Title: Book the Best Panama City Adults Only Resorts & Hotels in 2026  | Expedia.ca

[Panama City Travel Guide](https://expedia.ca/Panama-City.dx2897)[Hotels in Panama City](https://expedia.ca/Panama-City-Hotels.d2897.Travel-Guide-Hotels)[Vacation Rentals in Panama City](https://expedia.ca/Panama-City-Vacation-Rentals.d2897.Travel-Guide-VacationRentals)[Flights to Panama City](https://expedia.ca/Cheap-Flights-To-Panama-City.d2897.Travel-Guide-Flights)[Things to do in Panama City](https://expedia.ca/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities)[Panama City Car Rentals](https://expedia.ca/Car-Rentals-In-Panama-City.d2897.Car-Rental-Guide)[Panama City Vacation Packages](https://expedia.ca/Panama-City.d2897.Destination-Travel-Guides)

![Panoramic view at the Downtown of Panama City - Panama](https://images.trvl-media.com/place/2897/e48f6143-9130-47fe-8b71-977ffb07b927.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find Adults Only Resorts & Hotels in Panama City 

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## Check availability on Panama City Adults Only Resorts & Hotels

Tonight

[Dec 14 - Dec 15](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2025-12-14&endDate=2025-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only)

Tomorrow

[Dec 15 - Dec 16](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2025-12-15&endDate=2025-12-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only)

Next weekend

[Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only)

In two weeks

[Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only)

## Our top choices for Panama City adults-only hotels

![Breakfast, lunch, dinner served; Fusion cuisine ](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/255ee499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Double by Cris Allende](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/3c62c55c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/c1c9d6fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Double by Cris Allende](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/db6dac9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tantalo Hotel

[](https://www.expedia.ca/Panama-City-Hotels-Tantalo-Hotel-Kitchen-Roofbar.h4880470.Hotel-Information)

Casco Viejo

8.8/10

Excellent

(274)

"My favorite place in Casco Viejo. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michael

[](https://www.expedia.ca/Panama-City-Hotels-Tantalo-Hotel-Kitchen-Roofbar.h4880470.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-28&endDate=2025-12-29&regionId=2897&adults=2&travelerType=adults_only&sort=RECOMMENDED&openPlayBack=true)

## Find out more about Panama City

### Discover top Panama City attractions

In Panama City, adventure meets culture at every turn, making it a thrilling destination for discerning travellers. Start your journey at the iconic Panama Canal, where you can witness the impressive locks in action and learn about its pivotal role in global trade at the Miraflores Visitor Centre. For a taste of local history, explore the Casco Viejo district, a UNESCO World Heritage site, where historic architecture and vibrant street art blend seamlessly, inviting you to wander its charming streets. Families will love visiting the Biomuseo, a museum dedicated to Panama's biodiversity, which features interactive exhibits that engage both children and adults alike. Nature enthusiasts can escape to Parque Natural Metropolitano, a sprawling urban park that boasts lush trails and stunning views of the city skyline, perfect for a family hike. Finally, don’t miss the SkyPark at the top of the Hard Rock Hotel, which offers a breathtaking infinity pool experience against the backdrop of the city below. For those seeking accommodation, the upscale neighbourhood of Avenida Balboa is an excellent choice, providing easy access to many of these attractions. Here, you’ll find luxurious hotels with world-class amenities and attentive service, ensuring a pampered stay. Imagine unwinding by the pool after a day of exploration, or enjoying a gourmet meal with panoramic views of the Pacific Ocean. With its blend of adventure, culture, and relaxation, Panama City promises to create lasting memories for you and your family.

### Find the best adults only resorts & hotels in Panama City 

For those seeking a romantic escape or a tranquil getaway without the presence of children, these hotels in Panama City are perfect for adults only, offering a serene atmosphere and luxurious amenities.  
  
[**Tantalo Hotel**](https://www.expedia.ca/Panama-City-Hotels-Tantalo-Hotel-Kitchen-Roofbar.h4880470.Hotel-Information)  

- **Why it's great for an adults only getaway:** A splendid choice for adult travellers, Tantalo Hotel in the vibrant Casco Viejo area offers an immersive experience with a strong traveler review rating of 8.8\. The hotel is exclusively for adults, ensuring a peaceful environment where travelers can unwind in style. The hotel features a stunning rooftop terrace, perfect for enjoying panoramic views of the city while sipping on expertly crafted cocktails.
- **Other amenities:** Guests will appreciate the convenient 24-hour airport shuttle service, valet parking, and daily housekeeping for a straightforward stay. The hotel's art deco design adds a touch of elegance, while the onsite shopping and concierge services cater to every need. Each room is equipped with premium bedding, air conditioning, and complimentary toiletries, ensuring maximum comfort throughout your visit.
- **Neighborhood:** Casco Viejo
- **Nearby attractions:** Avenida Balboa - 0.7 km, Metropolitan Cathedral of Panama - 0.4 km, National Theater - 1 km

## Top Panama City Hotel Reviews

## Frequently asked questions

### How much do adults-only hotels in Panama City cost?

### What are the best adults-only hotels in Panama City?

### Are there any adult-only all-inclusive resorts in Panama City?

### Are there any adult-only hotels with a balcony in Panama City?

### What is there to do in Panama City near my adults-only hotel?

### How can I find cheap adults-only hotels in Panama City?

### From what age can you stay in an adult-only hotel in Panama City?

### Are all adult-only resorts all-inclusive in Panama City?

### Why book your adults-only hotel in Panama City with Expedia?

### When is the best time to stay at an adult-only all-inclusive resort in Panama City?

### Can I cancel or change my adult-only resort booking?

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