COVID-19 alert: Travel requirements are changing rapidly, including need for pre-travel COVID-19 testing and quarantine on arrival.

Panama Vacation Rentals

Search over 1 million properties and 550 airlines worldwide

Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.

Free cancellation on most hotels. Because flexibility matters.

Top Vacation Rentals in in Panama

Marriott Executive Apartments Panama City, Finisterre

Marriott Executive Apartments Panama City, Finisterre

4 out of 5
Calle Colombia Y Ave.,3ra A Sur, Bella V, Panama City, Panama
The price is CA $110 per night from Apr 23 to Apr 24
Located in Campo Alegre, this aparthotel is within a 10-minute walk of Iglesia del Carmen, Uruguay Street, and Avenida Balboa. Via Espana and Cinta Costera are ...
4.4/5Excellent! (321 reviews)
"Their COVID Process was rock star!! Special thanks to restaurant staff. Most them spoke English."

Reviewed on Apr. 3, 2021

Marriott Executive Apartments Panama City, Finisterre
Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites

3.5 out of 5
Calle Eusebio A. Morales y Calle 55, Panama City, Panama
The price is CA $108 per night from Apr 22 to Apr 23
Located in El Cangrejo, this aparthotel is within a 5-minute walk of Fiesta Casino and Via Espana. Uruguay Street and Avenida Balboa are also within 15 minutes. ...
4.3/5Excellent! (124 reviews)
"We stayed for five nights. The hotel is centrally located. Our unit is spacious, very bright and clean. We found our stay could be further improved with more cooking utensils in the kitchen and better staff communication in English."

Reviewed on Jan. 21, 2021

Torres de Alba Hotel & Suites
Tropical Beachfront Suite With Magnificent View

Tropical Beachfront Suite With Magnificent View

Las Lajas (Panama), Panamá Oeste Province
The price is CA $194 per night from Apr 23 to Apr 24
Situated in Playa Coronado, this condo building is 0.1 mi (0.1 km) from Coronado Beach and within 3 mi (5 km) of Teta Beach and Coronado Mall. Playa Malibú is ...
3/5 (1 review)
"Excellent views, pleasant room, clean. No amenities, had to ask several times for ice, scrounge for coffee. Would not stay here"

Reviewed on Apr. 4, 2019

Tropical Beachfront Suite With Magnificent View
You could be seeing lower prices

You could be seeing lower prices

With member prices, you could save 10% or more right now on thousands of properties.
Hacienda mi Montañita

Hacienda mi Montañita

3 out of 5
Calle Los Altos de Cerro Azul, El Portin, Cerro Azul, Panama
Situated in Cerro Azul, this vacation home is 0.1 mi (0.1 km) from Chagres National Park and within 25 mi (40 km) of Metromall Panama and Estadio Rommel Fernandez. ...
3.5/5Good! (4 reviews)
"This was a beautiful property when it comes to been in the clouds and as close to nature as possible. The wind is loud at nighttime and whistles through the house all night; making it difficult to sleep. I booked through Expedia and the owner said she did not receive my reservation. I had made this ..."

Reviewed on Jan. 9, 2019

Hacienda mi Montañita
Bocas Villas - Private Acqua Villas

Bocas Villas - Private Acqua Villas

Bocas del Toro, Bocas del Toro (province)
Situated by the ocean, this vacation home is within a 15-minute walk of Playa Punch, Carenero Island, and La Gruta Cave. Hospital Point and Bastimento-Bocas ...
4.7/5Exceptional! (18 reviews)
Wonderful stay among the sloths, sting rays and pelicans!
"We had such a great stay at the Bocas Villas! My husband and I spent a week of our honeymoon there and it was absolutely beautiful. Kris and Faubion (the on-site managers of the property) made our stay even more special by welcoming us and being open to every question and/or request. The location ..."

Reviewed on Jan. 31, 2020

Bocas Villas - Private Acqua Villas
Enchanting Villa in Coronado With Wifi

Enchanting Villa in Coronado With Wifi

Nueva Gorgona, Panamá Oeste Province
The price is CA $107 per night from May 4 to May 5
Situated near the beach, this vacation home is 1.3 mi (2.1 km) from Coronado Beach and 3 mi (4.8 km) from Teta Beach. Coronado Mall and Playa Malibú are also ...
Enchanting Villa in Coronado With Wifi
Las Clementinas

Las Clementinas

3.5 out of 5
Casco Antiguo, Calle 11 Y Ave B, Panama City, Panama
Located in Casco Viejo, this aparthotel is within a 10-minute walk of Amador Theater and Avenida Balboa. Albrook Shopping Mall and Cinta Costera are also within ...
4.5/5Wonderful! (93 reviews)
"The personnel was top notch, dedicated to pleasing our every need."

Reviewed on Mar. 2, 2020

Las Clementinas
Bocas Lofts

Bocas Lofts

3 out of 5
Close by the gas station out of town, Bocas del Toro, Bocas del Toro
The price is CA $112 per night from Apr 22 to Apr 23
Located in Saigon, this beach apartment building is within a 15-minute walk of Playa El Istmito and Finca Los Monos Botanical Garden. Bocas Butterfly Garden ...
5/5Exceptional! (2 reviews)
Super comfort in a great location
"Amazing place in a perfect location. The loft is quite large especially having such high ceilings. The bed is a king and is really comfortable. The big surprise was the kitchenette which was not listed. It has a fridge an induction hot plate with some pots and dishes. There is a coffee maker and ..."

Reviewed on Feb. 21, 2020

Bocas Lofts
Hermosa Y Comoda Casa EN LAS Costas DEL MAR Caribe IN Front OF THE SEA

Hermosa Y Comoda Casa EN LAS Costas DEL MAR Caribe IN Front OF THE SEA

Portobelo, Colon
The price is CA $315 per night from May 11 to May 12
Situated in Portobelo, this historic vacation home is 0.1 mi (0.1 km) from Portobelo National Park and within 3 mi (5 km) of Fuerte Santiago and Fuerte San Fernando. ...
3.5/5Good! (2 reviews)
Wonderful!
"What a fantastic property! You could not ask for more if you plan to stay on the Caribbean side of Panama... Casa Buenaventura was perfect for our troop of 4 adults and 5 children. Clean, well appointed, lots of space... and Gabriel was the best! He met us personally upon check in to show the house, ..."

Reviewed on Aug. 10, 2019

Hermosa Y Comoda Casa EN LAS Costas DEL MAR Caribe IN Front OF THE SEA
Beautiful Beach House With Private Pool

Beautiful Beach House With Private Pool

Nueva Gorgona, Panamá Oeste Province
Situated in Nueva Gorgona, this vacation home is within 3 mi (5 km) of Coronado Beach, Coronado Mall, and Teta Beach. Playa Malibú and Playa El Palmar are also ...
Beautiful Beach House With Private Pool
Beautiful Villa in Buenaventura

Beautiful Villa in Buenaventura

El Chiru, Cocle
The price is CA $1,190 per night from May 17 to May 18
Situated in El Chiru, this vacation home is 1.9 mi (3 km) from Playa Blanca and within 6 mi (10 km) of Farallon Beach and Parroquia Santiago Apóstol de Río Hato. ...
Beautiful Villa in Buenaventura
Cabañita El Cedro - Rustic and Comfortable 200 Meters From the Main Road - Volcan

Cabañita El Cedro - Rustic and Comfortable 200 Meters From the Main Road - Volcan

Volcan, Chiriqui (province)
The price is CA $63 per night from Apr 22 to Apr 23
Situated in Volcan, this vacation home is 7.3 mi (11.8 km) from Sitio Barriles Museum.
Cabañita El Cedro - Rustic and Comfortable 200 Meters From the Main Road - Volcan
Beautiful House in the Mountains in a Peaceful Area of Boquete

Beautiful House in the Mountains in a Peaceful Area of Boquete

Boquete, Chiriqui (province)
The price is CA $441 per night from Apr 23 to Apr 24
Situated in Boquete, this vacation home is within 3 mi (5 km) of Boquete Library, Boquete Community Players Theater and Events Center, and Municipal Park. Church ...
Beautiful House in the Mountains in a Peaceful Area of Boquete
Luxury Apartment in Playa Bonita, 10 Minutes From Panama City

Luxury Apartment in Playa Bonita, 10 Minutes From Panama City

Panama City, Panamá Oeste Province
Located in Panama City, this beachfront condo building is in the city center and within 6 mi (10 km) of Isla Taboga Pier, Veracruz Beach, and Bridge of the Americas. ...
4.5/5Wonderful! (31 reviews)
"It was clean and quite. It would be nice to have an open pantry (take and replace) for basic food things like sugar, margarine, coffee, dishwasher detergent etc."

Reviewed on Mar. 5, 2020

Luxury Apartment in Playa Bonita, 10 Minutes From Panama City
Luxury Beach Front Apartment in Playa Bonita, 10 Minutes From Panama City

Luxury Beach Front Apartment in Playa Bonita, 10 Minutes From Panama City

Panama City, Panamá Oeste Province
Located in Panama City, this beachfront condo building is in the city center and within 6 mi (10 km) of Isla Taboga Pier, Veracruz Beach, and Bridge of the Americas. ...
4.8/5Exceptional! (6 reviews)
Canadians in Panama 16nts Jan2020
"Remi and Ana are fantastic hosts. The condo was modern, clean, and very comfortable. They were quick to respond with any questions we had which as you know, provides a feeling of security and comfort. Overall the building was a pleasure to stay in, we rented a car during our stay and had no issues ..."

Reviewed on Feb. 6, 2020

Luxury Beach Front Apartment in Playa Bonita, 10 Minutes From Panama City
Playa Morrillo Torio Mariato Beachfront

Playa Morrillo Torio Mariato Beachfront

Torio, Veraguas
The price is CA $74 per night from Apr 27 to Apr 28
Situated in Torio, this vacation home is 0.1 mi (0.1 km) from Peninsula de Azuero and 2 mi (3.3 km) from Duarte Point. Torio Beach is 5.3 mi (8.6 km) away.
Playa Morrillo Torio Mariato Beachfront
Beautiful Homes Spectacular Pool/gym

Beautiful Homes Spectacular Pool/gym

Chame, Panamá Oeste Province
The price is CA $150 per night from Apr 22 to Apr 23
Situated by the ocean, this vacation home is within 12 mi (20 km) of Coronado Mall, Playa Malibú, and Teta Beach. Coronado Beach and Los Cajones de Chame are ...
4/5Very Good! (3 reviews)
Winter holiday
"The so call resort was very boring not many people there the people that where left early as we did we left a month early. Would not recommend this property."

Reviewed on Mar. 16, 2020

Beautiful Homes Spectacular Pool/gym
Country House in La Laguna de San Carlos Panama

Country House in La Laguna de San Carlos Panama

panama, panama
The price is CA $88 per night from Apr 25 to Apr 26
Situated in Panama City, this vacation home is within a 10-minute walk of Iglesia del Carmen, Via Espana, and Uruguay Street. Avenida Balboa and Cinta Costera ...
Country House in La Laguna de San Carlos Panama
Luxury Penthouse 5 Bedroom Beach Condo

Luxury Penthouse 5 Bedroom Beach Condo

San Jose, Panamá Oeste Province
Situated on the beach, this romantic resort is 0.9 mi (1.5 km) from Coronado Mall and 1.4 mi (2.3 km) from Teta Beach. Coronado Beach and Playa Malibú are also ...
Luxury Penthouse 5 Bedroom Beach Condo
Family Beach House! Walk to Beach/surf. Costa Esmeralda, San Carlos

Family Beach House! Walk to Beach/surf. Costa Esmeralda, San Carlos

San Carlos, Panamá Oeste Province
Situated in San Carlos, this vacation home is within 9 mi (15 km) of Coronado Mall, Teta Beach, and Coronado Beach. Playa El Palmar and Playa Malibú are also ...
4.7/5Exceptional! (3 reviews)
Great Family Holiday Home
"Our family immensely enjoyed our very short stay at the casa; in every way it was perfect for us!"

Reviewed on Dec. 27, 2019

Family Beach House! Walk to Beach/surf. Costa Esmeralda, San Carlos
Don't see what you're looking for?
See all available properties in Panama
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Panama. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Top Cities in Panama