Title: 5 Stars Hotels in Panama City, Panamá Province from CA $151 - Find Cheap Panama City Hotels With 5 Stars | Expedia.ca [Panama City Travel Guide](https://expedia.ca/Panama-City.dx2897)[Hotels in Panama City](https://expedia.ca/Panama-City-Hotels.d2897.Travel-Guide-Hotels)[Vacation Rentals in Panama City](https://expedia.ca/Panama-City-Vacation-Rentals.d2897.Travel-Guide-VacationRentals)[Flights to Panama City](https://expedia.ca/Cheap-Flights-To-Panama-City.d2897.Travel-Guide-Flights)[Things to do in Panama City](https://expedia.ca/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities)[Panama City Car Rentals](https://expedia.ca/Car-Rentals-In-Panama-City.d2897.Car-Rental-Guide)[Panama City Vacation Packages](https://expedia.ca/Panama-City.d2897.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in Panama City, Panamá Province from CA $151 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Panama City 5 Star Hotels Tonight [Oct 18 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2025-10-18&endDate=2025-10-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 19 - Oct 20](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2025-10-19&endDate=2025-10-20&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=2897&startDate=2025-10-31&endDate=2025-11-02&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Panama City 5 Star Hotels ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/ec5ee8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/096c0ccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (In the heart of the City)](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/c6c3b77c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza Panama Bella Vista 9.0/10 Wonderful (4422) "Great hotel! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Keesha CA $166 CA $183 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hot tub, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/361a474e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/a7b599bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/cf22e531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waldorf Astoria Panama Bella Vista 9.0/10 Wonderful (1002) "Absolutely fantastic experience. Beautiful property, wonderful staff, great food. Exceptional " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $263 CA $290 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![4 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/22b0bcbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/0babe4e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/3994d56c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Panama San Francisco 8.8/10 Excellent (1018) "The staff is top notch, the accommodations amazing, the dining options great, close to airport and activities " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Natilsha Rewnawlda CA $309 CA $340 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![2 restaurants, local cuisine](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse I, Suite, 1 King, Partial City view | Living room](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/c594bc6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Supreme Suite, 1 King, Partial City view, Corner room](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/d1c75b6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/557ce8bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W Panama Bella Vista 9.0/10 Wonderful (1009) "Nice clean property in a good area" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rodney CA $257 CA $283 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/fae422a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/3e3dec8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/ba99cac1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/edb97b6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel Legend Casco Viejo, Panama City Casco Viejo 9.8/10 Exceptional (519) "Great hotel and location " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Russell CA $410 CA $451 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information) ![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Classic, 1 King Bed, Non-Smoking](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8ec9f171.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8e0cdd04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/c4347824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bristol Panama, a Registry Collection Hotel Bella Vista 9.2/10 Wonderful (1009) "We had an amazing time, great hotel and great breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Priscila CA $264 CA $290 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) ![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, 2 poolside bars, swim-up bar](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/a12fa485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, sun loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/e679a1c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/0e5b4d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Playa Bonita Panama Veracruz 8.0/10 Very good (1006) "Only here for a short stay, but enjoyed the facilities and staff!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Leona CA $233 CA $257 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![40-inch Smart TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/d8dfdd09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/9cd155ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/136ac6a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/0dc8ead7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renaissance Panama City Hotel Bella Vista 9.0/10 Wonderful (72) "The Room was very clean, all staff were very kind and professional, the breakfast and dinner are so delicious, nothing comparative with other restaurant around. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ariel Susset CA $137 CA $151 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Panama-City-Hotels-Renaissance-Panama-City-Hotel.h527169.Hotel-Information) ![Suite, 1 Bedroom, Non Smoking, Golf View (Terrace)](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/d80494b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/1e4d9048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/c77947e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/e5856e04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City Juan Diaz 9.6/10 Exceptional (618) "The staff were fantastic. The service was great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) SANDRO CA $304 CA $334 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/ae99e466.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/5b5af4d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/99beffbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/8590a017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Panama Bella Vista 8.8/10 Excellent (1003) "Great property You don’t go wrong Amenities are great Location is perfect area safe and walkable rooms are nice large clean modern " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Suzanne CA $315 CA $346 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/0b1e4b11_edited_cdf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/ebc5847c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/90613175.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bars/lounges, tapas bar](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074269/b225554a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Megapolis Hotel Panamá San Francisco 8.4/10 Very good (1001) "Great stay! Very safe!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARVIN [](https://www.expedia.ca/Panama-City-Hotels-Megapolis-Hotel-Panama.h5074269.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/9750e503.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/e6ea2c2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily breakfast for a fee](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/3e21e88d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410053/67ba0beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waymore Hotel Spa and Casino Bella Vista 6.2/10 (1001) "It has a nice casino and it's very conveniently located. Breakfast was very good as well. Staff very helpful and attention oriented. Good experience " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aldo [](https://www.expedia.ca/Panama-City-Hotels-Veneto-Hotel-Casino.h1410053.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Panama-City-Hotels.s50-0-d2897.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Panama-City-Hotels.s50-0-d2897.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City. ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Crowne Plaza Panama Airport by IHG Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama CA $163 CA $179 total Nov 1 - Nov 2 includes taxes & fees [](https://expedia.ca/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sheraton Grand Panama Via Israel And 77th Street, Panama City, Panama CA $188 CA $207 total Nov 1 - Nov 2 includes taxes & fees [](https://expedia.ca/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Marriott Panama Hotel Roosevelt Ave., Allbrook Mall, Panama City, Panama CA $188 CA $207 total Nov 7 - Nov 8 includes taxes & fees [](https://expedia.ca/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) Still don't see what you're looking for? [See all properties in Panama City.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F10%2F2025&endDate=21%2F10%2F2025®ionId=2897&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F10%2F2025&endDate=21%2F10%2F2025®ionId=2897&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F10%2F2025&endDate=21%2F10%2F2025®ionId=2897&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F10%2F2025&endDate=21%2F10%2F2025®ionId=2897&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F10%2F2025&endDate=21%2F10%2F2025®ionId=2897&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F10%2F2025&endDate=21%2F10%2F2025®ionId=2897&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Panama City The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch. [See all hotels in Panama City](https://www.expedia.ca/Hotel-Search?startDate=2025-11-02&endDate=2025-11-03&adults=2®ionId=2897) ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=900&h=336&p=1&q=high) ## Top Panama City Hotel Reviews ![JW Marriott Panama](//images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "Room service, clean room, excellent food" [](https://expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Hotel Riu Plaza Panama](//images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Beautiful hotel. Reasonably priced. " [](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Waldorf Astoria Panama](//images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "Absolutely fantastic experience. Beautiful property, wonderful staff, great food. Exceptional " [](https://expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![W Panama](//images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg) ### W Panama 10/10 Excellent "Nice clean property in a good area" [](https://expedia.ca/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Bristol Panama, a Registry Collection Hotel](//images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5_y.jpg) ### Bristol Panama, a Registry Collection Hotel 10/10 Excellent "Excelent atention to detail, recomended stay." [](https://expedia.ca/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) ## Find out more about Panama City ## Five Star Hotels in Panama City There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Panama City so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Panama City and get ready to be pampered like never before. #### Get a Great Deal on 5-Star Hotels in Panama City Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places. Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town. #### Make Your Escape to Panama City The results are in, and Panama City 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Panama City! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Panama City today and settle down in the lap of luxury tomorrow. ## Frequently asked questions ### What are the best 5-star hotels in Panama City? > Based on Expedia guest reviews, [Bristol Panama, a Registry Collection Hotel](https://www.expedia.ca/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information), [W Panama](https://www.expedia.ca/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) and [Hotel Riu Plaza Panama](https://www.expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) are among the most popular 5-star hotels in Panama City. Featuring top-quality amenities and excellent service, you'll enjoy a luxurious and memorable stay. ### How much does it cost to stay in a 5-star hotel in Panama City? > How much you pay for a 5-star hotel in Panama City depends on factors like when you plan to travel and the length of your break. A top tip for bagging the best deal? Use our pricing filters to check out all of the available options for your preferred dates. > > > > - Search for the lowest price per night from CA $179 ### What makes a hotel 5 stars in Panama City? > From gourmet dining venues and 24-hour gyms to swimming pools and premium bedding, the 5-star experience in Panama City is all about comfort and luxury. But it requires more than just top-notch conveniences to receive a 5-star rating. Stays must also deliver exceptional guest-focused services like in-room massages, on-site dry cleaning and laundry and a nightly turn-down service. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - [5 Star Hotels in Casco Viejo](https://www.expedia.ca/5Star-Casco-Viejo-Panama-City-Hotels.s50-n6285189-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Punta Pacifica](https://www.expedia.ca/5Star-Punta-Pacifica-Panama-City-Hotels.s50-n3000663482-0.Travel-Guide-Filter-Hotels) - [Hotels near Albrook Shopping Mall](https://www.expedia.ca/Albrook-Shopping-Mall-Hotels.0-l6159851-0.Travel-Guide-Filter-Hotels) - [Hotels near Avenida Balboa](https://www.expedia.ca/Avenida-Balboa-Hotels.0-l553248623453290531-0.Travel-Guide-Filter-Hotels) - [Barrio Chino Hotels](https://www.expedia.ca/Barrio-Chino-Panama-City-Hotels.0-n714749931894550528-0.Travel-Guide-Filter-Hotels) - [All Inclusive Resorts and in Bella Vista](https://www.expedia.ca/Bella-Vista-Panama-City-Hotels-All-Inclusive-Hotel.0-n3000663485-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - 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Gelabert Intl.](https://www.expedia.ca/Marcos-A-Gelabert-Intl-Airport-Hotels.0-aPAC-0.Travel-Guide-Filter-Hotels) - [Hotels near Metropolitan Cathedral of Panama](https://www.expedia.ca/Metropolitan-Cathedral-Of-Panama-Hotels.0-l6078477-0.Travel-Guide-Filter-Hotels) - [Hotels near Multiplaza Pacific Mall](https://www.expedia.ca/Multiplaza-Pacific-Mall-Hotels.0-l6158227-0.Travel-Guide-Filter-Hotels) - [Obarrio Hotels](https://www.expedia.ca/Obarrio-Panama-City-Hotels.0-n3000663487-0.Travel-Guide-Filter-Hotels) - [Hotels near Panama Canal Murals](https://www.expedia.ca/Panama-Canal-Murals-Hotels.0-l553248621532965255-0.Travel-Guide-Filter-Hotels) - [Hostels in Panamá Province](https://www.expedia.ca/Panama-Province-Hostels.d6246281-aaHostels.Travel-Guide-Accommodation) - [Rv Parks in Panamá Province](https://www.expedia.ca/Panama-Province-RV-Parks.d6246281-aaRVParks.Travel-Guide-Accommodation) - [Spa Hotels in Pueblo Nuevo](https://www.expedia.ca/Pueblo-Nuevo-Panama-City-Hotels-Spa-Hotel.0-n553248623199116148-0-tSpaHotel.Travel-Guide-Filter-Hotels) - [Pueblo Nuevo Hotels](https://www.expedia.ca/Pueblo-Nuevo-Panama-City-Hotels.0-n553248623199116148-0.Travel-Guide-Filter-Hotels) - [Punta Pacifica Hotels](https://www.expedia.ca/Punta-Pacifica-Panama-City-Hotels.0-n3000663482-0.Travel-Guide-Filter-Hotels) - [All Inclusive Resorts and in Punta Paitilla](https://www.expedia.ca/Punta-Paitilla-Panama-City-Hotels-All-Inclusive-Hotel.0-n6285983-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Punta Paitilla](https://www.expedia.ca/Punta-Paitilla-Panama-City-Hotels-Beach-Hotel.0-n6285983-0-tBeachHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Punta Paitilla](https://www.expedia.ca/Punta-Paitilla-Panama-City-Hotels-Luxury-Hotel.0-n6285983-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Punta Paitilla](https://www.expedia.ca/Punta-Paitilla-Panama-City-Hotels-Oceanfront-Hotels.0-n6285983-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Punta Paitilla Hotels](https://www.expedia.ca/Punta-Paitilla-Panama-City-Hotels.0-n6285983-0.Travel-Guide-Filter-Hotels) - [San Felipe Hotels](https://www.expedia.ca/San-Felipe-Panama-City-Hotels.0-n829297728598073344-0.Travel-Guide-Filter-Hotels) - [San Francisco Hotels](https://www.expedia.ca/San-Francisco-Panama-City-Hotels.0-n553248623199112076-0.Travel-Guide-Filter-Hotels) - [Santa Ana Hotels](https://www.expedia.ca/Santa-Ana-Panama-City-Hotels.0-n553248623199107606-0.Travel-Guide-Filter-Hotels) - [Hotels near Uruguay Street](https://www.expedia.ca/Uruguay-Street-Hotels.0-l6294103-0.Travel-Guide-Filter-Hotels) - [Hotels near Via Espana](https://www.expedia.ca/Via-Espana-Hotels.0-l6125940-0.Travel-Guide-Filter-Hotels) - [Flights to Panamá Province](https://www.expedia.ca/Destinations-In-Panama-Province.d6246281.Flight-Destinations) - [Flights from Marcos A. Gelabert Intl.](https://www.expedia.ca/lp/airports/pac/flights-from-marcos-a-gelabert-intl-airport) - [Flights from Bocas del Toro (BOC) to Panama City (PAC)](https://www.expedia.ca/lp/flights/boc/pac/bocas-del-toro-to-panama-city) - [Flights from Changuinola (CHX) to Panama City (PAC)](https://www.expedia.ca/lp/flights/chx/pac/changuinola-to-panama-city) - [Flights from Mexico City (MEX) to Panama City (PAC)](https://www.expedia.ca/lp/flights/mex/pac/mexico-city-to-panama-city) - [Flights from Merida (MID) to Panama City (PAC)](https://www.expedia.ca/lp/flights/mid/pac/merida-to-panama-city) - [Flights from Mamfe (MMF) to Panama City (PAC)](https://www.expedia.ca/lp/flights/mmf/pac/mamfe-to-panama-city) - [Flights from Panama City (PTY) to Panama City (PAC)](https://www.expedia.ca/lp/flights/pty/pac/panama-city-to-panama-city) - [Flights from Puerto Vallarta (PVR) to Panama City (PAC)](https://www.expedia.ca/lp/flights/pvr/pac/puerto-vallarta-to-panama-city) - [Flights from Rio Hato (RIH) to Panama City (PAC)](https://www.expedia.ca/lp/flights/rih/pac/rio-hato-to-panama-city) - [Flights from Tambor (TMU) to Panama City (PAC)](https://www.expedia.ca/lp/flights/tmu/pac/tambor-to-panama-city) - [Flights from Edmonton (YEG) to Panama City (PAC)](https://www.expedia.ca/lp/flights/yeg/pac/edmonton-to-panama-city) - [Flights from Montreal (YUL) to Panama City (PAC)](https://www.expedia.ca/lp/flights/yul/pac/montreal-to-panama-city) - [Flights from Vancouver (YVR) to Panama City (PAC)](https://www.expedia.ca/lp/flights/yvr/pac/vancouver-to-panama-city) - [Flights from Calgary (YYC) to Panama City (PAC)](https://www.expedia.ca/lp/flights/yyc/pac/calgary-to-panama-city) - [Flights from Toronto (YYZ) to Panama City (PAC)](https://www.expedia.ca/lp/flights/yyz/pac/toronto-to-panama-city) - [Albrook Shopping Mall](https://www.expedia.ca/Albrook-Shopping-Mall-Panama-City.d6159851.Vacation-Attraction) - [Avenida Balboa](https://www.expedia.ca/Avenida-Balboa-Calidonia.d553248623453290531.Vacation-Attraction) - [Cinta Costera](https://www.expedia.ca/Cinta-Costera-Calidonia.d6245970.Vacation-Attraction) - [Club de Clases y Tropas](https://www.expedia.ca/Club-De-Clases-Y-Tropas-Casco-Viejo.d553248621532965263.Vacation-Attraction) - [El Dorado Mall](https://www.expedia.ca/El-Dorado-Mall-Bethania.d553248621532963614.Vacation-Attraction) - [Metropolitan Nature Park](https://www.expedia.ca/Metropolitan-Nature-Park-Panama-City.d6078485.Vacation-Attraction) - [Multiplaza Pacific Mall](https://www.expedia.ca/Multiplaza-Pacific-Mall-San-Francisco.d6158227.Vacation-Attraction) - [Omar Torrijos Recreational Park](https://www.expedia.ca/Omar-Torrijos-Recreational-Park-San-Francisco.d553248621532964848.Vacation-Attraction) - [Visit Bella Vista](https://www.expedia.ca/Panama-City-Bella-Vista.dx3000663485) - [Visit Calidonia](https://www.expedia.ca/Panama-City-Calidonia.dx3000663488) - [Visit Campo Alegre](https://www.expedia.ca/Panama-City-Campo-Alegre.dx553248635976397615) - [Visit Casco Viejo](https://www.expedia.ca/Panama-City-Casco-Viejo.dx6285189) - [Visit Curundu](https://www.expedia.ca/Panama-City-Curundu.dx553248623199107736) - [Visit El Cangrejo](https://www.expedia.ca/Panama-City-El-Cangrejo.dx6285972) - [Visit Marbella](https://www.expedia.ca/Panama-City-Marbella.dx3000663483) - [Visit Obarrio](https://www.expedia.ca/Panama-City-Obarrio.dx3000663487) - [Visit Punta Pacifica](https://www.expedia.ca/Panama-City-Punta-Pacifica.dx3000663482) - [Visit Punta Paitilla](https://www.expedia.ca/Panama-City-Punta-Paitilla.dx6285983) - [Visit San Francisco](https://www.expedia.ca/Panama-City-San-Francisco.dx553248623199112076) - [Panamá Province Vacations](https://www.expedia.ca/Panama-Province.d6246281.Destination-Travel-Guides) - [Visit Panamá Province](https://www.expedia.ca/Panama-Province.dx6246281) - [Uruguay Street](https://www.expedia.ca/Uruguay-Street-Bella-Vista.d6294103.Vacation-Attraction) - [Car rentals near Albrook Shopping Mall](https://www.expedia.ca/Car-Rentals-In-Albrook-Shopping-Mall.d6159851.Car-Rental-Guide) - [Car rentals near Panama Canal Murals](https://www.expedia.ca/Car-Rentals-In-Panama-Canal-Murals.d553248621532965255.Car-Rental-Guide) - [Car rentals near Uruguay Street](https://www.expedia.ca/Car-Rentals-In-Uruguay-Street.d6294103.Car-Rental-Guide) - [Panamá Province Vacation Rentals](https://www.expedia.ca/Destinations-In-Panama-Province.d6246281.Vacation-Rental-Destinations)