Medical Center Area Vacation Packages

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    Save up to CA $4,200 when you book a flight and hotel together*

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Top Holiday Package Deals in Medical Center Area

Price found within the past 48 hours. Click for updated prices.
Good Hotels Boston

Good Hotels Boston

2 out of 5
South End
Price was CA $1,451, price is now CA $860 per person
CA $860
per person
Aug 20 - Aug 23
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Boston (BOS)
8/10 Very good! (55 reviews)
This was a very clean and well-looked after property, and the staff went out of their way to check everything was in order.

Reviewed on May 23, 2026

Boston Harbor Hotel

Boston Harbor Hotel

5 out of 5
North End
Price was CA $2,267, price is now CA $1,121 per person
CA $1,121
per person
Aug 20 - Aug 23
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Boston (BOS)
9.8/10 Exceptional! (1,001 reviews)
From the moment I checked in with Natalie, our 4 days were superb! Natalie was so friendly and explained the property and amenities (our first time there). Even though I researched the property, and am originally from close to Boston, it was the 4th of July weekend, and there was Sooo much going on. Head concierge Nathan provided lots of tips about the best places to see certain events. So helpful. Our room was beautiful and well appointed. I miss the days of the shower cap, sewing kit, slippers, robes, etc. and they provided all that. The bed was extremely comfortable and the housekeeping staff wonderful. We go to Boston a few times a year and will be looking forward to returning here. Fabulous location!

Reviewed on Jul 8, 2026

Fairmont Copley Plaza, Boston

Fairmont Copley Plaza, Boston

4.5 out of 5
Back Bay
Price was CA $2,326, price is now CA $1,339 per person
CA $1,339
per person
Aug 10 - Aug 16
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Boston (BOS)
9/10 Wonderful! (1,254 reviews)
We loved the Fairmont Copley plaza! It’s a very special experience staying on the Gold Floor. The staff takes care of all of your needs and request. We felt so pampered. We stayed over 4th of July and Gold floor had an exclusive event. One of the best hotels we have ever stayed at, and we travel a lot.

Reviewed on Jul 10, 2026

Mandarin Oriental, Boston

Mandarin Oriental, Boston

5 out of 5
Back Bay
Price was CA $4,250, price is now CA $2,533 per person
CA $2,533
per person
Aug 10 - Aug 16
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Boston (BOS)
9.4/10 Exceptional! (432 reviews)
This goes into one of the top hotels I've ever stayed at. I seriously can't think of a single complaint. They gave us the best view of the Boston fireworks on the top floor, and took care of us every step of the way. They even had a big TV set up in the lobby for the World Cup games. The front desk people were super nice, and Ivan was our favorite server!

Reviewed on Jul 7, 2026

The Langham, Boston

The Langham, Boston

5 out of 5
Downtown Boston
Price was CA $1,714, price is now CA $1,022 per person
CA $1,022
per person
Aug 20 - Aug 23
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Boston (BOS)
9.8/10 Exceptional! (1,005 reviews)

Where to stay in Medical Center Area

Find the best Medical Center Area areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center Area
A nighttime street scene with illuminated trees, a market stall, and historic buildings.

Downtown Boston

4.5/5(197 area reviews)

Densely packed with highrise buildings, this area boasts landmarks like Custom House Tower and is close to Quincy Market, Faneuil Hall, and the Old State House. Find headquarters of major banks, hotels, and investment firms here.

Find hotels in Downtown Boston

Medical Center Area Hotel Deals

Hyatt Regency Boston/Cambridge

Hyatt Regency Boston/Cambridge

4 out of 5
575 Memorial Drive Cambridge MA
The price is CA $214 per night from Aug 9 to Aug 10
CA $214
CA $291 total
Aug 9 - Aug 10
includes taxes & fees
9/10 Wonderful! (2,436 reviews)
"The property was located in a nice quiet area for a city hotel. The view was nice by the water and the balcony was comfortable for outdoors dining. The rooms was not as big as we expected, especially traveling with teens. The room was designed with a lot of wasted space. The room AC unit was not ..."

Reviewed on Jul 10, 2026

Hyatt Regency Boston/Cambridge
Seaport Hotel Boston

Seaport Hotel Boston

4 out of 5
1 Seaport Lane Boston MA
Fully refundableReserve now, pay when you stay
The price is CA $268 per night from Jul 26 to Jul 27
CA $268
CA $360 total
Jul 26 - Jul 27
includes taxes & fees
9.6/10 Exceptional! (4,549 reviews)
"very nice hotel great staff"

Reviewed on Jul 10, 2026

Seaport Hotel Boston
The Revolution Hotel

The Revolution Hotel

3.5 out of 5
40 Berkeley Street Boston MA
Fully refundableReserve now, pay when you stay
The price is CA $226 per night from Aug 2 to Aug 3
CA $226
CA $263 total
Aug 2 - Aug 3
includes taxes & fees
9/10 Wonderful! (2,728 reviews)
"Great hotel. Loved the vibe and room was great!"

Reviewed on Jul 8, 2026

The Revolution Hotel
See all 4,153 properties in Medical Center Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Frequently asked questions

How much does a Medical Center Area vacation package cost?
From as little as CA $860, you can create your own Medical Center Area package the way you want. Simply bundle hotels, flights and car rentals and we'll reward you with discounts.
How do I get a cheap travel package to Medical Center Area?
Bundling your flight and hotel with Expedia won't just save precious time — it'll save you a nice amount too. A Medical Center Area vacation package makes it simple to arrange your ideal trip. With more than 550 airlines across the world to pick from, finding flights that fit your busy schedule will be no sweat. In addition to that, we have over 1,000,000 hotels globally to choose from. Now that's what you call choice. No matter who you are, Expedia puts the world within your reach.
Where should I stay in Medical Center Area?
Visitors come from all over the world to experience Fenway Park and TD Garden in Medical Center Area. Stay within walking distance of these top attractions to make sightseeing easy.
What are the top hotels in Medical Center Area?
If it's comfort and convenience you want, you can't beat The Inn at Longwood Medical. Spend your evenings relaxing here and your days roaming around Medical Center Area's finest sights.
How far in advance should I book my Medical Center Area vacation?
While prices change from time to time, we generally suggest booking your vacation as early as possible. Most international airfares can be compared on Expedia up to 12 months in advance. If you're booking last minute, you might still be in luck. Cheap journeys to Medical Center Area sometimes emerge only weeks before departure.
What does an Expedia Medical Center Area travel package include?
Packages include flights, rental cars and hotels, but you can combine any of them to create your dream Medical Center Area escape. You can also add on fun things like activities and experiences once you've made your booking. You're in control! When you bundle your bookings with Expedia, you'll get access to discounts you won't find elsewhere.
What should I know before booking a Medical Center Area travel package?
You can save big by bundling your hotels, airfares and rental cars. Once you've created your package, you can add on sightseeing tours or experiences. Your next awesome vacation is only a few clicks away.
Can I choose my airline with a Medical Center Area Expedia vacation package?
You certainly can. We offer more than 550 airline partners across the globe, so fly with the carrier that's a good fit for your needs.
If I'm not able to travel, can I cancel my Medical Center Area vacation package?
If your travel plans in Medical Center Area have changed, it's good to know that you can amend or cancel your booking. If you made your booking within the last 24 hours, you may be eligible to receive a refund. If your booking was made more than 24 hours ago, your airline, hotel or car rental company may charge a cancellation fee. For more information, visit our Customer Service Portal.

Stay near popular Medical Center Area attractions

Isabella Stewart Gardner Museum

8.0/10 (1 review)
A world-renowned private collection of art and cultural treasures awaits at this small yet lavish museum.
See properties

Things to do

Boston Hop-On Hop-Off Trolley Tour

Boston Old Town Trolley Hop-on Hop-Off City Tour

CA $73
per adult
90% of travellers recommend
Boston Old Town Trolley Hop-on Hop-Off City Tour
Boston CityPASS: Admission to Top 4 Boston Attractions

Boston CityPASS®: Admission to Top 4 Attractions

CA $119
per adult
92% of travellers recommend
Boston CityPASS®: Admission to Top 4 Attractions
View Boston Observation Deck Admission Tickets

View Boston Observation Deck Admission Tickets

CA $39
per adult
88% of travellers recommend
View Boston Observation Deck Admission Tickets
See all activities in Boston
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.