Lakefront Hotels & Resorts in South Carolina

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Top Cities in South Carolina

HotelsHotels

Charleston

Charleston

Check availability on South Carolina Lake Hotels

Our top choices for South Carolina hotels on the lake

Exterior

Relax on the shore of Lake Hartwell in our Fair Play retreat

Relax on the shore of Lake Hartwell in our Fair Play retreat
Fair Play
9.8 out of 10, Exceptional, (236 reviews)
"The property was lovely and accurate to what the hosts described. We would definitely stay here again!"
United States
Lawren C.
Relax on the shore of Lake Hartwell in our Fair Play retreat
Smart TV, fireplace, DVD player, toys

😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks

😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks
Seneca
10.0 out of 10, Exceptional, (236 reviews)
"Amazing home.....generous host "
United States
Johnny C.
😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks
Golf

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.6 out of 10, Exceptional, (968 reviews)
"Everything was very nice "
United States
Paige
The price is CA $202
CA $224 total
includes taxes & fees
Feb 15 - Feb 16
Clemson University's James F. Martin Inn
Terrace/patio

Hampton Inn Columbia I-26/Harbison Blvd.

Hampton Inn Columbia I-26/Harbison Blvd.
2.5 star property
St. Andrews
9.0 out of 10, Wonderful, (1,003 reviews)
"The room was very clean, the continental breakfast was great. We only stayed one night but the staff was very nice and welcoming. "
United States
Yolanda
The price is CA $132
CA $148 total
includes taxes & fees
Feb 22 - Feb 23
Hampton Inn Columbia I-26/Harbison Blvd.
Rooftop terrace

Charleston Kiawah Island/Andell Inn

Charleston Kiawah Island/Andell Inn
3.5 star property
Kiawah Island
9.6 out of 10, Exceptional, (525 reviews)
"Great hotel and close to everything"
United States
Debra
The price is CA $473
CA $558 total
includes taxes & fees
Feb 22 - Feb 23
Charleston Kiawah Island/Andell Inn
Property grounds

Scenic Carolina Waterfront Rentals - Arco

Scenic Carolina Waterfront Rentals - Arco
Charleston
9.4 out of 10, Exceptional, (84 reviews)
"We really enjoyed the house. We will be back. "
United States
mauricio o.
Scenic Carolina Waterfront Rentals - Arco
Lobby

Days Inn by Wyndham Columbia

Days Inn by Wyndham Columbia
2.0 star property
St. Andrews
4.2 out of 10, (1,002 reviews)
"The sink clogged during the second day."
United States
Shawn
The price is CA $65
CA $73 total
includes taxes & fees
Mar 1 - Mar 2
Days Inn by Wyndham Columbia
Smart TV, DVD player, books, music library

EXCEPTIONAL Large and Private Villa in Palmetto Dunes Resort!! 5-Star Reviews!!!

EXCEPTIONAL Large and Private Villa in Palmetto Dunes Resort!! 5-Star Reviews!!!
Mid Island
10.0 out of 10, Exceptional, (273 reviews)
"Good experience - great communication from owner"
United States
Jacob V.
EXCEPTIONAL Large and Private Villa in Palmetto Dunes Resort!! 5-Star Reviews!!!
Fridge, microwave, oven, stovetop

Lakefront 3 Bedroom, 2 Bath and Pet Friendly Near Chattooga River and Belle Farm

Lakefront 3 Bedroom, 2 Bath and Pet Friendly Near Chattooga River and Belle Farm
Long Creek
9.8 out of 10, Exceptional, (49 reviews)
"This was an amazing property and close to all of our weekend activities. Absolutely felt like home. "
United States
Ashley M.
Lakefront 3 Bedroom, 2 Bath and Pet Friendly Near Chattooga River and Belle Farm
Exterior

Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (643 reviews)
"A good option if traveling with pets. The hotel is clean and well maintained but dated. "
United States
Karen
The price is CA $88
CA $97 total
includes taxes & fees
Feb 17 - Feb 18
Red Roof Inn Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Book now
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top South Carolina Hotel Reviews

The Francis Marion Hotel

The Francis Marion Hotel

10/10 Excellent
"Such a beautiful historic property. Excellent experience! "
Ellisia 1-night trip
Posted 2 days ago
The Francis Marion Hotel

Explore a world of travel with Expedia

Frequently asked questions

How much do lakeside hotels in South Carolina cost?
Lakeside hotels in South Carolina range between CA $73 and CA $558 per night. This means you can look forward to a getaway close to the water at a price that won't break the bank. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best lakeside hotels in South Carolina?
South Carolina offers multiple lakeside hotels with a total average guest review rating of 8.8. Planning a getaway to Myrtle Beach? Stay at Hampton Inn & Suites Myrtle Beach/Oceanfront, a popular 3-star option with a terrace and hypo-allergenic bedding. Another recommended lake hotel is Hampton Inn Myrtle Beach Broadway at the Beach. It has a 2.5-star rating and amenities including complimentary use of a nearby fitness centre and a swimming pool.
How many lakeside hotels are there in South Carolina?
Explore our 147 hotels near lakes in South Carolina and then book your favorite. Whether you're embarking on a family escape or jet-setting with friends, your perfect lakeside stay is just a keystroke away with Expedia.
Are there any family-friendly lakeside hotels in South Carolina?
You'll discover some wonderful family-friendly hotels near a lake in South Carolina. If you're vacationing in Myrtle Beach, take a look at Hampton Inn & Suites Myrtle Beach/Oceanfront. With amenities such as a children's pool and a playground, your entire crew will enjoy chilling out at this 3-star property. Kingston Plantation Condos is another top pick for families seeking a lakeside retreat in Myrtle Beach. This 3.5-star option offers a waterslide, a playground and more. You'll discover lots of fabulous things to do with your team in Myrtle Beach. Myrtle Beach Boardwalk and Broadway at the Beach offer a fantastic day out.
Why book your lakeside hotel in South Carolina with Expedia?
Expedia has the best deals on lakeside hotels in South Carolina. But our fabulous prices are just the start. You'll discover plenty of hotels to pick from and clever search filters that make it a breeze to find your ideal getaway.
How can I find cheap lakeside hotels in South Carolina?
Expedia makes it a cinch to locate cheap lake hotels in South Carolina. Simply use our convenient filter tool to select your budget and preferred hotel star rating. You can also search for your dream lakeside stay based on neighborhoods and popular locations.
What is there to do in South Carolina near my lakeside hotel?
Whether you're passionate about food, shopping, history or sightseeing, South Carolina is one place you'll never get bored! The fabulous city of Charleston has tons of things to do, including South Carolina Aquarium, Charleston Museum and Dock Street Theater. If you're taking off to Myrtle Beach, Broadway at the Beach, SkyWheel Myrtle Beach and Ripley's Aquarium have to be on your itinerary.