Beginning of main content

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Top Trending Hotels Near Buffalo Museum of Science, Buffalo

See all 150 Hotels near Buffalo Museum of Science
Hotel at the Lafayette A Trademark Collection Hotel

Hotel at the Lafayette A Trademark Collection Hotel

391 Washington St, Buffalo
4.0 out of 5.0
Last booking: 41 minutes ago
1 others viewing this property now

Located in Downtown Buffalo, this hotel is within a 10-minute walk of Main Place Mall and Coca-Cola Field. Pierce - Arrow Museum and Buffalo and Erie County ...

Get Rates

Get Rates
Adam's Mark Buffalo

Adam's Mark Buffalo

120 Church St, Buffalo
3.5 out of 5.0
Last booking: 4 hours ago
22 others viewing this property now

This downtown hotel is a half-mile from First Niagara Center and Coca-Cola Field; Niagara Falls is 20 miles away.

C$89

C$89
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

Two Fountain Plaza, Buffalo
4.0 out of 5.0
Last booking: 7 hours ago
27 others viewing this property now

Facing Main Street and the trolley, Hyatt Regency Buffalo / Hotel and Conference Center has direct access to the convention center and is within 3 blocks of ...

C$146

C$146
Hampton Inn & Suites Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown

220 Delaware Ave, Buffalo
3.5 out of 5.0
Last booking: 23 hours ago
6 others viewing this property now

Located in Chippewa District, this hotel is within 1 mi (2 km) of Fountain Plaza, Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site, and Coca-Cola ...

Get Rates

Get Rates
Curtiss Hotel, An Ascend Hotel Collection Member

Curtiss Hotel, An Ascend Hotel Collection Member

210 Franklin St, Buffalo
5.0 out of 5.0
Last booking: 1 hour ago
9 others viewing this property now

Located in Downtown Buffalo, this hotel is within a 10-minute walk of Shea's Performing Arts Center and Guaranty / Prudential Building. Coca-Cola Field and Canalside ...

Get Rates

Get Rates
Holiday Inn Express & Suites Buffalo Downtown

Holiday Inn Express & Suites Buffalo Downtown

601 Main St, Buffalo
2.5 out of 5.0
Last booking: 1 hour ago

Located in Buffalo Theater District, this hotel is steps from Market Arcade Building, CEPA Gallery, and Buffalo Visitor Center. Tralf Music Hall and Fountain ...

Get Rates

Get Rates
Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown

125 High St, Buffalo
3.5 out of 5.0
Last booking: 6 hours ago
2 others viewing this property now

This family-friendly Buffalo hotel is located in the business district, within a 15-minute walk of Buffalo General Medical Center and Wilcox Mansion - Theodore ...

C$134

C$134
Oscar's Bed & Breakfast

Oscar's Bed & Breakfast

288 Linwood Avenue, Buffalo
4.0 out of 5.0

Located in Downtown Buffalo, this bed & breakfast is within a 15-minute walk of Cofeld Judaic Museum, African American Cultural Center, and Benjaman Gallery. ...

Get Rates

Get Rates
Best Western on the Avenue

Best Western on the Avenue

510 Delaware Avenue, Buffalo
3.0 out of 5.0
Last booking: 27 minutes ago
2 others viewing this property now

Located in Allentown, this hotel is within a 15-minute walk of Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site and Kleinhans Music Hall. ...

Get Rates

Get Rates
The Westin Buffalo

The Westin Buffalo

250 Delaware Ave, Buffalo
4.5 out of 5.0
Last booking: 49 minutes ago
2 others viewing this property now

Located in Chippewa District, this hotel is within 1 mi (2 km) of Fountain Plaza, Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site, and Coca-Cola ...

Get Rates

Get Rates

Buffalo Museum of Science Hotel Guide

Explore the sights, discover the sounds, and immerse yourself in the city’s atmosphere: When you book a vacation at the top hotels near Buffalo Museum of Science, you’ll be in the best place to do it all. These properties are renowned for their central locations and comforting amenities, and the range of options lets you personalize your getaway to suit your travelling style.

Book a stay at one of the luxury hotels close to Buffalo Museum of Science to enjoy the first-class restaurants and spas, or grab one of the Buffalo Museum of Science hotel deals, if you want to save a few dollars on an inexpensive trip. Who knows? When you book with Expedia.ca, you might even find sale rates and deep discounts on the most popular Buffalo Museum of Science hotel.

Whether you’re heading out on a business trip or taking your family on yearly holiday, tracking down a cheap deal on Buffalo Museum of Science hotels in Buffalo Museum of Science gives you the opportunity to wander around the local attractions without sacrificing your budget.