Name: HOTEL ISLA GRANDE
Price range: CA $137

Your Isla Grande Vacation

With a Isla Grande vacation package, say goodbye to endless planning and hello to stress-free adventure. Every detail of your getaway has been taken care of before you go, so you can enjoy each moment discovering this lively city. If taking in the sights is a priority during your trip to Isla Grande, be sure to swing by famous attractions like Isla Mamey and Portobelo National Park. Whoever you're heading away with and whatever you want to spend, your dream Isla Grande vacation is just a few clicks away with Expedia.

Top Isla Grande Vacation Deals

Price found within the past 48 hours. Click for updated prices.

Riande Aeropuerto Hotel & Casino

CA $1,344

per person

Jul 13 - Jul 19

found 1 day ago

Roundtrip flight included

Montreal (YMQ) to Panama City (PTY)

8.4/10 Very Good! (1,830 reviews)

Pool was and and everything was very clean and good food too. Everything has been improved from 3 years ago. Nice friendly staff. Two negatives, outdoor hot tub was colder than the pool, but pool was perfect. Outdoor bar, restaurant or no where could you charge anything to your room. Hard to to have cash when your at a swim up bar.

Reviewed on May 26, 2026

Central Hotel Panama Casco Viejo

Casco Viejo

CA $1,619

per person

Jul 13 - Jul 19

found 1 day ago

Roundtrip flight included

Montreal (YMQ) to Panama City (PTY)

9.2/10 Wonderful! (1,004 reviews)

The location is great !, Great food and service !

Reviewed on May 29, 2026

Megapolis Hotel Panamá

San Francisco

CA $1,459

per person

Aug 19 - Aug 25

found 16 hours ago

Roundtrip flight included

Toronto (YTO) to Panama City (PTY)

8.4/10 Very Good! (1,538 reviews)

I love my stay, very convenient for everything, shopping, close by red bus stop and airport!!!

Reviewed on Jun 1, 2026

Casa Mallet by Wynwood House

Casco Viejo

CA $1,924

per person

Aug 14 - Aug 21

found 4 hours ago

Roundtrip flight included

Montreal (YUL) to Panama City (PTY)

9.8/10 Exceptional! (27 reviews)

In the middle of the old town, lovely rooftop. Beautiful apartment. Easy check in. WhatsApp line is available if anything was needed or if we had questions.

Reviewed on Mar 12, 2026

Las Clementinas

Casco Viejo

CA $1,590

per person

Aug 19 - Aug 25

found 16 hours ago

Roundtrip flight included

Toronto (YTO) to Panama City (PTY)

9.4/10 Exceptional! (189 reviews)

Best location. Beautiful heritage place and lovely restaurant attached.

Reviewed on Jun 1, 2026

Ready to book your vacation to Isla Grande?

Choose your dates

Isla Grande Hotel Deals

Ordovician Beach Resort

Isla Grande Isla Grande Colon

CA $593

CA $656 total

Jun 5 - Jun 6

includes taxes & fees

10/10 Exceptional! (9 reviews)

"The resort was outstanding. It exceeded expectations in every way. The service was the best we had in Panama. The cocktails were fun and the food was delicious and they have a vegan menu. We stayed in a king room and it was very private, pristine and well appointed."

Reviewed on Feb 21, 2026

Hotel Cocotal

La Guaira Isla Grande Provincia de Colón

Fully refundableReserve now, pay when you stay

CA $80

CA $149 total

Jun 4 - Jun 5

includes taxes & fees

HOTEL ISLA GRANDE

Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province

CA $137

CA $151 total

Jun 4 - Jun 5

includes taxes & fees

See all 58 properties in Isla Grande

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.