Upstate South Carolina Vacation Packages

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Your Upstate South Carolina Vacation

With a Upstate South Carolina vacation package, you can forget about the stress of planning and simply focus on experiencing what this thrilling destination has on offer. With so much to do and see on a trip to Upstate South Carolina, it can be hard to know where to begin. Kick off your travels in Greenville at Falls Park on the Reedy and Bon Secours Wellness Arena — two popular attractions here. Another top city worthy of a spot on your itinerary is Spartanburg. Don't miss WestGate Mall and Tyger River Park. Expedia is your one-stop shop for planning your Upstate South Carolina vacation. From hotels and flights, to car rentals and more, we're here to help you create a travel experience like no other.

Top Upstate South Carolina Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Hampton Inn Charlotte-Uptown

Hampton Inn Charlotte-Uptown

2.5 out of 5
Uptown Charlotte
per person
Sep 25 - Sep 29
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to Charlotte (CLT)
8.6/10 Excellent! (1,413 reviews)
The front desk staff was super nice and helpful! Esp the new manager!

Reviewed on Aug. 12, 2025

The Westin Charlotte

The Westin Charlotte

4 out of 5
Uptown Charlotte
per person
Oct 6 - Oct 9
found 7 hours ago
Roundtrip non-stop flight included
Montreal (YUL) to Charlotte (CLT)
9/10 Wonderful! (1,001 reviews)
The hotel was clean staff was friendly nice restaurant also plenty of close by places that you could walk to to eat it's also right beside the convention center and there's a Whole Foods Market next door that has a nice salad bar with hot and cold food and little snacks that you can get if you don't want to buy anything in the restaurants in the hotel

Reviewed on Aug. 15, 2025

Lake Days by Avantstay Hot Tub + Firepit + Game Room & Private Dock Access

Lake Days by Avantstay Hot Tub + Firepit + Game Room & Private Dock Access

3 out of 5
per person
Sep 25 - Sep 29
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to Charlotte (CLT)
No reviews
Charlotte Marriott City Center

Charlotte Marriott City Center

4 out of 5
Uptown Charlotte
per person
Oct 17 - Oct 21
found 1 day ago
Roundtrip non-stop flight included
Ottawa (YOW) to Charlotte (CLT)
8.8/10 Excellent! (1,002 reviews)
Nice place to stay, close to stadium

Reviewed on Aug. 12, 2025

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
per person
Oct 27 - Nov 3
found 12 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Greenville (GSP)
8.6/10 Excellent! (1,009 reviews)
Great hotel , would stay again .

Reviewed on Aug. 16, 2025

Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville which includes autumn leaves, a garden and a bridge

Greenville Downtown

3 out of top 10 points of interest in this area
5/5(3 area reviews)

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Find hotels in Greenville Downtown

Ready to book your vacation to Upstate South Carolina?

 

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Upstate South Carolina Hotel Deals

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd, Greenville, SC
Fully refundable
The price is CA $131 per night from Aug 22 to Aug 23
CA $131
CA $144 total
Aug 22 - Aug 23
includes taxes & fees
8.4/10 Very Good! (1,000 reviews)
"Staff was great hotel was clean"

Reviewed on Aug. 8, 2025

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is CA $187 per night from Aug 24 to Aug 25
CA $187
CA $211 total
Aug 24 - Aug 25
includes taxes & fees
8.6/10 Excellent! (1,003 reviews)
"The restaurant was under construction and had limited menu and no food service at bar The food I had was very tasty"

Reviewed on Aug. 11, 2025

Hyatt Regency Greenville
Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is CA $113 per night from Aug 21 to Aug 22
CA $113
CA $128 total
Aug 21 - Aug 22
includes taxes & fees
8/10 Very Good! (1,003 reviews)
"Everything was excellent."

Reviewed on Aug. 15, 2025

Hilton Greenville
See all 2,826 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Discover the most popular places to visit in Upstate South Carolina

Fred W. Symmes Chapel

Fred W. Symmes Chapel

You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.

Fred W. Symmes Chapel

Greenville Convention Center

Learn about the events happening at Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

Greenville Convention Center

Wofford College

Take a campus tour or just explore the area of Wofford College, during your trip to Spartanburg. Experience the area's theater scene or attend a sporting event.

Wofford College

What to do in Upstate South Carolina

Just Desserts Tour In Greenville

Just Desserts Tour In Greenville

CA $116
per adult
Just Desserts Tour In Greenville
Paranormal Walking Tour by Greenville Ghost Tours

Paranormal Walking Tour by Greenville Ghost Tours

CA $48
per adult
Paranormal Walking Tour by Greenville Ghost Tours
Delicious breakfast on a sunny Saturday morning on the terrace

Small-Group Walking Tour in Greenville with Breakfast

CA $110
per adult
100% of travellers recommend
Small-Group Walking Tour in Greenville with Breakfast
See all activities in Upstate South Carolina

Frequently asked questions

How much does a Upstate South Carolina vacation package cost?
Our Upstate South Carolina vacation packages, which begin from just CA $946, are an awesome way to save loads of cash. Choose your preferred flights, hotels and rental cars to create your dream getaway.
How do I get a cheap travel package to Upstate South Carolina?
You'll save piles of cash if you bundle your hotels, flights and car rentals into a Upstate South Carolina vacation package. Sometimes cheap packages mean fewer options. But that's not the case with Expedia. We offer more than 550 partner airlines and 1,000,000 hotels across the world, so you'll always have plenty of options to choose from. Eager to save even more? Add some fun activities to your package deal to unlock even bigger bargains! After all, travel is about more than simply getting to your destination.
Where should I stay in Upstate South Carolina?
Falls Park on the Reedy is one of the main things that attracts visitors to Upstate South Carolina, so it makes perfect sense that many choose to book their hotel in Greenville.
What are the top hotels in Upstate South Carolina?
Best Western Plus Greenville I-385 Inn & Suites and Comfort Inn Greenville - Haywood Mall know how to make their guests feel at home in Greenville. If you also plan to explore Seneca, take a look at Quality Inn Seneca US-123 and Tru by Hilton Seneca Clemson. Both are very popular with travelers.
How far in advance should I book my Upstate South Carolina vacation?
It can be hard to know exactly when the best time is to book your Upstate South Carolina vacation. But typically the earlier you book, the more affordable the prices. Sometimes, you can lock in your flights and hotels up to 12 months prior to departure. If you're considering a last-minute getaway, no need to fret! There are plenty of fantastic bargains announced on Expedia every single day.
What does an Expedia Upstate South Carolina travel package include?
That depends on what sort of trip you have in mind. Upstate South Carolina vacation deals can include car rentals, flights and hotels. You can mix and match to find the travel package that suits your budget and style. You can also add on activities and experiences after you've booked to score even bigger discounts.
What should I know before booking a Upstate South Carolina travel package?
An Expedia travel package can be customized for your budget and is a fantastic way to make your budget go further. What you include is totally up to you. Rental cars, hotels and flights — decide on a combination that suits your style.
Can I choose my airline with a Upstate South Carolina Expedia vacation package?
Yes, of course. Expedia has access to more than 550 airline partners globally, so go with the carrier that best fits your budget and travel needs.
If I'm not able to travel, can I cancel my Upstate South Carolina vacation package?
If your travel plans in Upstate South Carolina have been upended, it's comforting to know that you can cancel your booking. If you made your booking in the last 24 hours, you may be eligible for a refund. If your booking was made more than 24 hours ago, your airline, hotel or car rental company may impose fees. To learn more, check our Customer Service Portal.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.