Title: Depew Vacation Packages & Trips 2026 from CA $718 | Expedia.ca

[Hotels in Depew](https://expedia.ca/Depew-Hotels.d6338362.Travel-Guide-Hotels)[Vacation Rentals in Depew](https://expedia.ca/Depew-Vacation-Rentals.d6338362.Travel-Guide-VacationRentals)[Depew Car Rentals](https://expedia.ca/Car-Rentals-In-Depew.d6338362.Car-Rental-Guide)

![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium)

# Depew Vacation Packages

## Book a Hotel + Flight or Car together to unlock savings

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#### Your Depew Vacation

A great way to experience this interesting city is with a customized Depew vacation package. Base yourself in the neighborhood of Downtown Buffalo, which is great for nightlife, shopping and bars and pubs or choose someplace else — our packages are all about you. Make your trip to Depew even more fulfilling by going sightseeing. [Walden Galleria Mall](https://www.expedia.ca/Walden-Galleria-Mall-Buffalo.d6129205.Vacation-Attraction), [Holiday Twin Rinks](https://www.expedia.ca/Holiday-Twin-Rinks-Buffalo.d6207411.Vacation-Attraction) and [Eastern Hills Mall](https://www.expedia.ca/Eastern-Hills-Mall-Harris-Hill.d6129207.Vacation-Attraction) are some of the popular attractions you'll want to explore. Whoever you're taking time off with and whatever your bank balance, your ultimate Depew vacation is just clicks away with Expedia.

## Top Depew Vacation Deals

Price found within the past 48 hours. Click for updated prices.

![Buffalo Airport Hotel](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/19bd0f50_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Buffalo Airport Hotel

CA $718

per person

May 15 - May 17

found 3 hours ago

Roundtrip non-stop flight included

Tampa (TPA) to Buffalo (BUF)

8/10 Very Good! (2,928 reviews)

The rooms are well kept smd the staff were wonderful..wish the beds were bigger

Reviewed on Mar 29, 2026

![Home2 Suites by Hilton Buffalo Airport / Galleria Mall](https://images.trvl-media.com/lodging/11000000/10630000/10627700/10627666/e4026590_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Home2 Suites by Hilton Buffalo Airport / Galleria Mall

CA $1,091

per person

May 15 - May 18

found 3 hours ago

Roundtrip non-stop flight included

Tampa (TPA) to Buffalo (BUF)

9/10 Wonderful! (1,000 reviews)

Wonderful stay! Quiet, easy, good breakfast.

Reviewed on Mar 21, 2026

![Garden Place Hotel](https://images.trvl-media.com/lodging/2000000/1070000/1060800/1060721/40afc3e4_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Garden Place Hotel

CA $739

per person

May 15 - May 17

found 3 hours ago

Roundtrip non-stop flight included

Tampa (TPA) to Buffalo (BUF)

7.8/10 Good! (2,313 reviews)

The breakfast options needed to accommodate people who have gluten, and dairy intolerance. More selections of tea would’ve been nice.

Reviewed on Apr 1, 2026

![Sleep Inn & Suites Buffalo Airport](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/9d03cce3_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Sleep Inn & Suites Buffalo Airport

CA $757

per person

May 15 - May 17

found 3 hours ago

Roundtrip non-stop flight included

Tampa (TPA) to Buffalo (BUF)

8/10 Very Good! (2,019 reviews)

Great location for our college tour and Kowloon that it's across from the airport is going to be very helpful for the future. The breakfast was delicious and the parking was nice and easy.

Reviewed on Apr 2, 2026

![Hyatt Regency Buffalo / Hotel and Conference Center](https://images.trvl-media.com/lodging/1000000/30000/23200/23101/00561234_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hyatt Regency Buffalo / Hotel and Conference Center

Downtown Buffalo

CA $782

per person

May 15 - May 17

found 3 hours ago

Roundtrip non-stop flight included

Tampa (TPA) to Buffalo (BUF)

8.2/10 Very Good! (1,771 reviews)

The staff at this hotel are tremendously, friendly and helpful. We loved how they kept the granite façade of the old Genesee bank as part of their remodel. Some aspects of the hotel show their age, and signage could be more clear for things like the workout room, but overall lovely. The restaurant was great as well, and although my fingerling potatoes were a little bit too salty, otherwise the food was excellent. We will be back if we need to visit that part of Buffalo again.

Reviewed on Apr 2, 2026

## Ready to book your vacation to Depew?

Choose your dates

## Depew Hotel Deals

![Buffalo Airport Hotel](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/19bd0f50_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Buffalo Airport Hotel

4600 Genesee St Buffalo NY

Fully refundableReserve now, pay when you stay

CA $96

CA $110 total

Apr 6 - Apr 7

includes taxes & fees

8/10 Very Good! (2,922 reviews)

Couldn’t close the curtains only a sheer cover closed and it was on a ground floor. It was noisy due to other people arguing during the night. It was a great location and they offered a shuttle to the airport!! The restaurant was great.

Reviewed on Mar 31, 2026

[](https://expedia.ca/Hotel-Search?startDate=06%2F04%2F2026&endDate=07%2F04%2F2026&selected=26001&PinnedHotelID=26001&HadPinnedHotel=true&regionId=6338362)

![Holiday Inn Express Grand Island - Niagara Falls by IHG](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/3274a349_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Holiday Inn Express Grand Island - Niagara Falls by IHG

2761 Long Road Grand Island NY

Fully refundable

CA $152

CA $173 total

Apr 5 - Apr 6

includes taxes & fees

9/10 Wonderful! (1,741 reviews)

Breakfast was great! Very convenient location and quieter than being right by the falls. Room was spacious and clean, great for a family. The pool needs more regular attention as there were no towels both days and lots of stuff floating around in it (hair clumps, bandaids). We loved the rooftop bar! ...

Reviewed on Apr 3, 2026

[](https://expedia.ca/Hotel-Search?startDate=05%2F04%2F2026&endDate=06%2F04%2F2026&selected=18567279&PinnedHotelID=18567279&HadPinnedHotel=true&regionId=6338362)

![M Hotel Buffalo](https://images.trvl-media.com/lodging/1000000/20000/11300/11231/2c4d5593_y.jpg?impolicy=resizecrop&rw=340&ch=150)

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M Hotel Buffalo

2040 Walden Ave Buffalo NY

Fully refundableReserve now, pay when you stay

CA $157

CA $178 total

Apr 12 - Apr 13

includes taxes & fees

7.4/10 Good! (2,699 reviews)

They dont like to give you your downpayment back

Reviewed on Apr 3, 2026

[](https://expedia.ca/Hotel-Search?startDate=12%2F04%2F2026&endDate=13%2F04%2F2026&selected=11231&PinnedHotelID=11231&HadPinnedHotel=true&regionId=6338362)

[See all 871 properties in Depew](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=04%2F04%2F2026&endDate=05%2F04%2F2026&regionId=6338362)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

All Inclusive Vacations

[](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Beach Vacations

[](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Family Vacations

[](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Golf Vacations

[](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Luxury Vacations

[](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Romantic Vacations

[](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Ski Vacations

[](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click)

### Discover the most popular places to visit in Depew

![University At Buffalo - North Campus](https://images.trvl-media.com/place/6276889/6f4929dc-5220-42a3-b540-54ed4dcc34d4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### University At Buffalo - North Campus

4/5(17 reviews)

Enjoy the collegiate vibe when you visit University At Buffalo - North Campus, during your trip to Amherst. Experience the area's acclaimed theater scene and great live music. 

[](https://expedia.ca/University-At-Buffalo-North-Campus-Buffalo.d6175369.Vacation-Attraction)

![Highmark Stadium](https://images.trvl-media.com/place/6047844/967ffd8d-0ce5-4803-b2a8-0405cc2eb554.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Highmark Stadium

4/5(367 reviews)

Catch an event at Highmark Stadium during your trip to Orchard Park. Experience the area's entertainment choices and great live music. 

[](https://expedia.ca/Highmark-Stadium-Buffalo.d6058007.Vacation-Attraction)

![Downtown Buffalo NY](https://images.trvl-media.com/place/6064435/ddc94cc9-ad1a-4fc7-b3a1-f2ba87b4fb62.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### KeyBank Center

4/5(539 reviews)

Catch an event at KeyBank Center during your trip to Buffalo. Experience the area's great live music and entertainment choices. 

[](https://expedia.ca/KeyBank-Center-Buffalo.d6064435.Vacation-Attraction)

### What to do in Depew

![Theodore Roosevelt Inaugural National Historic Site Admission and Guided Tour](https://mediaim.expedia.com/localexpert/672820/c9cd6e97-5a62-4f94-8790-2de7c00c63ec.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Theodore Roosevelt Inaugural National Historic Site Admission and Guided Tour

CA $18

per adult

**100%** of travellers recommend

[](https://expedia.ca/things-to-do/theodore-roosevelt-inaugural-national-historic-site-admission-and-guided-tour.a672820.activity-details)

![Niagara Falls Day Tour from Toronto](https://mediaim.expedia.com/localexpert/1344001/4658fdc2-516b-4975-a716-9d41168bf57a.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Niagara Falls Day Tour from Toronto

CA $71

per adult

**96%** of travellers recommend

[](https://expedia.ca/things-to-do/niagara-falls-day-tour-from-toronto.a1344001.activity-details)

![Niagara Falls Self-Guided Driving Audio Tour from Toronto](https://mediaim.expedia.com/localexpert/49289256/11eb9a03-8a54-418e-b42b-71b7c5463267.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Niagara Falls Self-Guided Driving Audio Tour from Toronto

CA $23

per traveller

[](https://expedia.ca/things-to-do/niagara-falls-self-guided-driving-audio-tour-from-toronto.a49289256.activity-details)

[See all activities in Depew](https://expedia.ca/things-to-do/search?rid=6338362)

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