Santa Clara Vacation Rentals

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Our top choices for Santa Clara vacation rentals

Cozy 1-bedroom apartment in adorable Las Lajas with AC

Cozy 1-bedroom apartment in adorable Las Lajas with AC
Las Lajas
6.0 out of 10, (1 review)
"Took some cleaning, sparse utensils and towels, refrigerator could use a good defrosting. "
United States
Jeff B.
The price is CA $98
CA $153 total
includes taxes & fees
May 13 - May 14
Cozy 1-bedroom apartment in adorable Las Lajas with AC

Enchanting Love Nest la Fortuna. It's a haven of beauty and relaxation.

Enchanting Love Nest la Fortuna. It's a haven of beauty and relaxation.
Altos del Maria
The price is CA $185
CA $283 total
includes taxes & fees
May 13 - May 14
Enchanting Love Nest la Fortuna. It's a haven of beauty and relaxation.

Cabañas Laguna Bella

Cabañas Laguna Bella
2.0 star property
La Laguna
10.0 out of 10, Exceptional, (1 review)
"Clean and spacious with a view! That view is spectacular! Peaceful vibes."
United States
Orestes
The price is CA $167
CA $218 total
includes taxes & fees
May 20 - May 21
Cabañas Laguna Bella

Altavida Lodge · Private Studio with Pool · N6

Altavida Lodge · Private Studio with Pool · N6
Valle de Anton
The price is CA $105
CA $191 total
includes taxes & fees
May 17 - May 18
Altavida Lodge · Private Studio with Pool · N6

Romantic and cozy apartment in tropical villa w/ mountain and flowers view.

Romantic and cozy apartment in tropical villa w/ mountain and flowers view.
Altos del Maria
10.0 out of 10, Exceptional, (1 review)
"As advertised. Quiet, beautiful, and relaxing. Loved the pool"
United States
Donald R.
The price is CA $301
CA $406 total
includes taxes & fees
May 13 - May 14
Romantic and cozy apartment in tropical villa w/ mountain and flowers view.

★ Quinta Pavo Real - The Magic Tree House

★ Quinta Pavo Real - The Magic Tree House
Quinta Pavo Real
8.0 out of 10, Very good, (1 review)
"Hay muchos animales tipo zoológico que andan libres por la propiedad lo que te transporta a otro lugar y te ayuda a desconectar "
Mexico
Franklin
The price is CA $97
CA $172 total
includes taxes & fees
May 13 - May 14
★ Quinta Pavo Real - The Magic Tree House

Heated Pool - 4 bedroom Cottage , Pool Table

Heated Pool - 4 bedroom Cottage , Pool Table
Provincia de Panamá Oeste
The price is CA $390
CA $498 total
includes taxes & fees
May 18 - May 19
Heated Pool - 4 bedroom Cottage , Pool Table

Villa de Montana en Altos del Maria

Villa de Montana en Altos del Maria
sora , Altos del Maria
The price is CA $345
CA $431 total
includes taxes & fees
May 13 - May 14
Villa de Montana en Altos del Maria

Cabanas Potosi, El Valle de Anton, Panama Birders-Nature Lovers-Waterfalls-ETC

Cabanas Potosi, El Valle de Anton, Panama Birders-Nature Lovers-Waterfalls-ETC
El Valle de Anton
9.6 out of 10, Exceptional, (18 reviews)
"We had a fantastic stay. Our cabin was very comfortable in clean. Our host Dennis was most friendly and helpful at all times. Truly enjoyed the beautiful, botanical grounds and the variety of birds we were able to view on the property. Very well maintained. We highly recommend a visit!!"
United States
Tracy B R.
The price is CA $108
CA $146 total
includes taxes & fees
May 14 - May 15
Cabanas Potosi, El Valle de Anton, Panama Birders-Nature Lovers-Waterfalls-ETC

Close to beaches, mountains, waterfalls. Great for nomads. Quiet/rural town.

Close to beaches, mountains, waterfalls. Great for nomads. Quiet/rural town.
Panama Oeste, 00000, PA
The price is CA $95
CA $206 total
includes taxes & fees
May 15 - May 16
Close to beaches, mountains, waterfalls. Great for nomads. Quiet/rural town.

Riomar Luxurious Beachfront Aptartment, 3 bedroom

Riomar Luxurious Beachfront Aptartment, 3 bedroom
San Carlos
The price is CA $308
CA $521 total
includes taxes & fees
May 13 - May 14
Riomar Luxurious Beachfront Aptartment, 3 bedroom

Quiet 1 bedroom house with air conditioning in the charming San Carlos District

Quiet 1 bedroom house with air conditioning in the charming San Carlos District
San Carlos
The price is CA $105
CA $139 total
includes taxes & fees
May 13 - May 14
Quiet 1 bedroom house with air conditioning in the charming San Carlos District

Cozy Condo con piscina en Playa Coronado/Cozy Condo with pool in Coronado

Cozy Condo con piscina en Playa Coronado/Cozy Condo with pool in Coronado
Las Lajas
7.8 out of 10, Good, (10 reviews)
"I stayed for a week in January 2026. Easy access into the building. The security staff were very friendly and helpful. The unit had all the necessities. The unit had a nice breeze and I often kept the air conditioner off during the day. Would recommend for anyone looking to visit Coronado. "
United States
Jeremy G.
The price is CA $86
CA $155 total
includes taxes & fees
May 19 - May 20
Cozy Condo con piscina en Playa Coronado/Cozy Condo with pool in Coronado

Beach Apartment Nikki Steps from the Sea

Beach Apartment Nikki Steps from the Sea
El Chirú
The price is CA $111
CA $207 total
includes taxes & fees
May 13 - May 14
Beach Apartment Nikki Steps from the Sea

Modern Studio for 4 Guests Valle de Antón A1

Modern Studio for 4 Guests Valle de Antón A1
Valle de Anton
The price is CA $105
CA $191 total
includes taxes & fees
May 17 - May 18
Modern Studio for 4 Guests Valle de Antón A1

Linda Vista, Enorme Terraza, Barbacoa y Piscina. Disfruta del Grato Ambiente

Linda Vista, Enorme Terraza, Barbacoa y Piscina. Disfruta del Grato Ambiente
Provincia de Panamá Oeste
The price is CA $376
CA $468 total
includes taxes & fees
May 13 - May 14
Linda Vista, Enorme Terraza, Barbacoa y Piscina. Disfruta del Grato Ambiente

WiFi+Pool+10min 2 Surf+Nature+Private+Quiet

WiFi+Pool+10min 2 Surf+Nature+Private+Quiet
La Ermita
10.0 out of 10, Exceptional, (1 review)
"It was a truly a piece of paradise in many ways. The hosting family works hard to take good care of the property and guests. After staying 10 days, I felt like I've become a part of their extended family. Always remember the key to receive best hospitality is "do unto others what you would have them do unto you.""
United States
HAHN
The price is CA $81
CA $176 total
includes taxes & fees
May 13 - May 14
WiFi+Pool+10min 2 Surf+Nature+Private+Quiet

Wi-Fi+Piscina+10min a surf+Privada+Tranquila+Naturaleza

Wi-Fi+Piscina+10min a surf+Privada+Tranquila+Naturaleza
Panama Oeste Antes de las Torres
The price is CA $95
CA $212 total
includes taxes & fees
May 15 - May 16
Wi-Fi+Piscina+10min a surf+Privada+Tranquila+Naturaleza

COUNTRY HOUSE

COUNTRY HOUSE
El Valle de Antón
The price is CA $335
CA $382 total
includes taxes & fees
May 13 - May 14
COUNTRY HOUSE
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Clara Hotel Reviews

Find out more about Santa Clara

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santa Clara. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find a vacation rental in Santa Clara?

Yes, we offer vacation rentals close to popular sights in Santa Clara, or you can go with a secluded option if you want a relaxing place to stay. Santa Clara is known for its beaches.

What are some of the best vacation rentals in Santa Clara?

Chic 1-bedroom with WiFi and AC in enchanting Río Hato: Visitors like this Santa Clara vacation home rental. It has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings.

How many vacation rentals will I find in Santa Clara?

Choose from 6 Expedia vacation rentals in Santa Clara for a memorable vacation.

What’s there to see and do in Santa Clara?

While exploring the area, visit family-friendly sights like Serpentarium, or get outside and enjoy nature at Playa Blanca. Santa Clara Beach and Farallón Beach are a couple of places you'll find in the larger area.

What’s a vacation rental in Santa Clara like?

Vacation rentals are privately owned properties you can stay in for several days or longer in Santa Clara. Vacation rentals offer amenities such as patios, hot tubs, and fire pits so you'll have all the conveniences of home. If you're concerned about a sanitized environment, a vacation rental can offer a sense of safety away from public hotel elevators and busy concierge desks while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular option for small groups.