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Panama Vacation Packages

Choose two or more items and save on your trip:

Top Panama Flight + Hotel Deals

Valle Escondido Resort Golf and Spa
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2021 Panama vacation deals

Las Americas Golden Tower Panama
The Westin Playa Bonita Panama
Hotel San Remo
Hostal Casa 33
Hotel Caribe
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Top Hotels in Panama

Principe Hotel and Suites
Principe Hotel and Suites
3 out of 5
Via Argentina, Panama City, Panama
Free cancellationReserve now, pay when you stay
The price is CA $66 per night from Oct 30 to Oct 31
4.2/5Excellent! (417 reviews)

"Centrico y atentos. El acceso es muy bueno y el rest de sushi"…"

Reviewed on Aug. 17, 2020

Principe Hotel and Suites
Hyatt Place Panama City/Downtown
Hyatt Place Panama City/Downtown
3.5 out of 5
Avenida Aquilino de la Guardia, between, Vía España and Calle 52 Bella Vista, Panama City, Panama
4.3/5Excellent! (1,000 reviews)
Good location

"Hotel is a little worn but walking distance to restaurants. Has coin laundry on pool level which is great for multiweek travelers. Would.stay again."…"

Reviewed on Mar. 10, 2020

Hyatt Place Panama City/Downtown
Hilton Panama
Hilton Panama
5 out of 5
Balboa Ave. and Aquilino De La Guardia, Panama City, Panama
Free cancellationReserve now, pay when you stay
The price is CA $166 per night from Nov 7 to Nov 8
4.4/5Excellent! (605 reviews)

"Great location and very clean. Confusing elevator system. Expensive drinks."…"

Reviewed on Apr. 1, 2020

Hilton Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top things to do in Panama

Panama Vacation

While Panama is perhaps best known for its mighty canal, there’s so much more to this Central American country. Visitors will also be wowed by lush rainforests, idyllic beaches, rich indigenous culture and a unique colonial history.

Panama Hotel + Flights

Expedia has 1600 hotels available here starting at CA $66 a night. But if you want to save some serious money, combine your hotel and flights into a Panama Vacation Package. You can also add car rental and activities to your booking to create an unforgettable getaway. With the dollars you save, why not book a tour and visit island paradises or taste famous local flavours like ceviche?

Your Panama Vacation Itinerary

Day 1-2: Start your adventure in the national capital, Panama City, and head straight to Casco Viejo (the Old Quarter). Wander narrow cobblestone streets and discover colourful Spanish colonial houses, beautiful churches and an impressive gastronomic scene. Plan a day trip to the Panama Canal to watch mammoth ships slip through the Miraflores Locks.

Day 3-5: Stay on some of the world’s most spectacular islands in San Blas. Owned and operated by the Kuna people, this untouched paradise on the Caribbean side of Panama is the perfect place to live out your Robinson Crusoe fantasies.

Day 6-8: Head back to Panama City and fly to the mountain town of Boquete. A top destination for outdoor lovers, it offers jungle hikes, whitewater rafting, canopy tours, zip lining and more.

Panama Information

Party with the locals at Carnival, Panama’s largest annual celebration. You’ll find the biggest events in Panama City and Las Tablas.

If you’ll be spending most of your time in the nation’s capital, check out our  Panama City Vacation Packages .

Want to really experience the carefree vibe of this Latin American gem? Book one of our  Panama All Inclusive Resorts  and say adios to vacation planning stress.

Frequently asked questions

Q: Which airports can I fly in to for a vacation to Panama?
A: While there are several possibilities, you’re most likely to fly in to one of these two top international terminals in Panama:
  • Panama City (PTY-Tocumen Intl.): 5,337 international flights per month.
  • David (DAV-Enrique Malek Intl.): 13 international flights per month.
Q: What are the most popular types of hotels for a vacation to Panama?
A: Many visitors like to spend their getaways in hotels. Some are fond of the amenities and services of hostels or bed & breakfasts, while others choose to book apartments. Whatever you’re chasing, Panama has options for all budgets.
Q: What does a Panama vacation booking with Expedia include?
A: Car and flight. Flight and hotel. Hotel and car. Flight, hotel and car. You get the gist. You can book as much or as little as you like, all in one place. To get as much as you can out of your Panama vacation, have a look at our experiences and activities while you’re at it.
Q: What is the best way to save money on my vacation to Panama?
A: You’ll be rewarded handsomely when you lock in a Panama vacation package with a little help from Expedia. Bundle your Flights, Hotels and Experiences and enjoy great discounts, like up to 42% off selected properties. You’ll soon be looking at your dream vacation at a price that’ll pleasantly surprise you.
Q: What are the best things to do in Panama?
A: When you’re staying in San Miguelito, don’t miss the chance to check out Metromall Panama. If David is your chosen destination, check out Miguel de Cervantes Saavedra Park. Lastly, Gatun Locks is one attraction that’s high on the must-do list of many vacationers in Colon.