Name: Comfort Inn & Suites Florence Center Area
Price range: CA $161
Rating: 9

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Your Florence Vacation

With a Florence vacation package, say goodbye to travel planning and hello to an effortless adventure. Every detail of your escape has been taken care of before you go, so you can get on with experiencing this awesome city. If your trip to Florence includes some sightseeing, hit up well-known attractions like Florence Civic Center, Magnolia Mall and Florence National Cemetery. Check out Expedia's wide range of travel options and start organizing your perfect vacation to Florence today.

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Florence Hotel Deals

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC

Fully refundable

CA $133

CA $149 total

Jul 5 - Jul 6

includes taxes & fees

9/10 Wonderful! (2,319 reviews)

"Very comfortable. Very clean."

Reviewed on Jun 22, 2026

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC

Fully refundableReserve now, pay when you stay

CA $96

CA $107 total

Jun 24 - Jun 25

includes taxes & fees

8.6/10 Excellent! (2,686 reviews)

"Nice management and staff."

Reviewed on Jun 22, 2026

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC

Fully refundable

CA $161

CA $180 total

Jul 6 - Jul 7

includes taxes & fees

9/10 Wonderful! (1,304 reviews)

"Staff was great and bed very comfortable"

Reviewed on Jun 23, 2026

See all 403 properties in Florence

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.