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Our top choices for Byron hotels

Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
2.0 star property
Rochester
8.8 out of 10, Excellent, (1,003 reviews)
"For the price of the hotel was extremely well maintained housekeeping, staffless the herb, all on all of your nice newer property"
United States
David
The price is CA $111
CA $128 total
includes taxes & fees
Jun 21 - Jun 22
Comfort Inn & Suites Rochester South Mayo Clinic

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1,003 reviews)
"Great experience, would definitely stay again!!"
United States
Mike
The price is CA $128
CA $148 total
includes taxes & fees
Jul 4 - Jul 5
Hampton Inn Rochester-South

Americas Best Value Inn & Suites Spring Valley

Americas Best Value Inn & Suites Spring Valley
2.0 star property
Spring Valley
8.2 out of 10, Very good, (450 reviews)
"It was a very clean and well maintained hotel"
United States
Tade
The price is CA $124
CA $137 total
includes taxes & fees
Jul 1 - Jul 2
Americas Best Value Inn & Suites Spring Valley

Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
Rochester
9.4 out of 10, Exceptional, (490 reviews)
"Comfortable beds, and friendly staff."
United States
Desyre
The price is CA $121
CA $139 total
includes taxes & fees
Jun 14 - Jun 15
Spark by Hilton Rochester South

America's Stay Inn Stewartville

America's Stay Inn Stewartville
2.5 star property
Stewartville
8.0 out of 10, Very good, (449 reviews)
"Very nice clean rooms with plenty of parking. Will stay here again when traveling in the future."
United States
Debbie
The price is CA $88
CA $94 total
includes taxes & fees
Jun 8 - Jun 9
America's Stay Inn Stewartville

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.4 out of 10, Good, (1,062 reviews)
"we enjoyed our stay"
United States
Richard
The price is CA $102
CA $117 total
includes taxes & fees
Jun 21 - Jun 22
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester
9.0 out of 10, Wonderful, (1,011 reviews)
"Great location, a few minutes walk to the civic center. Plenty of good food options around the area. The staff is friendly and helpful, rooms and commons are clean, loved the breakfast menu."
United States
Ayesha
The price is CA $236
CA $271 total
includes taxes & fees
Jun 7 - Jun 8
Hyatt House Rochester/Mayo Clinic Area

Aspen Suites

Aspen Suites
3.0 star property
Rochester
9.0 out of 10, Wonderful, (850 reviews)
"Great place to stay near downtown!! Breakfast was good and the hotel room was very clean!"
United States
Rhianon
The price is CA $208
CA $251 total
includes taxes & fees
Jun 7 - Jun 8
Aspen Suites

Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1,006 reviews)
"Room was clean, nice shower, and the breakfast was tasty with good variety."
United States
Nicole
The price is CA $139
CA $160 total
includes taxes & fees
Jun 21 - Jun 22
Holiday Inn Express Rochester South - Mayo Area by IHG

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
3.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (710 reviews)
"Clean comfortable beds and great breakfast options"
United States
Toni
The price is CA $149
CA $172 total
includes taxes & fees
Jul 3 - Jul 4
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
Historic Southwest
8.6 out of 10, Excellent, (1,014 reviews)
"Very affordable we were visiting family overall stay was prefect"
United States
James
The price is CA $159
CA $183 total
includes taxes & fees
Jun 12 - Jun 13
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
2.5 star property
Rochester
9.2 out of 10, Wonderful, (1,008 reviews)
"Great hotel. Convenient location, clean, friendly staff."
United States
Yuliya
The price is CA $147
CA $170 total
includes taxes & fees
Jul 5 - Jul 6
Hampton Inn & Suites Rochester-North

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
Rochester
8.2 out of 10, Very good, (934 reviews)
"Great place"
United States
Shayn
The price is CA $110
CA $127 total
includes taxes & fees
Jun 14 - Jun 15
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.0 out of 10, Very good, (1,345 reviews)
"Good breakfast, good value, and a restaurant on site."
United States
Timothy
The price is CA $109
CA $125 total
includes taxes & fees
Jun 14 - Jun 15
AmericInn by Wyndham Rochester Near Mayo Clinic

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester
9.6 out of 10, Exceptional, (605 reviews)
"Nice pool, sauna, and steam room. Staff were incredibly friendly. Food was good. Room was clean."
United States
Heather
The price is CA $239
CA $275 total
includes taxes & fees
Jul 3 - Jul 4
Hilton Rochester Mayo Clinic Area

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (1,009 reviews)
"As always it was a wonderful stay!"
United States
Misty
The price is CA $156
CA $180 total
includes taxes & fees
Jun 20 - Jun 21
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
3.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (484 reviews)
"Great stay!"
United States
Kristina
The price is CA $170
CA $199 total
includes taxes & fees
Jun 14 - Jun 15
Staybridge Suites Rochester - Mayo Clinic Area by IHG

Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
Rochester
9.0 out of 10, Wonderful, (992 reviews)
"It was a clean, comfortable hotel with a friendly and helpful staff."
United States
Andrea
The price is CA $102
CA $118 total
includes taxes & fees
Jul 5 - Jul 6
Econo Lodge Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Kutzky Park
9.6 out of 10, Exceptional, (534 reviews)
"Great place to stay"
United States
Brian
The price is CA $177
CA $204 total
includes taxes & fees
Jun 12 - Jun 13
TownePlace Suites by Marriott Rochester Mayo Clinic Area

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
2.0 star property
Rochester
8.0 out of 10, Very good, (1,007 reviews)
"Our room was very clean. The hotel itself only so-so. The continental breakfast was quite nice!"
United States
Johanna
The price is CA $97
CA $112 total
includes taxes & fees
Jun 21 - Jun 22
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is the best area to stay in Byron?
The best area to stay in Byron is near the US-14 corridor, particularly around the Byron Business Park, as this offers the most convenient access and amenities.

This area is the commercial hub of Byron. It's characterised by modern developments and easy access to major roads, making it simple to navigate. You'll find a selection of dining options and local services here, all designed for convenience.

For business travellers, staying in this area is ideal due to its proximity to local businesses and the main arterial routes. The hotels here often cater to this audience with facilities like meeting rooms and high-speed internet, ensuring a productive stay.

Families visiting Byron will also find this area practical. The accessibility to US-14 means less time travelling and more time enjoying local activities or exploring nearby Rochester.
When is the best time to go to Byron?
The best time to visit Byron, Minnesota, is during the late spring, summer, and early autumn months, from May to October, when the weather is most pleasant for outdoor activities.

May and June offer mild temperatures, generally ranging from 10°C to 25°C, making it pleasant for exploring the local parks and trails. The greenery is lush, and it's a good time for those who enjoy hiking or cycling without the peak summer heat.

July and August are the warmest months, with average temperatures usually between 20°C and 30°C. This is ideal for enjoying the nearby lakes and rivers, such as those found in Whitewater State Park, which is a short drive away. Families often find these months great for a holiday due to the warm weather and school breaks.

September and October bring cooler temperatures, typically between 5°C and 20°C, and the stunning autumn foliage. This period is excellent for scenic drives and enjoying the vibrant colours of the changing leaves. It's a wonderful time for couples seeking a peaceful getaway and picturesque views.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Byron.
How can I save on a Byron hotel booking with Expedia?
Members always get our best prices. Find our best Byron hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Byron hotel?
Prices for hotels in Byron often vary, but you can find a great deal from CA $87 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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