Title: 5 Stars Hotels in Panama City, Panamá Province from CA $182 - Find Cheap Panama City Hotels With 5 Stars | Expedia.ca [Panama City Travel Guide](https://expedia.ca/Panama-City.dx2897)[Hotels in Panama City](https://expedia.ca/Panama-City-Hotels.d2897.Travel-Guide-Hotels)[Vacation Rentals in Panama City](https://expedia.ca/Panama-City-Vacation-Rentals.d2897.Travel-Guide-VacationRentals)[Flights to Panama City](https://expedia.ca/Cheap-Flights-To-Panama-City.d2897.Travel-Guide-Flights)[Things to do in Panama City](https://expedia.ca/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities)[Panama City Car Rentals](https://expedia.ca/Car-Rentals-In-Panama-City.d2897.Car-Rental-Guide)[Panama City Vacation Packages](https://expedia.ca/Panama-City.d2897.Destination-Travel-Guides) ![Panoramic view at the Downtown of Panama City - Panama](https://images.trvl-media.com/place/2897/e48f6143-9130-47fe-8b71-977ffb07b927.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/2897/e48f6143-9130-47fe-8b71-977ffb07b927.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Panama City 5 Star Hotels Tonight [Feb 7 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2026-02-07&endDate=2026-02-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 8 - Feb 9](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2026-02-08&endDate=2026-02-09&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2026-02-13&endDate=2026-02-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2026-02-20&endDate=2026-02-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Panama City 5-star hotels ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/f2fa3d9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (In the heart of the City) | City view](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/81e63597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/096c0ccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza Panama [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) Bella Vista 9.0/10 Wonderful (4,925 reviews) " Nice hotel and great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wajdi CA $180 CA $198 total includes taxes & fees Mar 10 - Mar 11 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/bd4cfae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/cf22e531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/4a63a156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waldorf Astoria Panama [](https://www.expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) Bella Vista 9.0/10 Wonderful (1,002 reviews) "Staff was super nice and room was great we also ate on the rooftop and food was great!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Tim CA $302 CA $332 total includes taxes & fees Mar 7 - Mar 8 [](https://www.expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![2 restaurants, local cuisine](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/1175365b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Urban Suite,1 King, Partial City view](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/0b373179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse I, Suite, 1 King, Partial City view | Living room](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/c594bc6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W Panama [](https://www.expedia.ca/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) Bella Vista 9.0/10 Wonderful (1,001 reviews) "Second time staying and it was flawless." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anthony CA $251 CA $276 total includes taxes & fees Mar 7 - Mar 8 [](https://www.expedia.ca/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![4 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/w3996h2667x4y0-a167c2ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/0babe4e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/08d313d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Panama [](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) San Francisco 9.0/10 Wonderful (1,006 reviews) "Beautiful hotel, great service. Breakfast buffet is amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tamara CA $382 CA $420 total includes taxes & fees Mar 7 - Mar 8 [](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Room, 1 King Bed, Balcony, Oceanfront (Magnifique)](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/ccd122a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury 1 King, Ocean Front](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/baaa5cb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/9fe67709.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/88416317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel Legend Casco Viejo, Panama City [](https://www.expedia.ca/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information) Casco Viejo 9.8/10 Exceptional (587 reviews) "Beautiful place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose CA $511 CA $563 total includes taxes & fees Feb 23 - Feb 24 [](https://www.expedia.ca/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information) ![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/99beffbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/37502420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch served; American cuisine](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/17d1dc17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch served; American cuisine](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/eb1560c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Panama [](https://www.expedia.ca/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) Bella Vista 8.8/10 Excellent (1,004 reviews) "Huge hotel wit" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katya CA $288 CA $317 total includes taxes & fees Mar 7 - Mar 8 [](https://www.expedia.ca/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) ![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/e50f6f0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/0311490e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/0e5b4d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/ed6fb5fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Playa Bonita Panama [](https://www.expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) Veracruz 8.0/10 Very good (1,012 reviews) "Beautiful property and amazing staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) CARMEN CA $324 CA $356 total includes taxes & fees Mar 9 - Mar 10 [](https://www.expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/4235e7f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/a2139207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; pool views](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/5ca43e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/d4b0e49b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renaissance Panama City Hotel [](https://www.expedia.ca/Panama-City-Hotels-Renaissance-Panama-City-Hotel.h527169.Hotel-Information) Bella Vista 8.8/10 Excellent (144 reviews) "Very good hotel, well located. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrés CA $174 CA $191 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Panama-City-Hotels-Renaissance-Panama-City-Hotel.h527169.Hotel-Information) ![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/620cc150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/86dd447e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Yoga](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/79b76059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bristol Panama, a Registry Collection Hotel [](https://www.expedia.ca/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) Bella Vista 9.4/10 Exceptional (1,004 reviews) "All was perfect for our Christmas vacation - staff food and rooms - would definitely stay here again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) PROBIR MAYUR CA $286 CA $315 total includes taxes & fees Feb 27 - Feb 28 [](https://www.expedia.ca/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/3972c3df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/166e4001.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/c579d87e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/ea9ff933.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City [](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) Juan Diaz 9.6/10 Exceptional (660 reviews) "As usual the stay was amazing in this hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose CA $368 CA $405 total includes taxes & fees Mar 7 - Mar 8 [](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/449ce738.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/ca08becf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/0b1e4b11_edited_cdf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/90613175.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Megapolis Hotel Panamá [](https://www.expedia.ca/Panama-City-Hotels-Megapolis-Hotel-Panama.h5074269.Hotel-Information) San Francisco 8.4/10 Very good (1,001 reviews) "Great stay! Very safe!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARVIN [](https://www.expedia.ca/Panama-City-Hotels-Megapolis-Hotel-Panama.h5074269.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/e6ea2c2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/c1888432.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/9750e503.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/b050eac6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waymore Hotel Spa and Casino [](https://www.expedia.ca/Panama-City-Hotels-Veneto-Hotel-Casino.h1410053.Hotel-Information) Bella Vista 6.2/10 (1,000 reviews) "It has a nice casino and it's very conveniently located. Breakfast was very good as well. Staff very helpful and attention oriented. Good experience " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aldo [](https://www.expedia.ca/Panama-City-Hotels-Veneto-Hotel-Casino.h1410053.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Panama-City-Hotels.s50-0-d2897.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Panama-City-Hotels.s50-0-d2897.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City. ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Crowne Plaza Panama Airport by IHG Ave. Domingo Diaz Tocumen Panama CA $165 CA $182 total Feb 12 - Feb 13 includes taxes & fees 8.4/10 Very Good! (2,421 reviews) [](https://expedia.ca/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Megapolis Hotel Panamá Avenida Balboa Panama City CA $316 CA $347 total Feb 8 - Feb 9 includes taxes & fees 8.4/10 Very Good! (1,408 reviews) [](https://expedia.ca/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Las Americas Golden Tower Panama Av. Balboa con Calle 53 Panama City Panama CA $235 CA $261 total Mar 1 - Mar 2 includes taxes & fees 8.8/10 Excellent! (1,010 reviews) [](https://expedia.ca/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) Still don't see what you're looking for? [See all properties in Panama City.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F02%2F2026&endDate=09%2F02%2F2026®ionId=2897&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F02%2F2026&endDate=09%2F02%2F2026®ionId=2897&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F02%2F2026&endDate=09%2F02%2F2026®ionId=2897&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F02%2F2026&endDate=09%2F02%2F2026®ionId=2897&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F02%2F2026&endDate=09%2F02%2F2026®ionId=2897&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F02%2F2026&endDate=09%2F02%2F2026®ionId=2897&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Panama City The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch. [See all hotels in Panama City](https://www.expedia.ca/Hotel-Search?startDate=2026-02-21&endDate=2026-02-22&adults=2®ionId=2897) ![Panoramic view at the Downtown of Panama City - Panama](https://images.trvl-media.com/place/2897/e48f6143-9130-47fe-8b71-977ffb07b927.jpg?impolicy=fcrop&w=900&h=336&p=1&q=high) ## Top Panama City Hotel Reviews ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "The Riu hotel in Panama City is wonderful ! The buffet breakfast is plentiful. The rooms are spacious and the location is very convenient. They have a beautiful pool and a lovely restaurant adjacent to it. I certainly don’t have any complaints !" [](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "Room size" [](https://expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg) ### W Panama 10/10 Excellent "Clean room staff everything was amazing " [](https://expedia.ca/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "Beautiful hotel, great service. Breakfast buffet is amazing. " [](https://expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ## Find out more about Panama City ## Five Star Hotels in Panama City There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Panama City so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Panama City and get ready to be pampered like never before. #### Get a Great Deal on 5-Star Hotels in Panama City Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places. Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town. #### Make Your Escape to Panama City The results are in, and Panama City 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Panama City! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Panama City today and settle down in the lap of luxury tomorrow. ## Frequently asked questions ### What are the best 5-star hotels in Panama City? ### How much does it cost to stay in a 5-star hotel in Panama City? > - Search for the lowest price per night from CA $182 ### What makes a hotel 5 stars in Panama City? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - [5 Star Hotels in Casco Viejo ](https://www.expedia.ca/5Star-Casco-Viejo-Panama-City-Hotels.s50-n6285189-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Punta Pacifica ](https://www.expedia.ca/5Star-Punta-Pacifica-Panama-City-Hotels.s50-n3000663482-0.Travel-Guide-Filter-Hotels) - [Hotels near Albrook Shopping Mall ](https://www.expedia.ca/Albrook-Shopping-Mall-Hotels.0-l6159851-0.Travel-Guide-Filter-Hotels) - [Hotels near Avenida Balboa ](https://www.expedia.ca/Avenida-Balboa-Hotels.0-l553248623453290531-0.Travel-Guide-Filter-Hotels) - [Barrio Chino Hotels ](https://www.expedia.ca/Barrio-Chino-Panama-City-Hotels.0-n714749931894550528-0.Travel-Guide-Filter-Hotels) - 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