5 Stars Hotels in Panama City, Panamá Province from CA $161

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Our top choices for Panama City 5-star hotels

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (5,094 reviews)
"Great pool and restaurant."
Canada
Terri
The price is CA $205
CA $225 total
includes taxes & fees
Apr 8 - Apr 9
Hotel Riu Plaza Panama

Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,003 reviews)
"Staff was super nice and room was great we also ate on the rooftop and food was great!"
Canada
Tim
The price is CA $266
CA $293 total
includes taxes & fees
Mar 28 - Mar 29
Waldorf Astoria Panama

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,019 reviews)
"Second time staying and it was flawless."
United States
Anthony
The price is CA $270
CA $297 total
includes taxes & fees
Mar 31 - Apr 1
W Panama

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,006 reviews)
"Beautiful hotel, great service. Breakfast buffet is amazing. "
United States
Tamara
The price is CA $322
CA $354 total
includes taxes & fees
Apr 5 - Apr 6
JW Marriott Panama

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very good, (1,004 reviews)
"Beautiful property and amazing staff"
United States
CARMEN
The price is CA $297
CA $327 total
includes taxes & fees
Apr 9 - Apr 10
The Westin Playa Bonita Panama

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (166 reviews)
"Very good hotel, well located. "
United States
Andrés
The price is CA $172
CA $190 total
includes taxes & fees
Apr 5 - Apr 6
Renaissance Panama City Hotel

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (609 reviews)
"Beautiful place"
United States
Jose
The price is CA $514
CA $565 total
includes taxes & fees
Apr 10 - Apr 11
Sofitel Legend Casco Viejo, Panama City

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (1,006 reviews)
"Huge hotel wit"
United States
Katya
The price is CA $241
CA $265 total
includes taxes & fees
Apr 2 - Apr 3
Hilton Panama

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.4 out of 10, Exceptional, (1,006 reviews)
"All was perfect for our Christmas vacation - staff food and rooms - would definitely stay here again"
United States
PROBIR MAYUR
The price is CA $235
CA $259 total
includes taxes & fees
Apr 10 - Apr 11
Bristol Panama, a Registry Collection Hotel

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (673 reviews)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is CA $319
CA $350 total
includes taxes & fees
Apr 10 - Apr 11
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Megapolis Hotel Panamá

Megapolis Hotel Panamá
5.0 star property
San Francisco
8.4 out of 10, Very good, (1,002 reviews)
"Great stay! Very safe!"
United States
MARVIN
Megapolis Hotel Panamá

Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
5.0 star property
Bella Vista
6.2 out of 10, (1,000 reviews)
"It has a nice casino and it's very conveniently located. Breakfast was very good as well. Staff very helpful and attention oriented. Good experience "
United States
Aldo
Waymore Hotel Spa and Casino
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Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

Panoramic view at the Downtown of Panama City - Panama

Top Panama City Hotel Reviews

Find out more about Panama City

Five Star Hotels in Panama City

There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Panama City so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Panama City and get ready to be pampered like never before.

Get a Great Deal on 5-Star Hotels in Panama City

Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places.

Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town.

Make Your Escape to Panama City

The results are in, and Panama City 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Panama City! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Panama City today and settle down in the lap of luxury tomorrow.

Frequently asked questions

What are the best 5-star hotels in Panama City?
Based on Expedia guest reviews, Bristol Panama, a Registry Collection Hotel, W Panama and Hotel Riu Plaza Panama are among the most popular 5-star hotels in Panama City. Featuring top-quality amenities and excellent service, you'll enjoy a luxurious and memorable stay.
How much does it cost to stay in a 5-star hotel in Panama City?
How much you pay for a 5-star hotel in Panama City depends on factors like when you plan to travel and the length of your break. A top tip for bagging the best deal? Use our pricing filters to check out all of the available options for your preferred dates.

  • Search for the lowest price per night from CA $161

What makes a hotel 5 stars in Panama City?
From gourmet dining venues and 24-hour gyms to swimming pools and premium bedding, the 5-star experience in Panama City is all about comfort and luxury. But it requires more than just top-notch conveniences to receive a 5-star rating. Stays must also deliver exceptional guest-focused services like in-room massages, on-site dry cleaning and laundry and a nightly turn-down service.

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