Panama City Vacation Rentals

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Our top choices for Panama City vacation rentals

Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (545 reviews)
"Breakfast was one of the best ive been to"
United States
Tron
The price is CA $158
CA $174 total
includes taxes & fees
May 2 - May 3
Torres de Alba Hotel & Suites

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (279 reviews)
"Very good place to stay and safe place..!"
United States
Somnueg
The price is CA $164
CA $244 total
includes taxes & fees
May 3 - May 4
Arcadia Condo Suites

Boutique Apartments Panama

Boutique Apartments Panama
3.5 star property
Bella Vista
7.8 out of 10, Good, (283 reviews)
"Inhouse laundry service was very useful. Shops and restaurants nearby."
United States
Dustin
The price is CA $48
CA $203 total
includes taxes & fees
May 3 - May 4
Boutique Apartments Panama

Marriott Executive Apartments Panama City, Finisterre

Marriott Executive Apartments Panama City, Finisterre
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (710 reviews)
"Nice location and good for families with children "
United States
Ahsan
The price is CA $185
CA $203 total
includes taxes & fees
May 14 - May 15
Marriott Executive Apartments Panama City, Finisterre

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.4 out of 10, Good, (189 reviews)
"Nice place, convenient and nicely priced"
United States
Camille L
The price is CA $68
CA $266 total
includes taxes & fees
May 12 - May 13
Boutique Apartments Panamá Coco del Mar

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
3.5 star property
San Francisco
7.6 out of 10, Good, (10 reviews)
"Amazing! Great staff and wonderful high top views. "
United States
Krysta Alicia
The price is CA $176
CA $194 total
includes taxes & fees
May 3 - May 4
Dovle Residences by HMS-Preferred Member

Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.0 out of 10, Very good, (93 reviews)
"Friendly staff "
United States
Charles
The price is CA $88
CA $287 total
includes taxes & fees
May 12 - May 13
Yoo Panamá by Boutique Apartments

w Engaging 2BR in Casco Viejo

w Engaging 2BR in Casco Viejo
2.0 star property
Casco Viejo
The price is CA $192
CA $264 total
includes taxes & fees
May 6 - May 7
w Engaging 2BR in Casco Viejo

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (93 reviews)
"yes there was laundryroom, iron and nice pool. the stay was very good"
United States
melvin
The price is CA $115
CA $167 total
includes taxes & fees
May 5 - May 6
Casco View Apartments

Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (188 reviews)
"Our stay at Las Clementines was beyond compare! We chose it due to its wonderful location in Casco Antigua, but it was so much more. The staff was incredibly helpful and kind. Marcos told us the history of the hotel and took time to show us the details that make this place so wonderful. Mahalo, the restaurant, on the main floor makes absolutely delicious food...try the ceviche for sure. Overall, this was a highlight of our 8 day trip."
United States
Shelley
The price is CA $177
CA $195 total
includes taxes & fees
May 5 - May 6
Las Clementinas

La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (196 reviews)
"This was a beautiful property with tons of space inside and out. It was in a location easy for walking around to shops and restaurants. We only stayed one night but it would be fabulous for a longer stay. "
Canada
Jolene
The price is CA $194
CA $215 total
includes taxes & fees
May 3 - May 4
La Isabela Suites

Mini Design By Wynwood House

Mini Design By Wynwood House
3.0 star property
Bella Vista
10.0 out of 10, Exceptional, (2 reviews)
"The pool is amazing. I love that is it long enough to do laps if one would like a workout."
United States
Monica
The price is CA $173
CA $228 total
includes taxes & fees
May 3 - May 4
Mini Design By Wynwood House

La Palma Experience

La Palma Experience
3.0 star property
Amador
8.4 out of 10, Very good, (8 reviews)
"All ways clean and ready to used ,no buddy "
United States
Alberto
The price is CA $89
CA $98 total
includes taxes & fees
May 3 - May 4
La Palma Experience

Yoo Apartamento

Yoo Apartamento
3.0 star property
Bella Vista
9.4 out of 10, Exceptional, (18 reviews)
"Great location"
United States
Jimmy Lee
The price is CA $131
CA $205 total
includes taxes & fees
May 17 - May 18
Yoo Apartamento

La Cuadra by Wynwood House

La Cuadra by Wynwood House
3.0 star property
El Chorrillo
9.0 out of 10, Wonderful, (52 reviews)
"Second stay here and just as perfect as our first stay. "
United States
G. Jeffrey
The price is CA $129
CA $176 total
includes taxes & fees
May 4 - May 5
La Cuadra by Wynwood House

Studio Apartment with Ocean View

Studio Apartment with Ocean View
3.0 star property
Calidonia
8.0 out of 10, Very good, (3 reviews)
"It was similar to a hotel room, but a little smaller.. the bed is big enough for just one person and check in was the most difficult thing he had to wait outside in the rain and download apps"
United States
Gwendolyn
The price is CA $130
CA $143 total
includes taxes & fees
May 13 - May 14
Studio Apartment with Ocean View

Casa Love by Wynwood House

Casa Love by Wynwood House
3.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (24 reviews)
"Super "
France
Stephen
The price is CA $105
CA $154 total
includes taxes & fees
May 7 - May 8
Casa Love by Wynwood House

w Central 1BR in Vibrant Obarrio

w Central 1BR in Vibrant Obarrio
2.0 star property
Bella Vista
The price is CA $159
CA $220 total
includes taxes & fees
May 10 - May 11
w Central 1BR in Vibrant Obarrio

Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (3 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is CA $226
CA $458 total
includes taxes & fees
May 7 - May 8
Wanders Panama by Boutique Apartments

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
The price is CA $62
CA $279 total
includes taxes & fees
May 14 - May 15
Living 73 Panamá by Boutique Apartments
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama City Hotel Reviews

Find out more about Panama City

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Panama City. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Panama City?

Yes, we give you a choice of vacation rentals in Panama City near Panama Canal Railway, or you can choose a more remote option if you're looking for a relaxing stay. Tourists like the array of shops and lively bars in Panama City. While you're in the area, grab a bite or have a drink at the top-notch restaurants and cafes.

What's the top vacation rental in Panama City?

Oasis with pool near panama canal: This Panama City vacation home rental offers an outdoor pool, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind. Some other top choices in Panama City are Panama View House – A Hilltop Retreat with Stunning Canal Views and Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces.

How many vacation rentals are there in Panama City?

With 55 Expedia vacation rentals, you're sure to find just the right place for your Panama City stay.

What can I see and do in Panama City?

Cultural attractions include National Theater and Interoceanic Canal Museum, whereas Cinta Costera and Miraflores Locks are a couple of picturesque spots to enjoy the outdoors. Albrook Shopping Mall and Via Espana are other places to visit while you're in town.

What are vacation rentals like in Panama City?

Vacation rentals are privately owned accommodations you can stay in for several days or longer in Panama City. Vacation rentals offer amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about cleanliness, vacation rentals can provide a sense of safety away from public hotel elevators and busy lobbies while still allowing you to travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for families.