Title: 10 Best Hotels in Santa Ana, Panama City for 2026 | Expedia.ca [Vacation Rentals in Panama City](https://expedia.ca/Panama-City-Vacation-Rentals.d2897.Travel-Guide-VacationRentals)[Flights to Panama City](https://expedia.ca/Cheap-Flights-To-Panama-City.d2897.Travel-Guide-Flights)[Things to do in Panama City](https://expedia.ca/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities)[Santa Ana Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Ana.d553248623199107606.Car-Rental-Guide)[Santa Ana Vacations](https://expedia.ca/Santa-Ana.d553248623199107606.Destination-Travel-Guides) ![Plaza Santa Ana, Panama Casco Viejo](https://images.trvl-media.com/place/553248623199107606/b6ad0470-c1f6-4b60-92c8-74bd8158bfc9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248623199107606/b6ad0470-c1f6-4b60-92c8-74bd8158bfc9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 15 - Mar 16](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2026-03-15&endDate=2026-03-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 16 - Mar 17](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2026-03-16&endDate=2026-03-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Santa Ana hotels ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/4a38aa01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, 1 Double Bed](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/c38aaf6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/3e5ecf32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/9c2266b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hostal La Cigarra [](https://www.expedia.ca/Panama-City-Hotels-Hostal-La-Cigarra.h87396713.Hotel-Information) Santa Ana 7.6/10 Good (65 reviews) "Excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) David CA $35 CA $39 total includes taxes & fees Mar 17 - Mar 18 [](https://www.expedia.ca/Panama-City-Hotels-Hostal-La-Cigarra.h87396713.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/90cd7d94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/f0903154.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Double Room Single Use](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/4cc4446a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/67d4e119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ART CASCO The Hotel [](https://www.expedia.ca/Panama-City-Hotels-ART-CASCO-The-Hotel.h89836824.Hotel-Information) Santa Ana 6.0/10 (11 reviews) "Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eldris CA $51 CA $56 total includes taxes & fees Mar 31 - Apr 1 [](https://www.expedia.ca/Panama-City-Hotels-ART-CASCO-The-Hotel.h89836824.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/w846h1318x0y4-5df5c378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/762cceb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (705) | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ba5a7e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casco View Apartments [](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) Santa Ana 9.0/10 Wonderful (78 reviews) "The space was very nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William CA $119 CA $172 total includes taxes & fees Mar 30 - Mar 31 [](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Double Room | View from room](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/77400971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/92156b5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/946c31e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/ce5bf1ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel República [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) Santa Ana 6.6/10 (187 reviews) "It's meant for a short stay, close to Casco Viejo and coast line. Clean bed and bathroom. Needs some maintenance. Beware, there's no hot water if that's a deal breaker for you." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mario CA $31 CA $35 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) ![Apartment (20)](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/dacdb94e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Apartment | Dining room](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/ef205966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (05) | Living area](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/679f386c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/7977bbcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Manzana by Wynwood House [](https://www.expedia.ca/Panama-City-Hotels-La-Manzana-By-Wynwood-House.h100572489.Hotel-Information) Santa Ana 7.2/10 Good (15 reviews) "Great hotel. Very close to Casco viejo" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LUCILA CA $87 CA $133 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Panama-City-Hotels-La-Manzana-By-Wynwood-House.h100572489.Hotel-Information) ![Room, Multiple Bedrooms, Accessible, Smoking | Exterior](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/1445b47d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Bedrooms, Accessible, Smoking | Exterior](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/5ee5555f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Bedrooms, Accessible, Smoking | Lounge](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/141773b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/w2042h1548x6y4-9f255786.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Room-sofa Bed Stay Rooftop Pool & Gym, A [](https://www.expedia.ca/Panama-City-Hotels-Room-In-Guest-Room-Sofa.h112906538.Hotel-Information) Santa Ana 2.0/10 (1 review) "You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cristian Camilo Betancur CA $178 CA $196 total includes taxes & fees Mar 18 - Mar 19 [](https://www.expedia.ca/Panama-City-Hotels-Room-In-Guest-Room-Sofa.h112906538.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/17000000/16590000/16580900/16580844/625b54fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Magnolia Number 10 | Balcony](https://images.trvl-media.com/lodging/17000000/16590000/16580900/16580844/0241a48d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/17000000/16590000/16580900/16580844/b86e38d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![French Rose Number 12 | Balcony](https://images.trvl-media.com/lodging/17000000/16590000/16580900/16580844/717365c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Taboga Palace Spa Hotel [](https://www.expedia.ca/Taboga-Hotels-Taboga-Palace-Spa-Hotel.h16580844.Hotel-Information) 17.7 km from Santa Ana 9.4/10 Exceptional (48 reviews) "My room was perfect just steps from the pool with a great view of the ocean. Dave was a great host and help make my stay truly enjoyable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James CA $178 CA $196 total includes taxes & fees Mar 17 - Mar 18 [](https://www.expedia.ca/Taboga-Hotels-Taboga-Palace-Spa-Hotel.h16580844.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/17000000/16280000/16271000/16270978/16b35949.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Suite, Sea View](https://images.trvl-media.com/lodging/17000000/16280000/16271000/16270978/d5edf799.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/17000000/16280000/16271000/16270978/92c9ca27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/17000000/16280000/16271000/16270978/25c339ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Caprichosa [](https://www.expedia.ca/Taboga-Hotels-Villa-Caprichosa.h16270978.Hotel-Information) 18.3 km from Santa Ana 9.8/10 Exceptional (55 reviews) "Nice view of the beach " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lourdes CA $309 CA $340 total includes taxes & fees Apr 6 - Apr 7 [](https://www.expedia.ca/Taboga-Hotels-Villa-Caprichosa.h16270978.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/bf18b63d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/98e777ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/1c70a5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room, 2 Double Beds, Ensuite, Ground Floor](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/de48ce4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Panama House Bed & Breakfast [](https://www.expedia.ca/Panama-City-Hotels-Panama-House-Bed-Breakfast.h11845091.Hotel-Information) Bella Vista, 4.6 km from Santa Ana 9.0/10 Wonderful (196 reviews) "Amenities, staff, cleanliness, price all excellent!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher CA $47 CA $52 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Panama-City-Hotels-Panama-House-Bed-Breakfast.h11845091.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/114000000/113560000/113553400/113553339/ca901e22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/114000000/113560000/113553400/113553339/06229a16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/114000000/113560000/113553400/113553339/68484199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/114000000/113560000/113553400/113553339/72d75b66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Résidence Panamá [](https://www.expedia.ca/Panama-City-Hotels-La-Residence-Panama.h113553339.Hotel-Information) Campo Alegre, 3.4 km from Santa Ana 9.2/10 Wonderful (7 reviews) "Mauricio and Edinson were the stars of the place... they were always extremely helpful... always cheerful and welling to get out of their way to make sure clients are content. 100% recommended. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) khaled CA $148 CA $163 total includes taxes & fees Mar 22 - Mar 23 [](https://www.expedia.ca/Panama-City-Hotels-La-Residence-Panama.h113553339.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/3000000/2230000/2227800/2227716/ba6d87f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/3000000/2230000/2227800/2227716/54e82931.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Airport shuttle](https://images.trvl-media.com/lodging/3000000/2230000/2227800/2227716/762ab2a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, international cuisine](https://images.trvl-media.com/lodging/3000000/2230000/2227800/2227716/2132d974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Montreal [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Montreal.h2227716.Hotel-Information) Bella Vista, 2.7 km from Santa Ana 6.0/10 (411 reviews) "The room was in good condition; the staff was very helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) VELVETT CA $35 CA $39 total includes taxes & fees Mar 17 - Mar 18 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Montreal.h2227716.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/68c712fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Room | Living area](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/edd11e34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Winery](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/921ce9a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/b8687db2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Plaza Herrera [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Herrera.h113477576.Hotel-Information) San Felipe, 0.7 km from Santa Ana 9.8/10 Exceptional (29 reviews) "Great location in walkable area of Casco Viejo. Helpful staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon CA $320 CA $354 total includes taxes & fees Mar 26 - Mar 27 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Herrera.h113477576.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/a4c743af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/deeb0964.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/49b75ad6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/d2ce5b0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Panama Centro Via Argentina [](https://www.expedia.ca/Panama-City-Hotels-Ramada-Panama-Centro-Via-Argentina.h10412883.Hotel-Information) El Cangrejo, 3.8 km from Santa Ana 7.4/10 Good (314 reviews) "nice central access to the whole Panama City and convenient price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose CA $117 CA $128 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Panama-City-Hotels-Ramada-Panama-Centro-Via-Argentina.h10412883.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/5000000/4630000/4624400/4624380/a1ed65f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/5000000/4630000/4624400/4624380/31671e8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![King Room - Disability Acces](https://images.trvl-media.com/lodging/5000000/4630000/4624400/4624380/d4f6de92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Studio, 1 King Bed with Sofa bed, Balcony | Balcony](https://images.trvl-media.com/lodging/5000000/4630000/4624400/4624380/6c8d5508.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel y Casino Central Park Panama [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Y-Casino-Central-Park-Panama.h4624380.Hotel-Information) Bethania, 5.6 km from Santa Ana 7.6/10 Good (442 reviews) "Great service, clean, great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) EDGAR CA $78 CA $86 total includes taxes & fees Mar 27 - Mar 28 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Y-Casino-Central-Park-Panama.h4624380.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4620000/4616300/4616247/505c9cd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Single Room, 1 King Bed](https://images.trvl-media.com/lodging/5000000/4620000/4616300/4616247/d3e08235.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast served](https://images.trvl-media.com/lodging/5000000/4620000/4616300/4616247/d6cc3141.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/5000000/4620000/4616300/4616247/0f21996a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Toscana Inn [](https://www.expedia.ca/Panama-City-Hotels-Toscana-Inn.h4616247.Hotel-Information) El Cangrejo, 3.7 km from Santa Ana 8.8/10 Excellent (744 reviews) "Room was clean, bed comfortable but minimal amenities provided. Breakfast was basic however it served the need and price was good. Location perfect for convenience to transport, restaurants and shopping. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Merle CA $119 CA $132 total includes taxes & fees Mar 18 - Mar 19 [](https://www.expedia.ca/Panama-City-Hotels-Toscana-Inn.h4616247.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/890400/890364/4bd8a8dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/900000/890400/890364/b96a76c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/890400/890364/54ff0574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/900000/890400/890364/e89e5bba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza Panama by IHG [](https://www.expedia.ca/Panama-City-Hotels-Crowne-Plaza-Panama.h890364.Hotel-Information) Bella Vista, 3.2 km from Santa Ana 8.0/10 Very good (227 reviews) "Staff were amazing . Great breakfast and convenient area close to the train station " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darius CA $141 CA $155 total includes taxes & fees Mar 21 - Mar 22 [](https://www.expedia.ca/Panama-City-Hotels-Crowne-Plaza-Panama.h890364.Hotel-Information) ![Spa](https://images.trvl-media.com/lodging/6000000/5220000/5219200/5219140/86639a0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5220000/5219200/5219140/03492eb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5220000/5219200/5219140/6ebf10a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (PAB 18 per person)](https://images.trvl-media.com/lodging/6000000/5220000/5219200/5219140/16c5b512.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Panama City Downtown, Panama [](https://www.expedia.ca/Panama-City-Hotels-Hilton-Garden-Inn-Panama-City-Downtown.h5219140.Hotel-Information) El Cangrejo, 3.4 km from Santa Ana 8.6/10 Excellent (1,003 reviews) "Staff very friendly. Good breakfast. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Liam CA $118 CA $130 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Panama-City-Hotels-Hilton-Garden-Inn-Panama-City-Downtown.h5219140.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/91000000/90810000/90801900/90801879/b662a355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/91000000/90810000/90801900/90801879/7b798faa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/91000000/90810000/90801900/90801879/9c609bea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/91000000/90810000/90801900/90801879/e8703472.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MARINN PLACE Financial District [](https://www.expedia.ca/Panama-City-Hotels-MARINN-Place-Financial-Distrit.h90801879.Hotel-Information) Campo Alegre, 3.3 km from Santa Ana 9.0/10 Wonderful (321 reviews) "Yes" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) gerardo CA $119 CA $131 total includes taxes & fees Apr 8 - Apr 9 [](https://www.expedia.ca/Panama-City-Hotels-MARINN-Place-Financial-Distrit.h90801879.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/45000000/44130000/44123200/44123136/e5437b2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/45000000/44130000/44123200/44123136/850ba6b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, laptop workspace, soundproofing, free WiFi](https://images.trvl-media.com/lodging/45000000/44130000/44123200/44123136/4f8ea47c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/45000000/44130000/44123200/44123136/ae359013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gran Evenia Panama [](https://www.expedia.ca/Panama-City-Hotels-Gran-Evenia-Panama.h44123136.Hotel-Information) El Cangrejo, 3.8 km from Santa Ana 9.2/10 Wonderful (223 reviews) "room was clean, staff was great, the wi-Fi works good and the breakfast was a little fresh but nothing that a little salt cant fix" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shantel CA $204 CA $227 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Panama-City-Hotels-Gran-Evenia-Panama.h44123136.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/1012405e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 2 Double Beds | Living area](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/871ef81e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/03c049bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Apartment | View from room](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/1b369fc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Torres de Alba Hotel & Suites [](https://www.expedia.ca/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) El Cangrejo, 3.4 km from Santa Ana 8.8/10 Excellent (522 reviews) "Very clean and amazing stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reinaldo CA $127 CA $140 total includes taxes & fees Mar 17 - Mar 18 [](https://www.expedia.ca/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-30&endDate=2026-03-31®ionId=553248623199107606&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Santa Ana Find the best Santa Ana areas and neighborhoods for the activities you enjoy most. - Casco Viejo - Bella Vista - El Cangrejo - San Francisco - San Felipe ![Panama City view old casco viejo antiguo](https://images.trvl-media.com/place/6285189/2d543e5b-dc8c-4a1e-9872-eb2afab3bfc9.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![#ciudaddepanama](https://images.trvl-media.com/place/2897/03378482-6fa2-4594-96ce-513a22a4250a.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Hideki Yamagata ![You can find Simon Boliva statue in most Latin America countries ](https://images.trvl-media.com/place/2897/fefd5676-1a9e-4e1c-80d1-a091935f3d74.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Botak Jon ![A good contrast, modern high rise behind and colonial houses in front ](https://images.trvl-media.com/place/2897/4c35bf40-b641-4f9b-89ba-fd0b28f2788d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Botak Jon ![Nice place to walk around here](https://images.trvl-media.com/place/2897/c5bfc50a-faf0-4497-80c7-103bab605406.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Botak Jon [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6285189) ![Casco Viejo map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:w%7Csu%40z%7CmdNsAsJNa%40sCsD%60HKJ%7DFO_Ai%40A%3F%5B%5C%3FBmAXC%7D%40aBd%40yBj%40%3FB%7D%40b%40%40Nl%40t%40I%60%40uA%7C%40D%40r%40%7ECNNm%40%60AIaAAVoCbFdAjB%7B%40pEvAKn%40_J%7CB%3FzDt%40%3FHnDZCKl%40f%40bAq%40r%40GrApAFQrAlBp%40O%7EBgEY%5CrCr%40%5EVxAiSFmDpA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=uEe2tFISgoY2i6D1L7Cp-Szzr7E=) ### Casco Viejo Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6285189) ![Nice building, highlight on Panama's skyline.](https://images.trvl-media.com/place/2897/e7a58ce8-b6f0-462e-9d0a-c00e40ae732b.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by My World ![#aboveitall](https://images.trvl-media.com/place/2897/bfaeea70-86e7-4f1f-82e7-58c757650d86.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Freddy Dominguez ![Old meets new](https://images.trvl-media.com/place/2897/fd510f83-463e-4e76-bf4b-a18c3454a601.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Journey Of A Nomadic Family ![The F&F Tower 242,9m (previously known as the Revolution Tower) is an office tower in Panama City. Emporis selected the F&F Tower among the top 10 best skyscrapers of the year in 2011, ranking it 7th out of the 10 Emporis Skyscraper Award winners for its architectural excellence regarding the design of building and its functionality. It is also one of the most iconic buildings of Panama City. #tower #revolutiontower #spiral #spiraltower](https://images.trvl-media.com/place/2897/3edf9c75-3949-41fd-b2bd-528cc7de3979.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Adrian Damian ![Summer time in Panama City, blue sky and sunny days to enjoy this city. #lifeatexpedia #PanamaCity #travel](https://images.trvl-media.com/place/2897/62672ebb-ab68-4df6-9850-2c73cf428908.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Fabiola Tile [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=3000663485) ![Bella Vista map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ksxu%40xrmdNeY_Ea%60Ach%40wd%40eZ%60AmN%60KeE%7EE%7DIvIw%40bC%7BFvJkEf%40cEx%5BaVbHnA%7CGrN%60HxCfGnFlD_AhLfHlHj%40%60EiErGh%40tIfx%40qFbFoH%7Cc%40aI_BsItR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=kybUo6TOAHV5XfFCWEb1fcek5LQ=) ### Bella Vista Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. [See properties](https://www.expedia.ca/Hotel-Search?regionId=3000663485) ![Panama City Old Town streets and buildings](https://images.trvl-media.com/place/6285972/af7e9b24-0964-44fc-86b9-7efe328f4d40.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6285972) ![El Cangrejo map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7Bpzu%40%60xldN%7D%5BcRdDeKmFiDvDaNbCgGxW%7D%40rIrDpFzGvJpGwFlIpFnGg%60%40zR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=TyMwYMNUwH4f3VdmHvCgBWau0RI=) ### El Cangrejo The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6285972) ![The Bridge of the Americas in summer, Panama City](https://images.trvl-media.com/place/553248623199112076/b14d4c65-cc25-49b4-aad3-c708d5b994fc.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![La entrada a la Ciudad de Panamá ](https://images.trvl-media.com/place/2897/df27e517-e0be-4550-bc06-92be5954aac5.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Karla Jimenez ![Hard Rock Hotel Panama #StunningStructures](https://images.trvl-media.com/place/2897/295f53ea-71ed-49f8-9430-8d4fd3fac6c7.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Adrian Damian ![Panama #StunningStructures](https://images.trvl-media.com/place/2897/bcdd62da-f297-44f7-93bd-f5423e81a7d2.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Adrian Damian ![#StunningStructures impressive view of Panama City from Hardrock Hotel Megapolis](https://images.trvl-media.com/place/2897/6084884e-9927-4c00-865b-1ba27cd82b32.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Adrian Damian [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248623199112076) ![San Francisco map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wr%7Bu%40hdjdNiV%7BDud%40_SiCcEAqJ%7B%40aEkW_Zh%5EeK%7E%40_CWkNbDFxD%7BAgA%7BEqBqDL%7DDwDoKIkCt%40sBsAgAo%40oBvCKhG%7EDhBFh%40i%40%7C%40CxAx%40zCZrEu%40lA%7D%40So%40b%40qChA%7D%40dCAtExD%60DrGvCxArDQMwDvBWl%40y%40rAJo%40w%40z%40_AxCrBtBn%40pEpD%7BBlCmAyAt%40dEb%40Nd%40e%40HaAzBkCnFfDFr%40%7B%40h%40Jr%40pIvFlFdL%7EJlJhM%60SlDPbe%40eBrBlAr%40xAA%60AsAtBaFnBO%60%40p%40bEQtF%60HxAi%40lAIoA%7DEQCXz%40VoATQdAn%40p%40lH%40xBrBh%40xBK%60ArAVh%40%7EAvAd%40jD%7ECXjAYhE%5E%5CdBKnAnA_EzD%7BDp%40kBkAyFy%40qAdAqC%5Ec%40b%40yBYuBXaEtDeFi%40qC%7B%40kHiFgAKgBn%40eAE_ByBuEaDcCk%40kAyA_GuMaDB_DiB_A%7CAsFrB%7D%40jEiGjCeDVQfC%7BBx%40HrB%5DhAsIfEgBbE&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=LnVVpfxBpjhgnoVjOyo-4O6-uto=) ### San Francisco San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50\. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248623199112076) ![Balcony of a colonial house, Casco Viejo, Panama City, Panama, Central America](https://images.trvl-media.com/place/829297728598073344/b153dfc8-01d6-40ec-9e98-642d0f1b8062.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![#ciudaddepanama](https://images.trvl-media.com/place/2897/03378482-6fa2-4594-96ce-513a22a4250a.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Hideki Yamagata ![A good contrast, modern high rise behind and colonial houses in front ](https://images.trvl-media.com/place/2897/4c35bf40-b641-4f9b-89ba-fd0b28f2788d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Botak Jon ![Nice place to walk around here](https://images.trvl-media.com/place/2897/c5bfc50a-faf0-4497-80c7-103bab605406.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Botak Jon ![You can find Simon Boliva statue in most Latin America countries ](https://images.trvl-media.com/place/2897/fefd5676-1a9e-4e1c-80d1-a091935f3d74.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Botak Jon [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=829297728598073344) ![San Felipe map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:w%7Csu%40z%7CmdNsAsJNa%40sCsD%60HKJ%7DFO_Ai%40A%3F%5B%5C%3FBmAXC%7D%40aBd%40yBj%40%3FB%7D%40b%40%40Nl%40t%40I%60%40uA%7C%40D%40r%40%7ECNNm%40%60AIaAAVoCbFdAjB%7B%40pEvAKn%40_J%7CB%3FzDt%40%3FHnDZCKl%40f%40bAq%40r%40GrApAFQrAlBp%40O%7EBgEY%5CrCr%40%5EVxAiSFmDpA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=uEe2tFISgoY2i6D1L7Cp-Szzr7E=) ### San Felipe If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing. [See properties](https://www.expedia.ca/Hotel-Search?regionId=829297728598073344) ## Top Santa Ana Hotel Reviews ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/d26cb29b_y.jpg) ### Marriott Panama Hotel 8/10 Good "We stay for only one night. Our experience was good. The breakfast included was really good. " [](https://expedia.ca/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Polite staff, large rooms and nice coffee shop" [](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 8/10 Good "Comfortable beds and clean rooms " [](https://expedia.ca/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/a1c4d702_y.jpg) ### Waymore Hotel Spa & Casino 8/10 Good "Breakfast buffet was very disappointing! Eggs and other dishes barely edible! Do better!" [](https://expedia.ca/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961_y.jpg) ### Sheraton Grand Panama 6/10 Okay "The ceiling in the bathroom was leaking whenever someone took a shower. Phone didn’t work in the room for 3 first three days. Complain about it. And they fixed it after the 3rd day. " [](https://expedia.ca/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Hotel Ojos del Rio](https://images.trvl-media.com/lodging/11000000/10540000/10538500/10538417/dddd2643_y.jpg) ### Hotel Ojos del Rio 10/10 Excellent "The hotel needs a swimming pool." [](https://expedia.ca/Panama-City-Hotels-Hotel-Ojos-Del-Rio.h10538417.Hotel-Information) ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/7dd302e1_y.jpg) ### Courtyard by Marriott Panama Multiplaza Mall 10/10 Excellent "Friendly staff and great location. " [](https://expedia.ca/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "Yes we had a wonderful stay. The view of the ocean, pool, & Panama City across the water was excellent from a lovely big balcony. The buffet breakfast was EXCELLENT. Taxis at the ready & cheap to take us anywhere we wished. Staff wonderful Michelle at the pool area, Nelino at the breakfast - in fact all staff very friendly & helpful. Would definitely recommend this hotel." [](https://expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Excellent hotel, perfect location and the staff incredibly welcoming." [](https://expedia.ca/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ## Find out more about Santa Ana ### Top reasons to visit Santa Ana - **Historical Attractions:** Visit significant sites like the Santa Ana Church and Iglesia Santa Ana to experience the rich cultural heritage of the area. - **Charming Walking Tours:** Enjoy guided walking tours led by locals, showcasing the unique charm and highlights of Santa Ana. - **Relaxing Green Spaces:** Spend time at Santa Ana Square, a perfect spot for relaxation and enjoying scenic views. - **Diverse Accommodations:** Choose from a wide range of lodging options, from budget to luxury, catering to all types of travelers. - **Proximity to Attractions:** Easily access nearby popular attractions like Casco Viejo and Parque Natural Metropolitano for day trips. ### Find great hotels near Santa Ana Santa Ana boasts a diverse selection of accommodations, catering to every traveler's needs, from budget-friendly lodgings to luxurious 5-star hotels. Whether you're seeking a charming lodge or a modern hotel, you'll find options that provide essential services for city exploration, business trips, or a pet-friendly getaway. Discover the best hotels in Santa Ana and enjoy a memorable stay in the heart of Panama City. - **[Central Hotel Panama Casco Viejo:](https://www.expedia.ca/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information)** Nestled in the vibrant Casco Viejo district, Central Hotel Panama offers a romantic and luxurious environment perfect for couples and business travellers alike. This 4-star gem is renowned for its exceptional spa services, featuring a full-service spa, steam room, and facial treatments to soothe your senses. With a strong focus on romance, guests can indulge in packages that include champagne service and 24-hour room service. For business needs, the hotel provides accessible meeting rooms and conference spaces, ensuring a seamless experience for professionals. - **[American Trade Hotel:](https://www.expedia.ca/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information)** Located in the heart of Panama City, the American Trade Hotel blends adventure, family-friendly amenities, and romantic touches into a unique lodging experience. This 4.5-star hotel boasts proximity to outdoor activities such as biking, hiking, and even Segway rentals, making it ideal for adventurous families. Guests can enjoy garden views from the restaurant while savouring limited-hour room service and champagne service. The outdoor pool area, complete with sun loungers and in-room massage options, provides a relaxing retreat for couples seeking a romantic getaway. - **Sofitel Legend Casco Viejo, Panama City:** This 5-star luxury hotel embodies elegance and sophistication in the historic Casco Viejo area. With a strong emphasis on business and leisure, it offers accessible business centres and comprehensive facilities for corporate travellers. Guests can unwind at the spa, which features treatment rooms and a swim-up bar, perfect for relaxation after a busy day. The hotel's exquisite design and top-notch services make it a premier choice for discerning travellers looking for an unforgettable experience in Panama City. ### Where to stay near Santa Ana Santa Ana, a vibrant neighbourhood in Panama City, offers a delightful mix of family-friendly activities and historical charm. Explore the bustling streets filled with friendly locals, and immerse yourself in the unique atmosphere of Panama's capital. Nearby, attractions like the historic Casco Viejo and the scenic Parque Natural Metropolitano provide perfect day trips. Whether you’re seeking a city-themed adventure or a relaxing family holiday, Santa Ana is an ideal base for discovering the rich culture of Panamá Province. - **[Panama City:](https://www.expedia.ca/Panama-City-Hotels.d2897.Travel-Guide-Hotels)** As the vibrant capital of Panama, Panama City is a bustling metropolis rich in culture and history. Nestled in the heart of the country, it offers a diverse travel experience, appealing to families, business travellers, and city explorers alike. The city showcases a stunning mix of modern skyscrapers and colonial architecture. Visitors can enjoy shopping at prominent centres and malls, while the nearby beaches, parks, and lively streets invite exploration and relaxation. With visitor numbers peaking in January, July, and September, it's an ideal destination year-round. - **[Casco Viejo:](https://www.expedia.ca/Casco-Viejo-Panama-City-Hotels.0-n6285189-0.Travel-Guide-Filter-Hotels)** Located a mere 644m from Santa Ana, Casco Viejo is a UNESCO World Heritage site known for its charming cobblestone streets and historic buildings. This neighbourhood is a hub of activity, making it perfect for families and city adventurers. With vibrant shopping centres, resorts, and delightful dining options, Casco Viejo is a picturesque setting for exploration. Enjoy the nearby beaches and parks, as well as the unique street life that adds to its cultural richness. Peak visitor months include January and March to April, offering a lively atmosphere. - **[San Felipe:](https://www.expedia.ca/San-Felipe-Panama-City-Hotels.0-n829297728598073344-0.Travel-Guide-Filter-Hotels)** Also situated 644m away from Santa Ana, San Felipe is a captivating neighbourhood known for its historic significance and charming streets. This area attracts families, business travellers, and city explorers, offering a mix of shopping malls and local boutiques. Visitors can explore the nearby beaches, historic places, and monuments that tell the story of Panama's past. With peak tourist arrivals from December to February, San Felipe provides a vibrant yet tranquil atmosphere for a memorable vacation. ### Things to do near Santa Ana Santa Ana, a vibrant neighbourhood in Panama City, is perfect for family and business vacations. Visitors can enjoy a variety of activities, including exploring shopping malls and unique shopping areas. Don't miss the chance to embark on a walking tour of Santa Ana, guided by knowledgeable locals, to discover touristy spots and enjoy pleasant strolls through this charming district. **Shopping** In Santa Ana, you can visit Avenida Central, located 483m away, offering a vibrant mix of family-friendly shops and entertainment. Albrook Shopping Mall, just 1.6km away, is perfect for family outings. If you're up for a drive, check out Uruguay Street, located 3.2km away, for more local shopping experiences. **Recreation** Experience the vibrant atmosphere at [Maracana Stadium](https://www.expedia.ca/Maracana-Stadium-Hotels.0-l553248621562725885-0.Travel-Guide-Filter-Hotels), located 1.3km from Santa Ana, perfect for sports enthusiasts. For an exhilarating outing, head to Estadio Nacional Rod Carew, 9.7km away, or Estadio Rommel Fernandez, 11.3km away, both offering thrilling sports events and energetic vibes. **Adventure** Embark on the Honeycreeper Ridge Trail, located 211.3km from Santa Ana, for a scenic hike surrounded by vibrant nature. For a thrilling experience, visit Gatun Eco Adventures, situated 48.3km away, where you can soar through the treetops on an exhilarating zipline ropes course. **Nightlife** Experience the vibrant nightlife in Santa Ana by visiting Crown Casino, just 3.2km away, for thrilling games and romance. For a cultural evening, enjoy a show at the National Theater (0.9.7km away) or Anita Villalaz Theater (1.3km away), both offering family-friendly entertainment and a romantic atmosphere. ### Booking tips and Expedia advantages for Santa Ana When visiting Santa Ana, Panama, consider exploring free attractions like Albrook Shopping Mall and Cinta Costera. To save on accommodation, travel during the off-peak months from September to November, when prices are lower compared to peak times like March and December to January. Tuesdays are typically the cheapest days to stay, while Saturdays are the most expensive. Use Expedia to compare prices and book packages that combine flights and hotels for added savings. Don't forget to filter for eco-certified hotels to find sustainable options that fit your budget. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay around Santa Ana are September to November, where the prices are slightly lower. This is in comparison to March and December to January, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay around Santa Ana is Tuesday. The most expensive day to stay around Santa Ana is Saturday. - **Find cheap hotels on Expedia:** Expedia’s search tool enables you to choose your budget, preferred location, and additional criteria. You can easily sort your results to display prices from lowest to highest, allowing you to find the most affordable hotels right away. Additionally, you can refine your choices by hotel type—select the "Eco-certified" filter to discover sustainable and environmentally-friendly accommodations available for booking. - **Consider bundling your trip:** You can save money by combining your Santa Ana hotel reservation with your flights and activities when you book an Expedia package. ### Find the best attractions near Santa Ana Santa Ana, located in Panama City, is perfect for family and business vacations, offering a rich cultural experience. Visitors can explore historical sites such as the Santa Ana Church and Iglesia Santa Ana, relax at Santa Ana Square, and enjoy scenic views near the canyon. The area's attractions cater to those seeking a blend of history and city life, making it an ideal destination for tourists looking to immerse themselves in local culture. - **[Metropolitan Cathedral of Panama:](https://www.expedia.ca/Metropolitan-Cathedral-Of-Panama-Hotels.0-l6078477-0.Travel-Guide-Filter-Hotels)** Located 805m from Santa Ana, this stunning cathedral showcases remarkable colonial architecture and intricate artwork. It serves as a cultural hub, offering a glimpse into Panama's rich history and religious heritage. - **Ancon Hill:** Just 966m from Santa Ana, Ancon Hill provides breathtaking panoramic views of Panama City and the Panama Canal. This outdoor oasis is perfect for hiking and enjoying nature while immersing yourself in the area's scenic beauty. - **Interoceanic Canal Museum:** Situated 805m away, this museum is dedicated to the history of the Panama Canal. It features fascinating exhibits that highlight the canal's significance, making it a must-visit for culture enthusiasts. ### Best time to go to Santa Ana Visitor numbers around Santa Ana is generally unchanged in popularity throughout the year. The best time to visit Santa Ana can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santa Ana falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around Santa Ana falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain. | **![calendar icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly cloudy icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation rate icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------- | --------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------ | ------------------------------------------------------------------------------------------------------------------ | | January | 78.8°F (26.0°C) | No Rain (Dry) | Mostly Sunny | Slightly High | Slightly High | | February | 79.2°F (26.2°C) | No Rain (Dry) | Mostly Sunny | Slightly High | Average | | March | 79.7°F (26.5°C) | No Rain (Dry) | Mostly Sunny | Average | Slightly High | | April | 80.4°F (26.9°C) | Light Rain | Mostly Sunny | Average | Average | | May | 80.2°F (26.8°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Average | | June | 79.9°F (26.6°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Average | | July | 79.3°F (26.3°C) | Frequent Rain | Mostly Cloudy | Average | Average | | August | 79.2°F (26.2°C) | Frequent Rain | Mostly Cloudy | Average | Average | | September | 79.3°F (26.3°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Slightly Low | | October | 78.6°F (25.9°C) | Frequent Rain | Mostly Cloudy | Average | Slightly Low | | November | 78.3°F (25.7°C) | Frequent Rain | Mostly Cloudy | Average | Slightly Low | | December | 78.6°F (25.9°C) | Light Rain | Mostly Cloudy | Slightly High | Slightly High | ### The nearest major airports for your trip to Santa Ana When visiting Santa Ana, you have convenient access to two major airports. Panama City ([PTY](https://www.expedia.ca/Tocumen-Intl-Airport-Hotels.0-aPTY-0.Travel-Guide-Filter-Hotels)\-Tocumen Intl.) is located 20.9km away, with notable hotels like [The Santa Maria](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information), A Luxury Collection Hotel & Golf Resort, 8.0km from the airport, and [JW Marriott Panama](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information), 16.1km away. Alternatively, Panama City ([PAC](https://www.expedia.ca/Marcos-A-Gelabert-Intl-Airport-Hotels.0-aPAC-0.Travel-Guide-Filter-Hotels)\-Marcos A. Gelabert Intl.) is only 3.2km from Santa Ana, featuring excellent accommodations such as [Waldorf Astoria Panama](https://www.expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information), just 3.2km away, and [Hilton Panama](https://www.expedia.ca/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information), 4.8km away. Transportation services from these hotels to the airports typically include on-request shuttle services, offering ease and comfort for your travel needs. ## Frequently asked questions ### What are the best budget hotels in Santa Ana? > For those seeking a luxurious experience without breaking the bank, [Hotel República](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) presents a charming option with its rooftop terrace providing partial ocean views, superb for relaxing after a day of adventures. This hotel also features free WiFi and air conditioning, ensuring comfort during your stay. Families can take advantage of the area shuttle service to explore Panama City's attractions conveniently. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa Ana hotel booking with Expedia? ### How much is the nightly rate at a Santa Ana hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - [5 Star Hotels in Casco Viejo ](https://www.expedia.ca/5Star-Casco-Viejo-Panama-City-Hotels.s50-n6285189-0.Travel-Guide-Filter-Hotels) - [Hotels near Albrook Shopping Mall ](https://www.expedia.ca/Albrook-Shopping-Mall-Hotels.0-l6159851-0.Travel-Guide-Filter-Hotels) - [Amador Hotels ](https://www.expedia.ca/Amador-Panama-City-Hotels.0-n553248635933392377-0.Travel-Guide-Filter-Hotels) - [Hotels near Avenida Balboa ](https://www.expedia.ca/Avenida-Balboa-Hotels.0-l553248623453290531-0.Travel-Guide-Filter-Hotels) - [Balboa Hotels ](https://www.expedia.ca/Balboa-Panama-City-Hotels.0-n6323179-0.Travel-Guide-Filter-Hotels) - 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[Flights from Toronto (YYZ) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yyz/pac/toronto-to-panama-city) - [Albrook Shopping Mall ](https://www.expedia.ca/Albrook-Shopping-Mall-Panama-City.d6159851.Vacation-Attraction) - [Cinta Costera ](https://www.expedia.ca/Cinta-Costera-Calidonia.d6245970.Vacation-Attraction) - [Club de Clases y Tropas ](https://www.expedia.ca/Club-De-Clases-Y-Tropas-Casco-Viejo.d553248621532965263.Vacation-Attraction) - [Maracana Stadium ](https://www.expedia.ca/Maracana-Stadium-El-Chorrillo.d553248621562725885.Vacation-Attraction) - [Visit Balboa ](https://www.expedia.ca/Panama-City-Balboa.dx6323179) - [Visit Calidonia ](https://www.expedia.ca/Panama-City-Calidonia.dx3000663488) - [Visit Casco Viejo ](https://www.expedia.ca/Panama-City-Casco-Viejo.dx6285189) - [Visit Curundu ](https://www.expedia.ca/Panama-City-Curundu.dx553248623199107736) - [Visit El Chorrillo ](https://www.expedia.ca/Panama-City-El-Chorrillo.dx553248623199107689) - [Panamá Province Vacations ](https://www.expedia.ca/Panama-Province.d6246281.Destination-Travel-Guides) - [Visit Panamá Province ](https://www.expedia.ca/Panama-Province.dx6246281) - [Car rentals near Albrook Shopping Mall ](https://www.expedia.ca/Car-Rentals-In-Albrook-Shopping-Mall.d6159851.Car-Rental-Guide) - [Car rentals near Balboa ](https://www.expedia.ca/Car-Rentals-In-Balboa.d6323179.Car-Rental-Guide) - [Panamá Province Vacation Rentals ](https://www.expedia.ca/Destinations-In-Panama-Province.d6246281.Vacation-Rental-Destinations)