Title: Panama City Vacation Rentals from CA $106: Short-Term Rentals for 2026 | Expedia.ca

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![Panoramic view at the Downtown of Panama City - Panama](https://images.trvl-media.com/place/2897/e48f6143-9130-47fe-8b71-977ffb07b927.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/2897/e48f6143-9130-47fe-8b71-977ffb07b927.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2026-02-13&endDate=2026-02-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2026-03-27&endDate=2026-03-29&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Apr 24 - Apr 26](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2026-04-24&endDate=2026-04-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[May 22 - May 24](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Panama City vacation rentals

![Interior detail](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/2453d7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Double Room | View from room](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/c6d0b885.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite, Annex Building (Queen) | Living area](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/f680e3a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite, Annex Building (King) | Living area](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/6f5654fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Isabela Suites

[](https://www.expedia.ca/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information)

Casco Viejo

10/10

Exceptional

(175 reviews)

"Excellent place to stay in the Casco Viejo "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Zoe M

[](https://www.expedia.ca/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/1012405e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Apartment | View from room](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/1b369fc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sundeck](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/03c049bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite, 2 Double Beds | Living area](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/871ef81e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Torres de Alba Hotel & Suites

[](https://www.expedia.ca/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information)

Bella Vista

8.8/10

Excellent

(506 reviews)

"Excellent place, friendly staff, great breakfast and many shops close by. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Raymond

CA $126

CA $138 total

includes taxes & fees

Jan 30 - Jan 31

[](https://www.expedia.ca/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/24a7280d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/765b1a36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/2370102e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio, 2 Double Beds, Non Smoking, Connecting Rooms](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/da2b9bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Las Clementinas

[](https://www.expedia.ca/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information)

Casco Viejo

9.4/10

Exceptional

(174 reviews)

"Fabulous room and wonderful people that work there. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Leah

CA $236

CA $260 total

includes taxes & fees

Feb 1 - Feb 2

[](https://www.expedia.ca/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/94d2f2bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, City View | Interior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/7c635746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![15 outdoor pools](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/bee413e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, City View | Interior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/600a3940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Luxury Apartment Piso 35 with City View

[](https://www.expedia.ca/Panama-City-Hotels-Luxury-Apartment-Piso-35-With-City-View.h125266330.Hotel-Information)

Bella Vista

CA $97

CA $106 total

includes taxes & fees

Feb 10 - Feb 11

[](https://www.expedia.ca/Panama-City-Hotels-Luxury-Apartment-Piso-35-With-City-View.h125266330.Hotel-Information)

![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/bba49e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining room](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfbf214.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/f23a333a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Arcadia Condo Suites

[](https://www.expedia.ca/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information)

Costa del Este

9.2/10

Wonderful

(200 reviews)

"Excellent space, great layout, friendly staff, responsive staff. Will stay there again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nick

CA $113

CA $244 total

includes taxes & fees

Mar 1 - Mar 2

[](https://www.expedia.ca/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/115000000/114940000/114936500/114936429/b4a0c18f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Apartment](https://images.trvl-media.com/lodging/115000000/114940000/114936500/114936429/e60fdc50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment | Living area](https://images.trvl-media.com/lodging/115000000/114940000/114936500/114936429/adb5e592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment | Living area](https://images.trvl-media.com/lodging/115000000/114940000/114936500/114936429/96c7a350.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Sands by Wynwood House

[](https://www.expedia.ca/Panama-City-Hotels-The-Sands-By-Wynwood-House.h114936429.Hotel-Information)

Calidonia

CA $164

CA $217 total

includes taxes & fees

Feb 3 - Feb 4

[](https://www.expedia.ca/Panama-City-Hotels-The-Sands-By-Wynwood-House.h114936429.Hotel-Information)

![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/c0e07415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/601ad506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/4d9b3d57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/375f6530.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Centriqo by Wynwood house 

[](https://www.expedia.ca/Veracruz-Hotels-Centriqo-By-Wynwood-House.h113058427.Hotel-Information)

Veracruz

CA $173

CA $235 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Veracruz-Hotels-Centriqo-By-Wynwood-House.h113058427.Hotel-Information)

![Apartment](https://images.trvl-media.com/lodging/120000000/119090000/119080400/119080389/24132540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment](https://images.trvl-media.com/lodging/120000000/119090000/119080400/119080389/67621525.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment](https://images.trvl-media.com/lodging/120000000/119090000/119080400/119080389/0982ec7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment](https://images.trvl-media.com/lodging/120000000/119090000/119080400/119080389/80c46482.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### w Homely 2BR With Balcony in Panama

[](https://www.expedia.ca/Panama-City-Hotels-W-Homely-2BR-With-Balcony-In-Panama.h119080389.Hotel-Information)

Casco Viejo

CA $166

CA $260 total

includes taxes & fees

Feb 1 - Feb 2

[](https://www.expedia.ca/Panama-City-Hotels-W-Homely-2BR-With-Balcony-In-Panama.h119080389.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/115000000/114590000/114580500/114580453/46eb55a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/115000000/114590000/114580500/114580453/3b2566fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment](https://images.trvl-media.com/lodging/115000000/114590000/114580500/114580453/9c70698c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/115000000/114590000/114580500/114580453/267d4c66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wanders Panama by Boutique Apartments

[](https://www.expedia.ca/Wanders-Panama-By-Boutique-Apartments.h114580453.Hotel-Information)

San Francisco

10/10

Exceptional

(2 reviews)

"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gary

CA $211

CA $439 total

includes taxes & fees

Feb 1 - Feb 2

[](https://www.expedia.ca/Wanders-Panama-By-Boutique-Apartments.h114580453.Hotel-Information)

![Deluxe Apartment | Living area](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/0a2a9e4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Apartment | Balcony](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/3c59dc38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Apartment | Living area](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/6f82906f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Apartment | Living area](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/97957e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Moderna by Wynwood House

[](https://www.expedia.ca/Panama-City-Hotels-La-Moderna-By-Wynwood-House.h100587737.Hotel-Information)

Casco Viejo

7.4/10

Good

(44 reviews)

"The nightlife around there was incredible"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Felix

CA $112

CA $168 total

includes taxes & fees

Feb 5 - Feb 6

[](https://www.expedia.ca/Panama-City-Hotels-La-Moderna-By-Wynwood-House.h100587737.Hotel-Information)

![Outdoor pool, free cabanas, sun loungers](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/a1255d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Apartment | Private kitchen](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/6e3eaaf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exclusive Apartment | Living area](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/9a282904.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Apartment | View from room](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/3a0adaf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Yoo Panama & Arts Tower

[](https://www.expedia.ca/Panama-City-Hotels-Apto-35G-Vista-A-La-Ciudad.h83067546.Hotel-Information)

Bella Vista

9.6/10

Exceptional

(64 reviews)

"Beautiful apartment. Great viiew of the bay from balcony. Food and shopping options within walking distance. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sharon

CA $197

CA $300 total

includes taxes & fees

Mar 1 - Mar 2

[](https://www.expedia.ca/Panama-City-Hotels-Apto-35G-Vista-A-La-Ciudad.h83067546.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/123000000/122130000/122120100/122120019/6dbcedff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop terrace](https://images.trvl-media.com/lodging/123000000/122130000/122120100/122120019/fb6b983e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Studio, Sea View](https://images.trvl-media.com/lodging/123000000/122130000/122120100/122120019/9e72b36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Studio, Sea View | Balcony view](https://images.trvl-media.com/lodging/123000000/122130000/122120100/122120019/cf68e67c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Studio Apartment with Ocean View

[](https://www.expedia.ca/Panama-City-Hotels-Studio-Apartment-With-Ocean-View.h122120019.Hotel-Information)

Calidonia

8.0/10

Very good

(2 reviews)

"It was similar to a hotel room, but a little smaller.. the bed is big enough for just one person and check in was the most difficult thing he had to wait outside in the rain and download apps"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gwendolyn

CA $88

CA $97 total

includes taxes & fees

Feb 1 - Feb 2

[](https://www.expedia.ca/Panama-City-Hotels-Studio-Apartment-With-Ocean-View.h122120019.Hotel-Information)

![Apartment, 2 Bedrooms (1A) | Living area](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/42608a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2A) | Living area](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/fc090f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2A)](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/9a31f88b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 2 Bedrooms (1A) | Living area](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/0447e43a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Lefevre By Wynwood House

[](https://www.expedia.ca/Las-Cumbres-Hotels-Casa-Lefevre-By-Wynwood-House.h104134950.Hotel-Information)

Casco Viejo

9.2/10

Wonderful

(5 reviews)

"Staff was courteous, and the room was very beautiful. Would stay here again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Selam

CA $208

CA $266 total

includes taxes & fees

Feb 2 - Feb 3

[](https://www.expedia.ca/Las-Cumbres-Hotels-Casa-Lefevre-By-Wynwood-House.h104134950.Hotel-Information)

![Apartment (14D) | Dining room](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/2a0412bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (5E) | Living area](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/e5dc9f9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (11F) | Living area](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/3115996f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (14D)](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/422dd5ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mini Design By Wynwood House

[](https://www.expedia.ca/Panama-City-Hotels-Mini-Design-By-Wynwood-House.h117462452.Hotel-Information)

Bella Vista

CA $158

CA $212 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Panama-City-Hotels-Mini-Design-By-Wynwood-House.h117462452.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/123000000/122660000/122657100/122657050/87d5a99d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment | Balcony](https://images.trvl-media.com/lodging/123000000/122660000/122657100/122657050/618d23dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/123000000/122660000/122657100/122657050/be270857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Gym](https://images.trvl-media.com/lodging/123000000/122660000/122657100/122657050/1cbda3e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Living 73 Panamá by Boutique Apartments

[](https://www.expedia.ca/Panama-City-Hotels-Living-73.h122657050.Hotel-Information)

San Francisco

CA $54

CA $259 total

includes taxes & fees

Feb 2 - Feb 3

[](https://www.expedia.ca/Panama-City-Hotels-Living-73.h122657050.Hotel-Information)

![Apartment, 3 Bedrooms, Accessible, Pool View | Pool](https://images.trvl-media.com/lodging/120000000/119470000/119462200/119462129/76eefaf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 3 Bedrooms, Accessible, Pool View | Interior](https://images.trvl-media.com/lodging/120000000/119470000/119462200/119462129/5864a396.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room amenity](https://images.trvl-media.com/lodging/120000000/119470000/119462200/119462129/3979bb6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 3 Bedrooms, Accessible, Pool View](https://images.trvl-media.com/lodging/120000000/119470000/119462200/119462129/094709c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 3 Bedroom Apartment in San Miguelito, Panama City

[](https://www.expedia.ca/San-Miguelito-Hotels-Apto-3-Hab-Piscina-15-Tocumen-Min-Airport.h119462129.Hotel-Information)

José Domingo Espinar

CA $99

CA $150 total

includes taxes & fees

Feb 5 - Feb 6

[](https://www.expedia.ca/San-Miguelito-Hotels-Apto-3-Hab-Piscina-15-Tocumen-Min-Airport.h119462129.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/7731b155.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/16f7b9a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room dining](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/5ace70c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch TV with cable channels](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/24c4ebfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Yoo Apartamento 

[](https://www.expedia.ca/Panama-City-Hotels-Yoo-Apartamento.h94627351.Hotel-Information)

Bella Vista

9.6/10

Exceptional

(14 reviews)

"Great location"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jimmy Lee

CA $119

CA $191 total

includes taxes & fees

Feb 23 - Feb 24

[](https://www.expedia.ca/Panama-City-Hotels-Yoo-Apartamento.h94627351.Hotel-Information)

![Apartment](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391242/9f6bde45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391242/046bf4b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391242/bfa00ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391242/b407ee76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfortable 2BR City Apartment

[](https://www.expedia.ca/Panama-City-Hotels-Comfortable-2BR-City-Apartment.h123391242.Hotel-Information)

San Francisco

CA $276

CA $303 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Panama-City-Hotels-Comfortable-2BR-City-Apartment.h123391242.Hotel-Information)

![An infinity pool](https://images.trvl-media.com/lodging/79000000/78610000/78605500/78605497/172b71e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/79000000/78610000/78605500/78605497/0c821668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/79000000/78610000/78605500/78605497/cffde6ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/79000000/78610000/78605500/78605497/593a0532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beutiful Apartment, High Speed Internet, Excellent Location

[](https://www.expedia.ca/Panama-City-Hotels-Beutiful-Apartment.h78605497.Hotel-Information)

San Francisco

8.8/10

Excellent

(14 reviews)

"It could use a few lamps especially in the bedroom, some pictures on the walls. The curtains in the smaller bedroom didn’t close on the right side. It’s a bit run down for the price. The location is ok. It is in a neighborhood so must take a taxi. That was ok as taxis are everywhere. The view of the water is great as it has almost wrap around windows in the living/ social area."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Teri

CA $127

CA $194 total

includes taxes & fees

Feb 5 - Feb 6

[](https://www.expedia.ca/Panama-City-Hotels-Beutiful-Apartment.h78605497.Hotel-Information)

![Apartment, 3 Bedrooms (4B) | Living area](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/edb72763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 3 Bedrooms (4B) | Living area](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/17257b2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 2 Bedrooms (2C) | Balcony](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/273fe814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (3B)](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/3372238d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Donovan By Wynwood House 

[](https://www.expedia.ca/Panama-City-Hotels-Donovan-By-Wynwood-House.h100638302.Hotel-Information)

Casco Viejo

8.4/10

Very good

(47 reviews)

"I always love to stay at Wynwood properties in Panama "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alberto B

CA $111

CA $163 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Panama-City-Hotels-Donovan-By-Wynwood-House.h100638302.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-12&endDate=2026-02-13&regionId=2897&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Apartments

[](https://www.expedia.ca/Hotel-Search?destination=Panama+City%2C+Panam%C3%A1+Province%2C+Panama&regionId=2897&latLong=8.98144%2C-79.525482&adults=2&startDate=2026-04-29&d1=2026-04-29&endDate=2026-05-02&d2=2026-05-02&lodging=APARTMENT)

Aparthotels

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Condos

[](https://www.expedia.ca/Hotel-Search?destination=Panama+City%2C+Panam%C3%A1+Province%2C+Panama&regionId=2897&latLong=8.98144%2C-79.525482&adults=2&startDate=2026-04-29&d1=2026-04-29&endDate=2026-05-02&d2=2026-05-02&lodging=CONDO)

Private vacation homes

[](https://www.expedia.ca/Hotel-Search?destination=Panama+City%2C+Panam%C3%A1+Province%2C+Panama&regionId=2897&latLong=8.98144%2C-79.525482&adults=2&startDate=2026-04-29&d1=2026-04-29&endDate=2026-05-02&d2=2026-05-02&lodging=VACATION_HOME)

Villas

[](https://www.expedia.ca/Hotel-Search?destination=Panama+City%2C+Panam%C3%A1+Province%2C+Panama&regionId=2897&latLong=8.98144%2C-79.525482&adults=2&startDate=2026-04-29&d1=2026-04-29&endDate=2026-05-02&d2=2026-05-02&lodging=VILLA)

Houseboats

[](https://www.expedia.ca/Hotel-Search?destination=Panama+City%2C+Panam%C3%A1+Province%2C+Panama&regionId=2897&latLong=8.98144%2C-79.525482&adults=2&startDate=2026-04-29&d1=2026-04-29&endDate=2026-05-02&d2=2026-05-02&lodging=HOUSE_BOAT)

Cabins

[](https://www.expedia.ca/Hotel-Search?destination=Panama+City%2C+Panam%C3%A1+Province%2C+Panama&regionId=2897&latLong=8.98144%2C-79.525482&adults=2&startDate=2026-04-29&d1=2026-04-29&endDate=2026-05-02&d2=2026-05-02&lodging=CABIN)

Cottages

[](https://www.expedia.ca/Hotel-Search?destination=Panama+City%2C+Panam%C3%A1+Province%2C+Panama&regionId=2897&latLong=8.98144%2C-79.525482&adults=2&startDate=2026-04-29&d1=2026-04-29&endDate=2026-05-02&d2=2026-05-02&lodging=COTTAGE)

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## Top Panama City Hotel Reviews

![Decapolis Hotel Panama City](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg)

### Decapolis Hotel Panama City

10/10 Excellent

"Great staff. Room, amenties, and clean room."

[](https://expedia.ca/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information)

![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg)

### Plaza Paitilla Inn Hotel

10/10 Excellent

"staff was excellent"

[](https://expedia.ca/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information)

![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg)

### The Executive Hotel

10/10 Excellent

"Room was clean, beds were very comfortable, staff was excellent"

[](https://expedia.ca/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information)

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg)

### Hotel Riu Plaza Panama

10/10 Excellent

"Great"

[](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information)

![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg)

### Waymore Hotel Spa & Casino

10/10 Excellent

"Nice stay. Casino was fun with big TVs to watch games, food was decent with nice accommodations. I would stay again. "

[](https://expedia.ca/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information)

![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg)

### W Panama

10/10 Excellent

"Second time staying and it was flawless."

[](https://expedia.ca/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg)

### Marriott Panama Hotel

10/10 Excellent

"Very good"

[](https://expedia.ca/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information)

![Novotel Panama City](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/aad97f9d_y.jpg)

### Novotel Panama City

10/10 Excellent

"Clean room nice curtains kind staff one thing that could improve is the breakfast needs more choices "

[](https://expedia.ca/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information)

![Ramada Plaza by Wyndham Panama Punta Pacifica](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/803aefa9_y.jpg)

### Ramada Plaza by Wyndham Panama Punta Pacifica

10/10 Excellent

"Very clean. Staff was helpful."

[](https://expedia.ca/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information)

## Find out more about Panama City

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.  
  
As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Panama City. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.   
  
It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.   

## Explore a world of travel with Expedia

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- [British Columbia Vacation Rentals ](https://www.expedia.ca/Destinations-In-British-Columbia.d11117.Vacation-Rental-Destinations)
- [Prince Edward Island Vacation Rentals ](https://www.expedia.ca/Destinations-In-Prince-Edward-Island.d6058122.Vacation-Rental-Destinations)
- [Québec Vacation Rentals ](https://www.expedia.ca/Quebec-Vacation-Rentals.d180017.Travel-Guide-VacationRentals)

- [Apartments in Panama City ](https://expedia.ca/Panama-City-Apartments.d2897-aaApartments.Travel-Guide-Accommodation)
- [Condo Rentals in Panama City ](https://expedia.ca/Panama-City-Condos.d2897-aaCondos.Travel-Guide-Accommodation)
- [Vacation Homes in Panama City ](https://expedia.ca/Panama-City-Private-Vacation-Homes.d2897-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [B&B in Panama City ](https://expedia.ca/Panama-City-Bed-And-Breakfast.d2897-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Hostels in Panama City ](https://expedia.ca/Panama-City-Hostels.d2897-aaHostels.Travel-Guide-Accommodation)
- [Aparthotels in Panama City ](https://expedia.ca/Panama-City-Apart-Hotels.d2897-aaApartHotels.Travel-Guide-Accommodation)
- [Guest Houses in Panama City ](https://expedia.ca/Panama-City-Guest-Houses.d2897-aaGuestHouses.Travel-Guide-Accommodation)
- [Cottages in Panama City ](https://expedia.ca/Panama-City-Cottages.d2897-aaCottages.Travel-Guide-Accommodation)
- [Lodges in Panama City ](https://expedia.ca/Panama-City-Lodges.d2897-aaLodges.Travel-Guide-Accommodation)
- [Resorts in Panama City ](https://expedia.ca/Panama-City-Resort-Hotels.d2897-aaResortHotels.Travel-Guide-Accommodation)
- [Chalets in Panama City ](https://expedia.ca/Panama-City-Chalets.d2897-aaChalets.Travel-Guide-Accommodation)
- [Houseboats in Panama City ](https://expedia.ca/Panama-City-Houseboats.d2897-aaHouseboats.Travel-Guide-Accommodation)

## Frequently asked questions

### Can I find vacation rentals in Panama City?

### What's the top vacation rental in Panama City?

> Discover our completely remodeled home in Casco Viejo, perfect for up to 12 guests. Relax by the pool, enjoy the rooftop jacuzzi and BBQ, and experience modern comfort blended with hi](https://www.expedia.ca/Panama-City-Hotels-Charming-Maison-4Bdr-4Bth-In-Historic-Center-Of-Casco-Viejo.h101867438.Hotel-Information).

### How many vacation rentals are there in Panama City?

### What can I see and do in Panama City?

### What are vacation rentals like in Panama City?

### Expedia's Latest Trends

Hotels

- [Best Hotels in Boquete](https://expedia.ca/Boquete-Hotels.d500194.Travel-Guide-Hotels)
- [Hotels in Casco Viejo](https://expedia.ca/Casco-Viejo-Panama-City-Hotels.0-n6285189-0.Travel-Guide-Filter-Hotels)
- [Best Hotels in Bocas del Toro](https://expedia.ca/Bocas-Del-Toro-Hotels.d6023445.Travel-Guide-Hotels)
- [Hotels in Punta Paitilla](https://expedia.ca/Punta-Paitilla-Panama-City-Hotels.0-n6285983-0.Travel-Guide-Filter-Hotels)
- [Avenida Balboa hotels](https://expedia.ca/Avenida-Balboa-Hotels.0-l553248623453290531-0.Travel-Guide-Filter-Hotels)

Flights

- [Flights to Panama City](https://expedia.ca/Cheap-Flights-To-Marcos-A-Gelabert-Intl.d4407632.Travel-Guide-Flights)
- [Flights to Colon](https://expedia.ca/Cheap-Flights-To-Colon.d601867.Travel-Guide-Flights)
- [Flights to Chepo](https://expedia.ca/Cheap-Flights-To-Chepo.d553248622834396118.Travel-Guide-Flights)
- [Flights to Rio Hato](https://expedia.ca/Cheap-Flights-To-Rio-Hato.d6246042.Travel-Guide-Flights)
- [Flights to Bocas del Toro](https://expedia.ca/Cheap-Flights-To-Bocas-Del-Toro.d6023445.Travel-Guide-Flights)

Cars

- [Car rentals in Rio Hato](https://expedia.ca/Car-Rentals-In-Rio-Hato.d6246042.Car-Rental-Guide)

Activities

- [Things to do in Bocas del Toro](https://expedia.ca/Things-To-Do-In-Bocas-Del-Toro.d6023445.Travel-Guide-Activities)
- [Things to do in Penonome](https://expedia.ca/Things-To-Do-In-Penonome.d6058652.Travel-Guide-Activities)
- [Things to do in Rio Hato](https://expedia.ca/Things-To-Do-In-Rio-Hato.d6246042.Travel-Guide-Activities)
- [Things to do in Tocumen](https://expedia.ca/Things-To-Do-In-Tocumen.d6053184.Travel-Guide-Activities)

Packages

- [Bocas del Toro Trip](https://expedia.ca/Bocas-Del-Toro.d6023445.Destination-Travel-Guides)
- [Rio Hato Trip](https://expedia.ca/Rio-Hato.d6246042.Destination-Travel-Guides)

Vacation Rentals

- [Rentals in Boquete](https://expedia.ca/Boquete-Vacation-Rentals.d500194.Travel-Guide-VacationRentals)
- [Rentals in Bocas del Toro](https://expedia.ca/Bocas-Del-Toro-Vacation-Rentals.d6023445.Travel-Guide-VacationRentals)

General

- [Visit Boquete](https://expedia.ca/Boquete.dx500194)
- [Visit Bella Vista](https://expedia.ca/Panama-City-Bella-Vista.dx3000663485)
- [Visit Casco Viejo](https://expedia.ca/Panama-City-Casco-Viejo.dx6285189)
- [Visit El Valle de Anton](https://expedia.ca/El-Valle-De-Anton.dx6053180)
- [Visit Campo Alegre](https://expedia.ca/Panama-City-Campo-Alegre.dx553248635976397615)
- [Visit Rio Hato](https://expedia.ca/Rio-Hato.dx6246042)
- [Visit Costa del Este](https://expedia.ca/Panama-City-Costa-Del-Este.dx3000663480)
- [Visit Pacora](https://expedia.ca/Pacora.dx705719212110229504)
- [Visit Punta Pacifica](https://expedia.ca/Panama-City-Punta-Pacifica.dx3000663482)
- [Visit Calidonia](https://expedia.ca/Panama-City-Calidonia.dx3000663488)
- [Visit Parque Lefevre](https://expedia.ca/Panama-City-Parque-Lefevre.dx553248623199116155)

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