South Carolina Midlands Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

    deals illustration

    Better together

    Save up to CA $1,096 when you book a flight and hotel together*
    stays illustration

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    luggage illustration

    Rest easy

    Plan, book, and manage your trip all in one place

Your South Carolina Midlands Vacation

Whether you're heading to South Carolina Midlands for its rich history, spectacular views or something else entirely, this destination is one you won't forget in a hurry. Create your ultimate break with one of our South Carolina Midlands vacation packages. With so much to see and do on a trip to South Carolina Midlands, it can be difficult to know where to start. Kick off your travels in Columbia at Riverbanks Zoo and Garden and Williams Brice Stadium — two popular attractions here. Another city worthy of a spot on your itinerary is Florence. Don't miss Magnolia Mall and Mcleod Regional Medical Centre. Expedia has flights, hotels, car rentals and more to help you create your very own customized South Carolina Midlands vacation today.

Top South Carolina Midlands Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Sands Ocean Club Resort

Sands Ocean Club Resort

3 out of 5
Save 100% on your flight
per person
Aug 22 - Aug 25
found 14 hours ago
Roundtrip flight included
Detroit (DTW) to Myrtle Beach (MYR)
7.4/10 Good! (2,291 reviews)
Room at check-in was

Reviewed on Jul. 15, 2025

Westgate Myrtle Beach Oceanfront Resort

Westgate Myrtle Beach Oceanfront Resort

3.5 out of 5
per person
Aug 22 - Aug 25
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Myrtle Beach (MYR)
8/10 Very Good! (1,016 reviews)
I liked how they text you updates about the events going on in the hotel and you can text them if you need extra towels/shampoo/soap/etc. That was very convenient for us. Friendly staff and clean lobby/room.

Reviewed on Jul. 12, 2025

Marina Inn At Grande Dunes

Marina Inn At Grande Dunes

4.5 out of 5
Save 100% on your flight
per person
Aug 22 - Aug 25
found 14 hours ago
Roundtrip flight included
Detroit (DTW) to Myrtle Beach (MYR)
9.2/10 Wonderful! (1,712 reviews)
Always a comfortable stay and friendly service and staff.

Reviewed on Jul. 9, 2025

Grand Atlantic Ocean Resort

Grand Atlantic Ocean Resort

3.5 out of 5
Save 100% on your flight
per person
Aug 22 - Aug 25
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Myrtle Beach (MYR)
8.6/10 Excellent! (1,004 reviews)
Excellent! Will be back!

Reviewed on Jul. 15, 2025

Hampton Inn & Suites Myrtle Beach/Oceanfront

Hampton Inn & Suites Myrtle Beach/Oceanfront

3 out of 5
Save 100% on your flight
per person
Aug 22 - Aug 25
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Myrtle Beach (MYR)
8.4/10 Very Good! (1,027 reviews)
Very friendly staff. Clean hotel overall, clean and nice hotel room. Great spot for adults and kids

Reviewed on Jul. 15, 2025

Where to stay in South Carolina Midlands

Find the best South Carolina Midlands areas and neighborhoods for the activities you enjoy most. Learn more about South Carolina Midlands
Columbia

Downtown Columbia

2 out of top 10 points of interest in this area

Travelers come to Downtown Columbia for its lively bars, and you can see top attractions like South Carolina State House and Columbia Museum of Art while you're in town.

Find hotels in Downtown Columbia

Ready to book your vacation to South Carolina Midlands?

 

Choose your dates

South Carolina Midlands Hotel Deals

Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street, Building 2, Columbia, SC
Fully refundableReserve now, pay when you stay
The price is CA $139 per night from Jul 27 to Jul 28
CA $139
CA $155 total
Jul 27 - Jul 28
includes taxes & fees
9.2/10 Wonderful! (173 reviews)
"We enjoyed our stay, the rooms were clean, staff were friendly and helpful. The breakfast was great. The only complaint would be having to pay for parking each day of the stay. One would assume parking would be included with the price of the stay?"

Reviewed on Jul. 14, 2025

Tru By Hilton Columbia Downtown
Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr, Columbia, SC
Fully refundableReserve now, pay when you stay
The price is CA $115 per night from Jul 27 to Jul 28
CA $115
CA $129 total
Jul 27 - Jul 28
includes taxes & fees
8.8/10 Excellent! (1,623 reviews)
"This was a very attractive and clean facility and with a lovely staff."

Reviewed on Jul. 10, 2025

Hilton Garden Inn Columbia/Harbison
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd, Columbia, SC
Fully refundableReserve now, pay when you stay
The price is CA $115 per night from Jul 20 to Jul 21
CA $115
CA $129 total
Jul 20 - Jul 21
includes taxes & fees
7.4/10 Good! (1,017 reviews)
"The breakfast was good and the staff were all very kind and helpful."

Reviewed on Jul. 12, 2025

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
See all 2,957 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Discover the most popular places to visit in South Carolina Midlands

Carowinds Theme Park

Carowinds Theme Park

Choose from 13 roller coasters, chase your friends in a bumper car, enjoy the water slides and beaches of Boomerang Bay, and walk with dinosaurs.

Carowinds Theme Park
Riverbanks Zoo and Garden

Riverbanks Zoo and Garden

Why not meet the animals who call Riverbanks Zoo and Garden home during your trip to Columbia? You can attend a sporting event while in the area.

Riverbanks Zoo and Garden
Congaree National Park

Congaree National Park

While protecting southern hardwood forest for the enjoyment of future generations, this park also offers hiking, canoeing and interesting ranger-led activities.

Congaree National Park

Frequently asked questions

How much does a South Carolina Midlands vacation package cost?
From as little as CA $374. Yes, you read that correctly. Our South Carolina Midlands vacation packages are the easiest way to stretch your budget further. Bundle your preferred hotels, flights and rental car and get out and see this vibrant destination.
How do I get a cheap travel package to South Carolina Midlands?
Track down flights that suit your schedule, add a hotel to your booking and see how much you save with a South Carolina Midlands vacation package. It's that simple! From flights and hotels to tours and rental cars, Expedia makes traveling cheap and easy. And with over 550 airlines and 1,000,000 hotels throughout the world to select from, you won't be short of choice.
Where should I stay in South Carolina Midlands?
If you're eager to explore University of South Carolina and South Carolina State House, the city of Columbia is the destination for you.
What are the top hotels in South Carolina Midlands?
Take a look at Country Inn & Suites by Radisson, Columbia, SC and Graduate Columbia, S.C.. They're top picks for many travelers to Columbia. If North Augusta features in your travel plans, Holiday Inn Express & Suites Aiken, an IHG Hotel and Fairfield Inn & Suites by Marriott Aiken are both welcoming options.
How far in advance should I book my South Carolina Midlands vacation?
Reward yourself with the widest variety and the lowest prices by booking your South Carolina Midlands adventure nice and early. Air carriers usually publish tickets around 12 months before departure, so start your planning ASAP. Having said that, Expedia is constantly working to give you the best bargains around, so it's always a good time to book your dream vacation!
What does an Expedia South Carolina Midlands travel package include?
Car rentals, flights and hotels --- we bring you the best deals. All you'll have to do is pick and choose your ideal combination. After you've made your booking, you can add on the exciting stuff like activities and tours. Our travel packages make it simple to craft an exciting South Carolina Midlands escape.
What should I know before booking a South Carolina Midlands travel package?
Locking in all the parts of your vacation together is an excellent way to save. Bundle car rentals, airfares and hotels into a handy little package. But it's not just hotels. Expedia features all types of properties, including vacation rentals such as mountain cabins and city apartments. Your choices are almost endless!
Can I choose my airline with a South Carolina Midlands Expedia vacation package?
Expedia has access to more than 550 airline partners worldwide, so you sure can! Just select your preferred air carrier and put together your ideal South Carolina Midlands vacation.
If I'm not able to travel, can I cancel my South Carolina Midlands vacation package?
Yes, you can. We realize life happens, so we're here to help if you have to make changes to your South Carolina Midlands vacation package. You may be able to change or cancel your itinerary at no cost if you've booked within 24 hours. Your airline, hotel or car rental company may impose a fee if you booked more than 24 hours ago. Take a look at our Customer Service Portal for further information. Also, check your itinerary for the nitty-gritty on change fees.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.