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Panama Vacation Packages

Choose two or more items and save on your trip:

Top destinations in Panama

Top Panama Flight + Hotel Deals

Toscana Inn
Courtyard by Marriott Panama Multiplaza Mall
Courtyard by Marriott Panama Metromall
Aloft Panama
Sortis Hotel, Spa & Casino, Autograph Collection

Top Hotels in Panama

TRYP by Wyndham Panamá Centro
TRYP by Wyndham Panamá Centro
3.5 out of 5
Via Veneto, El Cangrejo Bellavista, Panama City, Panama
Free cancellationReserve now, pay when you stay
The price is CA $80 per night from Jul 24 to Jul 24
4.4/5Excellent! (997 reviews)
"Friendly staff both night shift and day shift front desk were lovely to me both men deserved to get recognized. I could have asked for a better staff even the lady at the restaurant greeted us with a huge smile on her face and served breakfast to me and my two daughters thank you for making me feel ..."

Reviewed on Jun. 15, 2021

TRYP by Wyndham Panamá Centro
Crowne Plaza Panama Airport
Crowne Plaza Panama Airport
4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
Free cancellation
The price is CA $117 per night from Jul 23 to Jul 23
4.2/5Very Good! (967 reviews)
"Great location and very relaxing stay. The only thing was the lack of towels but it was a great stay."

Reviewed on Jun. 21, 2021

Crowne Plaza Panama Airport
Royal Decameron Panama All Inclusive
Royal Decameron Panama All Inclusive
3.5 out of 5
KM 115 Carretera, Farallon, Rio Hato, Cocle
Free cancellationReserve now, pay when you stay
The price is CA $179 per night from Jul 4 to Jul 4
3.7/5Good! (789 reviews)
"The resort is pretty big and there is a lot of walking involved to get from one place to the other. The only complaint I have is that there were some loud banging and stumping and door slammed abruptly for hours after 2:00am on our last days of stay. We tried to call the receptionist a few times ..."

Reviewed on May 25, 2021

Royal Decameron Panama All Inclusive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top things to do in Panama

Panama Hotel + Flights

Panama Vacation

While Panama is perhaps best known for its mighty canal, there’s so much more to this Central American country. Visitors will also be wowed by lush rainforests, idyllic beaches, rich indigenous culture and a unique colonial history.

Panama Hotel + Flights

Expedia has 1610 hotels available here starting at CA $80 a night. But if you want to save some serious money, combine your hotel and flights into a Panama Vacation Package. You can also add car rental and activities to your booking to create an unforgettable getaway. With the dollars you save, why not book a tour and visit island paradises or taste famous local flavours like ceviche?

Your Panama Vacation Itinerary

Day 1-2: Start your adventure in the national capital, Panama City, and head straight to Casco Viejo (the Old Quarter). Wander narrow cobblestone streets and discover colourful Spanish colonial houses, beautiful churches and an impressive gastronomic scene. Plan a day trip to the Panama Canal to watch mammoth ships slip through the Miraflores Locks.

Day 3-5: Stay on some of the world’s most spectacular islands in San Blas. Owned and operated by the Kuna people, this untouched paradise on the Caribbean side of Panama is the perfect place to live out your Robinson Crusoe fantasies.

Day 6-8: Head back to Panama City and fly to the mountain town of Boquete. A top destination for outdoor lovers, it offers jungle hikes, whitewater rafting, canopy tours, zip lining and more.

Panama Information

Party with the locals at Carnival, Panama’s largest annual celebration. You’ll find the biggest events in Panama City and Las Tablas.

If you’ll be spending most of your time in the nation’s capital, check out our  Panama City Vacation Packages .

Want to really experience the carefree vibe of this Latin American gem? Book one of our  Panama All Inclusive Resorts  and say adios to vacation planning stress.

Frequently asked questions