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Panama Vacation Rentals

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Top Vacation Rentals in in Panama

Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina, Panama City, Panama
The price is CA $66 per night from Oct 20 to Oct 21

Located in El Cangrejo, this hotel is within a 10-minute walk of Crown Casino and Via Espana. Uruguay Street and Avenida Balboa are also within 1 mile (2 km). ...

4.2/5Very Good! (415 reviews)

"Centrico y atentos. El acceso es muy bueno y el rest de sushi"…"

Reviewed on Aug. 17, 2020

Principe Hotel and Suites
Hyatt Place Panama City/Downtown

Hyatt Place Panama City/Downtown

3.5 out of 5
Avenida Aquilino de la Guardia, between, Vía España and Calle 52 Bella Vista, Panama City, Panama
The price is CA $75 per night from Nov 1 to Nov 2

Located in Campo Alegre, this hotel is within a 10-minute walk of Via Espana, Uruguay Street and Avenida Balboa. Cinta Costera and Multiplaza Pacific Mall are ...

4.3/5Excellent! (1,000 reviews)
Good location

"Hotel is a little worn but walking distance to restaurants. Has coin laundry on pool level which is great for multiweek travelers. Would.stay again."…"

Reviewed on Mar. 10, 2020

Hyatt Place Panama City/Downtown
Hilton Panama

Hilton Panama

5 out of 5
Balboa Ave. and Aquilino De La Guardia, Panama City, Panama
The price is CA $145 per night from Oct 24 to Oct 25

This family-friendly Panama City hotel is located in the business district, within 2 mi (3 km) of Multicentro Panama and Multiplaza Pacific Mall. Panama Viejo ...

4.4/5Excellent! (603 reviews)

"Great location and very clean. Confusing elevator system. Expensive drinks."…"

Reviewed on Apr. 1, 2020

Hilton Panama

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Bristol Panama

Bristol Panama

5 out of 5
Avenida Aquilino de La Guardia, Bella Vista, Panama City, Panama
The price is CA $250 per night from Nov 16 to Nov 17

Located in Campo Alegre, this luxury hotel is within a 10-minute walk of Via Espana and Avenida Balboa. Cinta Costera and Multiplaza Pacific Mall are also within ...

4.5/5Wonderful! (891 reviews)
Great stay

"Wonderful staff ! Beautiful property."…"

Reviewed on Feb. 29, 2020

Bristol Panama
Eurostars Panama City

Eurostars Panama City

4 out of 5
Calle Ricardo Arias, Bellavista Via Espana, Panama City, Panama

Located in Campo Alegre, this hotel is within a 10-minute walk of Via Espana and Uruguay Street. Avenida Balboa and Cinta Costera are also within 1 mile (2 km). ...

4.1/5Very Good! (997 reviews)

"Love the room and everything about Eurostars! Excellent professional staff, clean, over all excellent!"…"

Reviewed on May 12, 2020

Eurostars Panama City
Los Mandarinos Boutique Spa and Hotel

Los Mandarinos Boutique Spa and Hotel

4 out of 5
Calle Del Ciclo El Valle De Anton Cocle, El Valle de Anton, Cocle
The price is CA $223 per night from Oct 20 to Oct 21

This family-friendly El Valle de Anton hotel is located in the mountains, within a 10-minute walk of Sunday Market, El Nispero Zoo and Botanical Garden and APROVACA ...

4.1/5Very Good! (157 reviews)
Great stay at Los Mandarinos

"The hotel is comfortable and clean and the staff is friendly and helpful. It is set in the outskirts of the beautiful Valle de Anton. Furthermore it has good restaurants on the hotel area."…"

Reviewed on Mar. 22, 2020

Los Mandarinos Boutique Spa and Hotel
Dreams Playa Bonita Panama - Optional All Inclusive

Dreams Playa Bonita Panama - Optional All Inclusive

4 out of 5
KM 7, Road to Veracruz, Panama City, Panama

Located in Panama City, this beachfront resort is in a provincial park and within 6 mi (10 km) of Isla Taboga Pier, Veracruz Beach and Taboga Beach. Cinta Costera ...

3.8/5Good! (418 reviews)

"Staff was wonderful! Went out of their way to be helpful. Food was about what I expected at an All Inclusive (pretty good). Grounds were beautiful!"…"

Reviewed on Mar. 20, 2020

Dreams Playa Bonita Panama - Optional All Inclusive
Hard Rock Hotel Panama Megapolis

Hard Rock Hotel Panama Megapolis

4.5 out of 5
Ave. Balboa al lado de Multicentro, Panama City, Panama
The price is CA $152 per night from Nov 18 to Nov 19

This family-friendly Panama City hotel is located near the airport, just steps away from Avenida Balboa and Multicentro Panama. Multiplaza Pacific Mall and Via ...

4.2/5Very Good! (1,000 reviews)
One night stay

"Stay was good just one night"…"

Reviewed on Mar. 16, 2020

Hard Rock Hotel Panama Megapolis
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

4 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
The price is CA $131 per night from Nov 1 to Nov 2

Located in Campo Alegre, this eco-friendly hotel is within a 15-minute walk of Crown Casino and Fiesta Casino. Avenida Central and Museum of Natural Science ...

4.2/5Excellent! (1,000 reviews)

"Nice pool area with bar. Good food at bar restaurant. Concierge services and VIP assistance are impressive."…"

Reviewed on Mar. 12, 2020

Hotel Riu Plaza Panama
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You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Panama. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.