Title: 10 Best Hotels in Santa Ana, Panama City for 2026 | Expedia.ca [Vacation Rentals in Panama City](https://expedia.ca/Panama-City-Vacation-Rentals.d2897.Travel-Guide-VacationRentals)[Flights to Panama City](https://expedia.ca/Cheap-Flights-To-Panama-City.d2897.Travel-Guide-Flights)[Things to do in Panama City](https://expedia.ca/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities)[Santa Ana Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Ana.d553248623199107606.Car-Rental-Guide)[Santa Ana Vacations](https://expedia.ca/Santa-Ana.d553248623199107606.Destination-Travel-Guides) ![Plaza Santa Ana, Panama Casco Viejo](https://images.trvl-media.com/place/553248623199107606/b6ad0470-c1f6-4b60-92c8-74bd8158bfc9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248623199107606/b6ad0470-c1f6-4b60-92c8-74bd8158bfc9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 29 - Jan 30](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2026-01-29&endDate=2026-01-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 30 - Jan 31](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2026-01-30&endDate=2026-01-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Santa Ana hotels ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/4a38aa01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Double Bed](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/c38aaf6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/3e5ecf32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/w975h728x4y7-51ba2508.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hostal La Cigarra [](https://www.expedia.ca/Panama-City-Hotels-Hostal-La-Cigarra.h87396713.Hotel-Information) Santa Ana 7.6/10 Good (59 reviews) "Excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) David [](https://www.expedia.ca/Panama-City-Hotels-Hostal-La-Cigarra.h87396713.Hotel-Information) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/w846h1318x0y4-5df5c378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/762cceb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment | Living area](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/03e26607.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ba5a7e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casco View Apartments [](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) Santa Ana 9.0/10 Wonderful (66 reviews) "We live this property and stay here whenever we are in town." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) chris CA $112 CA $123 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Double Room | View from room](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/77400971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/ce5bf1ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/92156b5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/946c31e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel República [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) Santa Ana 6.6/10 (182 reviews) "Super outdated. Looks dangerous in the area" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nina Kristine [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) ![Apartment (20)](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/dacdb94e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/6c701342.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Apartment | Dining room](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/ef205966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (05) | Living area](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/679f386c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Manzana by Wynwood House [](https://www.expedia.ca/Panama-City-Hotels-La-Manzana-By-Wynwood-House.h100572489.Hotel-Information) Santa Ana 7.2/10 Good (15 reviews) "Great hotel. Very close to Casco viejo" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LUCILA CA $93 CA $140 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Panama-City-Hotels-La-Manzana-By-Wynwood-House.h100572489.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/bf18b63d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room, 2 Double Beds, Ensuite, Ground Floor](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/de48ce4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/1c70a5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/98e777ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Panama House Bed & Breakfast [](https://www.expedia.ca/Panama-City-Hotels-Panama-House-Bed-Breakfast.h11845091.Hotel-Information) Bella Vista, 4.6 km from Santa Ana 9.0/10 Wonderful (189 reviews) "It was a great stay in a great neighborhood with many food and beverage options, fantastic hosts and an interesting mix of people " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Brad CA $56 CA $62 total includes taxes & fees Feb 4 - Feb 5 [](https://www.expedia.ca/Panama-City-Hotels-Panama-House-Bed-Breakfast.h11845091.Hotel-Information) ![Double Room](https://images.trvl-media.com/lodging/3000000/2230000/2227800/2227716/0fabff69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lake](https://images.trvl-media.com/lodging/3000000/2230000/2227800/2227716/44f4155c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Airport shuttle](https://images.trvl-media.com/lodging/3000000/2230000/2227800/2227716/762ab2a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, international cuisine](https://images.trvl-media.com/lodging/3000000/2230000/2227800/2227716/2132d974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Montreal [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Montreal.h2227716.Hotel-Information) Bella Vista, 2.7 km from Santa Ana 6.0/10 (404 reviews) "The hotel was as I expected. Nothing fancy but clean, comfortable, with easy access from the city. There was parking always available. The restaurant, bar, and the pool were open. The people who worked there had the best predisposition to help and make our time in the hotel great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria Eugenia Fourcade CA $35 CA $39 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Montreal.h2227716.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/a4c743af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/deeb0964.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/49b75ad6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/5668186f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Panama Centro Via Argentina [](https://www.expedia.ca/Panama-City-Hotels-Ramada-Panama-Centro-Via-Argentina.h10412883.Hotel-Information) El Cangrejo, 3.8 km from Santa Ana 7.4/10 Good (279 reviews) "Good room - clean and quiet, Hotel location is on a commercial street with many restaurants and bars nearby and within walking distance to a metro station. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) P CA $98 CA $108 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Panama-City-Hotels-Ramada-Panama-Centro-Via-Argentina.h10412883.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/890400/890364/4bd8a8dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/900000/890400/890364/e89e5bba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/890400/890364/54ff0574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/900000/890400/890364/b96a76c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza Panama by IHG [](https://www.expedia.ca/Panama-City-Hotels-Crowne-Plaza-Panama.h890364.Hotel-Information) Bella Vista, 3.2 km from Santa Ana 8.0/10 Very good (216 reviews) "Staff were amazing . Great breakfast and convenient area close to the train station " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darius CA $119 CA $131 total includes taxes & fees Feb 27 - Feb 28 [](https://www.expedia.ca/Panama-City-Hotels-Crowne-Plaza-Panama.h890364.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4620000/4616300/4616247/505c9cd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Single Room, 1 King Bed](https://images.trvl-media.com/lodging/5000000/4620000/4616300/4616247/d3e08235.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/5000000/4620000/4616300/4616247/54d18d6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/5000000/4620000/4616300/4616247/0f21996a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Toscana Inn [](https://www.expedia.ca/Panama-City-Hotels-Toscana-Inn.h4616247.Hotel-Information) El Cangrejo, 3.7 km from Santa Ana 9.0/10 Wonderful (731 reviews) "Very good spot for the price. Very close to everything. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kartar CA $103 CA $114 total includes taxes & fees Jan 31 - Feb 1 [](https://www.expedia.ca/Panama-City-Hotels-Toscana-Inn.h4616247.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/5000000/4630000/4624400/4624380/11538b34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Studio, 1 King Bed with Sofa bed, Balcony | Balcony](https://images.trvl-media.com/lodging/5000000/4630000/4624400/4624380/6c8d5508.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![King Room - Disability Acces](https://images.trvl-media.com/lodging/5000000/4630000/4624400/4624380/d4f6de92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/5000000/4630000/4624400/4624380/e2cd90e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel y Casino Central Park Panama [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Y-Casino-Central-Park-Panama.h4624380.Hotel-Information) Bethania, 5.6 km from Santa Ana 7.6/10 Good (433 reviews) "Great service, clean, great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) EDGAR CA $88 CA $97 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Y-Casino-Central-Park-Panama.h4624380.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/91000000/90810000/90801900/90801879/b662a355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, memory foam beds, in-room safe](https://images.trvl-media.com/lodging/91000000/90810000/90801900/90801879/08cafa9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/91000000/90810000/90801900/90801879/e8703472.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/91000000/90810000/90801900/90801879/9c609bea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MARINN PLACE Financial District [](https://www.expedia.ca/Panama-City-Hotels-MARINN-Place-Financial-Distrit.h90801879.Hotel-Information) Campo Alegre, 3.3 km from Santa Ana 9.2/10 Wonderful (305 reviews) "Second stay, very nice" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Xiaozhi CA $113 CA $124 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Panama-City-Hotels-MARINN-Place-Financial-Distrit.h90801879.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/6000000/5220000/5219200/5219140/4f20b421.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (PAB 16.5 per person)](https://images.trvl-media.com/lodging/6000000/5220000/5219200/5219140/16c5b512.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5220000/5219200/5219140/03492eb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5220000/5219200/5219140/9961e11f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Panama City Downtown, Panama [](https://www.expedia.ca/Panama-City-Hotels-Hilton-Garden-Inn-Panama-City-Downtown.h5219140.Hotel-Information) El Cangrejo, 3.4 km from Santa Ana 8.6/10 Excellent (1,000 reviews) "Staff very friendly. Good breakfast. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Liam CA $128 CA $140 total includes taxes & fees Feb 6 - Feb 7 [](https://www.expedia.ca/Panama-City-Hotels-Hilton-Garden-Inn-Panama-City-Downtown.h5219140.Hotel-Information) ![Classic Double Room, 1 Double Bed, Non Smoking](https://images.trvl-media.com/lodging/30000000/29420000/29417900/29417859/f2c20ae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/30000000/29420000/29417900/29417859/80e5197c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/30000000/29420000/29417900/29417859/6c875dd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/30000000/29420000/29417900/29417859/3012da90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Acapulco [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Acapulco.h29417859.Hotel-Information) Calidonia, 1.3 km from Santa Ana 7.8/10 Good (131 reviews) "Place is convenient for local shopping local restaurants and access to train. The room is basic but not in a bad way it not luxury but it was clean and staff were all friendly I was there for a short stay and had no complaints. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James CA $38 CA $42 total includes taxes & fees Feb 4 - Feb 5 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Acapulco.h29417859.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/c1c9d6fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Geo Orga by Mariery Young](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/4fafb76c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/fab1c02b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Fusion cuisine ](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/255ee499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tantalo Hotel [](https://www.expedia.ca/Panama-City-Hotels-Tantalo-Hotel-Kitchen-Roofbar.h4880470.Hotel-Information) San Felipe, 0.7 km from Santa Ana 8.8/10 Excellent (280 reviews) "Staff was amazing!! Room was great as well!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John [](https://www.expedia.ca/Panama-City-Hotels-Tantalo-Hotel-Kitchen-Roofbar.h4880470.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/45000000/44130000/44123200/44123136/850ba6b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/45000000/44130000/44123200/44123136/3f92d8f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/45000000/44130000/44123200/44123136/e545228a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, laptop workspace, soundproofing, free WiFi](https://images.trvl-media.com/lodging/45000000/44130000/44123200/44123136/4f8ea47c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gran Evenia Panama [](https://www.expedia.ca/Panama-City-Hotels-Gran-Evenia-Panama.h44123136.Hotel-Information) El Cangrejo, 3.8 km from Santa Ana 9.2/10 Wonderful (211 reviews) "Great location and great staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shaunqualia Lakice CA $203 CA $226 total includes taxes & fees Feb 11 - Feb 12 [](https://www.expedia.ca/Panama-City-Hotels-Gran-Evenia-Panama.h44123136.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8120000/8115400/8115364/fd309502.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Local cuisine](https://images.trvl-media.com/lodging/9000000/8120000/8115400/8115364/b0782bdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/9000000/8120000/8115400/8115364/1b511a49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/9000000/8120000/8115400/8115364/e5b81d9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Vía España [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Via-Espana.h8115364.Hotel-Information) Calidonia, 2.4 km from Santa Ana 6.2/10 (174 reviews) "Don’t stay there it’s the " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andreas [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Via-Espana.h8115364.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/1012405e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 2 Double Beds | Living area](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/871ef81e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Apartment | View from room](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/1b369fc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/03c049bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Torres de Alba Hotel & Suites [](https://www.expedia.ca/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) El Cangrejo, 3.4 km from Santa Ana 8.8/10 Excellent (506 reviews) "Excellent place, friendly staff, great breakfast and many shops close by. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Raymond CA $126 CA $138 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/8000000/7060000/7057300/7057295/f45b1ad3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/8000000/7060000/7057300/7057295/f8b1821f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Accessible, City View](https://images.trvl-media.com/lodging/8000000/7060000/7057300/7057295/d2c9e4be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/8000000/7060000/7057300/7057295/3b29d54b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton by Hilton Panama [](https://www.expedia.ca/Panama-City-Hotels-Hampton-By-Hilton-Panama.h7057295.Hotel-Information) El Cangrejo, 3.8 km from Santa Ana 7.8/10 Good (1,009 reviews) "Room clean and great customer service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edilka CA $126 CA $139 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/Panama-City-Hotels-Hampton-By-Hilton-Panama.h7057295.Hotel-Information) ![Ecotours](https://images.trvl-media.com/lodging/10000000/9560000/9560000/9559935/e3c29c9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/9560000/9560000/9559935/d83eff34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ecotours](https://images.trvl-media.com/lodging/10000000/9560000/9560000/9559935/23e2a20b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/10000000/9560000/9560000/9559935/5fd1457c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Pension Corona [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Pension-Corona.h9559935.Hotel-Information) Calidonia, 1.8 km from Santa Ana 7.8/10 Good (114 reviews) "Great spot for the price " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) frank CA $27 CA $29 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Pension-Corona.h9559935.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/6785cd9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/b2fe58e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/cb8e7c14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/532b8393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Panama Canal by IHG [](https://www.expedia.ca/Panama-City-Hotels-Holiday-Inn-Panama-Canal.h2096355.Hotel-Information) 6 km from Santa Ana 8.6/10 Excellent (450 reviews) "The staff was so cordial and nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sonny CA $139 CA $153 total includes taxes & fees Feb 27 - Feb 28 [](https://www.expedia.ca/Panama-City-Hotels-Holiday-Inn-Panama-Canal.h2096355.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-12&endDate=2026-02-13®ionId=553248623199107606&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Santa Ana Find the best Santa Ana areas and neighborhoods for the activities you enjoy most. - Casco Viejo - Bella Vista - El Cangrejo - San Felipe - San Francisco [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6285189) ![Casco Viejo map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:w%7Csu%40z%7CmdNsAsJNa%40sCsD%60HKJ%7DFO_Ai%40A%3F%5B%5C%3FBmAXC%7D%40aBd%40yBj%40%3FB%7D%40b%40%40Nl%40t%40I%60%40uA%7C%40D%40r%40%7ECNNm%40%60AIaAAVoCbFdAjB%7B%40pEvAKn%40_J%7CB%3FzDt%40%3FHnDZCKl%40f%40bAq%40r%40GrApAFQrAlBp%40O%7EBgEY%5CrCr%40%5EVxAiSFmDpA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=uEe2tFISgoY2i6D1L7Cp-Szzr7E=) ### Casco Viejo Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or Palacio de las Garzas while you're exploring the area. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6285189) ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/d5ab8e549e1cfa831dcb33b7e1b0352d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/919b43d85bf36a400b3c07d30881f725.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/de251296a0096f0bf5fd9914c545600d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/a8f0f1d663e33ab4f81206a124826dcd.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=3000663485) ![Bella Vista map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ksxu%40xrmdNeY_Ea%60Ach%40wd%40eZ%60AmN%60KeE%7EE%7DIvIw%40bC%7BFvJkEf%40cEx%5BaVbHnA%7CGrN%60HxCfGnFlD_AhLfHlHj%40%60EiErGh%40tIfx%40qFbFoH%7Cc%40aI_BsItR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=kybUo6TOAHV5XfFCWEb1fcek5LQ=) ### Bella Vista Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Crown Casino. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. [See properties](https://www.expedia.ca/Hotel-Search?regionId=3000663485) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6285972) ![El Cangrejo map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7Bpzu%40%60xldN%7D%5BcRdDeKmFiDvDaNbCgGxW%7D%40rIrDpFzGvJpGwFlIpFnGg%60%40zR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=TyMwYMNUwH4f3VdmHvCgBWau0RI=) ### El Cangrejo The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6285972) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=829297728598073344) ![San Felipe map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:w%7Csu%40z%7CmdNsAsJNa%40sCsD%60HKJ%7DFO_Ai%40A%3F%5B%5C%3FBmAXC%7D%40aBd%40yBj%40%3FB%7D%40b%40%40Nl%40t%40I%60%40uA%7C%40D%40r%40%7ECNNm%40%60AIaAAVoCbFdAjB%7B%40pEvAKn%40_J%7CB%3FzDt%40%3FHnDZCKl%40f%40bAq%40r%40GrApAFQrAlBp%40O%7EBgEY%5CrCr%40%5EVxAiSFmDpA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=uEe2tFISgoY2i6D1L7Cp-Szzr7E=) ### San Felipe If you're spending some time in San Felipe, Interoceanic Canal Museum and Palacio de las Garzas are top sights worth seeing. [See properties](https://www.expedia.ca/Hotel-Search?regionId=829297728598073344) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248623199112076) ![San Francisco map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wr%7Bu%40hdjdNiV%7BDud%40_SiCcEAqJ%7B%40aEkW_Zh%5EeK%7E%40_CWkNbDFxD%7BAgA%7BEqBqDL%7DDwDoKIkCt%40sBsAgAo%40oBvCKhG%7EDhBFh%40i%40%7C%40CxAx%40zCZrEu%40lA%7D%40So%40b%40qChA%7D%40dCAtExD%60DrGvCxArDQMwDvBWl%40y%40rAJo%40w%40z%40_AxCrBtBn%40pEpD%7BBlCmAyAt%40dEb%40Nd%40e%40HaAzBkCnFfDFr%40%7B%40h%40Jr%40pIvFlFdL%7EJlJhM%60SlDPbe%40eBrBlAr%40xAA%60AsAtBaFnBO%60%40p%40bEQtF%60HxAi%40lAIoA%7DEQCXz%40VoATQdAn%40p%40lH%40xBrBh%40xBK%60ArAVh%40%7EAvAd%40jD%7ECXjAYhE%5E%5CdBKnAnA_EzD%7BDp%40kBkAyFy%40qAdAqC%5Ec%40b%40yBYuBXaEtDeFi%40qC%7B%40kHiFgAKgBn%40eAE_ByBuEaDcCk%40kAyA_GuMaDB_DiB_A%7CAsFrB%7D%40jEiGjCeDVQfC%7BBx%40HrB%5DhAsIfEgBbE&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=LnVVpfxBpjhgnoVjOyo-4O6-uto=) ### San Francisco San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50\. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248623199112076) ## Top Santa Ana Hotel Reviews ![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "staff was excellent" [](https://expedia.ca/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "Room was clean, beds were very comfortable, staff was excellent" [](https://expedia.ca/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Great" [](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Friendly and helpful" [](https://expedia.ca/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg) ### Waymore Hotel Spa & Casino 10/10 Excellent "Nice stay. Casino was fun with big TVs to watch games, food was decent with nice accommodations. I would stay again. " [](https://expedia.ca/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg) ### W Panama 10/10 Excellent "Second time staying and it was flawless." [](https://expedia.ca/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "Very good" [](https://expedia.ca/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![The Westin Playa Bonita Panama](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e_y.jpg) ### The Westin Playa Bonita Panama 10/10 Excellent "Everything was phenomenal - the resort, the staff, the food, the drinks and the view. Thx for the Panamanian hospitality! " [](https://expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Novotel Panama City](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/aad97f9d_y.jpg) ### Novotel Panama City 10/10 Excellent "Clean room nice curtains kind staff one thing that could improve is the breakfast needs more choices " [](https://expedia.ca/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) ## Find out more about Santa Ana ### Top reasons to visit Santa Ana - **Historical Attractions:** Visit significant sites like the Santa Ana Church and Iglesia Santa Ana to experience the rich cultural heritage of the area. - **Charming Walking Tours:** Enjoy guided walking tours led by locals, showcasing the unique charm and highlights of Santa Ana. - **Relaxing Green Spaces:** Spend time at Santa Ana Square, a perfect spot for relaxation and enjoying scenic views. - **Diverse Accommodations:** Choose from a wide range of lodging options, from budget to luxury, catering to all types of travelers. - **Proximity to Attractions:** Easily access nearby popular attractions like Casco Viejo and Parque Natural Metropolitano for day trips. ### Find great hotels near Santa Ana Santa Ana boasts a diverse selection of accommodations, catering to every traveler's needs, from budget-friendly lodgings to luxurious 5-star hotels. Whether you're seeking a charming lodge or a modern hotel, you'll find options that provide essential services for city exploration, business trips, or a pet-friendly getaway. Discover the best hotels in Santa Ana and enjoy a memorable stay in the heart of Panama City. - **[Central Hotel Panama Casco Viejo:](https://www.expedia.ca/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information)** Nestled in the vibrant Casco Viejo district, Central Hotel Panama offers a romantic and luxurious environment perfect for couples and business travellers alike. This 4-star gem is renowned for its exceptional spa services, featuring a full-service spa, steam room, and facial treatments to soothe your senses. With a strong focus on romance, guests can indulge in packages that include champagne service and 24-hour room service. For business needs, the hotel provides accessible meeting rooms and conference spaces, ensuring a seamless experience for professionals. - **[American Trade Hotel:](https://www.expedia.ca/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information)** Located in the heart of Panama City, the American Trade Hotel blends adventure, family-friendly amenities, and romantic touches into a unique lodging experience. This 4.5-star hotel boasts proximity to outdoor activities such as biking, hiking, and even Segway rentals, making it ideal for adventurous families. Guests can enjoy garden views from the restaurant while savouring limited-hour room service and champagne service. The outdoor pool area, complete with sun loungers and in-room massage options, provides a relaxing retreat for couples seeking a romantic getaway. - **Sofitel Legend Casco Viejo, Panama City:** This 5-star luxury hotel embodies elegance and sophistication in the historic Casco Viejo area. With a strong emphasis on business and leisure, it offers accessible business centres and comprehensive facilities for corporate travellers. Guests can unwind at the spa, which features treatment rooms and a swim-up bar, perfect for relaxation after a busy day. The hotel's exquisite design and top-notch services make it a premier choice for discerning travellers looking for an unforgettable experience in Panama City. ### Where to stay near Santa Ana Santa Ana, a vibrant neighbourhood in Panama City, offers a delightful mix of family-friendly activities and historical charm. Explore the bustling streets filled with friendly locals, and immerse yourself in the unique atmosphere of Panama's capital. Nearby, attractions like the historic Casco Viejo and the scenic Parque Natural Metropolitano provide perfect day trips. Whether you’re seeking a city-themed adventure or a relaxing family holiday, Santa Ana is an ideal base for discovering the rich culture of Panamá Province. - **[Panama City:](https://www.expedia.ca/Panama-City-Hotels.d2897.Travel-Guide-Hotels)** As the vibrant capital of Panama, Panama City is a bustling metropolis rich in culture and history. Nestled in the heart of the country, it offers a diverse travel experience, appealing to families, business travellers, and city explorers alike. The city showcases a stunning mix of modern skyscrapers and colonial architecture. Visitors can enjoy shopping at prominent centres and malls, while the nearby beaches, parks, and lively streets invite exploration and relaxation. With visitor numbers peaking in January, July, and September, it's an ideal destination year-round. - **[Casco Viejo:](https://www.expedia.ca/Casco-Viejo-Panama-City-Hotels.0-n6285189-0.Travel-Guide-Filter-Hotels)** Located a mere 644m from Santa Ana, Casco Viejo is a UNESCO World Heritage site known for its charming cobblestone streets and historic buildings. This neighbourhood is a hub of activity, making it perfect for families and city adventurers. With vibrant shopping centres, resorts, and delightful dining options, Casco Viejo is a picturesque setting for exploration. Enjoy the nearby beaches and parks, as well as the unique street life that adds to its cultural richness. Peak visitor months include January and March to April, offering a lively atmosphere. - **[San Felipe:](https://www.expedia.ca/San-Felipe-Panama-City-Hotels.0-n829297728598073344-0.Travel-Guide-Filter-Hotels)** Also situated 644m away from Santa Ana, San Felipe is a captivating neighbourhood known for its historic significance and charming streets. This area attracts families, business travellers, and city explorers, offering a mix of shopping malls and local boutiques. Visitors can explore the nearby beaches, historic places, and monuments that tell the story of Panama's past. With peak tourist arrivals from December to February, San Felipe provides a vibrant yet tranquil atmosphere for a memorable vacation. ### Things to do near Santa Ana Santa Ana, a vibrant neighbourhood in Panama City, is perfect for family and business vacations. Visitors can enjoy a variety of activities, including exploring shopping malls and unique shopping areas. Don't miss the chance to embark on a walking tour of Santa Ana, guided by knowledgeable locals, to discover touristy spots and enjoy pleasant strolls through this charming district. **Shopping** In Santa Ana, you can visit Avenida Central, located 483m away, offering a vibrant mix of family-friendly shops and entertainment. Albrook Shopping Mall, just 1.6km away, is perfect for family outings. If you're up for a drive, check out Uruguay Street, located 3.2km away, for more local shopping experiences. **Recreation** Experience the vibrant atmosphere at [Maracana Stadium](https://www.expedia.ca/Maracana-Stadium-Hotels.0-l553248621562725885-0.Travel-Guide-Filter-Hotels), located 1.3km from Santa Ana, perfect for sports enthusiasts. For an exhilarating outing, head to Estadio Nacional Rod Carew, 9.7km away, or Estadio Rommel Fernandez, 11.3km away, both offering thrilling sports events and energetic vibes. **Adventure** Embark on the Honeycreeper Ridge Trail, located 211.3km from Santa Ana, for a scenic hike surrounded by vibrant nature. For a thrilling experience, visit Gatun Eco Adventures, situated 48.3km away, where you can soar through the treetops on an exhilarating zipline ropes course. **Nightlife** Experience the vibrant nightlife in Santa Ana by visiting Crown Casino, just 3.2km away, for thrilling games and romance. For a cultural evening, enjoy a show at the National Theater (0.9.7km away) or Anita Villalaz Theater (1.3km away), both offering family-friendly entertainment and a romantic atmosphere. ### Booking tips and Expedia advantages for Santa Ana When visiting Santa Ana, Panama, consider exploring free attractions like Albrook Shopping Mall and Cinta Costera. To save on accommodation, travel during the off-peak months from September to November, when prices are lower compared to peak times like March and December to January. Tuesdays are typically the cheapest days to stay, while Saturdays are the most expensive. Use Expedia to compare prices and book packages that combine flights and hotels for added savings. Don't forget to filter for eco-certified hotels to find sustainable options that fit your budget. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay around Santa Ana are September to November, where the prices are slightly lower. This is in comparison to March and December to January, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay around Santa Ana is Tuesday. The most expensive day to stay around Santa Ana is Saturday. - **Find cheap hotels on Expedia:** Expedia’s search tool enables you to choose your budget, preferred location, and additional criteria. You can easily sort your results to display prices from lowest to highest, allowing you to find the most affordable hotels right away. Additionally, you can refine your choices by hotel type—select the "Eco-certified" filter to discover sustainable and environmentally-friendly accommodations available for booking. - **Consider bundling your trip:** You can save money by combining your Santa Ana hotel reservation with your flights and activities when you book an Expedia package. ### Find the best attractions near Santa Ana Santa Ana, located in Panama City, is perfect for family and business vacations, offering a rich cultural experience. Visitors can explore historical sites such as the Santa Ana Church and Iglesia Santa Ana, relax at Santa Ana Square, and enjoy scenic views near the canyon. The area's attractions cater to those seeking a blend of history and city life, making it an ideal destination for tourists looking to immerse themselves in local culture. - **[Metropolitan Cathedral of Panama:](https://www.expedia.ca/Metropolitan-Cathedral-Of-Panama-Hotels.0-l6078477-0.Travel-Guide-Filter-Hotels)** Located 805m from Santa Ana, this stunning cathedral showcases remarkable colonial architecture and intricate artwork. It serves as a cultural hub, offering a glimpse into Panama's rich history and religious heritage. - **Ancon Hill:** Just 966m from Santa Ana, Ancon Hill provides breathtaking panoramic views of Panama City and the Panama Canal. This outdoor oasis is perfect for hiking and enjoying nature while immersing yourself in the area's scenic beauty. - **Interoceanic Canal Museum:** Situated 805m away, this museum is dedicated to the history of the Panama Canal. It features fascinating exhibits that highlight the canal's significance, making it a must-visit for culture enthusiasts. ### Best time to go to Santa Ana Visitor numbers around Santa Ana is generally unchanged in popularity throughout the year. The best time to visit Santa Ana can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santa Ana falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around Santa Ana falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain. | **![calendar icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly cloudy icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation rate icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------- | --------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------ | ------------------------------------------------------------------------------------------------------------------ | | January | 78.8°F (26.0°C) | No Rain (Dry) | Mostly Sunny | Slightly High | Slightly High | | February | 79.2°F (26.2°C) | No Rain (Dry) | Mostly Sunny | Slightly High | Average | | March | 79.7°F (26.5°C) | No Rain (Dry) | Mostly Sunny | Average | Slightly High | | April | 80.4°F (26.9°C) | Light Rain | Mostly Sunny | Average | Average | | May | 80.2°F (26.8°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Average | | June | 79.9°F (26.6°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Average | | July | 79.3°F (26.3°C) | Frequent Rain | Mostly Cloudy | Average | Average | | August | 79.2°F (26.2°C) | Frequent Rain | Mostly Cloudy | Average | Average | | September | 79.3°F (26.3°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Slightly Low | | October | 78.6°F (25.9°C) | Frequent Rain | Mostly Cloudy | Average | Slightly Low | | November | 78.3°F (25.7°C) | Frequent Rain | Mostly Cloudy | Average | Slightly Low | | December | 78.6°F (25.9°C) | Light Rain | Mostly Cloudy | Slightly High | Slightly High | ### The nearest major airports for your trip to Santa Ana When visiting Santa Ana, you have convenient access to two major airports. Panama City ([PTY](https://www.expedia.ca/Tocumen-Intl-Airport-Hotels.0-aPTY-0.Travel-Guide-Filter-Hotels)\-Tocumen Intl.) is located 20.9km away, with notable hotels like [The Santa Maria](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information), A Luxury Collection Hotel & Golf Resort, 8.0km from the airport, and [JW Marriott Panama](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information), 16.1km away. Alternatively, Panama City ([PAC](https://www.expedia.ca/Marcos-A-Gelabert-Intl-Airport-Hotels.0-aPAC-0.Travel-Guide-Filter-Hotels)\-Marcos A. Gelabert Intl.) is only 3.2km from Santa Ana, featuring excellent accommodations such as [Waldorf Astoria Panama](https://www.expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information), just 3.2km away, and [Hilton Panama](https://www.expedia.ca/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information), 4.8km away. Transportation services from these hotels to the airports typically include on-request shuttle services, offering ease and comfort for your travel needs. ## Frequently asked questions ### What are the best budget hotels in Santa Ana? > For those seeking a luxurious experience without breaking the bank, [Hotel República](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) presents a charming option with its rooftop terrace providing partial ocean views, superb for relaxing after a day of adventures. This hotel also features free WiFi and air conditioning, ensuring comfort during your stay. Families can take advantage of the area shuttle service to explore Panama City's attractions conveniently. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa Ana hotel booking with Expedia? ### How much is the nightly rate at a Santa Ana hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - [5 Star Hotels in Casco Viejo ](https://www.expedia.ca/5Star-Casco-Viejo-Panama-City-Hotels.s50-n6285189-0.Travel-Guide-Filter-Hotels) - [Hotels near Albrook Shopping Mall ](https://www.expedia.ca/Albrook-Shopping-Mall-Hotels.0-l6159851-0.Travel-Guide-Filter-Hotels) - [Amador Hotels ](https://www.expedia.ca/Amador-Panama-City-Hotels.0-n553248635933392377-0.Travel-Guide-Filter-Hotels) - [Hotels near Avenida Balboa ](https://www.expedia.ca/Avenida-Balboa-Hotels.0-l553248623453290531-0.Travel-Guide-Filter-Hotels) - [Balboa Hotels ](https://www.expedia.ca/Balboa-Panama-City-Hotels.0-n6323179-0.Travel-Guide-Filter-Hotels) - 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