Byron Vacation Rentals

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Vacation Rentals in Byron

The Berkman
3.0 star property
9.6 out of 10, Exceptional, 210 reviews
"Very nice and clean accommodations. Nice place to relax between appointments at Mayo clinic. Energy and environmentally conscious building. Shuttle service was prompt and reliable. Will definitely stay here again. "
The price is CA $217
CA $252 total
includes taxes & fees
May 31 - Jun 1
The Berkman
Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
9.2 out of 10, Wonderful, 136 reviews
"Parking was convenient. We had a 2 bedroom 2 bath suite that was very spacious and clean. Plenty of storage if one was to stay for an extended time. Both Mayo and Civic Center were accessible via the sky way. I'll definitely being tell others about Broadway Plaza."
The price is CA $207
CA $320 total
includes taxes & fees
Jun 1 - Jun 2
Broadway Plaza, Trademark Collection by Wyndham
Valley Cabin
9.6 out of 10, Exceptional, 4 reviews
"I liked that the cabin is fairly isolated. It was a great location to watch and photograph the Perseid meteor shower. The host was very friendly and accommodating. The only thing I did not like is the lack of running water at the cabin. A very minor issue for me as someone who has done a lot of camping. I would definitely consider staying here again some time. "
The price is CA $82
CA $182 total
includes taxes & fees
Jun 5 - Jun 6
Valley Cabin
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RUSTIC CABIN IN THE WOODS, 5 MIN TO ROCHESTER
6.0 out of 10, 2 reviews
"It started out with no contact from host. Took 1/2 hour to get code. Owners appear to be on property. At night could not get door to stay shut, put a chair against it. Traffic from Hwy 63 was very noisy. I was ok about the airport noise as they disclosed it. Only stayed 1 night due to the above issues. Paid for 2 nights but wasn't worth staying."
RUSTIC CABIN IN THE WOODS, 5 MIN TO ROCHESTER
Century Cottage-PERFECT for Mayo & downtown visitors!
10.0 out of 10, Exceptional, 84 reviews
"Nice stay! Super responsive hosts!"
Century Cottage-PERFECT for Mayo & downtown visitors!
"Walden Pond" Adventure Amidst 44 Private Acres
10.0 out of 10, Exceptional, 105 reviews
"The overall property was very pleasant. The surrounding woods were a relaxing setting from visits at Rochester. The cottage was enjoyable and our host was great to work with."
"Walden Pond" Adventure Amidst 44 Private Acres
St. Augustine Mint House GARAGE!!
10.0 out of 10, Exceptional, 51 reviews
"We were in town for appointments at Mayo Clinic, this apartment is close to Mayo, set up as a beautiful, relaxing place to be in between appointments. The kitchen was well stocked and easy to cook in. It was easy to find and very we’ll maintained, I would choose to stay here in the future."
St. Augustine Mint House GARAGE!!
Lost Creek Executive Home on 200 acre horse Ranch w/Trout Stream
9.6 out of 10, Exceptional, 5 reviews
"We had a very nice long weekend here with teenagers. The beds were comfortable and the land was great for exploring! The kids enjoyed the endless pool. The showers had great pressure and the whirlpool was enjoyed by most - by it was a tub, not a hot tub. The kitchen, while manageable, could use some additions including spatulas, scrappers, cookie sheets - some items one might consider a staple. More practicable dinnerware and cups/glasses might be worth providing. We "figured" out how to work...
Lost Creek Executive Home on 200 acre horse Ranch w/Trout Stream
Mayo Discount Offered-Family-Friendly 2 Level-Near Mayo
8.6 out of 10, Excellent, 16 reviews
"Just keep in mind that the property is very old and so are all the appliances and furniture. When I say old, I mean clawfoot bathtub old. It’s not bad- they all seem to work fine- I just wasn’t expecting that based on the pictures. The house is also set up pretty weird and there are a lot of stairs so keep that in mind if you have mobility issues. Other than that, can’t complain. The place is very clean. The renters seem very nice. There was a moment in which the water needed to be temporarily...
Mayo Discount Offered-Family-Friendly 2 Level-Near Mayo
Cozy, modern 2 bedroom with laundry,+ walk to mayo
9.4 out of 10, Exceptional, 6 reviews
"Awesome host’s with great communication. The home is very comfortable, must be okay with stairs. Clean, great beds, open feel with good lighting and windows throughout. Love the front porch. All appliances in working order, stocked kitchen, solid internet. Just shy of a mile walk downtown or too Main Clinic buildings. Close to river walk, felt safe. Good neighborhood. Would definitely recommend"
Cozy, modern 2 bedroom with laundry,+ walk to mayo
Civic Center, River Front, WALK to Mayo Clinic!! GARAGE Parking!
10.0 out of 10, Exceptional, 85 reviews
"This home is a perfect find for anyone staying in Rochester, particularly conducive to Mayo visits. The home is well maintained with great views and an easy walking vicinity to many attractions."
The price is CA $121
CA $303 total
includes taxes & fees
May 31 - Jun 1
Civic Center, River Front, WALK to Mayo Clinic!! GARAGE Parking!
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
10.0 out of 10, Exceptional, 20 reviews
"Beautiful house! Clean and very spacious. Nice neighborhood. Would definitely stay here again!"
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
Oasis Luxe Suite—Steps from Mayo Clinic Hospital
10.0 out of 10, Exceptional, 8 reviews
"This accommodation was perfect for us. Location was so close to St Marys and let cal restaurants. Shuttle to Mayo worked out well. Well supplied. Can opener needs to be replaced and you need a church key. Extremely clean and comfortable."
Oasis Luxe Suite—Steps from Mayo Clinic Hospital
Five Star-3 Bedroom Showstopper Near Mayo Clinic
9.4 out of 10, Exceptional, 6 reviews
"John was an excellent owner to work with. Very prompt in answering questions and messages. He has an adorable home that was perfect for our week long stay. I would highly recommend it."
The price is CA $130
CA $365 total
includes taxes & fees
Jun 10 - Jun 11
Five Star-3 Bedroom Showstopper Near Mayo Clinic
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.
9.8 out of 10, Exceptional, 34 reviews
"We were very pleased with having this house to return to every day. We were here for Dr. Appointments for 1 month and this was perfect. It had everything we could have wanted or needed. We loved the trails right outside the door that can take you all over the city. Great location and very nice neighborhood."
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.
Magical Nest Hideaway
10.0 out of 10, Exceptional, 97 reviews
"I couldn’t be happier with our stay in the beautiful Magical Nest! Our hosts were exquisitely friendly, our studio was cute, cozy, spotless, and everything we could possibly want. I would DEFINITELY stay here again in the future! THANK YOU!!"
Magical Nest Hideaway
Park in the Garage and Walk to Mayo Clinic
10.0 out of 10, Exceptional, 40 reviews
"We spent 6 nights while visiting Mayo. House was clean, comfortable beds, great linens (super fluffy bath towels) and well stocked kitchen. Close enough to walk to Mayo, which we did on several occasions. We enjoyed the back porch and fish pond too."
Park in the Garage and Walk to Mayo Clinic
Euro House, Spacious! Near Mayo-Private Home
10.0 out of 10, Exceptional, 22 reviews
"Looking forward to staying here again. Convenient to restaurants and supermarkets. Very responsive host. Overall a great experience in a picture perfect neighborhood cottage. Maybe 5 minutes to Mayo Clinic by car."
Euro House, Spacious! Near Mayo-Private Home
Great Family Home, Fenced Yard, Pet Friendly, 2 mi from Mayo
10.0 out of 10, Exceptional, 20 reviews
"We were in town for a wedding this past weekend and loved that we chose to go this route for our stay. We were traveling with 6 total people and the layout of the house still felt spacious. The communication between the owners was second to none and we loved the location. We weren't able to take in all Rochester had to offer, but if you were there to do that, the location is perfect. I would have to guess 10 minutes or less to anything and everything you could really want to do. 5* for sure and...
Great Family Home, Fenced Yard, Pet Friendly, 2 mi from Mayo
Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.
10.0 out of 10, Exceptional, 1 review
"I booked for a stay for appts at Mayo. There were just two of us. The home is well situated for Mayo it’s a quick trip!! It’s also well located in terms of needing to run for coffee, restaurants, to the grocery store…etc. all things we found near. The home is very organized, clutter free and cheerfully decorated in bright colors. It’s equipped with modern lighting, heating and sound systems. The floors are heated in the basement and bathroom which was lovely!! The kitchen is well equipped and...
The price is CA $94
CA $259 total
includes taxes & fees
Jun 17 - Jun 18
Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.
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See all available properties in Byron
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Byron Vacation Rental Travel Info

Other types of properties in Byron you may be interested in

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
8.0 out of 10, Very good, 309 reviews
"Friendly staff with helpful information "
The price is CA $111
CA $128 total
includes taxes & fees
Jun 5 - Jun 6
AmericInn by Wyndham Rochester Near Mayo Clinic
Kahler Grand Hotel
3.0 star property
8.2 out of 10, Very good, 1,005 reviews
"There was a renovation ongoing and not fair to answer question about property conditions and facilities."
The price is CA $203
CA $234 total
includes taxes & fees
Jun 8 - Jun 9
Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
7.6 out of 10, Good, 1,203 reviews
"We checked out but needed to extend our parking a little so Mayo appointments could be finished….they did this graciously….."
The price is CA $158
CA $182 total
includes taxes & fees
Jun 3 - Jun 4
Kahler Inn and Suites - Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Byron. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Byron?

Yes, we offer vacation rentals close to popular attractions in Byron, or you can go with a more secluded option if you want a relaxing place to stay. Byron is known for its zoo and golf courses. Make sure you have time to check out the bars and parks during your trip.

What's the top vacation rental that Byron has to offer?

"Walden Pond" Adventure Amidst 44 Private Acres: Visitors like this Byron vacation home rental. It is located on a river and has a fireplace, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games.

What’s there to see and do in Byron?

While exploring the area, visit family-friendly sights like Minnesota Children's Museum, or get outside and enjoy nature at Oxbow Park. Salem Glen Winery and Apache Mall are a couple of places you'll find in the larger area.

What’s a vacation rental in Byron like?

A vacation rental is a private property you can stay in for a few weeks or just a few days in Byron. Vacation rentals offer amenities like laundry facilities and kitchens so your stay will be comfortable. If you're concerned about a sanitized environment, a vacation rental can offer a sense of safety away from public hotel elevators and busy reception areas while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a great option for a family getaway.

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