Florida Keys Adults Only Vacations

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Flight and Adults Only hotel deals in Florida Keys

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Hawks Cay Resort
Pier House Resort & Spa
Parrot Key Hotel & Villas
Cheeca Lodge & Spa
The Marker Key West Harbor Resort
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5* Adults Only holidays in Florida Keys

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Cheeca Lodge & Spa
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3 Night Adults Only holidays in Florida Keys

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Southernmost Beach Resort and Guesthouses
Pier House Resort & Spa
The Marker Key West Harbor Resort
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4 Night Adults Only holidays in Florida Keys

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Parrot Key Hotel & Villas
Pier House Resort & Spa
Cheeca Lodge & Spa
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Adults Only Hotels in Florida Keys

The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

3 out of 5
525 United Street Key West FL
  • 36 min drive from Florida Keys Beaches
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.4/10 Very good! (1,398 reviews)
"We were told we would have housecleaning every other day, we did not get it even one day. We had to keep going to the desk to get new towels, toilet paper soap. We even hung the sign on the door stating that we wanted it cleaned, and it was never cleaned. They messed up our parking and when we returned ..."

Reviewed on Jul 3, 2026

The Southernmost Inn - Adults Only
Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only

3.5 out of 5
819 Simonton Street Key West FL
  • 36 min drive from Florida Keys Beaches
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, parking (surcharge), and a garden. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (1,000 reviews)
"Great boutique hotel close to every thing. Very impressed with the king suite it was so large and overlooked the pool. Nicely updated. Air conditioning was ice cold worked very well. Great happy hour with wine cheese and crackers. The girl at the front office goes out of her way to make sure you ..."

Reviewed on Jul 1, 2026

Paradise Inn Key West - Adults Only
Heron House - Adult Only

Heron House - Adult Only

3.5 out of 5
512 Simonton St Key West FL
  • 36 min drive from Florida Keys Beaches
Stay at this B&B in Key West. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the pool in our reviews. Popular attractions ...
9.2/10 Wonderful! (1,157 reviews)
"AMAZING place. Super well taken care of, roo.s are spacious and beautiful A(I stayed in room 10). The staff was super helpful and Greg was a Great. Just a few blocks from the Walgreens on Duval but way from all the craziness. Adults only makes a difference for sure! Will definetly return"

Reviewed on Jun 29, 2026

Heron House - Adult Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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