Title: Book The Best Hotels in Byron, MN for 2025 from CA $90 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Byron](https://expedia.ca/Byron-Vacation-Rentals.d553248623858895563.Travel-Guide-VacationRentals)[Byron Car Rentals](https://expedia.ca/Car-Rentals-In-Byron.d553248623858895563.Car-Rental-Guide)[Byron Vacation Packages](https://expedia.ca/Byron.d553248623858895563.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Byron, MN from CA $90 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Byron Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America®ionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2025-10-19&d1=2025-10-19&endDate=2025-10-21&d2=2025-10-21&amenities=PETS) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America®ionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2025-10-19&d1=2025-10-19&endDate=2025-10-21&d2=2025-10-21&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America®ionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2025-10-19&d1=2025-10-19&endDate=2025-10-21&d2=2025-10-21&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America®ionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2025-10-19&d1=2025-10-19&endDate=2025-10-21&d2=2025-10-21&amenities=HOT_TUB) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America®ionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2025-10-19&d1=2025-10-19&endDate=2025-10-21&d2=2025-10-21&lodging=APARTMENT) ## Check prices for these dates Tonight [Oct 5 - Oct 6](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2025-10-05&endDate=2025-10-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 6 - Oct 7](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2025-10-06&endDate=2025-10-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 380 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/f91e65d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/86c17899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/ecda08e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Grand Hotel Downtown Rochester 8.2/10 Very good (1640) "Great location, beautiful hotel!" CA $169 CA $195 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/231bcb83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/fdcb0eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/37e2c033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Mayo Clinic Area Rochester 9.0/10 Wonderful (821) "All staff was friendly and the room and surroundings were clean." CA $96 CA $110 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) ![Serves lunch, dinner, and happy hour](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/3b0f1e42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/493f76e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/3bd995bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Rochester Near Mayo Clinic Rochester 8.2/10 Very good (1058) "Good place to stay " CA $103 CA $119 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/dd818bd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/daff149b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's pool](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/f69df08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S Rochester 7.2/10 Good (1002) "well kept great staff " CA $100 CA $116 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/eabb718a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/bac0b2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/b1805314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG Kutzky Park 9.4/10 Exceptional (910) "Always stay here for my mayo visits " CA $166 CA $194 total includes taxes & fees Oct 11 - Oct 12 [](https://www.expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/8b35b717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/13abbe0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/10494388.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aspen Suites Rochester 9.0/10 Wonderful (659) "Staff were very friendly, property was nice and clean." CA $185 CA $235 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/1b6617d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/7f2ecd4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/0c1d91fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/fdc1ffe6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic Rochester 7.8/10 Good (1005) "Was a nice hotel for the money. Breakfast was great. " CA $91 CA $105 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Rochester-Hotels-Microtel-Inn-Suites-By-Wyndham-Rochester-North-Mayo-Clinic.h116574.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/f4426c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/42f521a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/bd0b7bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG Downtown Rochester 8.8/10 Excellent (835) "Very convenient to Mayo clinic and good restaurants. " CA $112 CA $129 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/c7dc0b32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/fce6cfb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/00ce891c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Rochester South Rochester 9.4/10 Exceptional (193) "Check in was easy and staff was extremely helpful! We'll definitely stay here again. " CA $102 CA $117 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Coffee service](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/5f8bd693.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/03c26c35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/c5b39a44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/84709368.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MainStay Suites Rochester South Mayo Clinic Rochester 7.2/10 Good (79) "Nice hotel. Friendly staff and quiet. " CA $79 CA $90 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Rochester-Hotels-Extended-Stay-America-Suites-Rochester-South.h846574.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/50c22b07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Billiards](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/6b44b2f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/4d028fa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/5776b64a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Berkman Folwell 9.6/10 Exceptional (347) "Perfect place to stay, very clean and easy access. " CA $127 CA $148 total includes taxes & fees Oct 18 - Oct 19 [](https://www.expedia.ca/Rochester-Hotels-Berkman-Hotel.h46291477.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/92dc90b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/31690353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/fca8e68c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/c5c5f3cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aspen Select Rochester 8.4/10 Very good (1002) "Clean room | Staff was helpful and friendly" CA $131 CA $158 total includes taxes & fees Oct 10 - Oct 11 [](https://www.expedia.ca/Rochester-Hotels-Aspen-Select.h12245240.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/c3584a83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/569ab236.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/937e22b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/63ec118a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites Rochester South Mayo Clinic Rochester 8.4/10 Very good (1002) "A good place to stay." CA $119 CA $137 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h455558.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/76e6edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/5419eb23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/19467991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/fe70c541.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Rochester Mayo Clinic Area Rochester 7.0/10 Good (693) "Great place to stay close to places needed" CA $85 CA $98 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Rochester-Hotels-Baymont-By-Wyndham-Rochester-Mayo-Clinic-Area.h459763.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/bde7ad17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![16 bedrooms, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/24e0abff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/745c7377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/d3281bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Rochester Mayo Clinic Area South Rochester 9.6/10 Exceptional (223) "Great place" CA $172 CA $198 total includes taxes & fees Oct 17 - Oct 18 [](https://www.expedia.ca/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area-South.h90610605.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/39da8a7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/bdf57892.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/02cd0879.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/222c4dee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys Kutzky Park 8.4/10 Very good (895) "Good hotel in great location Needs updating Staff was very nice Pool and hot tub are nice Nice patio area Room was comfy Good stay for the price " CA $134 CA $154 total includes taxes & fees Oct 24 - Oct 25 [](https://www.expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/f8e4d672.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 indoor pools](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/6897f3e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/f78e7c09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Med City Inn & Suites - Mayo Clinic Area Kutzky Park 7.8/10 Good (1001) "Good location " CA $101 CA $116 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room)](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room)](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/d609b8e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room)](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/ec5f8616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2555x4y4-921fa2b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's Rochester 8.2/10 Very good (740) "staff was great no complaints room was phenomenal." CA $131 CA $151 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/6da96ba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/f6a03fe3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/bab1f0e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/dd4123a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Rochester Mayo Clinic Area Rochester 7.8/10 Good (1003) "Comfortable beds and good breakfast newspaper " CA $78 CA $90 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Rochester-Hotels-Super-8-By-Wyndham-Rochester-Mayo-Clinic-Area.h25164.Hotel-Information) ![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/b33056f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/4b144b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/0647340c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/w2998h3997x0y0-693a0036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area Historic Southwest 8.6/10 Excellent (1003) "We stay here every year for the dog show. It's pet friendly and in a great location " CA $172 CA $198 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-20&endDate=2025-10-21®ionId=553248623858895563&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FByron-Hotels.d553248623858895563.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FByron-Hotels.d553248623858895563.Travel-Guide-Hotels) ### Stay near popular Byron attractions [](https://expedia.ca/Oxbow-Park-Hotels.0-l6308341-0.Travel-Guide-Filter-Hotels) #### Oxbow Park Explore the great outdoors at Oxbow Park, a lovely green space in Byron. Check out the charming coffeehouses or top-notch restaurants in this walkable area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6308341) ## More cheap stays in Byron ![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Brentwood Inn & Suites 123 Fourth Ave. NW, Rochester, MN CA $157 CA $181 total Oct 9 - Oct 10 includes taxes & fees 8.6/10 Excellent! (1,003 reviews) [](https://expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's 1517 16th St Sw, Rochester, MN CA $131 CA $151 total Oct 12 - Oct 13 includes taxes & fees 8.2/10 Very Good! (738 reviews) [](https://expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![Super 8 by Wyndham Rochester Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/6da96ba9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Rochester Mayo Clinic Area 106 SE 21st Street, 21st Street And Broadway, Rochester, MN CA $78 CA $90 total Oct 26 - Oct 27 includes taxes & fees 7.6/10 Good! (1,002 reviews) [](https://expedia.ca/Rochester-Hotels-Super-8-By-Wyndham-Rochester-Mayo-Clinic-Area.h25164.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Med City Inn & Suites - Mayo Clinic Area 435 16th Ave Nw, Rochester, MN CA $101 CA $116 total Oct 12 - Oct 13 includes taxes & fees 7.8/10 Good! (1,000 reviews) [](https://expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/1b6617d7_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic 4210 Highway 52 North, Rochester, MN CA $91 CA $105 total Oct 8 - Oct 9 includes taxes & fees 7.8/10 Good! (1,001 reviews) [](https://expedia.ca/Rochester-Hotels-Microtel-Inn-Suites-By-Wyndham-Rochester-North-Mayo-Clinic.h116574.Hotel-Information) ![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Rochester-South 1755 S Broadway, Rochester, MN CA $124 CA $143 total Nov 6 - Nov 7 includes taxes & fees 8.8/10 Excellent! (1,001 reviews) [](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ## Hotels in Byron with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_w.jpg) 4 Star Hotels 2 properties [](https://expedia.ca/4Star-Byron-Hotels.s40-0-d553248623858895563.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_w.jpg) 3 Star Hotels 42 properties [](https://expedia.ca/3Star-Byron-Hotels.s30-0-d553248623858895563.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_w.jpg) 2 Star Hotels 37 properties [](https://expedia.ca/2Star-Byron-Hotels.s20-0-d553248623858895563.Travel-Guide-Filter-Hotels) ## Recent reviews of Byron hotels ![Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/10000/3600/3556/b33056f7_y.jpg) ### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area 5/5 Excellent "Easy walk to Mayo clinic! The outdoor patio was a great place to unwind after long days of appointments at the Mayo clinic." A verified traveller stayed at Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area Posted 2 days ago [](https://expedia.ca/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) ![Spark by Hilton Rochester South](//images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg) ### Spark by Hilton Rochester South 5/5 Excellent "Clean room, great staff!" A verified traveller stayed at Spark by Hilton Rochester South Posted 2 days ago [](https://expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Kahler Inn and Suites - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 5/5 Excellent "Clean and friendly. Very good breakfast " A verified traveller stayed at Kahler Inn and Suites - Mayo Clinic Area Posted 2 days ago [](https://expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](//images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 5/5 Excellent "well kept great staff " A verified traveller stayed at La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S Posted 4 days ago [](https://expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Kahler Grand Hotel](//images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 5/5 Excellent "There’s a lot of street work in progress around the hotel right now; but the inconvenience is manageable. You can’t beat the price and convenience for proximity and accessibility to the Mayo Clinic. " A verified traveller stayed at Kahler Grand Hotel Posted 5 days ago [](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Hampton Inn Rochester-South](//images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg) ### Hampton Inn Rochester-South 5/5 Excellent "Staff was friendly and helpful. Beds were super comfortable. Breakfast was awesome!" A verified traveller stayed at Hampton Inn Rochester-South Posted 5 days ago [](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![EVEN Hotel Rochester - Mayo Clinic Area by IHG](//images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_y.jpg) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG 5/5 Excellent "Always stay here for my mayo visits " A verified traveller stayed at EVEN Hotel Rochester - Mayo Clinic Area by IHG Posted 5 days ago [](https://expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74_y.jpg) ### Med City Inn & Suites - Mayo Clinic Area 5/5 Excellent "This is one of the best hotels I've ever stayed in.b" A verified traveller stayed at Med City Inn & Suites - Mayo Clinic Area Posted 5 days ago [](https://expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Aspen Select](//images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/92dc90b5_y.jpg) ### Aspen Select 5/5 Excellent "Mayo Clinic is across the street." A verified traveller stayed at Aspen Select Posted 6 days ago [](https://expedia.ca/Rochester-Hotels-Aspen-Select.h12245240.Hotel-Information) ## Frequently asked questions ### When is the best time to go to Byron? > The most popular time to visit Byron Bay is during the warm summer months of December to February. With average temperatures ranging from 25 to 30°C, this period is great for beach lovers and adventure seekers alike. The sunny weather creates an friendly space for outdoor activities, whether you're surfing the waves, relaxing on the beach, or exploring the stunning coastal walks. > > > > During the peak season from December to January, Byron Bay buzzes with vibrant tourist activity. The festive spirit is palpable as visitors flock to the area, drawn by its stunning beaches, world-class dining, and lively festivals. It's a fantastic time to immerse yourself in the local culture, with events showcasing music, art, and culinary delights that make Byron Bay a unique destination. > > > > For those who enjoy a more tranquil experience, consider visiting in September or October. This is when the crowds begin to thin out, yet the climate remains pleasantly warm, with temperatures typically around 23 to 27°C. This shoulder season allows for a more relaxed exploration of the area's natural beauty and attractions, all while still enjoying good weather for outdoor pursuits like hiking in the nearby national parks. > > > > Families and couples alike will find plenty of opportunities to create lasting memories in Byron Bay, from dolphin watching to indulging in relaxing spa treatments. The laid-back vibe and emphasis on quality experiences ensure that every visitor can find something to suit their tastes. ### Can I cancel my hotel reservation on Expedia? > You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Byron. ### How can I save on a Byron hotel booking with Expedia? > Members always get our best prices. Find our best Byron hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings. ### How much is the nightly rate at a Byron hotel? > Prices for hotels in Byron often vary, but you can find a great deal from CA $90 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. 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[Stewartville Hotels](https://www.expedia.ca/Stewartville-Hotels.d183438.Travel-Guide-Hotels) - [Hotels near University of Minnesota-Rochester](https://www.expedia.ca/University-Of-Minnesota-Rochester-Hotels.0-l6126918-0.Travel-Guide-Filter-Hotels) - [Wanamingo Hotels](https://www.expedia.ca/Wanamingo-Hotels.d3000349019.Travel-Guide-Hotels) - [Boutique Hotels in Washington](https://www.expedia.ca/Washington-Rochester-Hotels-Boutique-Hotel.0-n900102744399208448-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Zumbrota Hotels](https://www.expedia.ca/Zumbrota-Hotels.d181483.Travel-Guide-Hotels) - [Flights to Rochester](https://www.expedia.ca/Cheap-Flights-To-Rochester.d3041.Travel-Guide-Flights) - [Flights from Anchorage to Southeast Minnesota](https://www.expedia.ca/lp/flights/178230/6233996/anchorage-to-southeast-minnesota) - [Flights from Boston to Southeast Minnesota](https://www.expedia.ca/lp/flights/178239/6233996/boston-to-southeast-minnesota) - [Flights from Las Vegas to Southeast Minnesota](https://www.expedia.ca/lp/flights/178276/6233996/las-vegas-to-southeast-minnesota) - 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