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Hotels in Medical Center Area, Boston

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Our top choices for Medical Center Area hotels

1. The Inn at Longwood Medical

The Inn at Longwood Medical
3.5 star property
Medical Center Area
8.4 out of 10, Very good, (1,000 reviews)
"The rooms and facilities were clean and comfortable. Great location to the Longwood area of Boston colleges and activities."
United States
Lynn
The price is CA $368
CA $469 total
includes taxes & fees
Oct 30 - Oct 31
The Inn at Longwood Medical

2. Arcadian Hotel

Arcadian Hotel
3.5 star property
1.2 km from Medical Center Area
8.2 out of 10, Very good, (4,427 reviews)
"Great stay"
United States
Steven
The price is CA $224
CA $297 total
includes taxes & fees
Nov 1 - Nov 2
Arcadian Hotel

3. The Verb Hotel

The Verb Hotel
3.5 star property
0.9 km from Medical Center Area
9.6 out of 10, Exceptional, (2,134 reviews)
"Great location"
United States
Vincent
The price is CA $255
CA $363 total
includes taxes & fees
Nov 1 - Nov 2
The Verb Hotel

4. Copley House

Copley House
3.0 star property
Prudential - St. Botolph, 2 km from Medical Center Area
9.2 out of 10, Wonderful, (2,289 reviews)
"Very nice and clean property, easy check-in, great location. Would absolutely stay here again!"
United States
Ian
The price is CA $364
CA $419 total
includes taxes & fees
Oct 30 - Oct 31
Copley House

5. Hilton Boston Park Plaza

Hilton Boston Park Plaza
4.0 star property
Bay Village, 3.1 km from Medical Center Area
8.4 out of 10, Very good, (2,980 reviews)
"Second time staying at the Boston Park Plaza hotel and it did not disappoint. Great location close to all the major tourist spots, hotel has everything you need."
Canada
Seline
The price is CA $302
CA $410 total
includes taxes & fees
Oct 30 - Oct 31
Hilton Boston Park Plaza

6. citizenM Boston Back Bay

citizenM Boston Back Bay
4.0 star property
1.6 km from Medical Center Area
9.4 out of 10, Exceptional, (3,254 reviews)
"Such a great, comfy vibe. Loved staying here!"
United States
Melissa
The price is CA $293
CA $341 total
includes taxes & fees
Nov 1 - Nov 2
citizenM Boston Back Bay

7. Iris Hotel Boston

Iris Hotel Boston
4.0 star property
1.6 km from Medical Center Area
9.4 out of 10, Exceptional, (745 reviews)
"Great place to stay"
United States
Allison
The price is CA $367
CA $410 total
includes taxes & fees
Nov 1 - Nov 2
Iris Hotel Boston

8. Lark Hotels 907 Main

Lark Hotels 907 Main
2.0 star property
2.8 km from Medical Center Area
9.4 out of 10, Exceptional, (315 reviews)
"Stay was great, very clean!"
United States
Katherine
The price is CA $265
CA $307 total
includes taxes & fees
Nov 1 - Nov 2
Lark Hotels 907 Main

9. Hotel Commonwealth

Hotel Commonwealth
4.5 star property
Fenway–Kenmore, 1.3 km from Medical Center Area
9.4 out of 10, Exceptional, (2,354 reviews)
"Amazing hotel and location"
United States
Cheryl
The price is CA $412
CA $547 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Commonwealth

10. Hampton Inn & Suites Boston Crosstown Center

Hampton Inn & Suites Boston Crosstown Center
3.0 star property
2.6 km from Medical Center Area
8.0 out of 10, Very good, (1,882 reviews)
"Great place and great Cuban dinner and breakfast!"
United States
Karin
The price is CA $240
CA $280 total
includes taxes & fees
Nov 2 - Nov 3
Hampton Inn & Suites Boston Crosstown Center

11. Residence Inn by Marriott Boston Downtown / South End

Residence Inn by Marriott Boston Downtown / South End
3.0 star property
1.9 km from Medical Center Area
8.8 out of 10, Excellent, (1,000 reviews)
"Very polite staff and daily breakfast offered varied selection."
United States
Denise
The price is CA $290
CA $338 total
includes taxes & fees
Nov 1 - Nov 2
Residence Inn by Marriott Boston Downtown / South End

12. The Midtown Hotel MOD Collection by Sonesta

The Midtown Hotel MOD Collection by Sonesta
3.0 star property
Prudential - St. Botolph, 1.8 km from Medical Center Area
8.0 out of 10, Very good, (1,206 reviews)
"It was a wonderful stay. Great staff and great location."
United States
Jody
The price is CA $325
CA $379 total
includes taxes & fees
Nov 1 - Nov 2
The Midtown Hotel MOD Collection by Sonesta

13. The Westin Copley Place, Boston, a Marriott Hotel

The Westin Copley Place, Boston, a Marriott Hotel
4.0 star property
Prudential - St. Botolph, 2.4 km from Medical Center Area
9.2 out of 10, Wonderful, (1,517 reviews)
"Wonderful location and lovely rooms."
United States
Jean
The price is CA $385
CA $507 total
includes taxes & fees
Oct 30 - Oct 31
The Westin Copley Place, Boston, a Marriott Hotel

14. Four Points by Sheraton Boston Newton

Four Points by Sheraton Boston Newton
3.5 star property
7.2 km from Medical Center Area
8.4 out of 10, Very good, (2,690 reviews)
"Was a great stay."
United States
Samantha
The price is CA $162
CA $181 total
includes taxes & fees
Nov 1 - Nov 2
Four Points by Sheraton Boston Newton

15. Moxy Boston Downtown

Moxy Boston Downtown
3.5 star property
Bay Village, 3.5 km from Medical Center Area
8.8 out of 10, Excellent, (1,222 reviews)
"Great place and nice staff"
Canada
Mark Felix
The price is CA $289
CA $395 total
includes taxes & fees
Oct 30 - Oct 31
Moxy Boston Downtown

16. Hampton Inn & Suites Watertown Boston

Hampton Inn & Suites Watertown Boston
2.5 star property
5.4 km from Medical Center Area
9.2 out of 10, Wonderful, (1,198 reviews)
"My second stay here - convenient and nice area to eat and shop. Hotel was clean and quiet - staff friendly"
United States
Gina
The price is CA $228
CA $255 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn & Suites Watertown Boston

17. Oasis Guest House

Oasis Guest House
2.5 star property
Fenway–Kenmore, 1.5 km from Medical Center Area
9.4 out of 10, Exceptional, (1,529 reviews)
"The location is great and the staff is friendly."
United States
Gardenia
The price is CA $304
CA $349 total
includes taxes & fees
Oct 27 - Oct 28
Oasis Guest House

18. Studio Allston Hotel

Studio Allston Hotel
4.0 star property
3.9 km from Medical Center Area
8.6 out of 10, Excellent, (1,339 reviews)
"Rooms were clean, breakfast was good, convenient to the bus stop, calm location, would stay here again."
United States
Crystal
The price is CA $195
CA $285 total
includes taxes & fees
Nov 1 - Nov 2
Studio Allston Hotel

19. The Revolution Hotel

The Revolution Hotel
3.5 star property
2.8 km from Medical Center Area
9.0 out of 10, Wonderful, (2,939 reviews)
"A great place to stay in Boston!"
United States
Austin
The price is CA $204
CA $237 total
includes taxes & fees
Nov 1 - Nov 2
The Revolution Hotel

20. Copley Square Hotel, a FOUND Hotel

Copley Square Hotel, a FOUND Hotel
4.0 star property
Prudential - St. Botolph, 2.3 km from Medical Center Area
8.6 out of 10, Excellent, (4,003 reviews)
"Perfect little hotel for our weekend in Boston!"
United States
Elena
The price is CA $302
CA $352 total
includes taxes & fees
Nov 1 - Nov 2
Copley Square Hotel, a FOUND Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical Center Area

Find the best Medical Center Area areas and neighborhoods for the activities you enjoy most.

Downtown Boston

Densely packed with highrise buildings, this area boasts landmarks like Custom House Tower and is close to Quincy Market, Faneuil Hall, and the Old State House. Find headquarters of major banks, hotels, and investment firms here.

Back Bay

Victorian brownstone homes and cultural institutions like the Boston Public Library define this area. Shop at Newbury Street, Prudential Center, and Copley Place, or explore sights like Trinity Church and the John Hancock Tower.

Seaport District

Experience a transformed industrial area with office towers, innovation labs, and 78 restaurants. Visit the Institute of Contemporary Art and easily access Downtown Boston via the Evelyn Moakley Bridge.

Beacon Hill

Historic Federal-style rowhouses, gaslit streets, and brick sidewalks create a charming atmosphere. Explore the Boston African American National Historic Site, shop on Charles Street, and easily access MBTA stations.

North End

Indulge in Italian cuisine at numerous restaurants and bakeries, explore historic sites like Old North Church and Paul Revere House, and enjoy performances at NEMPAC and Improv Asylum Theater. Easily accessible via MBTA lines, buses, and ferries.

Top Medical Center Area Hotel Reviews

Frequently asked questions

What are the best hotels in Medical Center Area that travellers recommend?
For highly recommended hotels in the Medical Centre Area, consider The Eliot Hotel, Raffles Boston, The Colonnade Hotel Back Bay, Iris Hotel Boston, and Mandarin Oriental, Boston.

The 4-star The Eliot Hotel, with an impressive 9.6 rating, is frequently praised for its spacious, clean rooms and friendly, helpful staff. Guests appreciate the beautiful suites and excellent service. It is located near The Fens and the Isabella Stewart Gardner Museum.

Raffles Boston, a 5-star hotel rated 9.6, offers exceptional service and attentive staff. Guests enjoy the nice rooms, and its convenient location is a highlight, being just 0.1 km from 200 Clarendon Street. It also features deep soaking bathtubs and rainfall showerheads.

Another excellent choice is The Colonnade Hotel Back Bay, a 4-star hotel with a 9.2 rating. This hotel is commended for its excellent location, friendly staff, and spacious, clean rooms. It also offers convenient parking and great service. The hotel is close to the Minuteman Bikeway.

The 4-star Iris Hotel Boston, rated 9.4, is known for its comfortable, great rooms and excellent amenities. The staff are friendly and helpful, and guests consistently highlight the fantastic service. It is conveniently located near the Brookline Farmers Market.

Finally, the 5-star Mandarin Oriental, Boston, with a 9.4 rating, receives high praise for its amazing staff who are always willing to help. Guests appreciate the perfect, clean rooms and the excellent location. It is situated close to 200 Clarendon Street and The Fens.
What are the best family hotels in Medical Center Area?
For families visiting the Medical Centre Area, several excellent hotels offer amenities and features to ensure a comfortable stay, including Raffles Boston, The Lenox Hotel Boston, Residence Inn by Marriott Boston Back Bay/Fenway, and Four Seasons Hotel One Dalton Street, Boston.

Raffles Boston is a 5-star hotel with an outstanding 9.6 rating. This hotel provides connecting rooms, books and games for children, kids' meals, children's bathrobes, complimentary cribs, and onsite babysitting services. Guests frequently praise the attentive staff, nice rooms, and convenient location, with Innovation District just 2.9 km away and Gibson House Museum 0.7 km away.

Another highly-rated option is The Lenox Hotel Boston, a 4.5-star hotel with a 9.6 rating. It offers complimentary cribs, kids' meals in the restaurant, onsite babysitting, connecting rooms, and rollaway extra beds. The hotel also features a child-friendly window design for added peace of mind. Customers appreciate the friendly and helpful staff, excellent location, and clean rooms.

The 3-star Residence Inn by Marriott Boston Back Bay/Fenway, rated 9.2, is a great choice for families. It provides complimentary rollaway extra beds and cribs, sofa beds, connecting rooms, and a pool. It's conveniently located near The Fens, just 0.3 km away, and the Isabella Stewart Gardner Museum, 0.8 km away. Guests frequently mention the clean rooms, friendly staff, and great breakfast.

The 5-star Four Seasons Hotel One Dalton Street, Boston, with a 9.6 rating, is another excellent family-friendly option. It offers complimentary rollaway extra beds and cribs, connecting rooms, a pool, sofa beds, and kids' meals in the restaurant. The hotel is praised for its exceptional staff, great location, and clean rooms. It is 1.5 km from The Fens and 1.3 km from Gibson House Museum.
What are the best 5-star hotels in Medical Center Area?
For exceptional 5-star accommodation in the Medical Centre Area, consider the Raffles Boston, Mandarin Oriental, Boston, and the Four Seasons Hotel One Dalton Street, Boston.

The 5-star Raffles Boston, with an outstanding 9.6 rating, offers luxurious features such as deep soaking bathtubs, rainfall showerheads, and designer toiletries. Guests frequently praise the attentive staff and great rooms. The hotel also provides 24-hour room service and valet parking, and is conveniently located near 200 Clarendon Street, just 0.1 km away.

Another excellent choice is the 5-star Mandarin Oriental, Boston, rated 9.4. This hotel boasts Frette Italian sheets and premium bedding for a truly comfortable stay, along with 24-hour room service and valet parking. Guests consistently praise the amazing staff and excellent location, with 200 Clarendon Street just 0.6 km away.

The 5-star Four Seasons Hotel One Dalton Street, Boston, also with a 9.6 rating, offers a refined experience. It features deep soaking bathtubs, designer toiletries, and premium bedding. The hotel also provides 24-hour room service and valet parking. Travellers regularly highlight the exceptional staff, great facilities, and clean rooms. It is also conveniently located near 200 Clarendon Street, 0.9 km away.
What are the best spa hotels in Medical Center Area?
For an exceptional spa experience in the Medical Centre Area, consider the Mandarin Oriental, Boston, Raffles Boston, Four Seasons Hotel One Dalton Street, Boston, or the Iris Hotel Boston.

The 5-star Mandarin Oriental, Boston, with an impressive 9.4 rating, offers an extensive spa experience including deep tissue, hot stone, and Swedish massages, hydrotherapy treatments, and a steam room. Guests consistently praise the amazing and always willing to help staff, the excellent location, and the perfect, clean rooms. It is conveniently located near 200 Clarendon Street and the Christian Science Plaza.

Another outstanding option is the 5-star Raffles Boston, boasting an excellent 9.6 rating. This hotel provides a full-service spa with a hot tub, steam room, and dedicated treatment rooms for massages and body treatments. Reviewers frequently highlight the attentive staff, nice rooms, and convenient location, being very close to 200 Clarendon Street and Gallery Naga.

The 5-star Four Seasons Hotel One Dalton Street, Boston, also with a 9.6 rating, features a full-service spa offering body wraps, scrubs, manicures, pedicures, and a steam room. Guests consistently praise the exceptional staff, great location, and clean rooms. It's ideally situated near the Christian Science Plaza and Prudential Tower.

For a highly-rated 4-star option, the Iris Hotel Boston, with a 9.4 rating, provides a range of spa services including deep tissue and hot stone massages, aromatherapy, and facial treatments. Travellers appreciate the friendly and helpful staff, comfortable rooms, and excellent location, being close to the John Fitzgerald Kennedy National Historic Site.
What are the top boutique hotels in Medical Center Area?
For a top boutique hotel in the Medical Centre Area, The Westin Copley Place, Boston, a Marriott Hotel is an excellent choice.

This 4-star hotel, with a 9.2 rating, is known for its Art Deco design and offers premium bedding for a comfortable stay. Guests often highlight the convenient location and the friendly, helpful staff. The hotel provides excellent fitness facilities, including a 24-hour fitness centre and on-site yoga and fitness classes. It is also very close to 200 Clarendon Street, just 0.2 km away, and the Prudential Tower, 0.4 km away.
What are the most romantic hotels in Medical Center Area for couples?
For a romantic stay in the Medical Centre Area, several highly-rated hotels offer exceptional experiences for couples, including The Eliot Hotel, Four Seasons Hotel One Dalton Street, Boston, Raffles Boston, and Iris Hotel Boston.

The 4-star Eliot Hotel, with a superb 9.6 rating, is a wonderful choice for couples. It features elegant suites, premium bedding, and designer toiletries. Guests frequently praise the excellent staff and spacious, clean rooms. Dining options for couples are available, and the hotel provides valet parking. It is also conveniently located near the Prudential Tower, just 0.5 km away, and the Christian Science Plaza, 0.6 km away.

Another outstanding option is the 5-star Four Seasons Hotel One Dalton Street, Boston, which also boasts a 9.6 rating. This hotel is situated in a shopping district and offers luxurious amenities such as deep soaking bathtubs, designer toiletries, and 24-hour room service. Couples can enjoy treatment rooms, and guests consistently praise the exceptional staff and facilities. The hotel is very close to the Prudential Tower, only 0.2 km away, and the Christian Science Plaza, 0.3 km away.

The 5-star Raffles Boston, rated 9.6, provides a truly luxurious and romantic experience. It features deep soaking bathtubs, rainfall showerheads, designer toiletries, and fireplaces. Couples can indulge in spa amenities like a hot tub, sauna, and couples treatment rooms. Guests frequently highlight the attentive staff and convenient location. It is just 0.1 km from 200 Clarendon Street and 0.6 km from the Prudential Tower.

Finally, the 4-star Iris Hotel Boston, with a 9.4 rating, is another excellent choice for couples. This hotel offers premium bedding, Frette Italian sheets, champagne service, and private indoor hot tubs for a truly intimate experience. Guests appreciate the friendly and helpful staff, comfortable rooms, and excellent location. It is located 0.7 km from the John Fitzgerald Kennedy National Historic Site.
When is the best time to go to Medical Center Area?
The best time to visit the Medical Center Area is during the late spring (May to June) or early autumn (September to October).

These periods offer pleasant weather, with moderate temperatures and less humidity than the peak summer months. You'll find it comfortable for walking around and exploring the area's amenities. Additionally, these shoulder seasons generally mean fewer crowds compared to the busiest summer travel period, leading to a more relaxed experience.

For those visiting for medical appointments, these months also generally provide a calmer environment around the hospitals and clinics.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Medical Center Area hotel for you.
How much is the nightly rate at a Medical Center Area hotel?
Hotel prices in Medical Center Area often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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