Title: Best Hotels Near Byron Town Square, Byron from CA $96 | Expedia.ca

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## Check prices for these dates

Tonight

[Feb 22 - Feb 23](https://www.expedia.ca/Hotel-Search?regionId=920055695366561792&startDate=2026-02-22&endDate=2026-02-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 23 - Feb 24](https://www.expedia.ca/Hotel-Search?regionId=920055695366561792&startDate=2026-02-23&endDate=2026-02-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=920055695366561792&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=920055695366561792&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for Byron Town Square hotels

![Exterior](https://images.trvl-media.com/lodging/10000000/9480000/9478000/9477908/16fa1f7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast area](https://images.trvl-media.com/lodging/10000000/9480000/9478000/9477908/8ba09ac8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/10000000/9480000/9478000/9477908/a3f10cf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, desk, blackout drapes](https://images.trvl-media.com/lodging/10000000/9480000/9478000/9477908/3c05dccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn & Suites West - Medical Center

[](https://www.expedia.ca/Rochester-Hotels-Comfort-Inn-Suites-West-Medical-Center.h9477908.Hotel-Information)

8.8 km from Byron Town Square

9.0/10

Wonderful

(556 reviews)

"Was a nice place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Pam

CA $108

CA $125 total

includes taxes & fees

Mar 20 - Mar 21

[](https://www.expedia.ca/Rochester-Hotels-Comfort-Inn-Suites-West-Medical-Center.h9477908.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/3000000/2830000/2825400/2825336/f5dad376.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, open 6 AM to midnight, sun loungers](https://images.trvl-media.com/lodging/3000000/2830000/2825400/2825336/2358f135.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Two queens bed non smoking](https://images.trvl-media.com/lodging/3000000/2830000/2825400/2825336/39857682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2830000/2825400/2825336/be898197.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Rochester-North

[](https://www.expedia.ca/Rochester-Hotels-Hampton-Inn-Suites-Rochester-North.h2825336.Hotel-Information)

11.2 km from Byron Town Square

9.2/10

Wonderful

(1,002 reviews)

"Good staff great place "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Juan

CA $133

CA $153 total

includes taxes & fees

Mar 15 - Mar 16

[](https://www.expedia.ca/Rochester-Hotels-Hampton-Inn-Suites-Rochester-North.h2825336.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/18000000/17290000/17289900/17289857/07179e13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, Multiple Beds, Accessible, Non Smoking (Efficiency, Upgrade)](https://images.trvl-media.com/lodging/18000000/17290000/17289900/17289857/c9ae5c91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/18000000/17290000/17289900/17289857/b9c5b46e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17290000/17289900/17289857/e261cbb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sleep Inn & Suites West-Near Medical Center

[](https://www.expedia.ca/Rochester-Hotels-Sleep-Inn-Suites-West-Near-Medical-Center.h17289857.Hotel-Information)

8.7 km from Byron Town Square

9.0/10

Wonderful

(607 reviews)

"It was a quiet place to stay. The rooms were clean and the staff was polite."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laurie

CA $120

CA $139 total

includes taxes & fees

Mar 20 - Mar 21

[](https://www.expedia.ca/Rochester-Hotels-Sleep-Inn-Suites-West-Near-Medical-Center.h17289857.Hotel-Information)

![Indoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3837h2560x3y0-1092e125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2560x4y0-89209858.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room)](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/ec5f8616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room)](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/d609b8e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

[](https://www.expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information)

11.7 km from Byron Town Square

8.4/10

Very good

(827 reviews)

"Check in staff was great! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paulette

CA $108

CA $125 total

includes taxes & fees

Feb 23 - Feb 24

[](https://www.expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/10000000/9420000/9416900/9416882/ecc192a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9420000/9416900/9416882/2a3df201.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, 1 Queen Bed, Kitchen](https://images.trvl-media.com/lodging/10000000/9420000/9416900/9416882/04774547.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/10000000/9420000/9416900/9416882/9de62871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Staybridge Suites Rochester - Commerce Dr NW by IHG

[](https://www.expedia.ca/Rochester-Hotels-Staybridge-Suites-Rochester-Commerce-Dr-NW.h9416882.Hotel-Information)

8.8 km from Byron Town Square

8.8/10

Excellent

(519 reviews)

"Staff very helpful and friendly. Room clean and spacious for our four adults and a baby."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amanda

CA $136

CA $156 total

includes taxes & fees

Mar 1 - Mar 2

[](https://www.expedia.ca/Rochester-Hotels-Staybridge-Suites-Rochester-Commerce-Dr-NW.h9416882.Hotel-Information)

![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/1b6617d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/fdc1ffe6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/0c1d91fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/43d012a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

[](https://www.expedia.ca/Rochester-Hotels-Microtel-Inn-Suites-By-Wyndham-Rochester-North-Mayo-Clinic.h116574.Hotel-Information)

10.6 km from Byron Town Square

8.0/10

Very good

(1,002 reviews)

"Clean room, decent breakfast choices "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Connie

CA $84

CA $96 total

includes taxes & fees

Feb 27 - Feb 28

[](https://www.expedia.ca/Rochester-Hotels-Microtel-Inn-Suites-By-Wyndham-Rochester-North-Mayo-Clinic.h116574.Hotel-Information)

![2 indoor pools](https://images.trvl-media.com/lodging/1000000/480000/473100/473100/91eb68fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/480000/473100/473100/51f9562a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/480000/473100/473100/9070c6cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/480000/473100/473100/0ac076f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TownePlace Suites by Marriott Rochester

[](https://www.expedia.ca/Rochester-Hotels-TownePlace-Suites-By-Marriott-Rochester.h473100.Hotel-Information)

10.4 km from Byron Town Square

8.8/10

Excellent

(552 reviews)

"My kids really enjoyed the pool, and so did I! Room was nice & clean. Staff were nice. I really appreciated the late checkout. (At least compared to other hotels, 12pm is late!) "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ashley

CA $134

CA $154 total

includes taxes & fees

Mar 1 - Mar 2

[](https://www.expedia.ca/Rochester-Hotels-TownePlace-Suites-By-Marriott-Rochester.h473100.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/11000000/10950000/10947300/10947270/9bad372e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/11000000/10950000/10947300/10947270/272574f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/11000000/10950000/10947300/10947270/70edacbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/11000000/10950000/10947300/10947270/c8e01189.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

[](https://www.expedia.ca/Rochester-Hotels-Fairfield-Inn-Suites-Rochester-Mayo-Clinic-AreaSt-Marys.h10947270.Hotel-Information)

11.2 km from Byron Town Square

9.6/10

Exceptional

(692 reviews)

"Clean rooms with all necessities and a wonderful front desk staff. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Barbara

CA $134

CA $155 total

includes taxes & fees

Mar 21 - Mar 22

[](https://www.expedia.ca/Rochester-Hotels-Fairfield-Inn-Suites-Rochester-Mayo-Clinic-AreaSt-Marys.h10947270.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/c7dc0b32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/00ce891c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/86a7bf04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio, 1 Queen Bed | Living area](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/5b3222d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spark by Hilton Rochester South

[](https://www.expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information)

15.8 km from Byron Town Square

9.4/10

Exceptional

(379 reviews)

"Clean, quiet and a really nice place to stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tony

CA $94

CA $108 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information)

![Courtyard](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast and dinner served](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/fc2af524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/9472e74e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/6a0aeefd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### EVEN Hotel Rochester - Mayo Clinic Area by IHG

[](https://www.expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information)

11.9 km from Byron Town Square

9.4/10

Exceptional

(1,013 reviews)

"Great hotel!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Narcedalia

CA $136

CA $159 total

includes taxes & fees

Feb 26 - Feb 27

[](https://www.expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/444e106b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/39073559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, pillowtop beds, minibar](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/560201a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 indoor pools](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/7ee0db4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Home2 Suites by Hilton Rochester Mayo Clinic Area

[](https://www.expedia.ca/Rochester-Hotels-Home2-Suites-By-Hilton-Rochester-Mayo-Clinic-Area.h23512633.Hotel-Information)

12.6 km from Byron Town Square

9.6/10

Exceptional

(917 reviews)

"Staff, room and breakfast were wonderful!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

DeLaine

CA $167

CA $192 total

includes taxes & fees

Mar 1 - Mar 2

[](https://www.expedia.ca/Rochester-Hotels-Home2-Suites-By-Hilton-Rochester-Mayo-Clinic-Area.h23512633.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/404886d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/b56a9dd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/7b237c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/00440028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aspen Suites

[](https://www.expedia.ca/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information)

11.7 km from Byron Town Square

9.0/10

Wonderful

(731 reviews)

"Very clean and nice staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kirk

[](https://www.expedia.ca/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/5776b64a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/9c4ccb32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Billiards](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/6b44b2f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/50c22b07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Berkman

[](https://www.expedia.ca/Rochester-Hotels-Berkman-Hotel.h46291477.Hotel-Information)

11.5 km from Byron Town Square

9.6/10

Exceptional

(385 reviews)

"Everything was excellent, second time staying there. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carolyn

CA $185

CA $215 total

includes taxes & fees

Feb 25 - Feb 26

[](https://www.expedia.ca/Rochester-Hotels-Berkman-Hotel.h46291477.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/7b075080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/9d267d23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/95d550d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/d3281bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Residence Inn by Marriott Rochester Mayo Clinic Area South

[](https://www.expedia.ca/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area-South.h90610605.Hotel-Information)

12.7 km from Byron Town Square

9.6/10

Exceptional

(266 reviews)

"Staff was great and helpful, lovely room!, quiet area, restaurants nearby"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ann Marie

CA $187

CA $216 total

includes taxes & fees

Mar 6 - Mar 7

[](https://www.expedia.ca/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area-South.h90610605.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/c73455d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/be8f1f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/d590e034.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/52c02e28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Rochester-South

[](https://www.expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information)

13.6 km from Byron Town Square

9.0/10

Wonderful

(1,005 reviews)

"Was a clean room that we had the hotel was quiet at night, friendly staff, and a very good breakfast buffet"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Larry

CA $108

CA $124 total

includes taxes & fees

Mar 21 - Mar 22

[](https://www.expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information)

![Interior entrance](https://images.trvl-media.com/lodging/1000000/910000/906700/906635/99cea113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/1000000/910000/906700/906635/daa559a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/910000/906700/906635/1cd9a36e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/910000/906700/906635/f81bde8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont by Wyndham Kasson Rochester Area

[](https://www.expedia.ca/Rochester-Hotels-Baymont-By-Wyndham-Kasson-Rochester-Area.h906635.Hotel-Information)

9.7 km from Byron Town Square

6.6/10

(379 reviews)

"Room was dirty and neglected ceiling has mold and heater didn't work was gorrible"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Heleena

CA $100

CA $107 total

includes taxes & fees

Mar 1 - Mar 2

[](https://www.expedia.ca/Rochester-Hotels-Baymont-By-Wyndham-Kasson-Rochester-Area.h906635.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/5000000/4920000/4913700/4913635/90393dc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/5000000/4920000/4913700/4913635/79a3373a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/5000000/4920000/4913700/4913635/9fcb392a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/5000000/4920000/4913700/4913635/a7ddf3d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

[](https://www.expedia.ca/Rochester-Hotels-Holiday-Inn-Express-Suites-Rochester-Mayo-Clinic-Area.h4913635.Hotel-Information)

11.3 km from Byron Town Square

8.8/10

Excellent

(777 reviews)

"the staff was friendly and helpful/ and the room was clean/ and good amenities"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

carol

CA $152

CA $175 total

includes taxes & fees

Mar 1 - Mar 2

[](https://www.expedia.ca/Rochester-Hotels-Holiday-Inn-Express-Suites-Rochester-Mayo-Clinic-Area.h4913635.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/055a808d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Laundry room](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/231bcb83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/37e2c033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Econo Lodge Mayo Clinic Area

[](https://www.expedia.ca/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information)

13.8 km from Byron Town Square

9.0/10

Wonderful

(940 reviews)

"Very clean and staff was friendly. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert

CA $87

CA $101 total

includes taxes & fees

Mar 7 - Mar 8

[](https://www.expedia.ca/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1270000/1263400/1263391/b39d1efa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Flat-screen TV, Netflix](https://images.trvl-media.com/lodging/2000000/1270000/1263400/1263391/194d3b8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/2000000/1270000/1263400/1263391/e31f1fad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed](https://images.trvl-media.com/lodging/2000000/1270000/1263400/1263391/288dd4d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

[](https://www.expedia.ca/Rochester-Hotels-Courtyard-By-Marriott-Rochester-Mayo-Clinic-AreaSaint-Marys.h1263391.Hotel-Information)

11.5 km from Byron Town Square

9.2/10

Wonderful

(788 reviews)

"Room was clean and the housekeeping person very helpful and courteous "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dawn

CA $194

CA $224 total

includes taxes & fees

Mar 8 - Mar 9

[](https://www.expedia.ca/Rochester-Hotels-Courtyard-By-Marriott-Rochester-Mayo-Clinic-AreaSaint-Marys.h1263391.Hotel-Information)

![Pub](https://images.trvl-media.com/lodging/70000000/69690000/69681200/69681188/ed3fe960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/70000000/69690000/69681200/69681188/5817de71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Studio, 1 Double Bed, City View, Corner](https://images.trvl-media.com/lodging/70000000/69690000/69681200/69681188/7a89a125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/70000000/69690000/69681200/69681188/2f1620a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TownePlace Suites by Marriott Rochester Mayo Clinic Area

[](https://www.expedia.ca/Rochester-Hotels-TownePlace-Suites-By-Marriott-Rochester-Mayo-Clinic-Area.h69681188.Hotel-Information)

12.5 km from Byron Town Square

9.6/10

Exceptional

(498 reviews)

"Staff was very helpful. Room was spacious and beds were very comfortable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lisa

CA $174

CA $200 total

includes taxes & fees

Mar 7 - Mar 8

[](https://www.expedia.ca/Rochester-Hotels-TownePlace-Suites-By-Marriott-Rochester-Mayo-Clinic-Area.h69681188.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-08&endDate=2026-03-09&regionId=920055695366561792&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Compare popular hotels close to Byron Town Square

| Property                                                                                                                                                                                                                                                          | Star rating       | Guest rating              | Breakfast included | Pool | Spa | Pet-friendly | WiFi included |  |
| ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- |  |
| ![Exterior](https://images.trvl-media.com/lodging/10000000/9480000/9478000/9477908/16fa1f7c.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Comfort Inn & Suites West - Medical Center                                                                                | 3.0 star property | 9.0Wonderful556 reviews   | View               |      |     |              |               |  |
| ![Restaurant](https://images.trvl-media.com/lodging/3000000/2830000/2825400/2825336/f5dad376.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hampton Inn & Suites Rochester-North                                                                                     | 2.5 star property | 9.2Wonderful1,002 reviews | View               |      |     |              |               |  |
| ![Lobby](https://images.trvl-media.com/lodging/18000000/17290000/17289900/17289857/07179e13.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Sleep Inn & Suites West-Near Medical Center                                                                               | 2.5 star property | 9.0Wonderful607 reviews   | View               |      |     |              |               |  |
| ![Indoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3837h2560x3y0-1092e125.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Best Western Rochester Hotel Mayo Clinic Area/St. Mary's | 2.5 star property | 8.4Very good827 reviews   | View               |      |     |              |               |  |
| ![Exterior](https://images.trvl-media.com/lodging/10000000/9420000/9416900/9416882/ecc192a1.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Staybridge Suites Rochester - Commerce Dr NW by IHG                                                                       | 3.0 star property | 8.8Excellent519 reviews   | View               |      |     |              |               |  |

## Top Byron Town Square Hotel Reviews

![SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/39da8a7c_y.jpg)

### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

10/10 Excellent

"Was not the original place I thought we were staying at but were pleasantly surprized. Nice, clean, great staff. Close to the hospital. Would definitely recommend and stay there again. "

[](https://expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information)

![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg)

### Kahler Grand Hotel

10/10 Excellent

"Worked to accommodate our needs. "

[](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information)

![Kahler Inn and Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg)

### Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

"Nice room nice staff and easy to get to the clinic "

[](https://expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information)

![EVEN Hotel Rochester - Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_y.jpg)

### EVEN Hotel Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Great room and location"

[](https://expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information)

![Comfort Inn & Suites West - Medical Center](https://images.trvl-media.com/lodging/10000000/9480000/9478000/9477908/b825a8ac_y.jpg)

### Comfort Inn & Suites West - Medical Center

10/10 Excellent

"Clean and comfortable. Great location and friendly staff"

[](https://expedia.ca/Rochester-Hotels-Comfort-Inn-Suites-West-Medical-Center.h9477908.Hotel-Information)

![Hyatt House Rochester/Mayo Clinic Area](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/369065b1_y.jpg)

### Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"Very nice staff rooms were great"

[](https://expedia.ca/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information)

![Staybridge Suites Rochester - Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/60000000/59810000/59802900/59802871/2feb2cc1_y.jpg)

### Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Clean room"

[](https://expedia.ca/Rochester-Hotels-Staybridge-Suites-Rochester-St-Marys-Area.h59802871.Hotel-Information)

![Aspen Suites](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658_y.jpg)

### Aspen Suites

10/10 Excellent

"The food and staff were awesome. It was also nice to have underground parking in the winter. "

[](https://expedia.ca/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information)

![Hotel Indigo Rochester – Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg)

### Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"Excellent service, above and beyond. Very nice hotel and rooms were perfect. Convenient access to Mayo. My only complaints would be no microwave in rooms and no help with luggage. Just had my leg amputated. "

[](https://expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information)

## Hotels near other Byron Town Square attractions

### High Point Shopping Center

You can search for that perfect souvenir at High Point Shopping Center during your trip to Byron. Amble around the area's parks or experience its art scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=920055692390768640)

### Valley View Park

Valley View Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=920054436704165888)

### Somerby Park

Somerby Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=920054500901974016)

### Community Center Park

Community Center Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=920054840900820992)

### East Brookfield Park

After visiting East Brookfield Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=920054803617718272)

### Links of Byron Mini Golf

Enjoy a round of golf in Byron at Links of Byron Mini Golf. Amble around the area's parks or experience its art scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=920055674416046080)

### Brook Lawn Park

After visiting Brook Lawn Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=920054881648549888)

### Somerby Golf Club

Enjoy a round of golf in Byron at Somerby Golf Club. Amble around the area's parks or experience its art scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=920055666543357952)

## Frequently asked questions

### What's the area like around Byron Town Square?

### Where is the best place to stay close to Byron Town Square?

### How many hotels can I expect to find near Byron Town Square?

### If I need to cancel the hotel reservation for my stay near Byron Town Square, will I receive a refund?

### What can I see and do near Byron Town Square?