Title: South Carolina Midlands Vacation Rentals from CA $165: Short-Term Rentals for 2025 | Expedia.ca [South Carolina Midlands Travel Guide](https://expedia.ca/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Flights to South Carolina Midlands](https://expedia.ca/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[South Carolina Midlands Car Rentals](https://expedia.ca/Car-Rentals-In-South-Carolina-Midlands.d6057938.Car-Rental-Guide)[South Carolina Midlands Vacation Packages](https://expedia.ca/South-Carolina-Midlands.d6057938.Destination-Travel-Guides) ![South Carolina State House](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/183000/183997-State-House.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # South Carolina Midlands Vacation Rentals ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Vacation Rentals in South Carolina Midlands ![Terrace/patio](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/b733a543.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/be58ae40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/cfa3fc89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/917b8b10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### stayAPT Suites Columbia-Irmo Harbison Irmo 8.6/10 Excellent (309) "This property was a great stay with our fur babies. I love the spacious room and of course being a pet friendly property. " CA $161 CA $175 total includes taxes & fees Sep 25 - Sep 26 [](https://www.expedia.ca/Irmo-Hotels-StayAPT-Suites-Columbia-Irmo-Harbison.h71943321.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/46000000/45150000/45148000/45147909/afc287a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Loft 007 Ft. on HGTV | Terrace/patio](https://images.trvl-media.com/lodging/46000000/45150000/45148000/45147909/0841e785.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/46000000/45150000/45148000/45147909/376ea7b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Loft 007 Ft. on HGTV](https://images.trvl-media.com/lodging/46000000/45150000/45148000/45147909/91af7762.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Hangar Lofts Hotel Rosewood 8.6/10 Excellent (63) "Enjoyed this property. Will stay here every time I book in Columbia. And for my Travel Clients. " CA $169 CA $190 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Columbia-Hotels-The-Hangar-Lofts-Hotel.h45147909.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/72000000/71950000/71945700/71945688/w7294h4496x8y0-e7e0c635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71945700/71945688/5ac04ce0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/72000000/71950000/71945700/71945688/795f1e13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/72000000/71950000/71945700/71945688/d6e5ecdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### stayAPT Suites Rock Hill Rock Hill 8.4/10 Very good (185) "This was such an amazing stay ! Very peaceful atmosphere and great employees!" CA $148 CA $165 total includes taxes & fees Sep 25 - Sep 26 [](https://www.expedia.ca/Rock-Hill-Hotels-StayAPT-Suites-Rock-Hill.h71945688.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/27000000/26930000/26925700/26925650/b1fcd805.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/27000000/26930000/26925700/26925650/1c0b7271.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/27000000/26930000/26925700/26925650/2df875b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26930000/26925700/26925650/845b6468.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful & Spacious with Hot Tub, Game Room & More. Large Yard Near the Dam! Lexington 9.8/10 Exceptional (132) "Great stay, every thing was easy, clean and as advertised! We would stay here again!" [](https://www.expedia.ca/Columbia-Hotels-Lake-Murray-Paradise-Lake-Front-Upstairs-Home-W-Peninsula-Lake-Views.h26925650.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/64000000/63170000/63163900/63163810/aa493255.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/64000000/63170000/63163900/63163810/850d0032.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/64000000/63170000/63163900/63163810/5dfeecd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/64000000/63170000/63163900/63163810/b5f90dbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sunset Gem private dock & boat ramp on Lake Murray Prosperity 9.6/10 Exceptional (92) "Great place to stay" [](https://www.expedia.ca/Prosperity-Hotels-Sunset-Gem-Private-Dock-Boat-Ramp-On-Lake-Murray.h63163810.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/25000000/24260000/24257000/24256959/d11c2084.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24260000/24257000/24256959/8cdaa2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/25000000/24260000/24257000/24256959/ce07daaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books, video library](https://images.trvl-media.com/lodging/25000000/24260000/24257000/24256959/db2f6213.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Replica home from Jack Nicholson movie - 'Something's Gotta Give' Chapin 10/10 Exceptional (137) "We had a relaxing wonderful time..the owner was very nice and helpful ..always responded promptly." [](https://www.expedia.ca/Chapin-Hotels-Replica-Home-From-Jack-Nicholson-Movie-Somethings-Gotta-Give.h24256959.Hotel-Information) ![Beach nearby, sun loungers, beach towels](https://images.trvl-media.com/lodging/77000000/76320000/76317400/76317327/3fe1338e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/77000000/76320000/76317400/76317327/38635a45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/77000000/76320000/76317400/76317327/01ea4499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/77000000/76320000/76317400/76317327/a1639ff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Exclusive Peninsula Retreat on Lake Murray – Beach, Fire Pit & Stunning Sunsets Chapin 10/10 Exceptional (55) "Second year that out of town family stayed at property for a family reunion. Was very enjoyable and great for the lake access. Will definitely go back and recommend to others. " [](https://www.expedia.ca/Chapin-Hotels-Mind-Blowing-Sunsets-On-A-Gated-Peninsula-Property-With-A-White-Sand-Beach.h76317327.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112570000/112562700/112562606/56893853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/113000000/112570000/112562700/112562606/78bc4929.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/113000000/112570000/112562700/112562606/d02f516e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112570000/112562700/112562606/d9f603fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Romantic bungalow on Lake Murray w/cold plunge/hot tub/sauna, gym & dock gazebo Lexington 10/10 Exceptional (11) "Took the Mrs fishing for a weekend away. Kent was very professional and made all accommodations perfect. Would definitely recommend and look forward to coming back. " [](https://www.expedia.ca/Lexington-Hotels-Romantic-Bungalow-On-Lake-Murray-Wcold-Plungehot-Tubsauna.h112562606.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/bfd80ad8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/cf50a6e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV, DVD player](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/d97d64ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/3622349b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Vacation Resorts Lake Marion Santee 9.2/10 Wonderful (20) "Friendly staff. Excellent accomodations. Peaceful and beautiful vacation." [](https://www.expedia.ca/Orangeburg-Hotels-Wyndham-Vacation-Resorts-Lake-Marion.h43992569.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/104000000/103460000/103459000/103458981/54575a7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103460000/103459000/103458981/2ab091e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/104000000/103460000/103459000/103458981/00fad188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/104000000/103460000/103459000/103458981/9c00edd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quant Downtown Columbia Apartment Downtown Columbia 10/10 Exceptional (2) "Nice stay in center of five points close yo everything " CA $107 CA $267 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Columbia-Hotels-Quant-Downtown-Columbia-Apartment.h103458981.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/45000000/44330000/44321400/44321347/d5e8aaaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/45000000/44330000/44321400/44321347/3cb780fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/45000000/44330000/44321400/44321347/47aa7ff5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/45000000/44330000/44321400/44321347/b87255a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Close to Ft. Jackson & USC Columbia 6.0/10 (2) "The host did not ever send check in instructions, and did not respond to phone calls or messages from me or VRBO. This left us stranded in Columbia without a place to stay. After 2 days of no communication and no way of getting in to the property, the host ended up cancelling our stay and cited "guest minimum age" as the reason for him cancelling. All individuals staying at the property were 30 years or older. The host never reached out directly to us at all. DO NOT BOOK THIS PLACE." CA $173 CA $279 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Columbia-Hotels-Close-To-Ft-Jackson-USC.h44321347.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/95000000/94790000/94783400/94783316/9046973f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/95000000/94790000/94783400/94783316/75879089.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/95000000/94790000/94783400/94783316/05a68624.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/95000000/94790000/94783400/94783316/e4df59bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stylish suite DOWNTOWN with FREE parking and a GYM Downtown Columbia 9.8/10 Exceptional (32) "Good location, excellent communication with our host and met or exceeded expectations " CA $106 CA $243 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Columbia-Hotels-Stylish-Suite-DOWNTOWN-With-FREE-Parking-And-A-GYM.h94783316.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/92000000/91040000/91039900/91039871/w1024h680x0y3-9269f16b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91040000/91039900/91039871/w1024h678x0y3-efa216bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, cookware/dishes/utensils](https://images.trvl-media.com/lodging/92000000/91040000/91039900/91039871/50215f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91040000/91039900/91039871/b59bdaca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NoMa Green House Columbia 9.8/10 Exceptional (64) "Great property! Excellently maintained and nicely decorated. " CA $149 CA $368 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Columbia-Hotels-NoMa-Green-House.h91039871.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100710000/100706200/100706194/87150793.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, travel crib, WiFi](https://images.trvl-media.com/lodging/101000000/100710000/100706200/100706194/8e7a6fa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/101000000/100710000/100706200/100706194/bd8fa2a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/101000000/100710000/100706200/100706194/81ecd585.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2 Bdrm Condo w/in 10 min from USC, Downtown Columbia, Ft Jackson, VA hospital Rosewood 9.4/10 Exceptional (41) "Host was friendly and it was an easy check in!" [](https://www.expedia.ca/Columbia-Hotels-2-Bdrm-Condo-Win-10-Min-From-USC.h100706194.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/31000000/30230000/30224400/30224312/7ef3ac4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/31000000/30230000/30224400/30224312/8a16d457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/31000000/30230000/30224400/30224312/a5e2fb13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/31000000/30230000/30224400/30224312/dbe17bc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Archie's Lake Daze Cottage - No Pets Manning 10/10 Exceptional (80) "Have stayed here a few times never disappoints" [](https://www.expedia.ca/Sumter-Hotels-Archies-Lake-Daze-Cottage.h30224312.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/98000000/97410000/97408700/97408699/96d90c64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/98000000/97410000/97408700/97408699/38b3a2ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/98000000/97410000/97408700/97408699/5f066aad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/98000000/97410000/97408700/97408699/2b257aba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rustic Country Cottage Near Lake Murray -Just 1 hour from The Masters! Columbia 10/10 Exceptional (25) "We enjoyed having games to play as a family in our down time. " [](https://www.expedia.ca/Columbia-Hotels-Country-Cottage-Near-Lake-Murray-On-2-Acres-With-Firepit-And-Chicken-Coop.h97408699.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/93000000/92180000/92179900/92179823/0cf39ca3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/93000000/92180000/92179900/92179823/344f2c74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92180000/92179900/92179823/006e3fde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/93000000/92180000/92179900/92179823/00193b79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### This Old House By The Park Columbia 10/10 Exceptional (4) "Nice spacious home, very comfortable furniture and the host was very accommodating. We will stay again if ever in the area. " [](https://www.expedia.ca/Columbia-Hotels-This-Old-House-By-The-Park.h92179823.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/110000000/109040000/109033200/109033115/d7e31523.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109040000/109033200/109033115/8d584d27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/110000000/109040000/109033200/109033115/3a1c4e15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/110000000/109040000/109033200/109033115/67c212f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 2-Bedroom, 1-Bath bungalow Columbia 9.8/10 Exceptional (26) "I come into town every month or so for work. This is a perfect location just for me - the place is spotless and quiet, easy access to work. " [](https://www.expedia.ca/Columbia-Hotels-Charming-2-Bedroom.h109033115.Hotel-Information) ![TV, fireplace, DVD player, foosball](https://images.trvl-media.com/lodging/23000000/22540000/22537400/22537351/da60aa89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22540000/22537400/22537351/f5e2118a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, DVD player, foosball](https://images.trvl-media.com/lodging/23000000/22540000/22537400/22537351/55278e3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/23000000/22540000/22537400/22537351/360b0a95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful 4 bedroom Lakehouse on a deep water cove on Lake Greenwood. Greenwood 10/10 Exceptional (189) "Enjoyed our stay. Nice house on nice spot on lake. " [](https://www.expedia.ca/Greenwood-Hotels-Beautiful-4-Bedroom-Lakehouse-On-A-Deep-Water-Cove-On-Lake-Greenwood.h22537351.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/90000000/89330000/89325600/89325563/b7da2b79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89330000/89325600/89325563/4b7cb62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89330000/89325600/89325563/c87ec78f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89330000/89325600/89325563/683c7a80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy Manning 9.8/10 Exceptional (90) "Perfect for a big family. Loved the house and the location. Beautiful lake. A very happy stay. " [](https://www.expedia.ca/Manning-Hotels-The-Big-Red-House.h89325563.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-08&endDate=2025-10-09®ionId=6057938&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Vacation-Rentals.d6057938.Travel-Guide-VacationRentals)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Vacation-Rentals.d6057938.Travel-Guide-VacationRentals) ## Top South Carolina Midlands Hotel Reviews ![ La Quinta Inn by Wyndham Columbia NE/Fort Jackson](//images.trvl-media.com/lodging/1000000/50000/43600/43541/ebebcc50_y.jpg) ### La Quinta Inn by Wyndham Columbia NE/Fort Jackson 10/10 Excellent "Everything was good. " [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia-NE-Fort-Jackson.h43541.Hotel-Information) ![Sleep Inn Columbia](//images.trvl-media.com/lodging/1000000/130000/127000/126908/de238acf_y.jpg) ### Sleep Inn Columbia 10/10 Excellent "Clean reasonabke priced. Staff was helpful and nice." [](https://expedia.ca/Columbia-Hotels-Sleep-Inn-At-Bush-River-Road.h126908.Hotel-Information) ![Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG](//images.trvl-media.com/lodging/1000000/690000/688700/688607/805d082b_y.jpg) ### Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG 10/10 Excellent "It seemed nice. Was very comfortable. " [](https://expedia.ca/Columbia-Hotels-Holiday-Inn-Express-Suites-Columbia-I-26-Harbison-Blvd.h688607.Hotel-Information) ![Park Inn by Radisson Florence, SC](//images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg) ### Park Inn by Radisson Florence, SC 10/10 Excellent "Excellent stay at this property. Every employee was welcoming and helpful. My special requests were accomodated. The room was comfortable and quiet. Breakfast was good. " [](https://expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Clarion Pointe Near University](//images.trvl-media.com/lodging/1000000/30000/22100/22006/69d65d2e_y.jpg) ### Clarion Pointe Near University 10/10 Excellent "Staff is great property is well managed" [](https://expedia.ca/Rock-Hill-Hotels-Clarion-Pointe-Rock-Hill-Near-Training-Camp.h22006.Hotel-Information) ![Tru By Hilton Columbia Downtown](//images.trvl-media.com/lodging/111000000/110650000/110648500/110648494/w3840h2557x0y3-1e9d91e1_y.jpg) ### Tru By Hilton Columbia Downtown 10/10 Excellent "Close to University, staff is lovely, room is beautiful and clean" [](https://expedia.ca/Columbia-Hotels-Tru-By-Hilton-Columbia-Downtown.h110648494.Hotel-Information) ![Super 8 by Wyndham Harbison/Parkridge Hospital](//images.trvl-media.com/lodging/1000000/530000/523100/523046/42de4f92_y.jpg) ### Super 8 by Wyndham Harbison/Parkridge Hospital 10/10 Excellent "The staff was very friendly. Had a great week with my family." [](https://expedia.ca/Columbia-Hotels-Super-8-By-Wyndham-HarbisonParkridge-Hospital.h523046.Hotel-Information) ![Hilton Garden Inn Columbia/Harbison](//images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9_y.jpg) ### Hilton Garden Inn Columbia/Harbison 10/10 Excellent "Everyone was so nice and helpful" [](https://expedia.ca/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information) ![La Quinta Inn by Wyndham Columbia SE / Fort Jackson](//images.trvl-media.com/lodging/1000000/10000/5100/5038/e9b1ea9e_y.jpg) ### La Quinta Inn by Wyndham Columbia SE / Fort Jackson 10/10 Excellent "Staff was very friendly and helpful" [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information) ## Find out more about South Carolina Midlands **Everything you need to know about** **South Carolina Midlands** **vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the South Carolina Midlands vacation rental for you. At Expedia, you can take your pick from [private vacation homes](https://www.expedia.ca/aa/PrivateVacationHomes), [apartments](https://www.expedia.ca/aa/Apartments), cottages, [cabins](https://www.expedia.ca/aa/Cabins), villas... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect South Carolina Midlands vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.  **South Carolina Midlands vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in South Carolina Midlands. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in .  Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A South Carolina Midlands vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of South Carolina Midlands vacation rentals we have selected for you start as low as CA $165 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on South Carolina Midlands rentals** At Expedia, we put the best South Carolina Midlands vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.  To find some top South Carolina Midlands rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream South Carolina Midlands vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around South Carolina Midlands. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.  ## Explore a world of travel with Expedia - Trending destinations on Expedia.ca - All accommodation types in South Carolina Midlands ### Trending destinations on Expedia.ca - [Canmore Vacation Rentals](https://www.expedia.ca/Canmore-Vacation-Rentals.d10131.Travel-Guide-VacationRentals) - [Maui Vacation Rentals](https://www.expedia.ca/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals) - [Kelowna Vacation Rentals](https://www.expedia.ca/Kelowna-Vacation-Rentals.d3997.Travel-Guide-VacationRentals) - [Whistler Vacation Rentals](https://www.expedia.ca/Whistler-Vacation-Rentals.d4115.Travel-Guide-VacationRentals) - [Florida Vacation Rentals](https://www.expedia.ca/Destinations-In-Florida.d211.Vacation-Rental-Destinations) - [Victoria Vacation Rentals](https://www.expedia.ca/Victoria-Vacation-Rentals.d4138.Travel-Guide-VacationRentals) - 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[Visit Cherry Grove Beach](https://expedia.ca/North-Myrtle-Beach-Cherry-Grove-Beach.dx553248621561867974) - [Visit Whidbey Island](https://expedia.ca/Whidbey-Island.dx500782) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAMgAQAAAADzCzvFAAAFAElEQVR4Xu3cPXLjOBBAYagcONwj6Cg6GnU0HYVH2FCBy9jpH6BBkFRVB7OB9F4iqgXgU0bTnt1S/4fKPPgbgaQCSQWSCiQVSCqQVCCpQFKBpAJJBZIKJBVIKpBUIKlAUoGkAkkFkgokFUgqkFQgqUBSgaQCSQWSCiTVgPyUqatM7+Wf+uuDYdWl1kdb9We01H99TW+Jk0FAQECsq0xBQEAmZIl31ZFq22/1KS/9REW+bUGMetuzQEBAQCSQGPVAQHyt9m3I8YkH9VWab+yBTIGAFBAQD2QKxNeWP4/YffG+Wld5AQEpIG3xPhAJxIYgtngfiORIld9wazdbs5avvv4xrKogICAgHkgFAdEySNS3V/kDs/6GWxBNb/uOFHMV6YGAVBCQ+QMQCwSkzsi2q63V7X7iq9HUEieDHIymljgZ5GA0tcTJIAejqSVOBjkYTS1xMsjBaGqJk0EORlNLnDwgx91ty02u+4ljq93jXwUSgYyBjIFEIGMgY++M/MqZ33Jike0dedojto8uslRH256y+DoNd6tAPBCQaLcKxAMBiXar3gTx7Q9B/MRqD883uTKvzI/YunH8T5B9Yw8EpILoRhAQEBBrQH5kRayV7f48/TsjMZITI/1JwJNVHggISF8PAlJAQE6Rbxn0e/xFXnz7OKri6lcZN/ZVPRAQkHkjiLyAyKK4BJk3fhaixYl3236Tkbian6hdZf3drn2VnrW0c0FAQEAqCAjIGVJt7UV+d136iYt94qNt7k5fRfrarAPRQEBAQEBAvGGj3uMV0e1y9x5Hsthaqv7N2R/EtbsNbn2wCUQDAbHBrQ82gWggIDa49cGmT0DiA7t7a6ut0VWPhuhGfTZ/tI+LfJUeCAgICMijfVxApLUdAVLlVj0+KV9tqDd0Hcm7+CqO6CO2ryoyko0/ICAgIBpIWwUCcoLoB37iWCDSl3wVTVf1Ex0p9lW2gbRVICCtzWYNpK0CAWltNmufgPiJjvjde2zrbn840LN6IAUEBEQ+se0gICATIunDc7Fbdax9CFLr2tyLb5LRQbqqBwICEkdHICAVBKS3u1X7Pb6I60gkq7y2cb8KpAUCAgICAiINyI+d9OIeL2Pd7q6OrjK420BH+0DaiSAgbbQPpJ0IAtJG+94VWeJd295PLOKu8rLYyH8S0A5HcVRcgpyO4qi4BDkdxVFxCXI6iqPiEuR0FEfFJcjpKI6KS5DTURwVl4rEWp/2Px3vVo33eM9/ErhOXxgEBKR9UkFAQHarQOa+BNGn7iqunyijVq3r8E7dfSAtkCGQKZAWyBDI1FsiB6mr/9cORfqJMRL3p9/QH4as8u2GQNoIZAgEBEQCaaPPRfTEMd8e/5ba5+Mjtm/0VY+2cRuIBjIGAuKLLRAJ5HORJd7V/Vod+Sr9pbfe493VHCkv7/FLvAMB2YxAPBAQCeSjkLh7H5zYl/qq42pdQUAkkBeBgHggL/p4pOWjnq+q8jdn/1dgT5nPG0FAQOQTkP1aEBCQI6Tadu1p93hH2q+z+27tIRtrXeWTJcYgICBDICAgIDskcqSae2vjl4h+FW+JIQgIyCYQkBiCgPj26CrTu13fbPvVVunztP8k0DtzQUBAIpAKsg0E5O8FkgokFUgqkFQgqUBSgaQCSQWSCiQVSCqQVCCpQFKBpAJJBZIKJBVIKpBUIKlAUoGkAkkFkgokFUgqkFTvg/wHPf9fIoF+62YAAAAASUVORK5CYII=)