Title: Panama Vacation Rentals from CA $125: Short-Term Rentals for 2025 | Expedia.ca

 

[Panama Travel Guide](https://expedia.ca/Panama.dx142)[Panama Hotels](https://expedia.ca/Destinations-In-Panama.d142.Hotel-Destinations)[Panama Flights](https://expedia.ca/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Rentals](https://expedia.ca/Destinations-In-Panama.d142.Car-Rental-Destinations)[Panama Vacations](https://expedia.ca/Panama.d142.Destination-Travel-Guides)

![Panama which includes tropical scenes, island images and landscape views](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by PhotoJoy

# Panama Vacation Rentals

-   ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg)
    
    ### 
    
    Change your mind
    
    Book hotels with free cancellation
    
-   ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)
    
    ### 
    
    Treat yourself
    
    Sign in to save 10% or more on thousands of hotels
    
    [Sign in](https://www.expedia.ca/login)
    
-   ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)
    
    ### 
    
    Be picky
    
    Search almost a million properties worldwide
    

## Top Cities in Panama

![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Panama City

[](https://expedia.ca/Panama-City-Vacation-Rentals.d2897.Travel-Guide-VacationRentals)

![](https://mediaim.expedia.com/destination/1/1d8a91c9ba3e2729b384542dbcd5f2f4.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Colon

[](https://expedia.ca/Colon-Vacation-Rentals.d601867.Travel-Guide-VacationRentals)

![](https://mediaim.expedia.com/destination/2/504facaece8a8de4b5e66a51bfdb8196.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### El Valle de Anton

[](https://expedia.ca/El-Valle-De-Anton-Vacation-Rentals.d6053180.Travel-Guide-VacationRentals)

![](https://mediaim.expedia.com/destination/1/b0242759ce82d4f0d6f5123d7c510e46.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Rio Hato

[](https://expedia.ca/Rio-Hato-Vacation-Rentals.d6246042.Travel-Guide-VacationRentals)

## Top Vacation Rentals in in Panama

![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfa0534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/4e9d4ce1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81f325e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/bba49e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Arcadia Condo Suites

Costa del Este

9.4/10

Exceptional

(142)

"Wonderful place great staff "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shantia

CA $117

CA $194 total

includes taxes & fees

Dec 3 - Dec 4

[](https://www.expedia.ca/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/edba2188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment | Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/568d88f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/a4be5f58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 3 Bedrooms | View from room](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/5cdc54c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Boutique Apartments Panama

Bella Vista

7.8/10

Good

(206)

"The view was amazing and the place was great could stay here again "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Yonnette

[](https://www.expedia.ca/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information)

![Standard Apartment | Living area](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/0a056e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, coffee/tea maker, toaster](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/f71ce331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/20a4e482.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/29d0d0fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Torres de Alba Hotel & Suites

Bella Vista

8.8/10

Excellent

(481)

"Good location, quick walk to the subway."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lynden

CA $130

CA $143 total

includes taxes & fees

Nov 27 - Nov 28

[](https://www.expedia.ca/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information)

![Luxury Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment | Private kitchen](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/041fa75e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/42c91f90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Duplex | Living area](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/32dc2d2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casco View Apartments

Santa Ana

9.2/10

Wonderful

(50)

"Great stay, would recommend."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brooke

[](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information)

![Studio, 1 King Bed, Non Smoking, Connecting Rooms](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/d9012efa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/f0ebed1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/24a7280d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 1 Queen Bed with Sofa bed, Non Smoking, Kitchen](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/faee5c4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Las Clementinas

Casco Viejo

9.4/10

Exceptional

(169)

"Our stay at Las Clementinas was amazing. The ambiance, decor, and central location to all things in Casco Viejo made our trip magical. Not only was the hotel beautiful, the staff was incredibly warm, helpful and welcoming. The restaurant in the hotel was absolutely delicious. I would stay here ten times over. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amanda

CA $175

CA $192 total

includes taxes & fees

Dec 9 - Dec 10

[](https://www.expedia.ca/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/b51e58b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/7a081d75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 2 Bedrooms | Living area](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/48e220ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/a3d62646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Boutique Apartments Panamá Coco del Mar

San Francisco

7.4/10

Good

(150)

"Clean room good place to stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gideon

CA $48

CA $251 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information)

![Superior Double Room | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/c337dae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Queen Suite | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/5b01afd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Double Room | View from room](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/c6d0b885.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite, Annex Building (King) | Private kitchen](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/6bdd4504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Isabela Suites

Casco Viejo

10/10

Exceptional

(165)

"The room was spotless, the location perfect, and the staff was absolutely superb!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gregory

CA $197

CA $217 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information)

![Honeymoon Studio, Hot Tub, Valley View](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/f1920aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exclusive Studio Suite, 1 Queen Bed, Kitchenette, Mountain View | Terrace/patio](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/7a6a1a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/c5c10649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premier Studio Suite, 1 Queen Bed, Kitchenette, Garden Area | In-room dining](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/w4030h2268x0y0-0bf2c10e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa Alejandro

Boquete

8.8/10

Excellent

(125)

"Priced right, easy walk to town, safe, quiet & overall great stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

[](https://www.expedia.ca/Boquete-Hotels-Villa-Alejandro.h46550459.Hotel-Information)

![Deluxe Apartment | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7d5bd8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Apartment | Living area](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/077501d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/f7211254.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premier Apartment | Beach/ocean view](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/a7c64715.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Yoo Panamá by Boutique Apartments

Bella Vista

8.2/10

Very good

(44)

"Great place , very clean all good "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

harley

CA $70

CA $273 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information)

![Apartment (3G) | Balcony](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/b4a2ec38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (3G) | Living area](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/8ac950b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (3G) | Dining room](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/e16a4424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/dc7a8e52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Cuadra by Wynwood House

El Chorrillo

9.2/10

Wonderful

(43)

"Nice place!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tesha

CA $118

CA $173 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Panama-City-Hotels-La-Cuadra-By-Wynwood-House.h100591449.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/1940e046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (11B) | Balcony](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/w2996h2000x4y0-ef85e67f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (09H) | Living area](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/e1902a90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (11I)](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/0f7befd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### San Francisco by Wynwood House

San Francisco

9.2/10

Wonderful

(52)

"This area was perfect for us to walk and check out the local restaurants and coffee shops was really an amazing time! Very close to other major areas so driving and getting around was very convenient:))) all around great stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

mario

CA $139

CA $188 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Panama-City-Hotels-Living-By-Wynwood-House.h100525493.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/576f28cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/26ebabc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/8679b43b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/3fb46571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### ESHEL SUITES PANAMA

San Francisco

10/10

Exceptional

(5)

"Loved the property and the location, it was clean , nice and I really enjoyed my stay there"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Aron

[](https://www.expedia.ca/Panama-City-Hotels-ESHEL-SUITES-PANAMA.h100639469.Hotel-Information)

![Design Suite, 1 King Bed, Mountain View](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/903374ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Studio Suite | Private kitchenette](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/29a7e7da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Suite](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/f86e54de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, 1 King Bed, Garden View | Living area](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/a6c217b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### El Cielo by Villa Alejandro

Boquete

9.6/10

Exceptional

(85)

"Nice stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carlos

[](https://www.expedia.ca/Boquete-Hotels-El-Cielo-By-Villa-Alejandro.h95043574.Hotel-Information)

![Apartment (CC4B) | Balcony](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/64939a66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 2 Bedrooms (CC3B) | Private kitchen](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/5e7a29e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 2 Bedrooms (CC2B) | Living area](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/f49b7db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 2 Bedrooms (CC4A) | Dining room](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/d8108baf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Contemporanea by Wynwood House

Casco Viejo

8.6/10

Excellent

(19)

"Great place!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jad

CA $136

CA $185 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99229225.Hotel-Information)

![Apartment, 2 Bedrooms (CM2) | Private kitchen](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/dfb3f761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 3 Bedrooms (CM5) | Living area](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/3681eb23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 2 Bedrooms (CM4) | Terrace/patio](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/9659c91c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 3 Bedrooms (CM5)](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/f82421c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Mallet by Wynwood House

Casco Viejo

9.8/10

Exceptional

(24)

" It was very relaxing to stay at the historical and cutely renovated apartment. Great aesthetic. Lively apartment, very well decorated! Right the middle of everything in the beautiful town of Casco Veijo. Vibrant lanes, boutique stores, cafes and restaurants near by. We had an amazing time staying for 2 nights at this apartment. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Navyatha

CA $678

CA $817 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99778891.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b12b577d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 2 Bedrooms (8B) | Private kitchen](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/46fac3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 2 Bedrooms (8B) | Private kitchen](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b8e57e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 2 Bedrooms (17B)](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/155ac5ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Boutique Apartments Atlapa

San Francisco

7.8/10

Good

(24)

"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shamia

[](https://www.expedia.ca/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information)

![Deluxe Apartment](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/b8edc80a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Apartment | Living area](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/97957e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment | Private kitchen](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/7d5fb04c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Apartment | Dining room](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/97ac72d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Moderna by Wynwood House

Casco Viejo

7.4/10

Good

(40)

"The nightlife around there was incredible"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Felix

CA $81

CA $125 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Panama-City-Hotels-La-Moderna-By-Wynwood-House.h100587737.Hotel-Information)

![Club Cabin | Living area](https://images.trvl-media.com/lodging/90000000/89430000/89420600/89420538/ceaebfc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/90000000/89430000/89420600/89420538/8ba1e0a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/90000000/89430000/89420600/89420538/8a3c0e30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cookware/dishes/utensils, kitchen islands](https://images.trvl-media.com/lodging/90000000/89430000/89420600/89420538/ecd071fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabañas Naturaleza

Bocas del Toro

9.4/10

Exceptional

(9)

"A lovely property with a beautiful garden area and the owners were great and very helpful. Would highly recommend for anyone looking to stay in bocas del toro but away from the noise of the main town. "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Fiona

[](https://www.expedia.ca/Bocas-Del-Toro-Hotels-Cabanas-Naturaleza.h89420538.Hotel-Information)

![Apartment, 2 Bedrooms (2C)](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/3a166248.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 3 Bedrooms (4B) | Dining room](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/e8a22a58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (1B) | Living area](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/350b1bdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (1A) | Private kitchen](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/56b38ba7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Donovan By Wynwood House

Casco Viejo

8.4/10

Very good

(45)

"I always love to stay at Wynwood properties in Panama "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alberto B

CA $84

CA $128 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Panama-City-Hotels-Donovan-By-Wynwood-House.h100638302.Hotel-Information)

![Outdoor pool, free cabanas, sun loungers](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/a1255d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/32689428.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![City view from property](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/b3283f1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Apartment | Living area](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/a2b1fb98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Yoo Panama & Arts Tower

Bella Vista

9.4/10

Exceptional

(46)

"Nice stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

ANGEL

[](https://www.expedia.ca/Panama-City-Hotels-Apto-35G-Vista-A-La-Ciudad.h83067546.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-10&endDate=2025-12-11&regionId=142&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

Black Friday Sale

Limited-time deals: save up to 50% on select hotels

[Book now](https://expedia.ca/deals?rfrr=VR_BF_PROMO_142)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama.d142.Vacation-Rental-Destinations)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama.d142.Vacation-Rental-Destinations)

## Top Panama Hotel Reviews

![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg)

### Principe Hotel and Suites

10/10 Excellent

"Arrived really early and got the room without a problem. Staff is very courteous. Stayed at this hotel before and its location is the best feature. The hotel needs some TLC since it looks and feels worn down. Doors do not close right; mattress is very uneven, and rooms are very basic. The AC control does not work. Again, location, location. "

[](https://expedia.ca/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information)

![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg)

### Plaza Paitilla Inn Hotel

10/10 Excellent

"Easy parking. Lots of noise from the road"

[](https://expedia.ca/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information)

![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg)

### Las Americas Golden Tower Panama

10/10 Excellent

"Clean room"

[](https://expedia.ca/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information)

![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg)

### The Executive Hotel

10/10 Excellent

"Yes very Good hotel "

[](https://expedia.ca/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information)

![Decapolis Hotel Panama City](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg)

### Decapolis Hotel Panama City

10/10 Excellent

"No desayune"

[](https://expedia.ca/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information)

![The Westin Playa Bonita Panama](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e_y.jpg)

### The Westin Playa Bonita Panama

10/10 Excellent

"The rope in the shower was dirty and should be changed."

[](https://expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information)

![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg)

### Crowne Plaza Panama Airport by IHG

10/10 Excellent

"For an airport hotel, this was lovely! The perfect place for us to recoup after a long day of flying. The pool and outdoor space was wonderful. There isn’t much around in terms of stores or entertainment, but it is quiet and clean."

[](https://expedia.ca/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information)

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg)

### Hotel Riu Plaza Panama

10/10 Excellent

"Everything"

[](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information)

![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg)

### JW Marriott Panama

10/10 Excellent

"Fabulous stay!"

[](https://expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information)

## Find out more about Panama

**Everything you need to know about** **Panama** **vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Panama vacation rental for you. At Expedia, you can take your pick from [private vacation homes](https://www.expedia.ca/aa/PrivateVacationHomes), [apartments](https://www.expedia.ca/aa/Apartments), cottages, [cabins](https://www.expedia.ca/aa/Cabins), villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panama vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

**Panama vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Panama. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Panama vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Panama vacation rentals we have selected for you start as low as CA $125 per night. Entering your travel dates in the search wizard you might find even better deals!

**How to find incredible deals on Panama rentals**

At Expedia, we put the best Panama vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panama vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

## Explore a world of travel with Expedia

-   Popular Panama Cities
-   All accommodation types in Panama

-   [Panama City Vacation Rentals](https://expedia.ca/Panama-City-Vacation-Rentals.d2897.Travel-Guide-VacationRentals)
-   [Bocas del Toro Vacation Rentals](https://expedia.ca/Bocas-Del-Toro-Vacation-Rentals.d6023445.Travel-Guide-VacationRentals)
-   [Rio Hato Vacation Rentals](https://expedia.ca/Rio-Hato-Vacation-Rentals.d6246042.Travel-Guide-VacationRentals)
-   [Boquete Vacation Rentals](https://expedia.ca/Boquete-Vacation-Rentals.d500194.Travel-Guide-VacationRentals)
-   [Colon Vacation Rentals](https://expedia.ca/Colon-Vacation-Rentals.d601867.Travel-Guide-VacationRentals)
-   [El Valle de Anton Vacation Rentals](https://expedia.ca/El-Valle-De-Anton-Vacation-Rentals.d6053180.Travel-Guide-VacationRentals)
-   [Bastimentos Vacation Rentals](https://expedia.ca/Bastimentos-Vacation-Rentals.d829296964305711104.Travel-Guide-VacationRentals)
-   [San Blas Islands Vacation Rentals](https://expedia.ca/San-Blas-Islands-Vacation-Rentals.d6024116.Travel-Guide-VacationRentals)
-   [David Vacation Rentals](https://expedia.ca/David-Vacation-Rentals.d500195.Travel-Guide-VacationRentals)
-   [Playa Coronado Vacation Rentals](https://expedia.ca/Playa-Coronado-Vacation-Rentals.d6053187.Travel-Guide-VacationRentals)
-   [El Chiru Vacation Rentals](https://expedia.ca/El-Chiru-Vacation-Rentals.d553248623142942970.Travel-Guide-VacationRentals)
-   [Nueva Gorgona Vacation Rentals](https://expedia.ca/Nueva-Gorgona-Vacation-Rentals.d6344112.Travel-Guide-VacationRentals)
-   [Punta Chame Vacation Rentals](https://expedia.ca/Punta-Chame-Vacation-Rentals.d6145606.Travel-Guide-VacationRentals)
-   [David Sur Vacation Rentals](https://expedia.ca/David-Sur-Vacation-Rentals.d829296828190040064.Travel-Guide-VacationRentals)
-   [Taboga Vacation Rentals](https://expedia.ca/Taboga-Vacation-Rentals.d6268388.Travel-Guide-VacationRentals)
-   [Pedasí Vacation Rentals](https://expedia.ca/Pedasi-Vacation-Rentals.d6130073.Travel-Guide-VacationRentals)
-   [Playa Bonita Village Vacation Rentals](https://expedia.ca/Playa-Bonita-Village-Vacation-Rentals.d6053186.Travel-Guide-VacationRentals)
-   [Santiago Vacation Rentals](https://expedia.ca/Santiago-Vacation-Rentals.d6191486.Travel-Guide-VacationRentals)
-   [Isla Grande Vacation Rentals](https://expedia.ca/Isla-Grande-Vacation-Rentals.d6053183.Travel-Guide-VacationRentals)
-   [Hicaco Vacation Rentals](https://expedia.ca/Hicaco-Vacation-Rentals.d829298052413026304.Travel-Guide-VacationRentals)
-   [Penonome Vacation Rentals](https://expedia.ca/Penonome-Vacation-Rentals.d6058652.Travel-Guide-VacationRentals)
-   [Las Tablas Vacation Rentals](https://expedia.ca/Las-Tablas-Vacation-Rentals.d6347532.Travel-Guide-VacationRentals)
-   [Volcan Vacation Rentals](https://expedia.ca/Volcan-Vacation-Rentals.d6053182.Travel-Guide-VacationRentals)
-   [Alto Boquete Vacation Rentals](https://expedia.ca/Alto-Boquete-Vacation-Rentals.d6245664.Travel-Guide-VacationRentals)
-   [Las Lajas Vacation Rentals](https://expedia.ca/Las-Lajas-Vacation-Rentals.d553248623254974762.Travel-Guide-VacationRentals)
-   [Saboga Vacation Rentals](https://expedia.ca/Saboga-Vacation-Rentals.d829297425886765056.Travel-Guide-VacationRentals)
-   [Chiriqui Vacation Rentals](https://expedia.ca/Chiriqui-Vacation-Rentals.d6051578.Travel-Guide-VacationRentals)

-   [Apartments in Panama](https://expedia.ca/Panama-Apartments.d142-aaApartments.Travel-Guide-Accommodation)
-   [Vacation Homes in Panama](https://expedia.ca/Panama-Private-Vacation-Homes.d142-aaPrivateVacationHomes.Travel-Guide-Accommodation)
-   [Condo Rentals in Panama](https://expedia.ca/Panama-Condos.d142-aaCondos.Travel-Guide-Accommodation)
-   [B&B in Panama](https://expedia.ca/Panama-Bed-And-Breakfast.d142-aaBedAndBreakfast.Travel-Guide-Accommodation)
-   [Villas in Panama](https://expedia.ca/Panama-Villas.d142-aaVillas.Travel-Guide-Accommodation)
-   [Cabin Rentals in Panama](https://expedia.ca/Panama-Cabins.d142-aaCabins.Travel-Guide-Accommodation)
-   [Hostels in Panama](https://expedia.ca/Panama-Hostels.d142-aaHostels.Travel-Guide-Accommodation)
-   [Aparthotels in Panama](https://expedia.ca/Panama-Apart-Hotels.d142-aaApartHotels.Travel-Guide-Accommodation)
-   [Lodges in Panama](https://expedia.ca/Panama-Lodges.d142-aaLodges.Travel-Guide-Accommodation)
-   [Guest Houses in Panama](https://expedia.ca/Panama-Guest-Houses.d142-aaGuestHouses.Travel-Guide-Accommodation)
-   [Houseboats in Panama](https://expedia.ca/Panama-Houseboats.d142-aaHouseboats.Travel-Guide-Accommodation)
-   [Resorts in Panama](https://expedia.ca/Panama-Resort-Hotels.d142-aaResortHotels.Travel-Guide-Accommodation)
-   [Cottages in Panama](https://expedia.ca/Panama-Cottages.d142-aaCottages.Travel-Guide-Accommodation)
-   [Chalets in Panama](https://expedia.ca/Panama-Chalets.d142-aaChalets.Travel-Guide-Accommodation)
-   [Farmstay in Panama](https://expedia.ca/Panama-Agritourism.d142-aaAgritourism.Travel-Guide-Accommodation)
-   [Inns in Panama](https://expedia.ca/Panama-Inns.d142-aaInns.Travel-Guide-Accommodation)
-   [RV Parks in Panama](https://expedia.ca/Panama-RV-Parks.d142-aaRVParks.Travel-Guide-Accommodation)
-   [Condo Resorts in Panama](https://expedia.ca/Panama-Condominium-Resort.d142-aaCondominiumResort.Travel-Guide-Accommodation)
-   [Capsule Hotels in Panama](https://expedia.ca/Panama-Capsule-Hotels.d142-aaCapsuleHotels.Travel-Guide-Accommodation)
-   [Castles in Panama](https://expedia.ca/Panama-Castles.d142-aaCastles.Travel-Guide-Accommodation)

### Expedia's Latest Trends

Hotels

-   [All Inclusive Resorts and Hotels in Costa Rica](https://expedia.ca/Destinations-In-Costa-Rica-All-Inclusive-Hotel.0-0-d42-tAllInclusiveHotel.Hotel-Filter-Destinations)
-   [Hotels in Mexico](https://expedia.ca/Destinations-In-Mexico.d117.Hotel-Destinations)
-   [All Inclusive Resorts and Hotels in Mexico](https://expedia.ca/Destinations-In-Mexico-All-Inclusive-Hotel.0-0-d117-tAllInclusiveHotel.Hotel-Filter-Destinations)
-   [Family Hotels in Mexico](https://expedia.ca/Destinations-In-Mexico-Family-Hotel.0-0-d117-tFamilyHotel.Hotel-Filter-Destinations)
-   [Adults Only Resorts & Hotels in Mexico](https://expedia.ca/Destinations-In-Mexico-Adults-Only-Resorts.0-0-d117-tAdultsOnlyResorts.Hotel-Filter-Destinations)
-   [Waterpark Hotels in Mexico](https://expedia.ca/Destinations-In-Mexico-Waterpark-Hotels.0-0-d117-tWaterparkHotels.Hotel-Filter-Destinations)
-   [All Inclusive Resorts and Hotels in Guatemala](https://expedia.ca/Destinations-In-Guatemala-All-Inclusive-Hotel.0-0-d71-tAllInclusiveHotel.Hotel-Filter-Destinations)
-   [Golf Hotels in Mexico](https://expedia.ca/Destinations-In-Mexico-Golf-Hotel.0-0-d117-tGolfHotel.Hotel-Filter-Destinations)
-   [All Inclusive Resorts and Hotels in Belize](https://expedia.ca/Destinations-In-Belize-All-Inclusive-Hotel.0-0-d18-tAllInclusiveHotel.Hotel-Filter-Destinations)
-   [Hotels in Costa Rica](https://expedia.ca/Destinations-In-Costa-Rica.d42.Hotel-Destinations)
-   [All Inclusive Resorts and Hotels in Nicaragua](https://expedia.ca/Destinations-In-Nicaragua-All-Inclusive-Hotel.0-0-d134-tAllInclusiveHotel.Hotel-Filter-Destinations)
-   [All Inclusive Resorts and Hotels in El Salvador](https://expedia.ca/Destinations-In-El-Salvador-All-Inclusive-Hotel.0-0-d53-tAllInclusiveHotel.Hotel-Filter-Destinations)

Flights

-   [Flights to Nicaragua](https://expedia.ca/Destinations-In-Nicaragua.d134.Flight-Destinations)
-   [Flights to Costa Rica](https://expedia.ca/Destinations-In-Costa-Rica.d42.Flight-Destinations)
-   [Flights to El Salvador](https://expedia.ca/Destinations-In-El-Salvador.d53.Flight-Destinations)
-   [Flights to Mexico](https://expedia.ca/Destinations-In-Mexico.d117.Flight-Destinations)
-   [Flights to Belize](https://expedia.ca/Destinations-In-Belize.d18.Flight-Destinations)

Cars

-   [Car rentals in Costa Rica](https://expedia.ca/Destinations-In-Costa-Rica.d42.Car-Rental-Destinations)

Cruises

-   [Cruises to Mexico](https://expedia.ca/Cruises-to-Mexico.d117.Travel-Guide-Cruise)

Packages

-   [Costa Rica Vacations](https://expedia.ca/Costa-Rica.d42.Destination-Travel-Guides)
-   [Belize Vacations](https://expedia.ca/Belize.d18.Destination-Travel-Guides)
-   [Belize All-inclusive Vacation Packages](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations/18/Belize)
-   [Mexico All-inclusive Vacation Packages](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations/117/Mexico)
-   [Mexico All-inclusive Vacation Packages](https://expedia.ca/lp/theme-vacations/golf-vacations/117/Mexico)
-   [Nicaragua Vacations](https://expedia.ca/Nicaragua.d134.Destination-Travel-Guides)
-   [Mexico All-inclusive Vacation Packages](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations/117/Mexico)
-   [Mexico Vacations](https://expedia.ca/Mexico.d117.Destination-Travel-Guides)
-   [Costa Rica All-inclusive Vacation Packages](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations/42/Costa-Rica)
-   [El Salvador Vacations](https://expedia.ca/El-Salvador.d53.Destination-Travel-Guides)

General

-   [Visit Costa Rica](https://expedia.ca/Costa-Rica.dx42)