Title: 10 Best Hotels in Santa Ana, Panama City for 2026 | Expedia.ca [Vacation Rentals in Panama City](https://expedia.ca/Panama-City-Vacation-Rentals.d2897.Travel-Guide-VacationRentals)[Flights to Panama City](https://expedia.ca/Cheap-Flights-To-Panama-City.d2897.Travel-Guide-Flights)[Things to do in Panama City](https://expedia.ca/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities)[Santa Ana Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Ana.d553248623199107606.Car-Rental-Guide)[Santa Ana Vacations](https://expedia.ca/Santa-Ana.d553248623199107606.Destination-Travel-Guides) ![Plaza Santa Ana, Panama Casco Viejo](https://images.trvl-media.com/place/553248623199107606/b6ad0470-c1f6-4b60-92c8-74bd8158bfc9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in Santa Ana, Panama City - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Ana Spa [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&amenities=SPA_ON_SITE) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&travelerType=family_friendly) Apart hotel [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&lodging=APART_HOTEL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&amenities=HOT_TUB) Pool [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&amenities=POOL) Ocean view [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&amenities=OCEAN_VIEW) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&lodging=APARTMENT) Condo [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&lodging=CONDO) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&amenities=PETS) ## Check prices for these dates Tonight [Dec 14 - Dec 15](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2025-12-14&endDate=2025-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 15 - Dec 16](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2025-12-15&endDate=2025-12-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Santa Ana hotels ![Luxury Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Duplex | Living area](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/32dc2d2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/762cceb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Private kitchen](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/041fa75e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casco View Apartments [](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) Santa Ana 9.2/10 Wonderful (54) "Great stay, would recommend." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brooke CA $114 CA $125 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Apartment (20)](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/dacdb94e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/7977bbcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Apartment | Living area](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/bc995ff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Apartment | Living area](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/d5acebbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Manzana by Wynwood House [](https://www.expedia.ca/Panama-City-Hotels-La-Manzana-By-Wynwood-House.h100572489.Hotel-Information) Santa Ana 7.2/10 Good (15) "Great hotel. Very close to Casco viejo" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LUCILA CA $105 CA $154 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Panama-City-Hotels-La-Manzana-By-Wynwood-House.h100572489.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/4a38aa01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/83a1ee2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Double Bed](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/132a0077.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/3e5ecf32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hostal La Cigarra [](https://www.expedia.ca/Panama-City-Hotels-Hostal-La-Cigarra.h87396713.Hotel-Information) Santa Ana 7.6/10 Good (55) "Excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) David CA $32 CA $36 total includes taxes & fees Jan 3 - Jan 4, 2026 [](https://www.expedia.ca/Panama-City-Hotels-Hostal-La-Cigarra.h87396713.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/9363bddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/946c31e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room | View from room](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/77400971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/92156b5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel República [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) Santa Ana 6.6/10 (182) "Fantastic customer service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) OLGA [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/a4e5c85a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room, 1 Double Bed | Bathroom](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/b05b8020.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/6917aaca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/f0903154.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ART CASCO The Hotel [](https://www.expedia.ca/Panama-City-Hotels-ART-CASCO-The-Hotel.h89836824.Hotel-Information) Santa Ana 5.8/10 (10) "Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eldris [](https://www.expedia.ca/Panama-City-Hotels-ART-CASCO-The-Hotel.h89836824.Hotel-Information) ![Room, Multiple Bedrooms, Accessible, Smoking | Pool](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/b9369105.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Bedrooms, Accessible, Smoking | Fitness studio](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/w2048h1361x0y0-8b7f1fa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Bedrooms, Accessible, Smoking | Lounge](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/141773b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Bedrooms, Accessible, Smoking | Living room](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/w2048h1361x0y0-35b02ec8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Room-sofa Bed Stay Rooftop Pool & Gym, A [](https://www.expedia.ca/Panama-City-Hotels-Room-In-Guest-Room-Sofa.h112906538.Hotel-Information) Santa Ana 2.0/10 (1) "You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cristian Camilo Betancur CA $202 CA $222 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Panama-City-Hotels-Room-In-Guest-Room-Sofa.h112906538.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/3645c5b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![San Felipe Junior Suite, 1 Double bed or 2 Single Beds](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/4964bad8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/f174b378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive House | Living area](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/ed2f4dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Concordia Boutique Hotel [](https://www.expedia.ca/Panama-City-Hotels-La-Concordia-Boutique-Hotel.h17380132.Hotel-Information) San Felipe, 0.5 km from Santa Ana 9.6/10 Exceptional (194) "Beautiful room Good location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karla CA $344 CA $379 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Panama-City-Hotels-La-Concordia-Boutique-Hotel.h17380132.Hotel-Information) ![47-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/w6390h4261x0y0-9ab7a08c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 King Bed, Jetted Tub | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/09deaa1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/174f9ccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Central Hotel Panama Casco Viejo [](https://www.expedia.ca/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) San Felipe, 0.9 km from Santa Ana 9.0/10 Wonderful (1004) "Excellent hotel , good breakfast, great location, would highly recommend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Glen CA $278 CA $306 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) ![Breakfast and dinner served, international cuisine](https://images.trvl-media.com/lodging/77000000/76550000/76546200/76546151/181eaefd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/77000000/76550000/76546200/76546151/8ea510da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, memory foam beds, minibar, in-room safe](https://images.trvl-media.com/lodging/77000000/76550000/76546200/76546151/0f7b9ebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Studio Suite](https://images.trvl-media.com/lodging/77000000/76550000/76546200/76546151/8e46dffd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amarla Boutique Hotel Casco Viejo [](https://www.expedia.ca/Panama-City-Hotels-Amarla-Panama-Boutique-Hotel.h76546151.Hotel-Information) San Felipe, 0.9 km from Santa Ana 9.6/10 Exceptional (106) "Great little hotel in Casco Viejo. Rooms are small, but comfortable. Reception is a bit odd, but service was nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frederick [](https://www.expedia.ca/Panama-City-Hotels-Amarla-Panama-Boutique-Hotel.h76546151.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/febf3b4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/c8d2e545.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Double Room](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/be626324.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/d1a4e6a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ORHO HOTEL BOUTIQUE PANAMA Airport [](https://www.expedia.ca/Tocumen-Hotels-ORHO-HOTEL-BOUTIQUE-PANAMA-Airport.h119860522.Hotel-Information) 20.5 km from Santa Ana 9.0/10 Wonderful (37) "It was a cool unique antique place that had modern touches. The staff was very friendly and helpful. Will definitely stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clarissa CA $165 CA $182 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Tocumen-Hotels-ORHO-HOTEL-BOUTIQUE-PANAMA-Airport.h119860522.Hotel-Information) ![Suite, 1 Bedroom, Golf View (Terrace)](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/d80494b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/e5856e04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/1e4d9048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/c77947e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City [](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) Juan Diaz, 12.7 km from Santa Ana 9.6/10 Exceptional (638) "As usual the stay was amazing in this hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose CA $319 CA $351 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![4 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/11d7a719.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/08d313d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/22b0bcbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/0babe4e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Panama [](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) Punta Pacifica, 4.3 km from Santa Ana 9.0/10 Wonderful (1007) "Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarran CA $346 CA $380 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/486951c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, City View | City view](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/cc5e4adc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms, City View](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/b2066790.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/7fb69592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sortis Hotel, Spa & Casino, Autograph Collection by Marriott [](https://www.expedia.ca/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) Obarrio, 4.1 km from Santa Ana 8.8/10 Excellent (1003) "Amazing amazing service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) KFIR CA $219 CA $241 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/c91b2bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe | City view](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/607e2a08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/096c0ccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza Panama [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) Campo Alegre, 3.6 km from Santa Ana 9.0/10 Wonderful (4665) "Awesome great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Herbert CA $176 CA $194 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/91000000/90810000/90801900/90801879/c11e781a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/91000000/90810000/90801900/90801879/7b798faa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (King size bed)](https://images.trvl-media.com/lodging/91000000/90810000/90801900/90801879/e08a3084.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90810000/90801900/90801879/a437809a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MARINN PLACE Financial District [](https://www.expedia.ca/Panama-City-Hotels-MARINN-Place-Financial-Distrit.h90801879.Hotel-Information) Campo Alegre, 3.3 km from Santa Ana 9.2/10 Wonderful (299) "Second stay, very nice" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Xiaozhi CA $246 CA $270 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Panama-City-Hotels-MARINN-Place-Financial-Distrit.h90801879.Hotel-Information) ![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/d8a24106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/0e5b4d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, sun loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/e679a1c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Playa Bonita Panama [](https://www.expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) 7.5 km from Santa Ana 8.0/10 Very good (1002) "Our stay was very nice, the service the hotel provides is wonderful, I highly recommend it" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mayra Alexandra Montes CA $274 CA $301 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/17000000/16280000/16271000/16270978/e4528cc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/17000000/16280000/16271000/16270978/cd8eccf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Private kitchen](https://images.trvl-media.com/lodging/17000000/16280000/16271000/16270978/1d6a8ef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, soundproofing, free WiFi](https://images.trvl-media.com/lodging/17000000/16280000/16271000/16270978/9c211996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Caprichosa [](https://www.expedia.ca/Taboga-Hotels-Villa-Caprichosa.h16270978.Hotel-Information) 18.3 km from Santa Ana 9.8/10 Exceptional (42) "We loved the place and the attention given by the staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juan Carlos CA $344 CA $379 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Taboga-Hotels-Villa-Caprichosa.h16270978.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/fae422a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite 1 King Oceant Front](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/4debbd4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/3e3dec8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/edb97b6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel Legend Casco Viejo, Panama City [](https://www.expedia.ca/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information) San Felipe, 1.1 km from Santa Ana 9.8/10 Exceptional (557) "Great hotel and location " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Russell CA $521 CA $573 total includes taxes & fees Jan 13 - Jan 14, 2026 [](https://www.expedia.ca/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information) ![Executive Duplex | Terrace/patio](https://images.trvl-media.com/lodging/91000000/90060000/90050600/90050566/eefb1800.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Elite Suite | Terrace/patio](https://images.trvl-media.com/lodging/91000000/90060000/90050600/90050566/7ffafba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Duplex | Living area](https://images.trvl-media.com/lodging/91000000/90060000/90050600/90050566/61045c82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90060000/90050600/90050566/66c07aa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Oasis Hotel [](https://www.expedia.ca/Panama-City-Hotels-Oasis-Hotel.h90050566.Hotel-Information) San Felipe, 0.6 km from Santa Ana 8.6/10 Excellent (103) "Very friendly staff and good location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edward CA $82 CA $90 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/Panama-City-Hotels-Oasis-Hotel.h90050566.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/60000/53200/53197/86983e15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/53200/53197/0f74aa3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/60000/53200/53197/dc36a369.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/60000/53200/53197/52027201.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InterContinental Miramar Panama by IHG [](https://www.expedia.ca/Panama-City-Hotels-InterContinental-Miramar-Panama.h53197.Hotel-Information) Bella Vista, 2.6 km from Santa Ana 8.6/10 Excellent (533) "Room was excellent… meals that accompanied room were good and the staff was friendly and helpful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hanley Clifton CA $234 CA $258 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Panama-City-Hotels-InterContinental-Miramar-Panama.h53197.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-28&endDate=2025-12-29®ionId=553248623199107606&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Santa Ana Find the best Santa Ana areas and neighborhoods for the activities you enjoy most. - Casco Viejo - Bella Vista - El Cangrejo - San Francisco - Punta Paitilla [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6285189) ![Casco Viejo map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:w%7Csu%40z%7CmdNsAsJNa%40sCsD%60HKJ%7DFO_Ai%40A%3F%5B%5C%3FBmAXC%7D%40aBd%40yBj%40%3FB%7D%40b%40%40Nl%40t%40I%60%40uA%7C%40D%40r%40%7ECNNm%40%60AIaAAVoCbFdAjB%7B%40pEvAKn%40_J%7CB%3FzDt%40%3FHnDZCKl%40f%40bAq%40r%40GrApAFQrAlBp%40O%7EBgEY%5CrCr%40%5EVxAiSFmDpA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=uEe2tFISgoY2i6D1L7Cp-Szzr7E=) ### Casco Viejo Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6285189) ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/d5ab8e549e1cfa831dcb33b7e1b0352d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/919b43d85bf36a400b3c07d30881f725.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/de251296a0096f0bf5fd9914c545600d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/a8f0f1d663e33ab4f81206a124826dcd.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=3000663485) ![Bella Vista map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ksxu%40xrmdNeY_Ea%60Ach%40wd%40eZ%60AmN%60KeE%7EE%7DIvIw%40bC%7BFvJkEf%40cEx%5BaVbHnA%7CGrN%60HxCfGnFlD_AhLfHlHj%40%60EiErGh%40tIfx%40qFbFoH%7Cc%40aI_BsItR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=kybUo6TOAHV5XfFCWEb1fcek5LQ=) ### Bella Vista Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Crown Casino. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. [See properties](https://www.expedia.ca/Hotel-Search?regionId=3000663485) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6285972) ![El Cangrejo map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7Bpzu%40%60xldN%7D%5BcRdDeKmFiDvDaNbCgGxW%7D%40rIrDpFzGvJpGwFlIpFnGg%60%40zR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=TyMwYMNUwH4f3VdmHvCgBWau0RI=) ### El Cangrejo The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6285972) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248623199112076) ![San Francisco map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wr%7Bu%40hdjdNiV%7BDud%40_SiCcEAqJ%7B%40aEkW_Zh%5EeK%7E%40_CWkNbDFxD%7BAgA%7BEqBqDL%7DDwDoKIkCt%40sBsAgAo%40oBvCKhG%7EDhBFh%40i%40%7C%40CxAx%40zCZrEu%40lA%7D%40So%40b%40qChA%7D%40dCAtExD%60DrGvCxArDQMwDvBWl%40y%40rAJo%40w%40z%40_AxCrBtBn%40pEpD%7BBlCmAyAt%40dEb%40Nd%40e%40HaAzBkCnFfDFr%40%7B%40h%40Jr%40pIvFlFdL%7EJlJhM%60SlDPbe%40eBrBlAr%40xAA%60AsAtBaFnBO%60%40p%40bEQtF%60HxAi%40lAIoA%7DEQCXz%40VoATQdAn%40p%40lH%40xBrBh%40xBK%60ArAVh%40%7EAvAd%40jD%7ECXjAYhE%5E%5CdBKnAnA_EzD%7BDp%40kBkAyFy%40qAdAqC%5Ec%40b%40yBYuBXaEtDeFi%40qC%7B%40kHiFgAKgBn%40eAE_ByBuEaDcCk%40kAyA_GuMaDB_DiB_A%7CAsFrB%7D%40jEiGjCeDVQfC%7BBx%40HrB%5DhAsIfEgBbE&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=LnVVpfxBpjhgnoVjOyo-4O6-uto=) ### San Francisco San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50\. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248623199112076) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6285983) ![Punta Paitilla map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7Duwu%40rdjdNiAuFgGy%40gEfEcV_JsDpAyBsCzDaDbBgGlGmO%5CiHdFm%40%60IiHvFiA%7CDtP%60W%60KpFzZq%5ExI&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=TYDp5EcfRW6ARRcsV3BbssS7Oco=) ### Punta Paitilla Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6285983) ## Top Santa Ana Hotel Reviews ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "Just a beautiful hotel for any occasion." [](https://expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg) ### Sheraton Grand Panama 10/10 Excellent "Yes" [](https://expedia.ca/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![The Westin Playa Bonita Panama](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e_y.jpg) ### The Westin Playa Bonita Panama 10/10 Excellent "It was a wonderful experience and we’ll be back! " [](https://expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Decapolis Hotel Panama City](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg) ### Decapolis Hotel Panama City 10/10 Excellent "Modern, clean, killer view of the bay and city lights on Balboa Street, huge continental breakfast, friendly bi-lingual staff This has not been my first stay here, it is my go to stay when I am in the city. Expedia has some great prices " [](https://expedia.ca/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "It was pretty comfortable " [](https://expedia.ca/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "I loved my stay! " [](https://expedia.ca/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "This hotel accommodated my husband and I at the last minute. Due to the prior booking we had to relocate. The staff was friendly and helpful. The location was a bit further from Panama City then we would like. But we were grateful to find somewhere to stay due to it being a 3-day holiday. Would definitely stay there again. Everything you need is in this one location." [](https://expedia.ca/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Always nice to stay and have experience the service of the company excels my expectation " [](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg) ### W Panama 10/10 Excellent "excellent " [](https://expedia.ca/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ## Find out more about Santa Ana ### Top reasons to visit Santa Ana - **Historical Attractions:** Visit significant sites like the Santa Ana Church and Iglesia Santa Ana to experience the rich cultural heritage of the area. - **Charming Walking Tours:** Enjoy guided walking tours led by locals, showcasing the unique charm and highlights of Santa Ana. - **Relaxing Green Spaces:** Spend time at Santa Ana Square, a perfect spot for relaxation and enjoying scenic views. - **Diverse Accommodations:** Choose from a wide range of lodging options, from budget to luxury, catering to all types of travelers. - **Proximity to Attractions:** Easily access nearby popular attractions like Casco Viejo and Parque Natural Metropolitano for day trips. ### Find great hotels near Santa Ana Santa Ana boasts a diverse selection of accommodations, catering to every traveler's needs, from budget-friendly lodgings to luxurious 5-star hotels. Whether you're seeking a charming lodge or a modern hotel, you'll find options that provide essential services for city exploration, business trips, or a pet-friendly getaway. Discover the best hotels in Santa Ana and enjoy a memorable stay in the heart of Panama City. - **[Central Hotel Panama Casco Viejo:](https://www.expedia.ca/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information)** Nestled in the vibrant Casco Viejo district, Central Hotel Panama offers a romantic and luxurious environment perfect for couples and business travellers alike. This 4-star gem is renowned for its exceptional spa services, featuring a full-service spa, steam room, and facial treatments to soothe your senses. With a strong focus on romance, guests can indulge in packages that include champagne service and 24-hour room service. For business needs, the hotel provides accessible meeting rooms and conference spaces, ensuring a seamless experience for professionals. - **[American Trade Hotel:](https://www.expedia.ca/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information)** Located in the heart of Panama City, the American Trade Hotel blends adventure, family-friendly amenities, and romantic touches into a unique lodging experience. This 4.5-star hotel boasts proximity to outdoor activities such as biking, hiking, and even Segway rentals, making it ideal for adventurous families. Guests can enjoy garden views from the restaurant while savouring limited-hour room service and champagne service. The outdoor pool area, complete with sun loungers and in-room massage options, provides a relaxing retreat for couples seeking a romantic getaway. - **Sofitel Legend Casco Viejo, Panama City:** This 5-star luxury hotel embodies elegance and sophistication in the historic Casco Viejo area. With a strong emphasis on business and leisure, it offers accessible business centres and comprehensive facilities for corporate travellers. Guests can unwind at the spa, which features treatment rooms and a swim-up bar, perfect for relaxation after a busy day. The hotel's exquisite design and top-notch services make it a premier choice for discerning travellers looking for an unforgettable experience in Panama City. ### Where to stay near Santa Ana Santa Ana, a vibrant neighbourhood in Panama City, offers a delightful mix of family-friendly activities and historical charm. Explore the bustling streets filled with friendly locals, and immerse yourself in the unique atmosphere of Panama's capital. Nearby, attractions like the historic Casco Viejo and the scenic Parque Natural Metropolitano provide perfect day trips. Whether you’re seeking a city-themed adventure or a relaxing family holiday, Santa Ana is an ideal base for discovering the rich culture of Panamá Province. - **[Panama City:](https://www.expedia.ca/Panama-City-Hotels.d2897.Travel-Guide-Hotels)** As the vibrant capital of Panama, Panama City is a bustling metropolis rich in culture and history. Nestled in the heart of the country, it offers a diverse travel experience, appealing to families, business travellers, and city explorers alike. The city showcases a stunning mix of modern skyscrapers and colonial architecture. Visitors can enjoy shopping at prominent centres and malls, while the nearby beaches, parks, and lively streets invite exploration and relaxation. With visitor numbers peaking in January, July, and September, it's an ideal destination year-round. - **[Casco Viejo:](https://www.expedia.ca/Casco-Viejo-Panama-City-Hotels.0-n6285189-0.Travel-Guide-Filter-Hotels)** Located a mere 644m from Santa Ana, Casco Viejo is a UNESCO World Heritage site known for its charming cobblestone streets and historic buildings. This neighbourhood is a hub of activity, making it perfect for families and city adventurers. With vibrant shopping centres, resorts, and delightful dining options, Casco Viejo is a picturesque setting for exploration. Enjoy the nearby beaches and parks, as well as the unique street life that adds to its cultural richness. Peak visitor months include January and March to April, offering a lively atmosphere. - **[San Felipe:](https://www.expedia.ca/San-Felipe-Panama-City-Hotels.0-n829297728598073344-0.Travel-Guide-Filter-Hotels)** Also situated 644m away from Santa Ana, San Felipe is a captivating neighbourhood known for its historic significance and charming streets. This area attracts families, business travellers, and city explorers, offering a mix of shopping malls and local boutiques. Visitors can explore the nearby beaches, historic places, and monuments that tell the story of Panama's past. With peak tourist arrivals from December to February, San Felipe provides a vibrant yet tranquil atmosphere for a memorable vacation. ### Things to do near Santa Ana Santa Ana, a vibrant neighbourhood in Panama City, is perfect for family and business vacations. Visitors can enjoy a variety of activities, including exploring shopping malls and unique shopping areas. Don't miss the chance to embark on a walking tour of Santa Ana, guided by knowledgeable locals, to discover touristy spots and enjoy pleasant strolls through this charming district. **Shopping** In Santa Ana, you can visit Avenida Central, located 483m away, offering a vibrant mix of family-friendly shops and entertainment. Albrook Shopping Mall, just 1.6km away, is perfect for family outings. If you're up for a drive, check out Uruguay Street, located 3.2km away, for more local shopping experiences. **Recreation** Experience the vibrant atmosphere at [Maracana Stadium](https://www.expedia.ca/Maracana-Stadium-Hotels.0-l553248621562725885-0.Travel-Guide-Filter-Hotels), located 1.3km from Santa Ana, perfect for sports enthusiasts. For an exhilarating outing, head to Estadio Nacional Rod Carew, 9.7km away, or Estadio Rommel Fernandez, 11.3km away, both offering thrilling sports events and energetic vibes. **Adventure** Embark on the Honeycreeper Ridge Trail, located 211.3km from Santa Ana, for a scenic hike surrounded by vibrant nature. For a thrilling experience, visit Gatun Eco Adventures, situated 48.3km away, where you can soar through the treetops on an exhilarating zipline ropes course. **Nightlife** Experience the vibrant nightlife in Santa Ana by visiting Crown Casino, just 3.2km away, for thrilling games and romance. For a cultural evening, enjoy a show at the National Theater (0.9.7km away) or Anita Villalaz Theater (1.3km away), both offering family-friendly entertainment and a romantic atmosphere. ### Booking tips and Expedia advantages for Santa Ana When visiting Santa Ana, Panama, consider exploring free attractions like Albrook Shopping Mall and Cinta Costera. To save on accommodation, travel during the off-peak months from September to November, when prices are lower compared to peak times like March and December to January. Tuesdays are typically the cheapest days to stay, while Saturdays are the most expensive. Use Expedia to compare prices and book packages that combine flights and hotels for added savings. Don't forget to filter for eco-certified hotels to find sustainable options that fit your budget. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay around Santa Ana are September to November, where the prices are slightly lower. This is in comparison to March and December to January, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay around Santa Ana is Tuesday. The most expensive day to stay around Santa Ana is Saturday. - **Find cheap hotels on Expedia:** Expedia’s search tool enables you to choose your budget, preferred location, and additional criteria. You can easily sort your results to display prices from lowest to highest, allowing you to find the most affordable hotels right away. Additionally, you can refine your choices by hotel type—select the "Eco-certified" filter to discover sustainable and environmentally-friendly accommodations available for booking. - **Consider bundling your trip:** You can save money by combining your Santa Ana hotel reservation with your flights and activities when you book an Expedia package. ### Find the best attractions near Santa Ana Santa Ana, located in Panama City, is perfect for family and business vacations, offering a rich cultural experience. Visitors can explore historical sites such as the Santa Ana Church and Iglesia Santa Ana, relax at Santa Ana Square, and enjoy scenic views near the canyon. The area's attractions cater to those seeking a blend of history and city life, making it an ideal destination for tourists looking to immerse themselves in local culture. - **[Metropolitan Cathedral of Panama:](https://www.expedia.ca/Metropolitan-Cathedral-Of-Panama-Hotels.0-l6078477-0.Travel-Guide-Filter-Hotels)** Located 805m from Santa Ana, this stunning cathedral showcases remarkable colonial architecture and intricate artwork. It serves as a cultural hub, offering a glimpse into Panama's rich history and religious heritage. - **Ancon Hill:** Just 966m from Santa Ana, Ancon Hill provides breathtaking panoramic views of Panama City and the Panama Canal. This outdoor oasis is perfect for hiking and enjoying nature while immersing yourself in the area's scenic beauty. - **Interoceanic Canal Museum:** Situated 805m away, this museum is dedicated to the history of the Panama Canal. It features fascinating exhibits that highlight the canal's significance, making it a must-visit for culture enthusiasts. ### Best time to go to Santa Ana Visitor numbers around Santa Ana is generally unchanged in popularity throughout the year. The best time to visit Santa Ana can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santa Ana falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around Santa Ana falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain. | **![calendar icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly cloudy icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation rate icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------- | --------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------ | ------------------------------------------------------------------------------------------------------------------ | | January | 78.8°F (26.0°C) | No Rain (Dry) | Mostly Sunny | Slightly High | Slightly High | | February | 79.2°F (26.2°C) | No Rain (Dry) | Mostly Sunny | Slightly High | Average | | March | 79.7°F (26.5°C) | No Rain (Dry) | Mostly Sunny | Average | Slightly High | | April | 80.4°F (26.9°C) | Light Rain | Mostly Sunny | Average | Average | | May | 80.2°F (26.8°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Average | | June | 79.9°F (26.6°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Average | | July | 79.3°F (26.3°C) | Frequent Rain | Mostly Cloudy | Average | Average | | August | 79.2°F (26.2°C) | Frequent Rain | Mostly Cloudy | Average | Average | | September | 79.3°F (26.3°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Slightly Low | | October | 78.6°F (25.9°C) | Frequent Rain | Mostly Cloudy | Average | Slightly Low | | November | 78.3°F (25.7°C) | Frequent Rain | Mostly Cloudy | Average | Slightly Low | | December | 78.6°F (25.9°C) | Light Rain | Mostly Cloudy | Slightly High | Slightly High | ### The nearest major airports for your trip to Santa Ana When visiting Santa Ana, you have convenient access to two major airports. Panama City ([PTY](https://www.expedia.ca/Tocumen-Intl-Airport-Hotels.0-aPTY-0.Travel-Guide-Filter-Hotels)\-Tocumen Intl.) is located 20.9km away, with notable hotels like [The Santa Maria](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information), A Luxury Collection Hotel & Golf Resort, 8.0km from the airport, and [JW Marriott Panama](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information), 16.1km away. Alternatively, Panama City ([PAC](https://www.expedia.ca/Marcos-A-Gelabert-Intl-Airport-Hotels.0-aPAC-0.Travel-Guide-Filter-Hotels)\-Marcos A. Gelabert Intl.) is only 3.2km from Santa Ana, featuring excellent accommodations such as [Waldorf Astoria Panama](https://www.expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information), just 3.2km away, and [Hilton Panama](https://www.expedia.ca/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information), 4.8km away. Transportation services from these hotels to the airports typically include on-request shuttle services, offering ease and comfort for your travel needs. ## Frequently asked questions ### What are the best budget hotels in Santa Ana? > For those seeking a luxurious experience without breaking the bank, [Hotel República](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) presents a charming option with its rooftop terrace providing partial ocean views, superb for relaxing after a day of adventures. This hotel also features free WiFi and air conditioning, ensuring comfort during your stay. Families can take advantage of the area shuttle service to explore Panama City's attractions conveniently. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa Ana hotel booking with Expedia? ### How much is the nightly rate at a Santa Ana hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - [5 Star Hotels in Casco Viejo ](https://www.expedia.ca/5Star-Casco-Viejo-Panama-City-Hotels.s50-n6285189-0.Travel-Guide-Filter-Hotels) - [Hotels near Albrook Shopping Mall ](https://www.expedia.ca/Albrook-Shopping-Mall-Hotels.0-l6159851-0.Travel-Guide-Filter-Hotels) - [Amador Hotels ](https://www.expedia.ca/Amador-Panama-City-Hotels.0-n553248635933392377-0.Travel-Guide-Filter-Hotels) - [Hotels near Avenida Balboa ](https://www.expedia.ca/Avenida-Balboa-Hotels.0-l553248623453290531-0.Travel-Guide-Filter-Hotels) - [Balboa Hotels ](https://www.expedia.ca/Balboa-Panama-City-Hotels.0-n6323179-0.Travel-Guide-Filter-Hotels) - 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[Visit Panamá Province ](https://www.expedia.ca/Panama-Province.dx6246281) - [Car rentals near Albrook Shopping Mall ](https://www.expedia.ca/Car-Rentals-In-Albrook-Shopping-Mall.d6159851.Car-Rental-Guide) - [Car rentals near Balboa ](https://www.expedia.ca/Car-Rentals-In-Balboa.d6323179.Car-Rental-Guide) - [Panamá Province Vacation Rentals ](https://www.expedia.ca/Destinations-In-Panama-Province.d6246281.Vacation-Rental-Destinations)