A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

4 Star Hotels in Panama City CA $133

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Check availability on Panama City 4 Star Hotels

Tonight
Sep 21 - Sep 22
Tomorrow
Sep 22 - Sep 23
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Panama City 4-star hotels

1. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
Tocumen Airport
United States
Xenia
CA $171
CA $197 total
includes taxes & fees
Oct 1 - Oct 2
Crowne Plaza Panama Airport by IHG

2. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
United States
Olga
CA $257
CA $282 total
includes taxes & fees
Oct 21 - Oct 22
Central Hotel Panama Casco Viejo

3. Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Bella Vista
United States
abbigale
CA $131
CA $144 total
includes taxes & fees
Oct 18 - Oct 19
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
Devika
CA $194
CA $194 total
includes taxes & fees
Oct 1 - Oct 2
Megapolis Hotel Panamá

5. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
United States
Abeke
CA $89
CA $176 total
includes taxes & fees
Sep 26 - Sep 27
Waymore Hotel Spa & Casino

6. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
United States
Joanna
CA $389
CA $389 total
includes taxes & fees
Oct 1 - Oct 2
Dreams Playa Bonita Panama - All Inclusive

7. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
San Antonio
United States
Stephen
CA $137
CA $150 total
includes taxes & fees
Oct 2 - Oct 3
Courtyard by Marriott Panama Metromall

8. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
Tocumen Airport
United States
Tanese
CA $151
CA $167 total
includes taxes & fees
Sep 29 - Sep 30
Riande Aeropuerto Hotel & Casino

9. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
San Francisco
United States
Maria
CA $137
CA $151 total
includes taxes & fees
Oct 3 - Oct 4
Ramada Plaza by Wyndham Panama Punta Pacifica

10. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
San Francisco
United States
Holly
CA $153
CA $169 total
includes taxes & fees
Oct 3 - Oct 4
Courtyard by Marriott Panama Multiplaza Mall

11. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
San Francisco
United States
Armando
CA $205
CA $226 total
includes taxes & fees
Sep 22 - Sep 23
Las Americas Golden Tower Panama

12. Marriott Panama Hotel

Marriott Panama Hotel
Panama City
United States
Richard
CA $236
CA $260 total
includes taxes & fees
Oct 10 - Oct 11
Marriott Panama Hotel

13. Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
United States
Jorge Luis
CA $140
CA $154 total
includes taxes & fees
Oct 10 - Oct 11
Decapolis Hotel Panama City

14. Sheraton Grand Panama

Sheraton Grand Panama
San Francisco
United States
Roxanne Bailey
CA $245
CA $270 total
includes taxes & fees
Oct 2 - Oct 3
Sheraton Grand Panama

15. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
Amador
United Kingdom
Samantha
CA $133
CA $146 total
includes taxes & fees
Oct 3 - Oct 4
Radisson Hotel Panama Canal

16. Studio Coliving

Studio Coliving
Bella Vista
United States
Phillip
Studio Coliving

17. Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Bella Vista
United States
Charles
CA $278
CA $306 total
includes taxes & fees
Sep 22 - Sep 23
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

18. Novotel Panama City

Novotel Panama City
Bella Vista
United States
Philip
CA $121
CA $133 total
includes taxes & fees
Oct 18 - Oct 19
Novotel Panama City

19. American Trade Hotel

American Trade Hotel
Casco Viejo
United States
James
CA $251
CA $276 total
includes taxes & fees
Oct 1 - Oct 2
American Trade Hotel

20. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
United States
Reid
CA $391
CA $430 total
includes taxes & fees
Oct 2 - Oct 3
Hotel La Compañía Casco Antiguo
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Panama City.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
CA $193
CA $212 total
Sep 28 - Sep 29
includes taxes & fees
Hotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

47th St. & Uruguay Street Panama City Panama
CA $366
CA $402 total
Oct 10 - Oct 11
includes taxes & fees
9/10 Wonderful! (1,000 reviews)
Waldorf Astoria Panama
JW Marriott Panama

JW Marriott Panama

Calle Punta Colon, Punta Pacifica Panama City Panama
CA $368
CA $405 total
Oct 10 - Oct 11
includes taxes & fees
9.2/10 Wonderful! (1,005 reviews)
JW Marriott Panama
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Top Panama City Hotel Reviews

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

8/10 Good
"I requested late check out when I checked in. We agreed on a set time. I was called twice during the extended time and housekeeping attempted to enter between those calls. Their communication is poor and the staff were hardly apologetic, except for the housekeeper. Evidently a notation for late check out wasn’t made or it wasn’t read by the staff."
Mervin 1-night trip
Posted 14 hours ago
Ramada Plaza by Wyndham Panama Punta Pacifica
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

8/10 Good
"First of all I was a little disappointed that hardly anyone on a property spoke English,😡 I didn't know that before I booked it. The breakfast buffet, was off the hook a lot of choices food was great. The hallway on the way to the elevator from the 4th floor was quite dirty. My room was great everything was good inside there, but their window to look out over the city was very dirty."
Lawrence 4-night trip
Posted 16 hours ago
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

8/10 Good
"The hotel was centrally locale to a number of restaurants, clean and kept tidy. The breakfast was decent with fresh fruit and offerings which varied daily. Easy access to to malls by uber. Would stay again and definitely recommend"
Campbell 4-night trip
Posted 18 hours ago
Waymore Hotel Spa & Casino
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

10/10 Excellent
"Such a great experience! I’d recommend it to anyone and love to stay again."
Joshua 2-night trip
Posted 23 hours ago
Central Hotel Panama Casco Viejo

Price trends for properties with 4 Stars in Panama City

Less expensive
More expensive
Next month
July
January
CA $193
Month
Price
January
CA $208
February
CA $188
March
CA $188
April
CA $185
May
CA $186
June
CA $208
July
CA $184
August
CA $191
September
CA $199
October
CA $193
November
CA $190
December
CA $202
Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed properties with 4 stars in Panama City. Select dates and complete search for nightly totals inclusive of taxes and fees.

Find out more about Panama City

If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Panama City are calling your name. Known for providing first-rate service in amazing locations, each of the Panama City 4 Stars hotels lets discerning travelers bask in an unforgettable experience.

Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day.

It’s all waiting for you at the top four star hotels in Panama City. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Panama City, Panamá Province, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Panama City hotels with 4 Stars provide everything you need to unwind in style.

Frequently asked questions

What are the best 4-star hotels in Panama City?
If you're seeking luxury comfort and loads of amenities on your Panama City getaway, consider Renaissance Panama City Hotel. This leading 4-star hotel features room service and pillow top mattresses. Panama Marriott Hotel also gets stellar reviews from Expedia travellers. A spa tub and proposal/romance packages are among its conveniences.
How much does it cost to stay in a 4-star hotel in Panama City?
With Expedia's sort and search filters, bagging a terrific deal on a 4-star hotel in Panama City just got easier. Start by keying in your chosen travel dates and length of your getaway. Then sort the results by price and choose the option that best suits your style and budget.
  • Search for the lowest price from CA $212
What's the difference between 5-star and 4-star hotels in Panama City?
If you choose to book a stay at a 4-star hotel in Panama City, you'll typically find loads of conveniences to ensure you're comfortable, such as a restaurant, gym and pool. You can enjoy high-quality service and upmarket surroundings. Go for a 5-star hotel and you'll get a few extra perks — think on-site spas, around-the-clock concierge and opulent turndown services. You're likely to get more amenities and exclusive services at a 5-star getaway, but both are awesome options for luxury guests.

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