A coastal cityscape with a prominent Ferris wheel, beachfront, and high-rise buildings.

Lakefront Hotels & Resorts in South Carolina

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Top Cities in South Carolina

A beach with people, a large Ferris wheel, and tall buildings in the background.
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Myrtle Beach

Myrtle Beach

Check availability on South Carolina Lake Hotels

Our top choices for South Carolina hotels on the lake

A dock with a boat and a covered area, surrounded by trees and a pathway.

1. 😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks

😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks
Seneca
10.0 out of 10, Exceptional, (254 reviews)
"The place was very nice and clean, we had a great time."
United States
Dee H.
😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks
A golf course with a water body, trees, and a distant view of a bridge.

2. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.4 out of 10, Exceptional, (1,012 reviews)
"Great property!"
United States
Lilllian
The price is CA $198
CA $220 total
includes taxes & fees
Dec 2 - Dec 3
Clemson University's James F. Martin Inn
An outdoor patio area with wicker furniture, a stone fireplace, and a flat-screen TV mounted above.

3. Hampton Inn Columbia I-26/Harbison Blvd.

Hampton Inn Columbia I-26/Harbison Blvd.
2.5 star property
St. Andrews
9.2 out of 10, Wonderful, (1,001 reviews)
"Will stay again."
United States
Robert
The price is CA $141
CA $158 total
includes taxes & fees
Dec 13 - Dec 14
Hampton Inn Columbia I-26/Harbison Blvd.
A covered outdoor seating area with chairs and tables, overlooking a body of water and surrounded by greenery.

4. Charleston Kiawah Island/Andell Inn

Charleston Kiawah Island/Andell Inn
3.5 star property
Kiawah Island
9.6 out of 10, Exceptional, (578 reviews)
"Beautiful property!"
United States
Sandi
The price is CA $426
CA $506 total
includes taxes & fees
Dec 13 - Dec 14
Charleston Kiawah Island/Andell Inn
A spacious kitchen with wooden cabinets, a dishwasher, and a large island.

5. Beautiful Home, Close to Beach, Lagoon, Fantastic Pool!

Beautiful Home, Close to Beach, Lagoon, Fantastic Pool!
Mid Island
9.2 out of 10, Wonderful, (77 reviews)
"The location is perfect, the house is very ample and comfortable, the pool great. The only point to remark is that it needs a furniture and appliances upgrade. We had a great time."
United States
Fernando M.
Beautiful Home, Close to Beach, Lagoon, Fantastic Pool!
A spacious living room with a large window, a dining area, and a kitchen with a built-in oven.

6. January 2 to March 20, 2027 Just Opened Due to Repeat Guest's Emergency Cancel!!

January 2 to March 20, 2027 Just Opened Due to Repeat Guest's Emergency Cancel!!
Mid Island
10.0 out of 10, Exceptional, (293 reviews)
"We had a great stay in Palmetto Dunes. The Villa was beautiful! It was also very clean. The location was perfect. The hosts was very easy to work with. We hope to be back!"
United States
Rachel A.
January 2 to March 20, 2027 Just Opened Due to Repeat Guest's Emergency Cancel!!
A cabin with a porch, surrounded by trees and a body of water.

7. Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (668 reviews)
"Everything was adequate or good."
United States
Sharyn
The price is CA $90
CA $100 total
includes taxes & fees
Nov 17 - Nov 18
Red Roof Inn Santee
A hotel room with a bed, a desk, a television, and a mirror.

8. River Front Inn

River Front Inn
2.5 star property
Conway
6.8 out of 10, (205 reviews)
"Staff was very friendly and helpful. Would stay here again."
United States
Jean
River Front Inn
A modern hotel room with a large bed, bedside tables, a nightstand, and a bathroom visible through an open door.

9. Motel 6 West Columbia, SC - Airport

Motel 6 West Columbia, SC - Airport
2.0 star property
West Columbia
7.6 out of 10, Good, (737 reviews)
"Location was good for access to interstate"
United States
Christopher
The price is CA $93
CA $100 total
includes taxes & fees
Nov 15 - Nov 16
Motel 6 West Columbia, SC - Airport
A covered outdoor dining area with a view of the sea, featuring wicker chairs, a glass table, and a vase of pink tulips.

10. The Cottages on Charleston Harbor

The Cottages on Charleston Harbor
4.0 star property
Mount Pleasant
9.4 out of 10, Exceptional, (20 reviews)
"Beautiful location and unit. We thoroughly enjoyed our stay!"
United States
Diana
The Cottages on Charleston Harbor
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South Carolina Hotel Reviews

Palmera Inn and Suites

Palmera Inn and Suites

10/10 Excellent
"Loved having the kitchen in the room. Nice size refrigerator for a hotel room. Very pleased with the hotel."
Heidi 2-night trip
Posted less than an hour ago
Palmera Inn and Suites

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Frequently asked questions

How much do lakeside hotels in South Carolina cost?
Lakeside hotels in South Carolina range between CA $158 and CA $506 per night. This means you can look forward to a getaway close to the water at a price that won't break the bank. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best lakeside hotels in South Carolina?
South Carolina offers multiple lakeside hotels with a total average guest review rating of 9.5. Planning a getaway to Myrtle Beach? Stay at Hampton Inn & Suites Myrtle Beach/Oceanfront, a popular 3-star option with a terrace and hypo-allergenic bedding. Another recommended lake hotel is Hampton Inn Myrtle Beach Broadway at the Beach. It has a 2.5-star rating and amenities including complimentary use of a nearby fitness centre and a swimming pool.
How many lakeside hotels are there in South Carolina?
Explore our 147 hotels near lakes in South Carolina and then book your favorite. Whether you're embarking on a family escape or jet-setting with friends, your perfect lakeside stay is just a keystroke away with Expedia.
Are there any family-friendly lakeside hotels in South Carolina?
You'll discover some wonderful family-friendly hotels near a lake in South Carolina. If you're vacationing in Myrtle Beach, take a look at Hampton Inn & Suites Myrtle Beach/Oceanfront. With amenities such as a children's pool and a playground, your entire crew will enjoy chilling out at this 3-star property. Kingston Plantation Condos is another top pick for families seeking a lakeside retreat in Myrtle Beach. This 3.5-star option offers a waterslide, a playground and more. You'll discover lots of fabulous things to do with your team in Myrtle Beach. Myrtle Beach Boardwalk and Broadway at the Beach offer a fantastic day out.
Why book your lakeside hotel in South Carolina with Expedia?
Expedia has the best deals on lakeside hotels in South Carolina. But our fabulous prices are just the start. You'll discover plenty of hotels to pick from and clever search filters that make it a breeze to find your ideal getaway.
How can I find cheap lakeside hotels in South Carolina?
Expedia makes it a cinch to locate cheap lake hotels in South Carolina. Simply use our convenient filter tool to select your budget and preferred hotel star rating. You can also search for your dream lakeside stay based on neighborhoods and popular locations.
What is there to do in South Carolina near my lakeside hotel?
Whether you're passionate about food, shopping, history or sightseeing, South Carolina is one place you'll never get bored! The fabulous city of Charleston has tons of things to do, including South Carolina Aquarium, Charleston Museum and Dock Street Theater. If you're taking off to Myrtle Beach, Broadway at the Beach, SkyWheel Myrtle Beach and Ripley's Aquarium have to be on your itinerary.