Penonome Vacation Rentals from CA $128: Short-Term Rentals for 2026

Q: What are some of the best vacation home rentals in Penonome?

Chic 1-bedroom with WiFi and AC in enchanting Río Hato : This vacation home rental near Penonome has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings.

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Our top choices for Penonome vacation rentals

1. Cabin with a private pool, horses, nature, and complete tranquility

Penonomé

CA $199 total

includes taxes & fees

Nov 16 - Nov 17

A swimming pool with a water slide, palm trees, and a large building in the background.

2. Apartamento en Playa Blanca Town Center

Rio Hato

Amparo

CA $141 total

includes taxes & fees

Dec 9 - Dec 10

A room with a large window, a bed with multiple pillows, and a view of greenery and mountains.

3. Greenscape 2BR Anton Valley BV4

Valle de Anton

Stefan M.

CA $245 total

includes taxes & fees

Nov 10 - Nov 11

A pool area with a water slide, palm trees, and a clear blue sky.

4. 5-bedroom Beachfront Condo with Ocean View & WiFi – Walk to the Sand!

Rio Hato

Samantha B.

CA $522 total

includes taxes & fees

Nov 15 - Nov 16

A modern living room with a dining area, featuring a wooden dining table, comfortable seating, and a TV in the background.

5. Spacious mountain villa with 5 bedrooms and brand new AC

Anton Valley

Lori D.

CA $478 total

includes taxes & fees

Nov 16 - Nov 17

A beach with palm trees, a sandy shore, and a clear blue sky.

6. WiFi+Pool+10min 2 Surf+Nature+Private+Quiet

La Ermita

HAHN

CA $170 total

includes taxes & fees

Nov 9 - Nov 10

A well-lit building with a stone facade, a tiled roof, and a landscaped garden with a statue and palm trees.

7. Casa de Campo

El Valle de Antón

CA $1,089 total

includes taxes & fees

Nov 9 - Nov 10

A beach with clear blue water and a sandy shore.

8. Panama's Paradise - Playa Blanca - Ocean & Pool View - Huge Saltwater Pool

Rio Hato

CA $308 total

includes taxes & fees

Nov 9 - Nov 10

A swimming pool with a person in the water, surrounded by lounge chairs and a building with windows and plants.

9. Altavida Lodge · 2BR Apt with Garden & Pool · N7

Valle de Anton

"We stayed in the 2‑bedroom suite, and the property itself is absolutely lovely, tucked away at the end of a quiet street. The suite was modern, spotless, spacious, and fully equipped with all the necessities—and more. Although we didn’t use the pool or the outdoor BBQ area, the shared outdoor spaces were beautifully maintained and very inviting. The location is excellent, within walking distance to the restaurants and the downtown area of El Valle de Antón. Unfortunately, a major windstorm swept...

Wallena

CA $238 total

includes taxes & fees

Nov 10 - Nov 11

A water park with two water slides, a pool, and a lifeguard tower.

10. Studio

Río Hato

Irving R.

CA $230 total

includes taxes & fees

Nov 9 - Nov 10

11. Wi-Fi+Piscina+10min a surf+Privada+Tranquila+Naturaleza

Panama Oeste Antes de las Torres

CA $208 total

includes taxes & fees

Nov 9 - Nov 10

12. Close to beaches, mountains, waterfalls. Great for nomads. Quiet/rural town.

Panama Oeste, 00000, PA

CA $202 total

includes taxes & fees

Nov 9 - Nov 10

A large outdoor swimming pool with a tropical setting, surrounded by palm trees and covered seating areas.

13. Nikki Residence Oceanfront Condo with Great Terrace!

Rio Hato

Brandon H.

CA $216 total

includes taxes & fees

Nov 10 - Nov 11

A balcony with wicker furniture overlooking a pool and a distant building.

14. Suite en Playa Blanca Vista Piscina Grande + Playa Cerca

Rio Hato

CA $308 total

includes taxes & fees

Nov 9 - Nov 10

A pool area with lounge chairs, a clear blue pool, and palm trees.

15. Playa Blanca: 3-Bedroom Villa with Private Pool

rio hato

CA $1,468 total

includes taxes & fees

Nov 9 - Nov 10

A spacious room with large windows offering a view of the sea and buildings. There are potted plants and a ceiling fan.

16. 2-bedroom condo in Playa Blanca

Río Hato

CA $166 total

includes taxes & fees

Nov 10 - Nov 11

A living room with a sofa, a coffee table, and a view of a pool and palm trees through a sliding glass door.

17. Luxury Beachfront Getaway in Playa Blanca with Pool and Beach Vibes, Rio Hato.

Río Hato

CA $516 total

includes taxes & fees

Nov 15 - Nov 16

A modern house with a sloped roof, surrounded by dense forest.

18. Glanta: Eco A-Frame Cabin with Heated Jacuzzi in El Valle de Antón

Anton Valley

Annie R.

CA $352 total

includes taxes & fees

Nov 9 - Nov 10

A resort with multiple buildings, a central pool area, and a beach in the background.

19. 2-bedroom, 2-bathroom apartment at Nikki Residences, steps from the sea on Panama's Pacific coast. Pool with weekend bar, fully equipped kitchen, A/C in every room, a workspace and a 15 m² terrace. Long-stay discounts and free weekly cleaning on stay

El Chirú

CA $276 total

includes taxes & fees

Nov 10 - Nov 11

A woman in a black bikini walking on a tiled poolside.

20. Emerald Lagoon Suites

Río Hato

CA $1,463 total

includes taxes & fees

Nov 9 - Nov 10

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Find vacation rentals that suit your style

Top Penonome Hotel Reviews

A resort with a swimming pool, lounge chairs, and a thatched-roof structure.

Hotel Coclé

Penonome

10/10 Excellent

Richard

A pool with clear blue water, surrounded by lush greenery and hills in the background.

La Pintada Inn

Llano Grande

10/10 Excellent

Luke

A patio with wicker chairs, a glass table, and a tiled floor.

Hotel Las Catalinas Antón

Anton

8/10 Good

Hostal trés typique bien situé dans Anton. Accueil sympathique. Les installations sont un peu désuètes mais tout est fonctionnel. La literie (draps et serviettes) gagnerait à être renouvelée. Nous pensions qu'il y avait de la restauration sur place mais ce n'etait pas le cas. Cependant la cuisine etait disponible pour tous. Stationnement disponible sur la rue. Nous y étions lors du weekend de la grande fête chretienne sans l'avoir prevu. Beaucoup d'action jour et nuit mais nous avons...

Sylvie

A bedroom with a large bed, a wooden bench, and a view of a mountainous landscape through large windows.

Nomada Republic Hotel El Valle

El Valle de Anton

10/10 Excellent

Karanbir

A cozy indoor garden with stone flooring, wooden furniture, and various potted plants.

Casa Madre Tierra

Los Llanitos

10/10 Excellent

Our stay at this beautiful hotel was special and unforgettable. From the moment we stepped through the doors, we were transported into a different dimension. The decoration, art, collections and food taste are all over the walls, hallways, space and dimension. Ceaser made our stay even more magical by being so helpful, so kind and attentive. We HIGHLY recommend this hotel and we’d stay there again in a heart beat

Mirella

A swimming pool with lounge chairs and palm trees.

The Buenaventura Golf & Beach Resort Panama, Autograph Collection

El Chiru

10/10 Excellent

Stan

A beach with a palm tree and a clear view of the ocean.

Villa Botero By Casa Mojito B&B

Rio Hato

10/10 Excellent

David

A beach with clear blue water and a small island in the distance.

Acuarela Hostal - Hostel

Rio Hato

10/10 Excellent

Tori-Ann

A resort with a swimming pool, beach, and palm trees.

Grand Decameron Panama, A Trademark Resort

Rio Hato

10/10 Excellent

We were nervous about this place given all the bad reviews, but ended up having a great time and are puzzled by those reviews. Check-in and check-out were smooth, efficient and fast; every staff member we encountered was pleasant and helpful; our room was clean, quiet and had a beautiful ocean view and good balcony; food was not 5-star, but very adequate, diverse and plentiful, with lots of healthy options; the beach is superb and you can walk a long time; the pools are great and were not too...

Micheline

Find out more about Penonome

Everything you need to know about Penonome vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Penonome vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Penonome vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Penonome vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Penonome. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Penonome vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Penonome vacation rentals we have selected for you start as low as CA $128 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Penonome rentals

At Expedia, we put the best Penonome vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Penonome rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Penonome vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Penonome. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently Asked Questions

Can I find vacation rentals in Penonome?

Yes, you can find vacation rentals close to the most popular sights in Penonome, or you can go with a more remote option if you want a relaxing place to stay. Penonome is known for its parks and restaurants. Make sure you have time to check out the museums while you're in the area.

What are some of the best vacation home rentals in Penonome?

Chic 1-bedroom with WiFi and AC in enchanting Río Hato: This vacation home rental near Penonome has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings.

What’s there to see and do in Penonome?

Explore the area and family-friendly sights such as Serpentarium, or get out into nature at a spot like 8 de Diciembre Park. Penonomena History and Tradition Museum and Playa Blanca are a couple of places you'll find in the larger area.

What’s a vacation rental in Penonome like?

Vacation rentals are private properties you can book for short or long periods in Penonome. Vacation rentals provide amenities like laundry facilities and kitchens so you'll have everything you need. If you're concerned about a clean environment, vacation rentals can offer a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you to travel. You'll also have more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great option for small groups.

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Penonome Vacation Rentals

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Penonome vacation rentals

1. Cabin with a private pool, horses, nature, and complete tranquility

2. Apartamento en Playa Blanca Town Center

3. Greenscape 2BR Anton Valley BV4

4. 5-bedroom Beachfront Condo with Ocean View & WiFi – Walk to the Sand!

5. Spacious mountain villa with 5 bedrooms and brand new AC

6. WiFi+Pool+10min 2 Surf+Nature+Private+Quiet

7. Casa de Campo

8. Panama's Paradise - Playa Blanca - Ocean & Pool View - Huge Saltwater Pool

9. Altavida Lodge · 2BR Apt with Garden & Pool · N7

10. Studio

11. Wi-Fi+Piscina+10min a surf+Privada+Tranquila+Naturaleza

12. Close to beaches, mountains, waterfalls. Great for nomads. Quiet/rural town.

13. Nikki Residence Oceanfront Condo with Great Terrace!

14. Suite en Playa Blanca Vista Piscina Grande + Playa Cerca

15. Playa Blanca: 3-Bedroom Villa with Private Pool

16. 2-bedroom condo in Playa Blanca

17. Luxury Beachfront Getaway in Playa Blanca with Pool and Beach Vibes, Rio Hato.

18. Glanta: Eco A-Frame Cabin with Heated Jacuzzi in El Valle de Antón

19. 2-bedroom, 2-bathroom apartment at Nikki Residences, steps from the sea on Panama's Pacific coast. Pool with weekend bar, fully equipped kitchen, A/C in every room, a workspace and a 15 m² terrace. Long-stay discounts and free weekly cleaning on stay

20. Emerald Lagoon Suites

Find vacation rentals that suit your style

Top Penonome Hotel Reviews

Hotel Coclé

10/10 Excellent

Find out more about Penonome

Penonome vacation rentals: An excellent choice for every season

How to find incredible deals on Penonome rentals

Frequently Asked Questions

Can I find vacation rentals in Penonome?

What are some of the best vacation home rentals in Penonome?

What’s there to see and do in Penonome?

What’s a vacation rental in Penonome like?

Explore a world of travel with Expedia