Isla Grande Vacation Packages
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Your Isla Grande Vacation
With a Isla Grande vacation package, say goodbye to endless planning and hello to stress-free adventure. Every detail of your getaway has been taken care of before you go, so you can enjoy each moment discovering this lively city. If taking in the sights is a priority during your trip to Isla Grande, be sure to swing by famous attractions like Isla Mamey and Portobelo National Park. Whoever you're heading away with and whatever you want to spend, your dream Isla Grande vacation is just a few clicks away with Expedia.
Top Isla Grande Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Megapolis Hotel Panamá
San Francisco
Price was CA $2,278, price is now CA $1,459 per person
CA $1,459
per person
Aug 19 - Aug 25
found 23 hours ago
Roundtrip flight included
Toronto (YTO) to Panama City (PTY)
8.4/10 Very Good! (1,538 reviews)
Rooms were great. We had a balcony room, great view! I love that there were food options in the hotel and you could walk right over to the outlet mall! Great location. Uber rides were so easy. Breakfast being included was such a plus and it was tasty!! I would definitely stay here again! And the shower!!!! Always had hot water! It was relaxing. Along with the ice cold room AC. We will be back!
Reviewed on Jun 3, 2026
Central Hotel Panama Casco Viejo
Casco Viejo
Price was CA $2,848, price is now CA $1,466 per person
CA $1,466
per person
Aug 19 - Aug 25
found 23 hours ago
Roundtrip flight included
Toronto (YTO) to Panama City (PTY)
9.2/10 Wonderful! (1,004 reviews)
The staff were so helpful and friendly. Great location and atmosphere.
Reviewed on Jun 3, 2026
Casa Mallet by Wynwood House
Casco Viejo
Price was CA $2,096, price is now CA $1,494 per person
CA $1,494
per person
Aug 23 - Aug 28
found 4 hours ago
Roundtrip flight included
Toronto (YTO) to Panama City (PTY)
9.8/10 Exceptional! (27 reviews)
In the middle of the old town, lovely rooftop. Beautiful apartment. Easy check in. WhatsApp line is available if anything was needed or if we had questions.
Reviewed on Mar 12, 2026
Las Clementinas
Casco Viejo
Price was CA $2,174, price is now CA $1,590 per person
CA $1,590
per person
Aug 19 - Aug 25
found 23 hours ago
Roundtrip flight included
Toronto (YTO) to Panama City (PTY)
9.4/10 Exceptional! (189 reviews)
Best location. Beautiful heritage place and lovely restaurant attached.
Reviewed on Jun 1, 2026
Yoo by Wynwood House
Calidonia
Price was CA $2,049, price is now CA $1,537 per person
CA $1,537
per person
Aug 14 - Aug 21
found 11 hours ago
Roundtrip flight included
Montreal (YUL) to Panama City (PTY)
9.4/10 Exceptional! (6 reviews)
Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone.
Reviewed on Jul 26, 2025
Isla Grande Hotel Deals
Ordovician Beach Resort
Isla Grande Isla Grande Colon
The price is CA $593 per night from Jun 5 to Jun 6
CA $593
CA $656 total
Jun 5 - Jun 6
includes taxes & fees
10/10 Exceptional! (9 reviews)
"The resort was outstanding. It exceeded expectations in every way. The service was the best we had in Panama. The cocktails were fun and the food was delicious and they have a vegan menu. We stayed in a king room and it was very private, pristine and well appointed."
Reviewed on Feb 21, 2026
Hotel Cocotal
La Guaira Isla Grande Provincia de Colón
Fully refundableReserve now, pay when you stay
The price is CA $80 per night from Jun 8 to Jun 9
CA $80
CA $149 total
Jun 8 - Jun 9
includes taxes & fees
HOTEL ISLA GRANDE
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
The price is CA $137 per night from Jun 5 to Jun 6
CA $137
CA $151 total
Jun 5 - Jun 6
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.