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La Mesa Vacation Rentals

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Vacation Rentals in La Mesa

Little Italy Inn - Limited Service Apart Hotel

2.5 star property
8.0 out of 10, Very good, (15)
"Hotel was clean and well located and very reasonably priced for the room. Parking was a little expensive but overall very happy with our stay at this hotel considering most other hotels in downtown San Diego are significantly more expensive. We would stay here again. "
The price is CA $147
CA $167 total
includes taxes & fees
Aug 12 - Aug 13
Little Italy Inn - Limited Service Apart Hotel

Kasa Little Italy San Diego

4.5 star property
9.6 out of 10, Exceptional, (238)
"Wonderful stay, had everything we needed"
The price is CA $240
CA $394 total
includes taxes & fees
Jul 21 - Jul 22
Kasa Little Italy San Diego

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

2.5 star property
8.2 out of 10, Very good, (195)
"Nice little rooms, really comfortable bed"
The price is CA $149
CA $168 total
includes taxes & fees
Aug 5 - Aug 6
Uptown Inn by Vantaggio - Limited Service Apart-Hotel

City24 Hotel Little Italy Mission Hill

4.5 star property
9.6 out of 10, Exceptional, (77)
"Great place for a reasonable price and in excellent condition. The only downside was its proximity to the airport and the noise early in the morning but that was to be expected. I would definitely stay there again. "
The price is CA $196
CA $261 total
includes taxes & fees
Jul 29 - Jul 30
City24 Hotel Little Italy Mission Hill

Kasa Gaslamp Quarter San Diego

3.5 star property
8.0 out of 10, Very good, (118)
"Nice and close to restaurants and bars , and really close to the convention center. Also super easy check in / check out experience"
The price is CA $171
CA $195 total
includes taxes & fees
Jul 28 - Jul 29
Kasa Gaslamp Quarter San Diego

Coronado Beach Resort

3.0 star property
9.0 out of 10, Wonderful, (708)
"Great hotel, location walkable to beach"
The price is CA $323
CA $355 total
includes taxes & fees
Jul 23 - Jul 24
Coronado Beach Resort

Inn at the Park by WorldMark

2.0 star property
Inn at the Park by WorldMark

Charming Smart 2-bedroom house with Hottub, WiFi & EV Charger in sunny San Diego

8.6 out of 10, Excellent, (10)
"This home was definitely as described in the listing. Great place, smooth check in process, clean, etc."
Charming Smart 2-bedroom house with Hottub, WiFi & EV Charger in sunny San Diego

OCEAN VIEWS! New Modern Style House-Great for Groups and Families

9.6 out of 10, Exceptional, (97)
"We had a great time. Great property."
OCEAN VIEWS! New Modern Style House-Great for Groups and Families

Sunset Cliffs Oceanfront Oasis, San Diego - Stunning Views & Ocean Sounds.

9.6 out of 10, Exceptional, (118)
"Our stay at this property was absolutely excellent! The balcony was a standout feature— serene, and offering spectacular views of the ocean. We spent time relaxing and watching the surfers right from the balcony—it felt like our own private front-row seat to the waves. The home was spotless, cozy, and had everything we needed for a comfortable stay. The host’s instructions were clear and easy to follow, which made the entire experience seamless from check-in to check-out. The pantry in kitchen...
Sunset Cliffs Oceanfront Oasis, San Diego - Stunning Views & Ocean Sounds.

Ocean Beach #2 ‘Garden’ Cozy Cottage - Walk to the beach!

9.4 out of 10, Exceptional, (155)
"We had the best weekend trip. Easy access to the beach, restaurants, and shopping. Excellent communication with owner. We will definitely stay here again. "
Ocean Beach #2 ‘Garden’ Cozy Cottage - Walk to the beach!

Boutique Luxury in Upscale Area with Private Entry & Bath, Villa A

9.8 out of 10, Exceptional, (79)
"Great place to stay in a quiet neighborhood."
Boutique Luxury in Upscale Area with Private Entry & Bath, Villa A

3 min walk 2 beach!13+guests for 4 bedrooms!guest house included with 13+guests!

9.2 out of 10, Wonderful, (52)
"Stayed here for my bachelor party and had an absolute blast! Awesome place, great location and the host was incredible and super accommodating! Would 10/10 recommend and would definitely stay here again!"
3 min walk 2 beach!13+guests for 4 bedrooms!guest house included with 13+guests!

San Diego Beachfront/Oceanfront: 180 degree oceanfront view!

9.6 out of 10, Exceptional, (317)
"This place has it all. Highly recommend."
San Diego Beachfront/Oceanfront: 180 degree oceanfront view!

Chic & Spacious Studio by the Beach Prime La Jolla Spot Sleeps 4!

10.0 out of 10, Exceptional, (2)
"Very good area, near everything "
The price is CA $204
CA $509 total
includes taxes & fees
Aug 5 - Aug 6
Chic & Spacious Studio by the Beach Prime La Jolla Spot Sleeps 4!

Stunning 7BR Estate-Guest House, Pool, Spa, Views!

9.2 out of 10, Wonderful, (9)
"Highly recommend this property for a large group. We stayed here for a bachelorette weekend. The pool/ jacuzzi, ping pong table and games kept everyone entertained. We had a comfortable stay. "
Stunning 7BR Estate-Guest House, Pool, Spa, Views!

Heated pool, hot tub & waterslides near the beach!

9.8 out of 10, Exceptional, (195)
"This was an awesome house! We all had a great time. The pool was fantastic. The location was absolutely great. "
Heated pool, hot tub & waterslides near the beach!

Oceanfront bungalow with spectacular views & W/D - near Mission/Pacific Beach

8.8 out of 10, Excellent, (94)
"This property is such a hidden gem! We enjoyed every moment of our stay here. "
Oceanfront bungalow with spectacular views & W/D - near Mission/Pacific Beach

WaterFront * Exclusive View Patio * Top Level * A/C

9.8 out of 10, Exceptional, (102)
"Perfect location! Cute and the bed was super comfortable!"
WaterFront * Exclusive View Patio * Top Level * A/C

Roam and Board

2.0 star property
Roam and Board
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are there vacation rentals in La Mesa?

Yes, you can find vacation rentals in La Mesa near Computer Museum of America, or you can choose a secluded option if you'd like a relaxing place to stay. Visitors like the top-notch restaurants and shops in La Mesa. Leave some time to check out the zoo and entertainment venues during your trip.

What are some of the best vacation rentals that La Mesa has to offer?

OCEAN VIEWS! New Modern Style House-Great for Groups and Families: Visitors like this La Mesa vacation home rental. It is located near the beach and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

How many vacation rentals are there in La Mesa?

With 108 Expedia vacation rentals, you're sure to find just the right place for your La Mesa stay.

What can I see and do in La Mesa?

Explore the area and cultural attractions such as Computer Museum of America, or visit a family-friendly sight such as San Diego Zoo. While in the area, you can also visit popular places like Mission Bay and San Ysidro Border Crossing.

What are vacation rentals like in La Mesa?

Vacation rentals are privately owned properties you can book for several days or more in La Mesa. Vacation rentals feature amenities such as WiFi and washers and dryers so you'll have everything you need. If you're concerned about a clean environment, vacation rentals can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a great choice for families.