Depew Vacation Packages

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Your Depew Vacation

A great way to experience this interesting city is with a customized Depew vacation package. Base yourself in the neighborhood of Downtown Buffalo, which is great for nightlife, shopping and bars and pubs or choose someplace else — our packages are all about you. Make your trip to Depew even more fulfilling by going sightseeing. Walden Galleria Mall, Holiday Twin Rinks and Eastern Hills Mall are some of the popular attractions you'll want to explore. Whoever you're taking time off with and whatever your bank balance, your ultimate Depew vacation is just clicks away with Expedia.

Top Depew Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
Price was CA $1,347, price is now CA $967 per person
CA $967
per person
Mar 19 - Mar 25
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Buffalo (BUF)
8/10 Very Good! (2,709 reviews)
We really like this place. All the basics and right across from the airport. Reasonably priced.

Reviewed on Feb 12, 2026

The Eagles Nest

The Eagles Nest

4 out of 5
Price was CA $2,414, price is now CA $1,781 per person
CA $1,781
per person
May 1 - May 8
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Buffalo (BUF)
9.6/10 Exceptional! (4 reviews)
Our stay was perfect. The property manager, Jess, is very nice and was very relaxed and accommodating. The home had everything we needed and then some. Lots of space to relax, amazing views, and very peaceful.

Reviewed on Jun 3, 2025

The Richardson Hotel

The Richardson Hotel

3.5 out of 5
Elmwood Bidwell
Price was CA $1,872, price is now CA $1,403 per person
CA $1,403
per person
Mar 19 - Mar 25
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Buffalo (BUF)
9/10 Wonderful! (1,002 reviews)
Perfect in every aay

Reviewed on Feb 12, 2026

The Mansion On Delaware Ave

The Mansion On Delaware Ave

4 out of 5
Downtown Buffalo
Price was CA $1,839, price is now CA $1,418 per person
CA $1,418
per person
Mar 19 - Mar 25
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Buffalo (BUF)
9.4/10 Exceptional! (1,002 reviews)
Room upgrade. Pleasant staff.

Reviewed on Feb 3, 2026

Old Library Inn

Old Library Inn

2 out of 5
Price was CA $1,366, price is now CA $1,063 per person
CA $1,063
per person
May 1 - May 8
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Buffalo (BUF)
9.2/10 Wonderful! (19 reviews)
Beautiful home located in the next to the Old Library Restaurant. About a 30 minutes drive to Art Roscoe Park for cross country skiing.

Reviewed on Jan 7, 2026

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Depew Hotel Deals

Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
Fully refundableReserve now, pay when you stay
The price is CA $100 per night from Feb 16 to Feb 17
CA $100
CA $114 total
Feb 16 - Feb 17
includes taxes & fees
7.8/10 Good! (2,873 reviews)
T

Reviewed on Feb 6, 2026

Buffalo Airport Hotel
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
Fully refundableReserve now, pay when you stay
The price is CA $93 per night from Mar 8 to Mar 9
CA $93
CA $106 total
Mar 8 - Mar 9
includes taxes & fees
7.8/10 Good! (1,987 reviews)
Rooms were clean

Reviewed on Feb 8, 2026

Sleep Inn & Suites Buffalo Airport
Garden Place Hotel

Garden Place Hotel

3.5 out of 5
6615 Transit Road Buffalo NY
Fully refundableReserve now, pay when you stay
The price is CA $94 per night from Mar 5 to Mar 6
CA $94
CA $107 total
Mar 5 - Mar 6
includes taxes & fees
7.6/10 Good! (2,260 reviews)
Great

Reviewed on Feb 11, 2026

Garden Place Hotel
See all 881 properties in Depew
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Depew

A beautiful sunset today at ub! At least there is one perk to being stuck on campus for 12 hours! 🌅🌅🌅 #ub #universityatbuffalo #buffalo #sunset #baridpoint #oozefestpits #springsemester #academicspine #campuslife

University At Buffalo - North Campus

4/5(16 reviews)

Enjoy the collegiate vibe when you visit University At Buffalo - North Campus, during your trip to Amherst. Experience the area's great live music and acclaimed theater scene.

University At Buffalo - North Campus
NFL Salute to Service Buffalo Bills Ralph Wilson Stadium

Highmark Stadium

4/5(363 reviews)

Catch an event at Highmark Stadium during your trip to Orchard Park. Experience the area's great live music and entertainment choices.

Highmark Stadium
Downtown Buffalo NY

KeyBank Center

4/5(530 reviews)

Catch an event at KeyBank Center during your trip to Buffalo. Experience the area's entertainment choices and acclaimed theater scene.

KeyBank Center

What to do in Depew

TR is waiting to greet you!

Theodore Roosevelt Inaugural National Historic Site Admission and Guided Tour

CA $18
per adult
100% of travellers recommend
Theodore Roosevelt Inaugural National Historic Site Admission and Guided Tour
Niagara Falls Self-Guided Driving Audio Tour from Toronto

Niagara Falls Self-Guided Driving Audio Tour from Toronto

CA $23
per traveller
Niagara Falls Self-Guided Driving Audio Tour from Toronto
Buffalo Scavenger Interactive Hunt Walking Tour

Buffalo Scavenger Interactive Hunt Walking Activity

CA $48
per traveller
Buffalo Scavenger Interactive Hunt Walking Activity
See all activities in Depew

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.