Title: Book The Best Hotels in Byron, MN for 2026 from CA $82 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Byron](https://expedia.ca/Byron-Vacation-Rentals.d553248623858895563.Travel-Guide-VacationRentals)[Byron Car Rentals](https://expedia.ca/Car-Rentals-In-Byron.d553248623858895563.Car-Rental-Guide)[Byron Vacation Packages](https://expedia.ca/Byron.d553248623858895563.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Byron, MN from CA $82 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Byron Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America®ionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2025-12-18&d1=2025-12-18&endDate=2025-12-20&d2=2025-12-20&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America®ionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2025-12-18&d1=2025-12-18&endDate=2025-12-20&d2=2025-12-20&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America®ionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2025-12-18&d1=2025-12-18&endDate=2025-12-20&d2=2025-12-20&amenities=HOT_TUB) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America®ionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2025-12-18&d1=2025-12-18&endDate=2025-12-20&d2=2025-12-20&amenities=PETS) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America®ionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2025-12-18&d1=2025-12-18&endDate=2025-12-20&d2=2025-12-20&lodging=APARTMENT) Condo [](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America®ionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2025-12-18&d1=2025-12-18&endDate=2025-12-20&d2=2025-12-20&lodging=CONDO) ## Check prices for these dates Tonight [Dec 4 - Dec 5](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2025-12-04&endDate=2025-12-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 5 - Dec 6](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2025-12-05&endDate=2025-12-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 384 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/f91e65d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/86c17899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/ecda08e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Grand Hotel Downtown Rochester 8.4/10 Very good (1789) "Great hotel close to everything convenient location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marta CA $155 CA $179 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/37e2c033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/fdcb0eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/055a808d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Mayo Clinic Area Rochester 9.0/10 Wonderful (887) "Good breakfast..shuttle service is excellent..super nice staff.." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DALE K CA $88 CA $101 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) ![Serves lunch, dinner, and happy hour](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/3b0f1e42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/493f76e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/3bd995bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Rochester Near Mayo Clinic Rochester 8.2/10 Very good (1126) "Was great for a stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) eric CA $102 CA $117 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/daff149b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's pool](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/f69df08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/12906a03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S Rochester 7.2/10 Good (1029) "Great value for the price. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth Anne CA $95 CA $109 total includes taxes & fees Dec 5 - Dec 6 [](https://www.expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/bac0b2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/3613a59b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/b1805314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG Kutzky Park 9.4/10 Exceptional (950) "Hotel was spotless, excellent staff and the breakfast was excellent. Late night eats at the restaurant and the food served was fantastic." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carmino CA $122 CA $143 total includes taxes & fees Dec 26 - Dec 27 [](https://www.expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/8b35b717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/10494388.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/7b237c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aspen Suites Rochester 9.0/10 Wonderful (685) "I always stay at this hotel , love it clean comfortable rooms, they gave us vouchers for 4 free meals for Thanksgiving dinner" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cindy [](https://www.expedia.ca/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/42f521a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/f4426c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/bd0b7bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG Downtown Rochester 8.8/10 Excellent (881) "Great room and stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trevor CA $96 CA $111 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/1b6617d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/7f2ecd4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/0c1d91fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/fdc1ffe6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic Rochester 7.8/10 Good (1002) "Rooms where very neet and tidy , breakfast was decent and the price was quite a value point " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard CA $89 CA $102 total includes taxes & fees Dec 12 - Dec 13 [](https://www.expedia.ca/Rochester-Hotels-Microtel-Inn-Suites-By-Wyndham-Rochester-North-Mayo-Clinic.h116574.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/c3584a83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/63ec118a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/937e22b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/569ab236.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites Rochester South Mayo Clinic Rochester 8.4/10 Very good (1001) "Clean room, fun staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $117 CA $135 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h455558.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/39da8a7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/222c4dee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/bdf57892.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/02cd0879.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys Kutzky Park 8.6/10 Excellent (928) "This is a convenient place to stay when visiting Mayo." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Faith CA $124 CA $142 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/bde7ad17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/7b075080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, desk](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/24e0abff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/d3281bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Rochester Mayo Clinic Area South Rochester 9.6/10 Exceptional (241) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steve CA $166 CA $191 total includes taxes & fees Dec 12 - Dec 13 [](https://www.expedia.ca/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area-South.h90610605.Hotel-Information) ![Coffee service](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/5f8bd693.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/84709368.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/c5b39a44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/03c26c35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MainStay Suites Rochester South Mayo Clinic Rochester 7.0/10 Good (88) "Staff is friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Merry CA $77 CA $88 total includes taxes & fees Dec 6 - Dec 7 [](https://www.expedia.ca/Rochester-Hotels-Extended-Stay-America-Suites-Rochester-South.h846574.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/6da96ba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/f6a03fe3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/dd4123a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/bab1f0e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Rochester Mayo Clinic Area Rochester 7.8/10 Good (1004) "Great Stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aweng CA $71 CA $82 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Rochester-Hotels-Super-8-By-Wyndham-Rochester-Mayo-Clinic-Area.h25164.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/fce6cfb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/34563649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/c7dc0b32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Rochester South Rochester 9.4/10 Exceptional (297) "The rooms are very nice and the staff is very friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roberta CA $96 CA $111 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/92dc90b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/c5c5f3cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/25e32575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/fca8e68c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aspen Select Rochester 8.4/10 Very good (1000) "Safe parking very clean and breakfast had options for anyone" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cindy [](https://www.expedia.ca/Rochester-Hotels-Aspen-Select.h12245240.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/76e6edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/5419eb23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/fe70c541.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/19467991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Rochester Mayo Clinic Area Rochester 7.2/10 Good (716) "Spotless clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brit CA $83 CA $96 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Rochester-Hotels-Baymont-By-Wyndham-Rochester-Mayo-Clinic-Area.h459763.Hotel-Information) ![2 indoor pools](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/821fc05d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/f8e4d672.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/f78e7c09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Med City Inn & Suites - Mayo Clinic Area Kutzky Park 7.8/10 Good (1000) "Great staff, room was clean and location was great for our needs." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tim CA $101 CA $116 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/50c22b07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Billiards](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/6b44b2f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/36a69ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/4d028fa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Berkman Folwell 9.6/10 Exceptional (367) "Perfect location for visit to hospital. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon CA $220 CA $255 total includes taxes & fees Dec 6 - Dec 7 [](https://www.expedia.ca/Rochester-Hotels-Berkman-Hotel.h46291477.Hotel-Information) ![Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room)](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room)](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/ec5f8616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3837h2560x3y0-014e984a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room)](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/d609b8e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's Rochester 8.2/10 Very good (781) "Great place to stay. Freindly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) joel CA $131 CA $151 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/b1555778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/1213b471.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/f4c0d6e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/86063f91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Rochester Mayo Clinic Area Downtown Rochester 9.6/10 Exceptional (540) "Had a great stay. Room was very clean and staff was very courteous. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bonita CA $239 CA $275 total includes taxes & fees Dec 12 - Dec 13 [](https://www.expedia.ca/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-18&endDate=2025-12-19®ionId=553248623858895563&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FByron-Hotels.d553248623858895563.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FByron-Hotels.d553248623858895563.Travel-Guide-Hotels) ### Stay near popular Byron attractions [](https://expedia.ca/Oxbow-Park-Hotels.0-l6308341-0.Travel-Guide-Filter-Hotels) #### Oxbow Park Explore the great outdoors at Oxbow Park, a lovely green space in Byron. Check out the top-notch restaurants or charming coffeehouses in this walkable area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6308341) ## More cheap stays in Byron ![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Rochester-South 1755 S Broadway Rochester MN CA $115 CA $132 total Dec 26 - Dec 27 includes taxes & fees 9/10 Wonderful! (1,014 reviews) [](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Brentwood Inn & Suites 123 Fourth Ave. NW Rochester MN CA $157 CA $181 total Dec 5 - Dec 6 includes taxes & fees 8.6/10 Excellent! (1,002 reviews) [](https://expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/821fc05d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Med City Inn & Suites - Mayo Clinic Area 435 16th Ave Nw Rochester MN CA $101 CA $116 total Dec 7 - Dec 8 includes taxes & fees 7.8/10 Good! (1,022 reviews) [](https://expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Econo Lodge Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Econo Lodge Mayo Clinic Area 1850 S Broadway Rochester MN CA $88 CA $101 total Dec 19 - Dec 20 includes taxes & fees 9/10 Wonderful! (885 reviews) [](https://expedia.ca/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) ![Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/1b6617d7_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic 4210 Highway 52 North Rochester MN CA $89 CA $102 total Dec 12 - Dec 13 includes taxes & fees 7.8/10 Good! (1,011 reviews) [](https://expedia.ca/Rochester-Hotels-Microtel-Inn-Suites-By-Wyndham-Rochester-North-Mayo-Clinic.h116574.Hotel-Information) ![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's 1517 16th St Sw Rochester MN CA $131 CA $151 total Dec 11 - Dec 12 includes taxes & fees 8.2/10 Very Good! (781 reviews) [](https://expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ## Hotels in Byron with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 2 properties [](https://expedia.ca/4Star-Byron-Hotels.s40-0-d553248623858895563.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 42 properties [](https://expedia.ca/3Star-Byron-Hotels.s30-0-d553248623858895563.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 52 properties [](https://expedia.ca/2Star-Byron-Hotels.s20-0-d553248623858895563.Travel-Guide-Filter-Hotels) ## Recent reviews of Byron hotels ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 5/5 Excellent "Nice comfortable. Renovated rooms. " A verified traveller stayed at Kahler Grand Hotel Posted 2 days ago [](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Spark by Hilton Rochester South](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg) ### Spark by Hilton Rochester South 5/5 Excellent "Amazing staff!" A verified traveller stayed at Spark by Hilton Rochester South Posted 2 days ago [](https://expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg) ### Brentwood Inn & Suites 5/5 Excellent "Very clean and comfortable. Connected to Mayo Clinic by subway was very convenient. Will stay here on future visits. " A verified traveller from Cherry valley stayed at Brentwood Inn & Suites Posted 2 days ago [](https://expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![Kahler Inn and Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 5/5 Excellent "Super helpful staff! Clean, comfortable room and great location for appts at the Mayo Clinic." A verified traveller stayed at Kahler Inn and Suites - Mayo Clinic Area Posted 2 days ago [](https://expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![Aspen Select](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/92dc90b5_y.jpg) ### Aspen Select 5/5 Excellent "Great location Nice staff Well maintained" A verified traveller stayed at Aspen Select Posted 3 days ago [](https://expedia.ca/Rochester-Hotels-Aspen-Select.h12245240.Hotel-Information) ![Hilton Garden Inn Rochester Downtown, MN](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/67ee8968_y.jpg) ### Hilton Garden Inn Rochester Downtown, MN 5/5 Excellent "The staff were all very courteous and helpful. Rooms very clean. Would definitely stay at the Hilton Garden Inn in the future." A verified traveller stayed at Hilton Garden Inn Rochester Downtown, MN Posted 3 days ago [](https://expedia.ca/Rochester-Hotels-Hilton-Garden-Inn-Rochester-Downtown.h214679.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/821fc05d_y.jpg) ### Med City Inn & Suites - Mayo Clinic Area 5/5 Excellent "Pleasant stay, great location" A verified traveller stayed at Med City Inn & Suites - Mayo Clinic Area Posted 3 days ago [](https://expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Hotel Indigo Rochester – Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG 5/5 Excellent "Room and location" A verified traveller stayed at Hotel Indigo Rochester – Mayo Clinic Area by IHG Posted 3 days ago [](https://expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg) ### Hampton Inn Rochester-South 5/5 Excellent "We had a wonderful stay!" A verified traveller stayed at Hampton Inn Rochester-South Posted 4 days ago [](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ## Frequently asked questions ### When is the best time to go to Byron? > During the peak season from December to January, Byron Bay buzzes with vibrant tourist activity. The festive spirit is palpable as visitors flock to the area, drawn by its stunning beaches, world-class dining, and lively festivals. It's a fantastic time to immerse yourself in the local culture, with events showcasing music, art, and culinary delights that make Byron Bay a unique destination. > > > For those who enjoy a more tranquil experience, consider visiting in September or October. This is when the crowds begin to thin out, yet the climate remains pleasantly warm, with temperatures typically around 23 to 27°C. This shoulder season allows for a more relaxed exploration of the area's natural beauty and attractions, all while still enjoying good weather for outdoor pursuits like hiking in the nearby national parks. > > > Families and couples alike will find plenty of opportunities to create lasting memories in Byron Bay, from dolphin watching to indulging in relaxing spa treatments. The laid-back vibe and emphasis on quality experiences ensure that every visitor can find something to suit their tastes. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Byron hotel booking with Expedia? ### How much is the nightly rate at a Byron hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - More ways to book - [4 Star Hotels in Northwest ](https://www.expedia.ca/4Star-Northwest-Rochester-Hotels.s40-n900102874825277440-0.Travel-Guide-Filter-Hotels) - [Hotels near Apache Mall ](https://www.expedia.ca/Apache-Mall-Hotels.0-l6188936-0.Travel-Guide-Filter-Hotels) - [Apartments in Cascade Township ](https://www.expedia.ca/Cascade-Township-Apartments.d553248635976432144-aaApartments.Travel-Guide-Accommodation) - [Vacation Homes in Cascade Township ](https://www.expedia.ca/Cascade-Township-Private-Vacation-Homes.d553248635976432144-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Claremont Hotels ](https://www.expedia.ca/Claremont-Hotels.d553248623504756947.Travel-Guide-Hotels) - 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