, with a solid review rating of 8.6\. This family-friendly hotel offers amenities such as free cribs, connecting rooms, and kids' meals, ensuring a comfortable stay for families. Guests can relax in the indoor pool, enjoy the onsite restaurant, and take advantage of convenient parking nearby, making it a practical choice for families visiting the area. > > > [Hampton Inn & Suites Buffalo Downtown](https://www.expedia.ca/Buffalo-Hotels-Hampton-Inn-Suites-Buffalo-Downtown.h892571.Hotel-Information) > > > Hampton Inn & Suites Buffalo Downtown, rated 8.8 by travellers, is another excellent family-friendly option located 18 minutes on foot from Roswell Park Cancer Institute. This hotel features spacious rooms with kitchenettes, free cribs, and rollaway beds, perfect for families. Guests can enjoy a complimentary buffet breakfast and take advantage of the indoor pool and hot tub for some fun family time. The 24-hour fitness centre and rooftop garden add to the overall appeal of this welcoming hotel. ### Are there any 5-star hotels near Roswell Park Cancer Institute? > [Curtiss Hotel, Ascend Hotel Collection](https://www.expedia.ca/Buffalo-Hotels-Curtiss-Hotel.h17038248.Hotel-Information) > > > Curtiss Hotel, Ascend Hotel Collection is a luxurious 5-star hotel located just an 18-minute walk from Roswell Park Cancer Institute. With an impressive review rating of 9.2, it offers travellers a serene retreat featuring a full-service spa where they can indulge in Swedish and Hot Stone massages. Travellers will appreciate the complimentary breakfast options, including a continental spread, and the convenience of free valet parking. The hotel also boasts a stunning rooftop terrace and designer toiletries, ensuring a comfortable and upscale experience. ### Which hotels near Roswell Park Cancer Institute offer the best views? > [Buffalo Marriott at LECOM HARBORCENTER](https://www.expedia.ca/Buffalo-Hotels-Buffalo-Marriott-At-LECOM-HARBORCENTER.h9787810.Hotel-Information) > > > Buffalo Marriott at LECOM HARBORCENTER is a 3.5-star hotel just 2.6 km from Roswell Park Cancer Institute, with an impressive review rating of 9.4\. Guests can enjoy breathtaking lake views from the comfort of their rooms, enhancing their stay in Buffalo. The hotel features a fitness centre, daily housekeeping, and a snack bar. Its prime waterfront location is complemented by convenient amenities such as valet parking and a concierge service, making it an excellent choice for travellers looking to relax and enjoy the scenery. > > > [The Richardson Hotel](https://www.expedia.ca/Buffalo-Hotels-Hotel-Henry-Urban-Resort.h18136290.Hotel-Information) > > > The Richardson Hotel, rated 9.0 by travellers, is a charming 3.5-star hotel located 4.8 km from Roswell Park Cancer Institute. Situated in a historical district, this hotel offers delightful resort views that travellers can admire from various viewpoints. With amenities such as a 24-hour fitness facility, self-parking, and beautifully maintained gardens, it provides a cozy and inviting atmosphere for a memorable stay. ### What are the best affordable hotels near Roswell Park Cancer Institute? > [InnBuffalo off Elmwood](https://www.expedia.ca/Buffalo-Hotels-InnBuffalo-Off-Elmwood.h21856017.Hotel-Information) > > > InnBuffalo off Elmwood is a charming Victorian hotel, located just 3.4 km from Roswell Park Cancer Institute, making it a convenient choice for travellers. Rated 10 by travellers, this hotel offers a delightful stay with free breakfast and WiFi. Guests can also enjoy a relaxing yoga class on-site or unwind in the deep soaking bathtubs. The hotel features premium bedding, designer toiletries, and free self-parking, enhancing the overall experience. > > > [Carriage House Loft - King Bed and Garage Parking](https://expedia.ca/Buffalo-hotels-Carriage-House-Loft-King-Bed-and-Garage-Parking.h115961056.Hotel-information) > > > Carriage House Loft is a stylish choice located only 2.6 km from Roswell Park Cancer Institute, with a perfect review rating of 10\. This loft features a fully equipped kitchen, complete with an oven, dishwasher, and a refrigerator, making it ideal for longer stays. Guests can enjoy the convenience of garage parking and nearby duty-free shopping. The charming historic ambiance adds to the appeal of this cozy accommodation. > > > [Summer Street Guest House](https://www.expedia.ca/Buffalo-Hotels-Summer-Street-Guest-House.h110138870.Hotel-Information) > > > Summer Street Guest House has a welcoming atmosphere just a 19-minute walk from Roswell Park Cancer Institute and holds a stellar 10 review rating. With a star rating of 3.0, this traveler house features free WiFi and self-parking. Guests can prepare their own meals in the well-equipped kitchen, complete with a microwave and stovetop, or relax on the inviting patio. With its homey feel, it's a great option for those looking to balance comfort and affordability. ### Are there any hotels with pools close to Roswell Park Cancer Institute? > [Courtyard Buffalo Downtown / Canalside](https://www.expedia.ca/Buffalo-Hotels-Courtyard-Buffalo-Downtown-Canalside.h7901087.Hotel-Information) > > > Just 2.4 km from Roswell Park Cancer Institute, Courtyard Buffalo Downtown / Canalside is a delightful 3-star hotel featuring an accessible indoor pool. This hotel has a solid review rating of 9.0 and offers amenities such as a hot tub, a fitness centre, and nearby golf courses for leisure activities. Guests can appreciate thoughtful touches like free toiletries and self-parking, ensuring a relaxing visit. > > > [Buffalo Guesthouse](https://www.expedia.ca/Buffalo-Hotels-Buffalo-Guesthouse.h115334773.Hotel-Information) > > > Located only a 7-minute walk from Roswell Park Cancer Institute, Buffalo Guesthouse is a charming 3-star hotel offering both outdoor and private in-room pools. With a remarkable review rating of 9.0, travellers can also take advantage of free continental breakfast and cozy amenities like premium bedding and fireplaces. The well-equipped kitchen facilities ensure a comfortable stay for those looking to enjoy their time in Buffalo. > > > [Aloft Buffalo Downtown](https://www.expedia.ca/Buffalo-Hotels-Aloft-Buffalo-Downtown.h31863371.Hotel-Information) > > > Aloft Buffalo Downtown is just an 11-minute walk from Roswell Park Cancer Institute, making it a convenient choice for travellers. This 3-star hotel features an inviting indoor pool, perfect for relaxing after a busy day. Guests can also enjoy a fitness centre available 24 hours, complimentary breakfast, and evening entertainment options. With a review rating of 8.2, this hotel promises a pleasant stay in the heart of Buffalo. ### What are the best pet-friendly hotels near Roswell Park Cancer Institute? > [Comfort Inn](https://expedia.ca/Fort-Erie-hotels-Comfort-Inn.h537917.Hotel-information) > > > Comfort Inn, situated 7.7 km from Roswell Park Cancer Institute, has a solid review rating of 8.4 and is an ideal choice for pet owners. The hotel allows pets and provides amenities such as a free breakfast and connecting rooms. Guests can take advantage of the 24-hour fitness facilities and enjoy a comfortable stay with premium bedding and daily housekeeping. > > > [Hampton Inn & Suites Buffalo Downtown](https://www.expedia.ca/Buffalo-Hotels-Hampton-Inn-Suites-Buffalo-Downtown.h892571.Hotel-Information) > > > Located 18 minutes on foot from Roswell Park Cancer Institute, Hampton Inn & Suites Buffalo Downtown offers a warm welcome to pets and has an impressive travellers' rating of 8.8\. This hotel features pet-friendly amenities, including food and water bowls for your pets. Guests will appreciate the complimentary buffet breakfast, indoor pool, and rooftop garden, making it a perfect spot for relaxation and family gatherings. > > > [Aloft Buffalo Downtown](https://www.expedia.ca/Buffalo-Hotels-Aloft-Buffalo-Downtown.h31863371.Hotel-Information) > > > Aloft Buffalo Downtown is a vibrant 3-star hotel located just an 11-minute walk from Roswell Park Cancer Institute, with an excellent review rating of 8.2\. This pet-friendly hotel welcomes pets and provides essential amenities like food and water bowls, making it an excellent choice for travellers with furry companions. Guests can enjoy an indoor pool, a 24-hour fitness centre, and free Wi-Fi, ensuring a pleasant and convenient stay. ### Can I book a fully refundable hotel close to Roswell Park Cancer Institute? ### Can I find Expedia discounts for hotels near Roswell Park Cancer Institute? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - [3 Star Hotels in Downtown Buffalo ](https://www.expedia.ca/3Star-Downtown-Buffalo-Buffalo-Hotels.s30-n6056533-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Buffalo ](https://www.expedia.ca/5Star-Buffalo-Hotels.s50-0-d602674.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Downtown Buffalo ](https://www.expedia.ca/5Star-Downtown-Buffalo-Buffalo-Hotels.s50-n6056533-0.Travel-Guide-Filter-Hotels) - [Castles in Allen-Medical Campus Station ](https://www.expedia.ca/Allen-Medical-Campus-Station-Castles.d6257222-aaCastles.Travel-Guide-Accommodation) - [Hotels near Allen-Medical Campus Station ](https://www.expedia.ca/Allen-Medical-Campus-Station-Hotels.d6257222.Travel-Guide-Hotels) - 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