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Hotels in Medical Center Area, Boston

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Our top choices for Medical Center Area hotels

1. The Inn at Longwood Medical

The Inn at Longwood Medical
3.5 star property
Medical Center Area
8.4 out of 10, Very good, (1,000 reviews)
"Clean rooms, nice staff"
United States
Stephen
The price is CA $268
CA $353 total
includes taxes & fees
Nov 24 - Nov 25
The Inn at Longwood Medical

2. Arcadian Hotel

Arcadian Hotel
3.5 star property
1.2 km from Medical Center Area
8.2 out of 10, Very good, (4,457 reviews)
"Great location and loved being there."
United States
Seana
The price is CA $168
CA $235 total
includes taxes & fees
Nov 9 - Nov 10
Arcadian Hotel

3. Hyatt Regency Boston/Cambridge

Hyatt Regency Boston/Cambridge
4.0 star property
1.7 km from Medical Center Area
9.0 out of 10, Wonderful, (2,713 reviews)
"Great stay"
United States
Dawn
The price is CA $177
CA $247 total
includes taxes & fees
Nov 24 - Nov 25
Hyatt Regency Boston/Cambridge

4. The Verb Hotel

The Verb Hotel
3.5 star property
0.9 km from Medical Center Area
9.6 out of 10, Exceptional, (2,156 reviews)
"Great location, friendly staff, and an awesome vibe at this hotel."
United States
Justin
The price is CA $253
CA $360 total
includes taxes & fees
Nov 23 - Nov 24
The Verb Hotel

5. Hampton Inn & Suites Boston Crosstown Center

Hampton Inn & Suites Boston Crosstown Center
3.0 star property
2.6 km from Medical Center Area
8.0 out of 10, Very good, (1,900 reviews)
"it was great i love the staff the fact that they offer breakfast, and the location is perfect."
United States
Jennifer
The price is CA $142
CA $165 total
includes taxes & fees
Nov 22 - Nov 23
Hampton Inn & Suites Boston Crosstown Center

6. Hotel Commonwealth

Hotel Commonwealth
4.5 star property
Fenway–Kenmore, 1.3 km from Medical Center Area
9.4 out of 10, Exceptional, (2,400 reviews)
"It was a very enjoyable stay"
United States
Patricia
The price is CA $220
CA $321 total
includes taxes & fees
Nov 24 - Nov 25
Hotel Commonwealth

7. Iris Hotel Boston

Iris Hotel Boston
4.0 star property
1.6 km from Medical Center Area
9.4 out of 10, Exceptional, (784 reviews)
"Great place to stay"
United States
Allison
The price is CA $308
CA $344 total
includes taxes & fees
Nov 2 - Nov 3
Iris Hotel Boston

8. Copley House

Copley House
3.0 star property
Prudential - St. Botolph, 2 km from Medical Center Area
9.2 out of 10, Wonderful, (2,304 reviews)
"Fantastic location in Back Bay."
United States
Maryann
The price is CA $385
CA $442 total
includes taxes & fees
Oct 30 - Oct 31
Copley House

9. citizenM Boston Back Bay

citizenM Boston Back Bay
4.0 star property
1.6 km from Medical Center Area
9.2 out of 10, Wonderful, (3,320 reviews)
"The location and style of hotel was impressive."
United States
Heather
The price is CA $188
CA $219 total
includes taxes & fees
Nov 24 - Nov 25
citizenM Boston Back Bay

10. Lark Hotels 907 Main

Lark Hotels 907 Main
2.0 star property
2.8 km from Medical Center Area
9.4 out of 10, Exceptional, (340 reviews)
"Great location, very friendly and helpful staff"
United States
Sarah
The price is CA $202
CA $235 total
includes taxes & fees
Nov 22 - Nov 23
Lark Hotels 907 Main

11. The Midtown Hotel MOD Collection by Sonesta

The Midtown Hotel MOD Collection by Sonesta
3.0 star property
Prudential - St. Botolph, 1.8 km from Medical Center Area
8.0 out of 10, Very good, (1,320 reviews)
"first time staying and it was nice!"
United States
Andrea
The price is CA $196
CA $228 total
includes taxes & fees
Nov 23 - Nov 24
The Midtown Hotel MOD Collection by Sonesta

12. Hilton Boston Park Plaza

Hilton Boston Park Plaza
4.0 star property
Bay Village, 3.1 km from Medical Center Area
8.4 out of 10, Very good, (2,960 reviews)
"Great location, great food and drinks"
United States
Lena M
The price is CA $177
CA $264 total
includes taxes & fees
Nov 24 - Nov 25
Hilton Boston Park Plaza

13. Charlesmark Hotel

Charlesmark Hotel
4.0 star property
Back Bay East, 2.4 km from Medical Center Area
8.8 out of 10, Excellent, (1,211 reviews)
"Great staff very clean and fun place to stay."
United States
allen
The price is CA $163
CA $187 total
includes taxes & fees
Nov 22 - Nov 23
Charlesmark Hotel

14. Residence Inn by Marriott Boston Downtown / South End

Residence Inn by Marriott Boston Downtown / South End
3.0 star property
1.9 km from Medical Center Area
8.8 out of 10, Excellent, (1,005 reviews)
"Wonderful hotel! Beautiful rooms and walking distance to public transport!"
United States
Taylor
The price is CA $206
CA $239 total
includes taxes & fees
Nov 22 - Nov 23
Residence Inn by Marriott Boston Downtown / South End

15. Copley Square Hotel, a FOUND Hotel

Copley Square Hotel, a FOUND Hotel
4.0 star property
Prudential - St. Botolph, 2.3 km from Medical Center Area
8.6 out of 10, Excellent, (4,007 reviews)
"Perfect little hotel for our weekend in Boston!"
United States
Elena
The price is CA $154
CA $180 total
includes taxes & fees
Nov 24 - Nov 25
Copley Square Hotel, a FOUND Hotel

16. The Eliot Hotel

The Eliot Hotel
4.0 star property
1.7 km from Medical Center Area
9.6 out of 10, Exceptional, (1,000 reviews)
"Great place. Great location. Friendly staff"
United States
Giora
The price is CA $339
CA $394 total
includes taxes & fees
Nov 22 - Nov 23
The Eliot Hotel

17. Staypineapple, A Delightful Hotel, South End

Staypineapple, A Delightful Hotel, South End
3.0 star property
2.9 km from Medical Center Area
9.0 out of 10, Wonderful, (1,001 reviews)
"Exceptional staff, cute design, great location!"
United States
Thomas
The price is CA $175
CA $244 total
includes taxes & fees
Nov 20 - Nov 21
Staypineapple, A Delightful Hotel, South End

18. Boston Marriott Copley Place

Boston Marriott Copley Place
4.0 star property
Prudential - St. Botolph, 2.2 km from Medical Center Area
9.4 out of 10, Exceptional, (1,870 reviews)
"Great stay"
United States
Rodrigo
The price is CA $225
CA $320 total
includes taxes & fees
Nov 22 - Nov 23
Boston Marriott Copley Place

19. Four Points by Sheraton Boston Newton

Four Points by Sheraton Boston Newton
3.5 star property
7.2 km from Medical Center Area
8.4 out of 10, Very good, (2,686 reviews)
"Great place to stay for our weekend in Boston!"
United States
Ellen
The price is CA $130
CA $145 total
includes taxes & fees
Nov 22 - Nov 23
Four Points by Sheraton Boston Newton

20. Oasis Guest House

Oasis Guest House
2.5 star property
Fenway–Kenmore, 1.5 km from Medical Center Area
9.4 out of 10, Exceptional, (1,556 reviews)
"Great location , clean rooms and lovely breakfast"
Canada
Phillip Danny
The price is CA $218
CA $250 total
includes taxes & fees
Nov 22 - Nov 23
Oasis Guest House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Medical Center Area

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A hotel with a prominent sign reading "The Inn."
The Inn at Longwood Medical
3.5 star property
8.4
Very good
1,000 reviews
View
An outdoor pool area with lounge chairs and umbrellas, surrounded by buildings.
The Verb Hotel
3.5 star property
9.6
Exceptional
2,156 reviews
View
A modern hotel lobby with a high ceiling, multiple seating areas, and a large window overlooking the sky.
Arcadian Hotel
3.5 star property
8.2
Very good
4,457 reviews
View
A multi-story hotel with a distinctive stepped design, featuring illuminated signage and a reflection in the water.
Hyatt Regency Boston/Cambridge
4.0 star property
9.0
Wonderful
2,713 reviews
View
A hotel room with two beds, a round table with chairs, a TV, and large windows with curtains.
Iris Hotel Boston
4.0 star property
9.4
Exceptional
784 reviews
View

Hotels recommended for families in Medical Center Area

Where to stay in Medical Center Area

Find the best Medical Center Area areas and neighborhoods for the activities you enjoy most.

Downtown Boston

Densely packed with highrise buildings, this area boasts landmarks like Custom House Tower and is close to Quincy Market, Faneuil Hall, and the Old State House. Find headquarters of major banks, hotels, and investment firms here.

Back Bay

Victorian brownstone homes and cultural institutions like the Boston Public Library define this area. Shop at Newbury Street, Prudential Center, and Copley Place, or explore sights like Trinity Church and the John Hancock Tower.

Seaport District

Experience a transformed industrial area with office towers, innovation labs, and 78 restaurants. Visit the Institute of Contemporary Art and easily access Downtown Boston via the Evelyn Moakley Bridge.

Beacon Hill

Historic Federal-style rowhouses, gaslit streets, and brick sidewalks create a charming atmosphere. Explore the Boston African American National Historic Site, shop on Charles Street, and easily access MBTA stations.

North End

Indulge in Italian cuisine at numerous restaurants and bakeries, explore historic sites like Old North Church and Paul Revere House, and enjoy performances at NEMPAC and Improv Asylum Theater. Easily accessible via MBTA lines, buses, and ferries.

Top Medical Center Area Hotel Reviews

Frequently asked questions

What are the best hotels in Medical Center Area that travellers recommend?
For highly recommended hotels in the Medical Centre Area, consider The Eliot Hotel, Raffles Boston, The Colonnade Hotel Back Bay, Iris Hotel Boston, and Mandarin Oriental, Boston.

The 4-star The Eliot Hotel, with an impressive 9.6 rating, is frequently praised for its spacious, clean rooms and friendly, helpful staff. Guests appreciate the beautiful suites and excellent service. It is located near The Fens and the Isabella Stewart Gardner Museum.

Raffles Boston, a 5-star hotel rated 9.6, offers exceptional service and attentive staff. Guests enjoy the nice rooms, and its convenient location is a highlight, being just 0.1 km from 200 Clarendon Street. It also features deep soaking bathtubs and rainfall showerheads.

Another excellent choice is The Colonnade Hotel Back Bay, a 4-star hotel with a 9.2 rating. This hotel is commended for its excellent location, friendly staff, and spacious, clean rooms. It also offers convenient parking and great service. The hotel is close to the Minuteman Bikeway.

The 4-star Iris Hotel Boston, rated 9.4, is known for its comfortable, great rooms and excellent amenities. The staff are friendly and helpful, and guests consistently highlight the fantastic service. It is conveniently located near the Brookline Farmers Market.

Finally, the 5-star Mandarin Oriental, Boston, with a 9.4 rating, receives high praise for its amazing staff who are always willing to help. Guests appreciate the perfect, clean rooms and the excellent location. It is situated close to 200 Clarendon Street and The Fens.
What are the best family hotels in Medical Center Area?
For families visiting the Medical Centre Area, several excellent hotels offer amenities and features to ensure a comfortable stay, including Raffles Boston, The Lenox Hotel Boston, Residence Inn by Marriott Boston Back Bay/Fenway, and Four Seasons Hotel One Dalton Street, Boston.

Raffles Boston is a 5-star hotel with an outstanding 9.6 rating. This hotel provides connecting rooms, books and games for children, kids' meals, children's bathrobes, complimentary cribs, and onsite babysitting services. Guests frequently praise the attentive staff, nice rooms, and convenient location, with Innovation District just 2.9 km away and Gibson House Museum 0.7 km away.

Another highly-rated option is The Lenox Hotel Boston, a 4.5-star hotel with a 9.6 rating. It offers complimentary cribs, kids' meals in the restaurant, onsite babysitting, connecting rooms, and rollaway extra beds. The hotel also features a child-friendly window design for added peace of mind. Customers appreciate the friendly and helpful staff, excellent location, and clean rooms.

The 3-star Residence Inn by Marriott Boston Back Bay/Fenway, rated 9.2, is a great choice for families. It provides complimentary rollaway extra beds and cribs, sofa beds, connecting rooms, and a pool. It's conveniently located near The Fens, just 0.3 km away, and the Isabella Stewart Gardner Museum, 0.8 km away. Guests frequently mention the clean rooms, friendly staff, and great breakfast.

The 5-star Four Seasons Hotel One Dalton Street, Boston, with a 9.6 rating, is another excellent family-friendly option. It offers complimentary rollaway extra beds and cribs, connecting rooms, a pool, sofa beds, and kids' meals in the restaurant. The hotel is praised for its exceptional staff, great location, and clean rooms. It is 1.5 km from The Fens and 1.3 km from Gibson House Museum.
What are the best 5-star hotels in Medical Center Area?
For exceptional 5-star accommodation in the Medical Centre Area, consider the Raffles Boston, Mandarin Oriental, Boston, and the Four Seasons Hotel One Dalton Street, Boston.

The 5-star Raffles Boston, with an outstanding 9.6 rating, offers luxurious features such as deep soaking bathtubs, rainfall showerheads, and designer toiletries. Guests frequently praise the attentive staff and great rooms. The hotel also provides 24-hour room service and valet parking, and is conveniently located near 200 Clarendon Street, just 0.1 km away.

Another excellent choice is the 5-star Mandarin Oriental, Boston, rated 9.4. This hotel boasts Frette Italian sheets and premium bedding for a truly comfortable stay, along with 24-hour room service and valet parking. Guests consistently praise the amazing staff and excellent location, with 200 Clarendon Street just 0.6 km away.

The 5-star Four Seasons Hotel One Dalton Street, Boston, also with a 9.6 rating, offers a refined experience. It features deep soaking bathtubs, designer toiletries, and premium bedding. The hotel also provides 24-hour room service and valet parking. Travellers regularly highlight the exceptional staff, great facilities, and clean rooms. It is also conveniently located near 200 Clarendon Street, 0.9 km away.
What are the best spa hotels in Medical Center Area?
For an exceptional spa experience in the Medical Centre Area, consider the Mandarin Oriental, Boston, Raffles Boston, Four Seasons Hotel One Dalton Street, Boston, or the Iris Hotel Boston.

The 5-star Mandarin Oriental, Boston, with an impressive 9.4 rating, offers an extensive spa experience including deep tissue, hot stone, and Swedish massages, hydrotherapy treatments, and a steam room. Guests consistently praise the amazing and always willing to help staff, the excellent location, and the perfect, clean rooms. It is conveniently located near 200 Clarendon Street and the Christian Science Plaza.

Another outstanding option is the 5-star Raffles Boston, boasting an excellent 9.6 rating. This hotel provides a full-service spa with a hot tub, steam room, and dedicated treatment rooms for massages and body treatments. Reviewers frequently highlight the attentive staff, nice rooms, and convenient location, being very close to 200 Clarendon Street and Gallery Naga.

The 5-star Four Seasons Hotel One Dalton Street, Boston, also with a 9.6 rating, features a full-service spa offering body wraps, scrubs, manicures, pedicures, and a steam room. Guests consistently praise the exceptional staff, great location, and clean rooms. It's ideally situated near the Christian Science Plaza and Prudential Tower.

For a highly-rated 4-star option, the Iris Hotel Boston, with a 9.4 rating, provides a range of spa services including deep tissue and hot stone massages, aromatherapy, and facial treatments. Travellers appreciate the friendly and helpful staff, comfortable rooms, and excellent location, being close to the John Fitzgerald Kennedy National Historic Site.
What are the top boutique hotels in Medical Center Area?
For a top boutique hotel in the Medical Centre Area, The Westin Copley Place, Boston, a Marriott Hotel is an excellent choice.

This 4-star hotel, with a 9.2 rating, is known for its Art Deco design and offers premium bedding for a comfortable stay. Guests often highlight the convenient location and the friendly, helpful staff. The hotel provides excellent fitness facilities, including a 24-hour fitness centre and on-site yoga and fitness classes. It is also very close to 200 Clarendon Street, just 0.2 km away, and the Prudential Tower, 0.4 km away.
What are the most romantic hotels in Medical Center Area for couples?
For a romantic stay in the Medical Centre Area, several highly-rated hotels offer exceptional experiences for couples, including The Eliot Hotel, Four Seasons Hotel One Dalton Street, Boston, Raffles Boston, and Iris Hotel Boston.

The 4-star Eliot Hotel, with a superb 9.6 rating, is a wonderful choice for couples. It features elegant suites, premium bedding, and designer toiletries. Guests frequently praise the excellent staff and spacious, clean rooms. Dining options for couples are available, and the hotel provides valet parking. It is also conveniently located near the Prudential Tower, just 0.5 km away, and the Christian Science Plaza, 0.6 km away.

Another outstanding option is the 5-star Four Seasons Hotel One Dalton Street, Boston, which also boasts a 9.6 rating. This hotel is situated in a shopping district and offers luxurious amenities such as deep soaking bathtubs, designer toiletries, and 24-hour room service. Couples can enjoy treatment rooms, and guests consistently praise the exceptional staff and facilities. The hotel is very close to the Prudential Tower, only 0.2 km away, and the Christian Science Plaza, 0.3 km away.

The 5-star Raffles Boston, rated 9.6, provides a truly luxurious and romantic experience. It features deep soaking bathtubs, rainfall showerheads, designer toiletries, and fireplaces. Couples can indulge in spa amenities like a hot tub, sauna, and couples treatment rooms. Guests frequently highlight the attentive staff and convenient location. It is just 0.1 km from 200 Clarendon Street and 0.6 km from the Prudential Tower.

Finally, the 4-star Iris Hotel Boston, with a 9.4 rating, is another excellent choice for couples. This hotel offers premium bedding, Frette Italian sheets, champagne service, and private indoor hot tubs for a truly intimate experience. Guests appreciate the friendly and helpful staff, comfortable rooms, and excellent location. It is located 0.7 km from the John Fitzgerald Kennedy National Historic Site.
When is the best time to go to Medical Center Area?
The best time to visit the Medical Center Area is during the late spring (May to June) or early autumn (September to October).

These periods offer pleasant weather, with moderate temperatures and less humidity than the peak summer months. You'll find it comfortable for walking around and exploring the area's amenities. Additionally, these shoulder seasons generally mean fewer crowds compared to the busiest summer travel period, leading to a more relaxed experience.

For those visiting for medical appointments, these months also generally provide a calmer environment around the hospitals and clinics.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Medical Center Area hotel for you.
How much is the nightly rate at a Medical Center Area hotel?
Hotel prices in Medical Center Area often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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