Title: Book the Best Panama City Adults Only Resorts & Hotels in 2025 | Expedia.ca [Panama City Travel Guide](https://expedia.ca/Panama-City.dx2897)[Hotels in Panama City](https://expedia.ca/Panama-City-Hotels.d2897.Travel-Guide-Hotels)[Vacation Rentals in Panama City](https://expedia.ca/Panama-City-Vacation-Rentals.d2897.Travel-Guide-VacationRentals)[Flights to Panama City](https://expedia.ca/Cheap-Flights-To-Panama-City.d2897.Travel-Guide-Flights)[Things to do in Panama City](https://expedia.ca/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities)[Panama City Car Rentals](https://expedia.ca/Car-Rentals-In-Panama-City.d2897.Car-Rental-Guide)[Panama City Vacation Packages](https://expedia.ca/Panama-City.d2897.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Adults Only Resorts & Hotels in Panama City ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Panama City Adults Only Resorts & Hotels Tonight [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2025-10-30&endDate=2025-10-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Tomorrow [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2025-10-31&endDate=2025-11-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) ## Top Panama City Adults Only Resorts & Hotels ![Breakfast, lunch, dinner served; Fusion cuisine ](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/255ee499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/fab1c02b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/c1c9d6fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Double by Cris Allende](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/db6dac9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tantalo Hotel Casco Viejo 8.8/10 Excellent (273) "My favorite place in Casco Viejo. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael [](https://www.expedia.ca/Panama-City-Hotels-Tantalo-Hotel-Kitchen-Roofbar.h4880470.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-13&endDate=2025-11-14®ionId=2897&adults=2&travelerType=adults_only&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Panama City ### Discover top Panama City attractions In Panama City, adventure meets culture at every turn, making it a thrilling destination for discerning travellers. Start your journey at the iconic Panama Canal, where you can witness the impressive locks in action and learn about its pivotal role in global trade at the Miraflores Visitor Centre. For a taste of local history, explore the Casco Viejo district, a UNESCO World Heritage site, where historic architecture and vibrant street art blend seamlessly, inviting you to wander its charming streets. Families will love visiting the Biomuseo, a museum dedicated to Panama's biodiversity, which features interactive exhibits that engage both children and adults alike. Nature enthusiasts can escape to Parque Natural Metropolitano, a sprawling urban park that boasts lush trails and stunning views of the city skyline, perfect for a family hike. Finally, don’t miss the SkyPark at the top of the Hard Rock Hotel, which offers a breathtaking infinity pool experience against the backdrop of the city below. For those seeking accommodation, the upscale neighbourhood of Avenida Balboa is an excellent choice, providing easy access to many of these attractions. Here, you’ll find luxurious hotels with world-class amenities and attentive service, ensuring a pampered stay. Imagine unwinding by the pool after a day of exploration, or enjoying a gourmet meal with panoramic views of the Pacific Ocean. With its blend of adventure, culture, and relaxation, Panama City promises to create lasting memories for you and your family. ### Find the best adults only resorts & hotels in Panama City For those seeking a romantic escape or a tranquil getaway without the presence of children, these hotels in Panama City are perfect for adults only, offering a serene atmosphere and luxurious amenities. [Tantalo Hotel](https://www.expedia.ca/Panama-City-Hotels-Tantalo-Hotel-Kitchen-Roofbar.h4880470.Hotel-Information) - **Why it's great for an adults only getaway:** A splendid choice for adult travellers, Tantalo Hotel in the vibrant Casco Viejo area offers an immersive experience with a strong traveler review rating of 8.8. The hotel is exclusively for adults, ensuring a peaceful environment where travelers can unwind in style. The hotel features a stunning rooftop terrace, perfect for enjoying panoramic views of the city while sipping on expertly crafted cocktails. - **Other amenities:** Guests will appreciate the convenient 24-hour airport shuttle service, valet parking, and daily housekeeping for a straightforward stay. The hotel's art deco design adds a touch of elegance, while the onsite shopping and concierge services cater to every need. Each room is equipped with premium bedding, air conditioning, and complimentary toiletries, ensuring maximum comfort throughout your visit. - **Neighborhood:** Casco Viejo - **Nearby attractions:** Avenida Balboa - 0.7 km, Metropolitan Cathedral of Panama - 0.4 km, National Theater - 1 km ## Top Panama City Hotel Reviews ## Frequently asked questions ### How much do adults-only hotels in Panama City cost? > Costs for adults-only hotels in Panama City may vary depending on, among other things, the star rating and amenities provided by the hotel. Whatever your budget, you'll discover a grown-up getaway where you'll be able to unwind in peace and quiet with Expedia. ### What are the best adults-only hotels in Panama City? > A traveler favorite is [Tantalo Hotel](https://www.expedia.ca/Panama-City-Hotels-Tantalo-Hotel-Kitchen-Roofbar.h4880470.Hotel-Information). Cozy up at this 3.5-star adults-only hotel that offers a cafe and individually decorated rooms. [Luna's Castle Hostel](https://www.expedia.ca/Panama-City-Hotels-Lunas-Castle-Hostel.h31960311.Hotel-Information) is another impressive pick that caters exclusively to grown-ups. Unpack your bags at this 2-star property and take advantage of handy amenities including a rooftop terrace and a terrace. You can pick from 6 adults-only hotels in Panama City with a total average guest review rating of 8.6. ### Are there any adult-only all-inclusive resorts in Panama City? > Whether you're pampering your partner or kicking up your heels with pals, lock in your dream adult-only all-inclusive hotel or resort on Expedia. Spend your Panama City trip without the kiddos in tow at [Tantalo Hotel](https://www.expedia.ca/Panama-City-Hotels-Tantalo-Hotel-Kitchen-Roofbar.h4880470.Hotel-Information). This 3.5-star retreat comes with a cafe and individually decorated rooms, and is around 3 kilometres from the city center. For more all-inclusive, adults-only fun, check out [Niceplace Inn](https://www.expedia.ca/Panama-City-Hotels-Niceplace-Inn.h17772585.Hotel-Information). Around 3 kilometres from downtown, this 3-star rated pick features premium bedding, a rooftop terrace and more. ### Are there any adult-only hotels with a balcony in Panama City? > Take in a spectacular sunrise or sunset from your balcony at one of our adults-only hotels in Panama City. [Tantalo Hotel](https://www.expedia.ca/Panama-City-Hotels-Tantalo-Hotel-Kitchen-Roofbar.h4880470.Hotel-Information) is a superb choice if you're on vacation in Ancon. Conveniences here include individually decorated rooms and premium bedding. Another adult-only option in this city is [Niceplace Inn](https://www.expedia.ca/Panama-City-Hotels-Niceplace-Inn.h17772585.Hotel-Information). It comes with a rooftop terrace and premium bedding. Enjoy a morning brew on your balcony when you stay at this popular hotel. ### What is there to do in Panama City near my adults-only hotel? > Whatever you love to do, Panama City has plenty to capture your imagination. Metropolitan Cathedral of Panama, National Theater and Frank Gehry Biodiversity Museum are on many travelers' agendas. Don't go home without exploring Museum of History Panama, Afro Antillean Museum and Anita Villalaz Theater either. With Expedia's hotel deals in Panama City, you'll be able to discover even more renowned attractions like these with the money you save. ### How can I find cheap adults-only hotels in Panama City? > With Expedia's helpful filter tool, sourcing cheap adults-only hotels in Panama City is a breeze. Simply tailor your search results by star rating, budget and amenities to view accommodations that'll make your wallet smile. ### From what age can you stay in an adult-only hotel in Panama City? > Age restrictions to stay in an adult-only hotel may vary. To ensure you or any other guest satisfy the criteria, check the rules of the particular place in Panama City you're interested in. Generally, you have to be 16, 18 or 21. Just tied the knot and jetting off on your honeymoon? Or just want to have a blast with besties? Expedia's adult-only hotels and resorts are all about amazing experiences for all types of grown-up travelers. ### Are all adult-only resorts all-inclusive in Panama City? > If you long for a stress-free vacation, an adult-only all-inclusive resort serves up some serious R&R. To see what's available in Panama City, enter your dates of travel and then select the "all-inclusive" filter. Look out for stays listed as "adults only." Click on the properties you want to view to find out what you can expect for the price. The rate usually includes the room, drinks and food, on-site activities and daily entertainment. ### Why book your adults-only hotel in Panama City with Expedia? > Expedia has an excellent selection of adults-only hotels at competitive rates in Panama City. Take advantage of our search filters to click on how much you'd like to spend and then sort the results by price. Whether you're planning a couples break or want to party with pals, we'll help you find a perfect space. ### When is the best time to stay at an adult-only all-inclusive resort in Panama City? > Just about any time is a great time to stay at an adult-only all-inclusive resort in Panama City, but there are a few factors worth considering. Start with the time of year you'd like to travel. Peak season is lively and popular, but there may be a higher demand for both accommodations and flights. Low season is not as hectic and more reasonably priced. Of course, the weather plays an important part in making or breaking your getaway, so do some research before reserving your adult-only hotel or resort. ### Can I cancel or change my adult-only resort booking? > Yes. And there may be no charge depending on the type of adult-only hotel or resort booking you have. Check the fine print in your travel itinerary or make your way to Expedia's [Trips portal](https://www.expedia.ca/trips) for more information. Haven't booked anything yet? You can search for Panama City adult-only properties that provide full refunds — just in case. Reserve your grown-up getaway with the guarantee that wherever you stay, you'll have nothing to worry about! ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - [5 Star Hotels in Casco Viejo](https://www.expedia.ca/5Star-Casco-Viejo-Panama-City-Hotels.s50-n6285189-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Punta Pacifica](https://www.expedia.ca/5Star-Punta-Pacifica-Panama-City-Hotels.s50-n3000663482-0.Travel-Guide-Filter-Hotels) - [Hotels near Albrook Shopping Mall](https://www.expedia.ca/Albrook-Shopping-Mall-Hotels.0-l6159851-0.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Amador](https://www.expedia.ca/Amador-Panama-City-Hotels-Beach-Hotel.0-n553248635933392377-0-tBeachHotel.Travel-Guide-Filter-Hotels) - [Lgbt Friendly Hotels in Amador](https://www.expedia.ca/Amador-Panama-City-Hotels-LGBT-Friendly-Hotel.0-n553248635933392377-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels near Avenida Balboa](https://www.expedia.ca/Avenida-Balboa-Hotels.0-l553248623453290531-0.Travel-Guide-Filter-Hotels) - 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Gelabert Intl.](https://www.expedia.ca/lp/airports/pac/flights-from-marcos-a-gelabert-intl-airport) - [Flights from Bocas del Toro (BOC) to Panama City (PAC)](https://www.expedia.ca/lp/flights/boc/pac/bocas-del-toro-to-panama-city) - [Flights from Changuinola (CHX) to Panama City (PAC)](https://www.expedia.ca/lp/flights/chx/pac/changuinola-to-panama-city) - [Flights from Merida (MID) to Panama City (PAC)](https://www.expedia.ca/lp/flights/mid/pac/merida-to-panama-city) - [Flights from Panama City (PTY) to Panama City (PAC)](https://www.expedia.ca/lp/flights/pty/pac/panama-city-to-panama-city) - [Flights from Puerto Vallarta (PVR) to Panama City (PAC)](https://www.expedia.ca/lp/flights/pvr/pac/puerto-vallarta-to-panama-city) - [Flights from Rio Hato (RIH) to Panama City (PAC)](https://www.expedia.ca/lp/flights/rih/pac/rio-hato-to-panama-city) - [Flights from Tambor (TMU) to Panama City (PAC)](https://www.expedia.ca/lp/flights/tmu/pac/tambor-to-panama-city) - [Flights from Edmonton (YEG) to Panama City (PAC)](https://www.expedia.ca/lp/flights/yeg/pac/edmonton-to-panama-city) - [Flights from Montreal (YUL) to Panama City (PAC)](https://www.expedia.ca/lp/flights/yul/pac/montreal-to-panama-city) - [Flights from Vancouver (YVR) to Panama City (PAC)](https://www.expedia.ca/lp/flights/yvr/pac/vancouver-to-panama-city) - [Flights from Calgary (YYC) to Panama City (PAC)](https://www.expedia.ca/lp/flights/yyc/pac/calgary-to-panama-city) - [Flights from Toronto (YYZ) to Panama City (PAC)](https://www.expedia.ca/lp/flights/yyz/pac/toronto-to-panama-city) - [Albrook Shopping Mall](https://www.expedia.ca/Albrook-Shopping-Mall-Panama-City.d6159851.Vacation-Attraction) - [Avenida Balboa](https://www.expedia.ca/Avenida-Balboa-Calidonia.d553248623453290531.Vacation-Attraction) - [Cinta Costera](https://www.expedia.ca/Cinta-Costera-Calidonia.d6245970.Vacation-Attraction) - [Club de Clases y Tropas](https://www.expedia.ca/Club-De-Clases-Y-Tropas-Casco-Viejo.d553248621532965263.Vacation-Attraction) - [El Dorado Mall](https://www.expedia.ca/El-Dorado-Mall-Bethania.d553248621532963614.Vacation-Attraction) - [Metropolitan Nature Park](https://www.expedia.ca/Metropolitan-Nature-Park-Panama-City.d6078485.Vacation-Attraction) - [Multiplaza Pacific Mall](https://www.expedia.ca/Multiplaza-Pacific-Mall-San-Francisco.d6158227.Vacation-Attraction) - [Omar Torrijos Recreational Park](https://www.expedia.ca/Omar-Torrijos-Recreational-Park-San-Francisco.d553248621532964848.Vacation-Attraction) - [Visit Bella Vista](https://www.expedia.ca/Panama-City-Bella-Vista.dx3000663485) - [Visit Calidonia](https://www.expedia.ca/Panama-City-Calidonia.dx3000663488) - [Visit Campo Alegre](https://www.expedia.ca/Panama-City-Campo-Alegre.dx553248635976397615) - [Visit Casco Viejo](https://www.expedia.ca/Panama-City-Casco-Viejo.dx6285189) - [Visit Curundu](https://www.expedia.ca/Panama-City-Curundu.dx553248623199107736) - [Visit El Cangrejo](https://www.expedia.ca/Panama-City-El-Cangrejo.dx6285972) - [Visit Marbella](https://www.expedia.ca/Panama-City-Marbella.dx3000663483) - [Visit Obarrio](https://www.expedia.ca/Panama-City-Obarrio.dx3000663487) - [Visit Punta Pacifica](https://www.expedia.ca/Panama-City-Punta-Pacifica.dx3000663482) - [Visit Punta Paitilla](https://www.expedia.ca/Panama-City-Punta-Paitilla.dx6285983) - [Visit San Francisco](https://www.expedia.ca/Panama-City-San-Francisco.dx553248623199112076) - [Panamá Province Vacations](https://www.expedia.ca/Panama-Province.d6246281.Destination-Travel-Guides) - [Visit Panamá Province](https://www.expedia.ca/Panama-Province.dx6246281) - [Uruguay Street](https://www.expedia.ca/Uruguay-Street-Bella-Vista.d6294103.Vacation-Attraction) - [Car rentals near Albrook Shopping Mall](https://www.expedia.ca/Car-Rentals-In-Albrook-Shopping-Mall.d6159851.Car-Rental-Guide) - [Car rentals near Panama Canal Murals](https://www.expedia.ca/Car-Rentals-In-Panama-Canal-Murals.d553248621532965255.Car-Rental-Guide) - [Car rentals near Uruguay Street](https://www.expedia.ca/Car-Rentals-In-Uruguay-Street.d6294103.Car-Rental-Guide) - [Panamá Province Vacation Rentals](https://www.expedia.ca/Destinations-In-Panama-Province.d6246281.Vacation-Rental-Destinations)