
Santa Clara Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Find the right fit
Rest easy
Your Santa Clara Vacation
Enjoy amazing adventures when you lock in a vacation package to Santa Clara. Whether you're a history buff, art enthusiast or just a traveler who loves discovering new places, there's something for everyone in this lively city. Every trip to Santa Clara needs a well-planned itinerary. Fill yours with big-name attractions like Farallon Island, La Casa de Lourdes Outdoor Spa and Parroquia Santiago Apóstol de Río Hato. Stop dreaming and start traveling. Explore the many options on Expedia today and put your Santa Clara vacation plans in motion!
Top Santa Clara Vacation Deals



Central Hotel Panama Casco Viejo
Reviewed on Jul. 25, 2025


Hotel Plaza Herrera
Reviewed on May 5, 2025
Santa Clara Hotel Deals

Villa Botero By Casa Mojito B&B
Reviewed on Apr. 21, 2025

Las Sirenas de Santa Clara
Reviewed on May 2, 2017

Gran Evenia Bijao & Convention Center
Reviewed on Jul. 29, 2025
Discover the most popular places to visit in Santa Clara

Playa Blanca
Nothing says vacation like spending a lazy day at Playa Blanca, a popular beach in Rio Hato. Amble around this romantic area's seaside or experience its entertainment venues.

Farallón Beach
If a restful vacation is part of your travel plans, Farallón Beach might be the perfect place to seek out during your trip to El Farallón del Chirú. While you're here, you can savor the top-notch restaurants.
Santa Clara Beach
Why not spend a carefree afternoon at Santa Clara Beach during your travels in Rio Hato? Amble around this family-friendly area's seaside or experience its entertainment venues.
What to do in Santa Clara

Private Bike Tour Waterfall, Views & Local Life

Canopy-ziplining Adventures in Anton Valley

Panama City: ATV Jungle Adventure Discover Volcano & Waterfall
Frequently asked questions
Other vacations you might like
- January Vacations and Deals
- February Vacations and Deals
- March Vacations and Deals
- April Vacations and Deals
- May Vacations and Deals
- June Vacations and Deals
- July Vacations and Deals
- August Vacations and Deals
- September Vacations and Deals
- October Vacations and Deals
- November Vacations and Deals
- December Vacations and Deals
Expedia's Latest Trends
- Super 8 by Wyndham Niagara Falls by the Falls
- Best Hotels in Kelowna
- Hotels in Marina Vallarta
- Hotel SonoHotel IDrive District
- Days Inn by Wyndham Vancouver Airport
- Motel6 Hotels in Ottawa
- THE LIVELY TOKYO AZABUJUBAN
- All Inclusive Resorts and Hotels in Turks and Caicos
- Club Wyndham Nashville
- Mandarin Hotel Managed by Centre Point
- The Blue Mountains Hotels with an Indoor Pool
- Hotels with smoking rooms in Vancouver
- Taj Falaknuma Palace
- TownePlace Suites by Marriott Fort McMurray