A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

5 Stars Hotels in Panama City, Panamá Province from CA $198

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Check availability on Panama City 5 Star Hotels

Next weekend
Jul 3 - Jul 5
In two weeks
Jul 10 - Jul 12

Our top choices for Panama City 5-star hotels

Outdoor pool, sun loungers

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (5,645 reviews)
"Great Location, good food."
United States
Yohan
The price is CA $197
CA $217 total
includes taxes & fees
Jun 30 - Jul 1
Hotel Riu Plaza Panama
2 bars/lounges, poolside bar

Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,002 reviews)
"yes, nice breakfast"
United States
Fernando
The price is CA $404
CA $444 total
includes taxes & fees
Jul 3 - Jul 4
Waldorf Astoria Panama
Restaurant

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,003 reviews)
"Very clean nice staff and convenient"
United States
Ruth P
The price is CA $353
CA $389 total
includes taxes & fees
Jul 3 - Jul 4
W Panama
Room, 1 King Bed, Balcony, Oceanfront (Magnifique)

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (672 reviews)
"Beautiful hotel, excellent options for food and drinks within the hotel and nearby, and the staff was very attentive and helpful"
United States
Gabriel
The price is CA $428
CA $471 total
includes taxes & fees
Jul 27 - Jul 28
Sofitel Legend Casco Viejo, Panama City
4 outdoor pools, free cabanas, pool umbrellas

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,001 reviews)
"Great hotel. Highly recommend"
United States
Robert
The price is CA $385
CA $423 total
includes taxes & fees
Jul 11 - Jul 12
JW Marriott Panama
Outdoor pool, pool umbrellas

Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Bella Vista
9.6 out of 10, Exceptional, (351 reviews)
"Great stay! We enjoyed the hospitality!"
United States
Craig
The price is CA $309
CA $340 total
includes taxes & fees
Jul 18 - Jul 19
Hyatt Regency Panama City
40-inch Smart TV with cable channels, TV

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (235 reviews)
"Breakfast was very good, staff are very helpful and friendly "
United States
Farah
The price is CA $180
CA $198 total
includes taxes & fees
Jul 5 - Jul 6
Renaissance Panama City Hotel
View from property

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (706 reviews)
"Stunning ! Beautiful Hotel ! Excelent Service Delicious Food Luxury modern room Can’t wait to go back ! Love it so much !"
United States
Marina
The price is CA $382
CA $420 total
includes taxes & fees
Jul 4 - Jul 5
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
3 outdoor pools, pool umbrellas, sun loungers

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very good, (1,000 reviews)
"This is an excellent hotel and would highly recommend."
United States
Shernon
The price is CA $293
CA $322 total
includes taxes & fees
Jul 10 - Jul 11
The Westin Playa Bonita Panama
Outdoor pool

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,000 reviews)
"Very nice hotel in the heart of the city. Friendly staff and very nice rooms."
United States
Ashley
The price is CA $351
CA $386 total
includes taxes & fees
Jul 26 - Jul 27
Hilton Panama
Couples treatment rooms, sauna, steam room, body treatments

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.4 out of 10, Exceptional, (1,000 reviews)
"Great Hotel and location, the staff was very friendly, we enjoyed our stay."
United States
Rafael
The price is CA $316
CA $347 total
includes taxes & fees
Jul 18 - Jul 19
Bristol Panama, a Registry Collection Hotel
View from property

Megapolis Hotel Panamá

Megapolis Hotel Panamá
5.0 star property
San Francisco
8.4 out of 10, Very good, (1,000 reviews)
"Great stay! Very safe!"
United States
MARVIN
Megapolis Hotel Panamá
Lobby

Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
5.0 star property
Bella Vista
6.2 out of 10, (1,000 reviews)
"It has a nice casino and it's very conveniently located. Breakfast was very good as well. Staff very helpful and attention oriented. Good experience "
United States
Aldo
Waymore Hotel Spa and Casino
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
The price is CA $180 per night from Jul 20 to Jul 21
CA $180
CA $208 total
Jul 20 - Jul 21
includes taxes & fees
8.6/10 Excellent! (2,602 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Top Panama City Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

8/10 Good
"Breakfast qqas amazing"
Shellisa 7-night trip
Posted 10 hours ago
Hotel Riu Plaza Panama

Find out more about Panama City

Five Star Hotels in Panama City

There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Panama City so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Panama City and get ready to be pampered like never before.

Get a Great Deal on 5-Star Hotels in Panama City

Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places.

Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town.

Make Your Escape to Panama City

The results are in, and Panama City 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Panama City! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Panama City today and settle down in the lap of luxury tomorrow.

Frequently asked questions

What are the best 5-star hotels in Panama City?
Based on Expedia guest reviews, Bristol Panama, a Registry Collection Hotel, W Panama and Hotel Riu Plaza Panama are among the most popular 5-star hotels in Panama City. Featuring top-quality amenities and excellent service, you'll enjoy a luxurious and memorable stay.
How much does it cost to stay in a 5-star hotel in Panama City?
How much you pay for a 5-star hotel in Panama City depends on factors like when you plan to travel and the length of your break. A top tip for bagging the best deal? Use our pricing filters to check out all of the available options for your preferred dates.

  • Search for the lowest price per night from CA $203

What makes a hotel 5 stars in Panama City?
From gourmet dining venues and 24-hour gyms to swimming pools and premium bedding, the 5-star experience in Panama City is all about comfort and luxury. But it requires more than just top-notch conveniences to receive a 5-star rating. Stays must also deliver exceptional guest-focused services like in-room massages, on-site dry cleaning and laundry and a nightly turn-down service.

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