Photo by Catherine Edejer-McCormick

Find Spa Hotels in Downtown South San Francisco, San Francisco from CA $172

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Check availability on Downtown South San Francisco Spa Hotels

Tonight
Jul 21 - Jul 22
Tomorrow
Jul 22 - Jul 23
This weekend
Jul 25 - Jul 27
Next weekend
Aug 1 - Aug 3

Top Downtown South San Francisco Spa Hotels

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Exterior

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3.0 star property
8.0 out of 10, Very good, (2022)
"I liked that the hotel was located near Denny’s restaurant as I did not have a car and was able to walk to get something to eat for supper! There were 2 buildings for this property and my room was in the second building so I had to walk back and forth to the buildings I loved the breakfast that was offered and the outdoor heated pool was great!"
Marjorie
The price is CA $172
CA $201 total
includes taxes & fees
Jul 28 - Jul 29
La Quinta Inn & Suites by Wyndham San Francisco Airport N
NEWLY FURNISHED! RECENTLY RENOVATED! CUTE SPACE! CLOSE TO SFO!
Fridge, microwave, oven, stovetop

NEWLY FURNISHED! RECENTLY RENOVATED! CUTE SPACE! CLOSE TO SFO!

9.2 out of 10, Wonderful, (7)
"I wanted some place to unwind after a long road trip and this South San Francisco gem was just perfect. With all of the comforts of home, I was able to prepare meals, sleep as I pleased and enjoy solitude and silence"
John B.
The price is CA $183
CA $431 total
includes taxes & fees
Jul 25 - Jul 26
NEWLY FURNISHED! RECENTLY RENOVATED! CUTE SPACE! CLOSE TO SFO!
Beautiful 1 Bedroom Apartment minutes to SFO in Victorian Home (Can sleep 4)
Exterior

Beautiful 1 Bedroom Apartment minutes to SFO in Victorian Home (Can sleep 4)

9.4 out of 10, Exceptional, (135)
"Lovely snacks and welcome card on the dining table. Comfortable electric fireplace and nice bed to sleep in."
Adit P.
Beautiful 1 Bedroom Apartment minutes to SFO in Victorian Home (Can sleep 4)
Glamorous South San Francisco Home
Living area

Glamorous South San Francisco Home

10.0 out of 10, Exceptional, (2)
"My family was out of town visiting and loved their stay here at this property. It was very clean and spacious. The master bathroom in particular was amazing! It was like we had our own personal
spa
in the house. The location was also good - close access to San Francisco. Hoa was a great host and was very responsive when we had any questions or issues. Would highly recommend!!"
Monica C.
Glamorous South San Francisco Home
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Downtown South San Francisco Hotel Reviews

Hotel Spero, Vignette Collection by IHG

Hotel Spero, Vignette Collection by IHG

10/10 Excellent
"Everything was pretty good service except we got a room next to the elevator and that was pretty noisy. We would have changed but there was no more rooms available to change too. They should tell you that our room was next to the elevator."
Albert 1-night trip
Posted 12 hours ago
Hotel Spero, Vignette Collection by IHG

Frequently asked questions

Looking for a spa hotel in Downtown South San Francisco?
Forget the stress of everyday life and book yourself a hotel with a spa. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Downtown South San Francisco?
Inn By The SFO is a top spa hotel with 23 rooms, free WiFi, and coffee/tea in the lobby.
How many spa hotels will I find in Downtown South San Francisco?
Among Expedia's 42 accommodation options in Downtown South San Francisco, there are 2 spa hotels.
What's there to see and do in Downtown South San Francisco?
Experience all that Downtown South San Francisco has to offer when you visit San Francisco Bay, Chase Center, and Oracle Park. If you have a little extra time during your trip, you might want to check out Pier 39 and Alcatraz Island.
What is a Downtown South San Francisco spa hotel?
Spa hotels in Downtown South San Francisco provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.