Byron Vacation Packages

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Your Byron Vacation

Book a tailored Byron vacation package that includes only the things you need and nothing you don't. Good for bars and pubs, history and culture, think about staying in the neighborhood of Downtown Rochester. There's plenty to put on your must-do list during your trip to Byron, starting with leading attractions such as Oxbow Park and Douglas Trail. A couple of quick clicks is all it takes to put together the ultimate Byron vacation on Expedia.

Ready to book your vacation to Byron?

 

Choose your dates

Byron Hotel Deals

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is CA $106 per night from Jul 27 to Jul 28
CA $106
CA $122 total
Jul 27 - Jul 28
includes taxes & fees
8/10 Very Good! (945 reviews)
"Nice large rooms, good dining options on site"

Reviewed on Jul. 21, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is CA $175 per night from Aug 24 to Aug 25
CA $175
CA $202 total
Aug 24 - Aug 25
includes taxes & fees
8.2/10 Very Good! (1,465 reviews)
"So convenient to the Mayo Clinic to which it is connected. Biggest minus is the parking which is owned by the city and makes going in and out difficult and expensive(at times the parking was added to the room which made it much more convenient than having to give your Visa card every time going in ..."

Reviewed on Jul. 22, 2025

Kahler Grand Hotel
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is CA $109 per night from Aug 8 to Aug 9
CA $109
CA $125 total
Aug 8 - Aug 9
includes taxes & fees
7.8/10 Good! (1,012 reviews)
"It is an average hotel. Is also old, carpet and walls need to be updated. You get what you pay. It was not that expensive hotel. So, i guess is worth the money."

Reviewed on Jul. 22, 2025

Med City Inn & Suites - Mayo Clinic Area
See all 373 properties in Byron
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
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Frequently asked questions

How much does a Byron vacation package cost?
You'll find cheap prices on Expedia for your Byron break. However, factors like the hotel choice, length of stay and season will influence how much your vacation to Byron costs.
What are the cheapest months to go to Byron?
January, February and November are great times to look for cheap Byron vacation packages. Opting to travel in quieter periods means you can typically find lower prices on hotels and flights.
How many days is enough for Byron?
With a well-planned schedule, you can easily visit the most popular Byron sights in a handful of days. But if you'd like to discover hidden gems or go on day trips, consider booking your Byron vacation for longer.
How to find the best Byron package deals?
Landing a cheap Byron package deal is a breeze with Expedia. After you've entered your destination and travel dates under our "Packages" tab, set your budget range, add a couple of filters and see what's available. You can tweak your search by "Property class," "Number of bedrooms," "Traveller experience" and more. Order the results by "Price: low to high" to view the most wallet-friendly Byron package deals. Want a simple trick to get even more savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are generally lower.
Is it cheaper to book a Byron vacation as a package?
You can enjoy significant savings on your Byron escape by booking a customized vacation package. Check the "Package" heading, then select your destination and travel dates to browse the best airfares and hotel prices. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Byron?
If you've got your Byron travel dates finalized, book early to score some unbeatable deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spontaneous adventures? Our last-minute deals are perfect for quick escapes.
How to plan a trip to Byron?

  1. Pick your dates: What you plan to do in Byron and your favourite season can help you decide when to get away.
  2. Budget wisely: In addition to the cost of your stay, you'll need to consider other expenses too. These include food, transportation and flights. Also, set aside some extra funds for unexpected costs that may crop up during your trip to Byron.
  3. Decide how long to go away for: Now that you're up to speed on Byron, you can figure out the perfect length of your break. Pull together a rough itinerary and allocate enough time to get through everything on your must-do list.
  4. Combine your airfare and accommodations: After you've settled on your trip dates and duration, book the perfect Byron vacation package for you.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.