Title: 2 Stars Hotels in Depew, Buffalo from CA $96 - Find Cheap Depew Hotels With 2 Stars | Expedia.ca [Depew Travel Guide](https://expedia.ca/Depew.dx6338362)[Hotels in Depew](https://expedia.ca/Depew-Hotels.d6338362.Travel-Guide-Hotels)[Vacation Rentals in Depew](https://expedia.ca/Depew-Vacation-Rentals.d6338362.Travel-Guide-VacationRentals)[Flights to Depew](https://expedia.ca/Cheap-Flights-To-Depew.d6338362.Travel-Guide-Flights)[Things to do in Depew](https://expedia.ca/Things-To-Do-In-Depew.d6338362.Travel-Guide-Activities)[Depew Car Rentals](https://expedia.ca/Car-Rentals-In-Depew.d6338362.Car-Rental-Guide)[Depew Vacation Packages](https://expedia.ca/Depew.d6338362.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 2 Stars Hotels in Depew, Buffalo from CA $96 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Depew 2 Star Hotels Tonight [Oct 12 - Oct 13](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2025-10-12&endDate=2025-10-13&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 13 - Oct 14](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2025-10-13&endDate=2025-10-14&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Depew 2 Star Hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2200/2196/a1859ccd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2200/2196/w2990h2005x0y16-ce4bee0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2200/2196/bb96b384.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/10000/2200/2196/7c123407.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairbridge Inn Express Buffalo Airport Williamsville Buffalo 4.6/10 (1020) "Basic room but for the price paid overall very happy. " CA $84 CA $96 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Buffalo-Hotels-FairBridge-Inn-Express-Buffalo-Airport-Williamsville.h2196.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/ae021a7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/96e4ab82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/65fc1711.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, Non Smoking (2 Double Beds & Sofa Bed)](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/278a83c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Buffalo Airport Buffalo 8.0/10 Very good (1768) "next to airport and very affordable " CA $92 CA $105 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Buffalo-Hotels-Sleep-Inn-Suites-Buffalo-Airport.h85007.Hotel-Information) ![Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/50c6a12d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/f90ffba2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/3274a349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/ea0d463b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Grand Island - Niagara Falls by IHG Grand Island 8.8/10 Excellent (1481) "Great stay!" CA $125 CA $142 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/66600/66581/2db1a2f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/70000/66600/66581/bd6d68a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/66600/66581/a57eee4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/70000/66600/66581/fe3bf14f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn University Buffalo 8.0/10 Very good (1126) "Excellent stay" CA $146 CA $166 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Buffalo-Hotels-Comfort-Inn-University.h66581.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/76400/76371/66013c67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/80000/76400/76371/4fbfceee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/80000/76400/76371/73118da5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/80000/76400/76371/abe56549.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### CenterWay Hotel Tonawanda Tonawanda 7.8/10 Good (1013) "Good place to stay" CA $84 CA $96 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Buffalo-Hotels-CenterWay-Hotel-Tonawanda.h76371.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/50000/42200/42198/df50dbea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/42200/42198/f67f6806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/50000/42200/42198/68195744.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/50000/42200/42198/828a364a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Amherst, NY - Buffalo Buffalo 6.4/10 (1010) "Great hotel and they allow dogs! " CA $88 CA $100 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Buffalo-Hotels-Motel-6-Amherst.h42198.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8600/8561/0cd596c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8600/8561/36bfaffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8600/8561/e2191a46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio, 2 Double Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/1000000/10000/8600/8561/d792b5e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Extended Stay America Suites - Buffalo - Airport Buffalo 7.0/10 Good (949) "Nice place. Close to restaurants." CA $96 CA $109 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Buffalo-Hotels-Extended-Stay-America-Suites-Buffalo-Airport.h8561.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/51000000/50710000/50706500/50706489/63fc013f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/51000000/50710000/50706500/50706489/655c2793.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/51000000/50710000/50706500/50706489/41f0c04c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/51000000/50710000/50706500/50706489/115eb7cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Buffalo - Amherst, NY Buffalo 9.4/10 Exceptional (1880) "Very helpful staff and breakfast was plenty" CA $136 CA $154 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Buffalo-Hotels-Hampton-Inn-Buffalo-Amherst.h50706489.Hotel-Information) ![1 bedroom, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/73c0de62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/00c812b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/57951bef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/a56cf142.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG Downtown Buffalo 8.6/10 Excellent (1009) "Clean, nice staff, good breakfast" CA $139 CA $162 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Buffalo-Hotels-Holiday-Inn-Express-Suites-Buffalo-Downtown-Medical-CTR.h6258.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/c135a4a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/5febfbbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/098077ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/23031bfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Summit Inn Niagara Falls 8.6/10 Excellent (1372) "Clean room, very comfortable bed, friendly staff." CA $112 CA $128 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Niagara-Falls-Hotels-Best-Western-Summit-Inn.h5183.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/5207dfe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/6fe2d7de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/0e406b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/a196e14b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Near Walden Galleria Mall Buffalo 8.0/10 Very good (1026) "Good place for an overnight stay " CA $138 CA $157 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Buffalo-Hotels-Quality-Inn-Near-Walden-Galleria-Mall.h558591.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/7d3bff92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/b3c0a8a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/dec807b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/2c00fbc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Buffalo Inn & Suites Buffalo 8.8/10 Excellent (794) "Nice hotel and very convenient. " CA $138 CA $157 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Eva-Hotel.h99802648.Hotel-Information) ![Down comforters, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/21000000/20010000/20009600/20009524/716b44ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/21000000/20010000/20009600/20009524/89989c3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/21000000/20010000/20009600/20009524/80b636a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/21000000/20010000/20009600/20009524/1606524c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Niagara Falls Blvd USA La Salle 8.8/10 Excellent (1377) "Clean room, Friendly staff, Good free breakfast. " CA $114 CA $130 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Niagara-Falls-Hotels-Comfort-Inn-Suites-Niagara-Falls-Blvd-USA.h20009524.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2850000/2841800/2841764/fd480a3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/3000000/2850000/2841800/2841764/8fb47646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2850000/2841800/2841764/4074f60b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2850000/2841800/2841764/e564d189.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Buffalo Airport Buffalo 8.6/10 Excellent (1004) "Newer hotel, staff was amazing, gym had plenty of equipment. Will definitely stay again! " CA $189 CA $215 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Buffalo-Hotels-Fairfield-Inn-Suites-By-Marriott-Buffalo-Airport.h2841764.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/890400/890385/023ac782.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/900000/890400/890385/62f91443.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/900000/890400/890385/96595615.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/890400/890385/aa6d9829.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge At The Falls North La Salle 7.8/10 Good (1106) "Clean, decent place to stay for the money. " CA $89 CA $102 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Niagara-Falls-Hotels-Econo-Lodge-At-The-Falls-North.h890385.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/10000000/9680000/9680000/9679916/b02fadd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/10000000/9680000/9680000/9679916/382726c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/10000000/9680000/9680000/9679916/72bc6212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds](https://images.trvl-media.com/lodging/10000000/9680000/9680000/9679916/cb50b0a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AAshram Hotel by Niagara River La Salle 7.8/10 Good (1009) "Loved the stay here " CA $84 CA $96 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Niagara-Falls-Hotels-AAshram-Hotel-By-Niagara-River.h9679916.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/130000/126900/126836/a429a676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/130000/126900/126836/e8fdcb22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/126900/126836/08466402.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/130000/126900/126836/95db0ae4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn Buffalo 8.8/10 Excellent (1130) "Rooms were very clean and staff was great. Will stay again. " CA $133 CA $151 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Buffalo-Hotels-Sleep-Inn.h126836.Hotel-Information) ![Deluxe Room, 2 Double Beds (Smoke Free)](https://images.trvl-media.com/lodging/1000000/20000/17500/17404/01e5587d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/20000/17500/17404/a8136605.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17500/17404/8659347d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/20000/17500/17404/f1d7d9a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Buffalo – Hamburg/ I-90 Hamburg 6.0/10 (1014) "Hotel right next to the highway so not quiet. Room was clean, staff were hospitable. Great value while passing through the area. " CA $85 CA $97 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Hamburg-I-90.h17404.Hotel-Information) ![In-room safe, blackout drapes, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/30000/25400/25386/ef195e85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/25400/25386/a061f4c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25400/25386/63dd350a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/25400/25386/e1851f1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn - Niagara Falls Blvd La Salle 6.0/10 (1019) "Excellent place to rest, everything close" CA $82 CA $96 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Niagara-Falls-Hotels-Quality-Inn-Niagara-Falls.h25386.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/6000000/5320000/5313700/5313625/1a5b867a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/6000000/5320000/5313700/5313625/16f1f420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/6000000/5320000/5313700/5313625/93ad4fec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5320000/5313700/5313625/cf1a50f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Buffalo South I-90, NY Buffalo 8.2/10 Very good (1280) " The staff was wonderful and the breakfasts were the best." CA $178 CA $203 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Buffalo-Hotels-Country-Inn-Suites-By-Radisson.h5313625.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Depew-Hotels.s20-0-d6338362.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Depew-Hotels.s20-0-d6338362.Travel-Guide-Filter-Hotels) ## Explore similar 3-star hotels Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Depew. ![Buffalo Airport Hotel](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/90223c0d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Buffalo Airport Hotel 4600 Genesee St, Buffalo, NY CA $134 CA $152 total Nov 3 - Nov 4 includes taxes & fees 7.8/10 Good! (2,665 reviews) [](https://expedia.ca/Buffalo-Hotels-Buffalo-Airport-Hotel.h26001.Hotel-Information) ![M Hotel Buffalo](https://images.trvl-media.com/lodging/1000000/20000/11300/11231/2c4d5593_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### M Hotel Buffalo 2040 Walden Ave, Buffalo, NY CA $115 CA $130 total Oct 14 - Oct 15 includes taxes & fees 7.2/10 Good! (2,243 reviews) [](https://expedia.ca/Buffalo-Hotels-Millennium-Buffalo.h11231.Hotel-Information) ![Hyatt Regency Buffalo / Hotel and Conference Center](https://images.trvl-media.com/lodging/1000000/30000/23200/23101/00561234_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hyatt Regency Buffalo / Hotel and Conference Center Two Fountain Plaza, Buffalo, NY CA $149 CA $174 total Nov 4 - Nov 5 includes taxes & fees 8/10 Very Good! (1,582 reviews) [](https://expedia.ca/Buffalo-Hotels-Hyatt-Regency-Buffalo-Hotel-And-Conference-Center.h23101.Hotel-Information) Still don't see what you're looking for? [See all properties in Depew.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=6338362&star=20) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=6338362&star=20&star=20&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=6338362&star=20&star=20&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=6338362&star=20&star=20&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=6338362&star=20&star=20&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=6338362&star=20&star=20&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Depew Hotel Reviews ![CenterWay Hotel Tonawanda](//images.trvl-media.com/lodging/1000000/80000/76400/76371/66013c67_y.jpg) ### CenterWay Hotel Tonawanda 10/10 Excellent "The staff is great. " [](https://expedia.ca/Buffalo-Hotels-CenterWay-Hotel-Tonawanda.h76371.Hotel-Information) ![Motel 6 Amherst, NY - Buffalo](//images.trvl-media.com/lodging/1000000/50000/42200/42198/df50dbea_y.jpg) ### Motel 6 Amherst, NY - Buffalo 10/10 Excellent "Ok " [](https://expedia.ca/Buffalo-Hotels-Motel-6-Amherst.h42198.Hotel-Information) ## Find out more about Depew Want to get out of town on the cheap? Thanks to the low rates and great discounts at the top 2 Stars hotels in Depew, Depew you can sneak away on the trip of your dreams with plenty of cash to spare. In addition to the friendly staff and well-maintained surroundings, you’ll find comfortable rooms, complimentary bath products, and quiet sleeping areas, so you can kick back with all the basic conveniences after a long day. Plus, these properties are perfect, if you need a jumping-off point for exploring the local attractions. Several of the best hotels with 2 Stars in Depew are situated just a stone’s throw from both public transportation and the city’s main freeways. Use the travel tools at Expedia.ca to search for options near your favorite neighborhood, find a cheap deal, and book your room. 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