- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Southeast Missouri 3-star hotels

1. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,002 reviews)
The price is CA $133
CA $153 total
includes taxes & fees
Nov 22 - Nov 23

2. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,005 reviews)
The price is CA $141
CA $159 total
includes taxes & fees
Nov 16 - Nov 17

3. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
8.8 out of 10, Excellent, (896 reviews)
The price is CA $113
CA $122 total
includes taxes & fees
Nov 16 - Nov 17

4. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (242 reviews)
The price is CA $143
CA $161 total
includes taxes & fees
Nov 19 - Nov 20

5. Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Hayti CaruthersvilleHayti
9.2 out of 10, Wonderful, (1,001 reviews)
The price is CA $138
CA $158 total
includes taxes & fees
Nov 22 - Nov 23

6. Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (1,001 reviews)
The price is CA $127
CA $144 total
includes taxes & fees
Nov 15 - Nov 16

7. Holiday Inn Poplar Bluff by IHG
Holiday Inn Poplar Bluff by IHGPoplar Bluff
8.8 out of 10, Excellent, (806 reviews)
The price is CA $112
CA $126 total
includes taxes & fees
Dec 11 - Dec 12

8. Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
The price is CA $127
CA $143 total
includes taxes & fees
Nov 19 - Nov 20

9. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,003 reviews)
The price is CA $113
CA $119 total
includes taxes & fees
Nov 22 - Nov 23

10. La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis SouthFestus
7.8 out of 10, Good, (1,006 reviews)
The price is CA $119
CA $136 total
includes taxes & fees
Nov 15 - Nov 16

11. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (559 reviews)
The price is CA $164
CA $186 total
includes taxes & fees
Nov 19 - Nov 20

12. Century Casino & Hotel Caruthersville
Century Casino & Hotel CaruthersvilleCaruthersville
8.6 out of 10, Excellent, (204 reviews)
The price is CA $165
CA $187 total
includes taxes & fees
Dec 10 - Dec 11

13. Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (978 reviews)
The price is CA $137
CA $155 total
includes taxes & fees
Nov 22 - Nov 23

14. Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.4 out of 10, Very good, (409 reviews)
The price is CA $134
CA $146 total
includes taxes & fees
Dec 11 - Dec 12

15. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (118 reviews)
The price is CA $155
CA $177 total
includes taxes & fees
Nov 19 - Nov 20

16. Current River Inn
Current River InnVan Buren
8.2 out of 10, Very good, (224 reviews)
The price is CA $154
CA $166 total
includes taxes & fees
Nov 16 - Nov 17

17. Baymont by Wyndham Festus
Baymont by Wyndham FestusFestus
6.8 out of 10, (1,002 reviews)
The price is CA $95
CA $109 total
includes taxes & fees
Dec 11 - Dec 12

18. TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (31 reviews)
The price is CA $154
CA $175 total
includes taxes & fees
Nov 19 - Nov 20

19. Johnson's Shut-ins State Park
Johnson's Shut-ins State ParkMiddle Brook
10.0 out of 10, Exceptional, (3 reviews)

20. Urban Lofts
Urban LoftsPerryville
9.4 out of 10, Exceptional, (22 reviews)
The price is CA $285
CA $439 total
includes taxes & fees
Nov 24 - Nov 25
Top Southeast Missouri Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
































































