Title: Book The Best Hotels in Cairo, IL for 2025 from CA $72 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Cairo](https://expedia.ca/Cairo-Vacation-Rentals.d6626.Travel-Guide-VacationRentals)[Flights to Cairo](https://expedia.ca/Cheap-Flights-To-Cairo.d6626.Travel-Guide-Flights)[Cairo Car Rentals](https://expedia.ca/Car-Rentals-In-Cairo.d6626.Car-Rental-Guide)[Cairo Vacation Packages](https://expedia.ca/Cairo.d6626.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Cairo, IL from CA $72 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Cairo Cabin [](https://www.expedia.ca/Hotel-Search?destination=Cairo%2C+Illinois%2C+United+States+of+America®ionId=6626&latLong=37.005329%2C-89.176461&adults=2&startDate=2025-10-01&d1=2025-10-01&endDate=2025-10-03&d2=2025-10-03&lodging=CABIN) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Cairo%2C+Illinois%2C+United+States+of+America®ionId=6626&latLong=37.005329%2C-89.176461&adults=2&startDate=2025-10-01&d1=2025-10-01&endDate=2025-10-03&d2=2025-10-03&amenities=PETS) ## Check prices for these dates Tonight [Sep 17 - Sep 18](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2025-09-17&endDate=2025-09-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 18 - Sep 19](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2025-09-18&endDate=2025-09-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 19 - Sep 21](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2025-09-19&endDate=2025-09-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 27 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ## Our top choices for Cairo hotels ![Basic Double Room](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/6218157c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Double Room | Living area](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/dc7ca140.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/520db902.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/bbe54b21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Center Motel La Center 8.0/10 Very good (15) "The place was very clean" CA $72 CA $85 total includes taxes & fees Sep 19 - Sep 20 [](https://www.expedia.ca/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/f1c41457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/c71a6d1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/0feda7c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cairo I-57 Cairo 6.6/10 (268) "The room smelled like pee and the carpets, hallway and room were filthy. The shower was filthy with paint peeling and mold on the ceiling " CA $92 CA $102 total includes taxes & fees Sep 27 - Sep 28 [](https://www.expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/a5038447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/bbf96e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Charleston/Sikeston East MO Charleston 6.6/10 (591) "Rooms was clean " CA $80 CA $88 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/d2862bfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/074a1dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/fa992d12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/94d9e92f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Charleston - Sikeston Charleston 6.8/10 (400) "I consistently choose to stay there due to positive past encounters." CA $90 CA $100 total includes taxes & fees Sep 24 - Sep 25 [](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn-Charleston-I-57.h20594.Hotel-Information) ![Desk, iron/ironing board, free WiFi, alarm clocks](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/228b486a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/ec6ce079.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/2b61a8ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/e769dedb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eagle Inn Charleston Charleston 6.8/10 (101) "Comfortable bed, easy access to room" CA $88 CA $97 total includes taxes & fees Sep 21 - Sep 22 [](https://www.expedia.ca/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-02&endDate=2025-10-03®ionId=6626&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCairo-Hotels.d6626.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCairo-Hotels.d6626.Travel-Guide-Hotels) ### Stay near popular Cairo attractions [](https://expedia.ca/Fort-Defiance-State-Park-Hotels.0-l6091411-0.Travel-Guide-Filter-Hotels) #### Fort Defiance State Park You can take time to visit Fort Defiance State Park during your travels to Cairo. Stroll along the riverfront or visit the churches while you're in the area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6091411) ## More cheap stays in Cairo ![Super 8 by Wyndham Charleston/Sikeston East MO](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Charleston/Sikeston East MO 310 S Story St, Charleston, MO CA $80 CA $88 total Oct 14 - Oct 15 includes taxes & fees 6.6/10 (590 reviews) [](https://expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Quality Inn Charleston - Sikeston](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/d2862bfb_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Charleston - Sikeston 102 Drake St, I-57 Exit 10, Charleston, MO CA $90 CA $100 total Sep 24 - Sep 25 includes taxes & fees 6.8/10 (400 reviews) [](https://expedia.ca/Sikeston-Hotels-Quality-Inn-Charleston-I-57.h20594.Hotel-Information) ![Quality Inn Cairo I-57](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Cairo I-57 13201 Kessler Road, Cairo, IL CA $92 CA $102 total Sep 27 - Sep 28 includes taxes & fees 6.4/10 (268 reviews) [](https://expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) ![La Center Motel](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/6218157c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### La Center Motel 474 W Kentucky Dr, La Center, KY CA $72 CA $85 total Sep 19 - Sep 20 includes taxes & fees 7.8/10 Good! (15 reviews) [](https://expedia.ca/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information) ![Eagle Inn Charleston](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/228b486a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Eagle Inn Charleston 2811 East Marshall Street, Charleston, MO CA $88 CA $97 total Sep 21 - Sep 22 includes taxes & fees 6.6/10 (101 reviews) [](https://expedia.ca/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) ![Welcome campers, hikers, fishermen, girls' weekend wine getaways!!](https://images.trvl-media.com/lodging/110000000/109110000/109109100/109109006/bd476bf3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Welcome campers, hikers, fishermen, girls' weekend wine getaways!! Tamms [Get rates](https://expedia.ca/Hotel-Search?startDate=02%2F10%2F2025&endDate=03%2F10%2F2025&selected=109109006&PinnedHotelID=109109006&HadPinnedHotel=true®ionId=6626) 9.8/10 Exceptional! (18 reviews) [](https://expedia.ca/Tamms-Hotels-Attention-Hunters-Deer-Camp.h109109006.Hotel-Information) ## Hotels in Cairo with star-rating ![3 Star Hotels](https://images.trvl-media.com/lodging/94000000/93570000/93561400/93561320/f8346cc4_w.jpg) 3 Star Hotels 1 properties [](https://expedia.ca/3Star-Cairo-Hotels.s30-0-d6626.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39_z.jpg) 2 Star Hotels 6 properties [](https://expedia.ca/2Star-Cairo-Hotels.s20-0-d6626.Travel-Guide-Filter-Hotels) ## Recent reviews of Cairo hotels ![La Center Motel](//images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/6218157c_y.jpg) ### La Center Motel 5/5 Excellent "The place was very clean" A verified traveller stayed at La Center Motel Posted 7 days ago [](https://expedia.ca/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information) ![Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286](//images.trvl-media.com/lodging/54000000/53860000/53856300/53856204/f8ac9a8a_y.jpg) ### Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286 5/5 Excellent "Very clean and comfortable stay in the country" A verified traveller stayed at Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286 Posted 10 days ago [](https://expedia.ca/Quiet-Home-On-Horse-Farm.h53856204.Hotel-Information) ![Beautiful newly renovated farm house overlooking 5 acre lake. ****New Rates ***](//images.trvl-media.com/lodging/69000000/68040000/68038600/68038535/956cd1de_y.jpg) ### Beautiful newly renovated farm house overlooking 5 acre lake. \*\*\*\*New Rates \*\*\* 5/5 Excellent "This place was absolutely beautiful! The home is wonderfully restored and shows the history of the property. The lake was excellent for kayaking and fishing. We saw deer near the lake in the evenings. The home is also well stocked with everything you will need for your stay." A verified traveller stayed at Beautiful newly renovated farm house overlooking 5 acre lake. \*\*\*\*New Rates \*\*\* Posted 2 weeks ago [](https://expedia.ca/Dongola-Hotels-Beautiful-Newly-Renovated-Farm-House-Overlooking-5-Acre-Lake-New-Rates.h68038535.Hotel-Information) ![Charming cottage overlooking Lake Acre](//images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/7bfe8087_y.jpg) ### Charming cottage overlooking Lake Acre 5/5 Excellent "Location was great, everything was great for what we were there for. Already booked again for November. " A verified traveller stayed at Charming cottage overlooking Lake Acre Posted 2 weeks ago [](https://expedia.ca/Charming-Cabin-Overlooking-5-Acre-Lake.h39671140.Hotel-Information) ![Peaceful secluded cabin located near Horseshoe Lake ](//images.trvl-media.com/lodging/110000000/109740000/109730100/109730068/b6736ddb_y.jpg) ### Peaceful secluded cabin located near Horseshoe Lake 5/5 Excellent "cute A frame in a secluded spot. Couldn’t ask for a more relaxing situation. " A verified traveller stayed at Peaceful secluded cabin located near Horseshoe Lake Posted 2 weeks ago [](https://expedia.ca/Peaceful-Secluded-Cabin-Located-Near-Horseshoe-Lake.h109730068.Hotel-Information) ![The Rested Duck Mallard Room](//images.trvl-media.com/lodging/91000000/90340000/90331100/90331048/29d5afe7_y.jpg) ### The Rested Duck Mallard Room 5/5 Excellent "This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure" A verified traveller stayed at The Rested Duck Mallard Room Posted 3 weeks ago [](https://expedia.ca/The-Rested-Duck-Mallard-Room.h90331048.Hotel-Information) ![Super 8 by Wyndham Charleston/Sikeston East MO](//images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39_y.jpg) ### Super 8 by Wyndham Charleston/Sikeston East MO 5/5 Excellent Big rooms "We stay here a lot. It is conveniently located. We like the nice big rooms. " A verified traveller stayed at Super 8 by Wyndham Charleston/Sikeston East MO Posted 1 month ago [](https://expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Quality Inn Charleston - Sikeston](//images.trvl-media.com/lodging/1000000/30000/20600/20594/d2862bfb_y.jpg) ### Quality Inn Charleston - Sikeston 5/5 Excellent "The staff was very friendly and accommodating " A verified traveller stayed at Quality Inn Charleston - Sikeston Posted 1 month ago [](https://expedia.ca/Sikeston-Hotels-Quality-Inn-Charleston-I-57.h20594.Hotel-Information) ![Cozy cabins on beautiful Horseshoe Lake](//images.trvl-media.com/lodging/91000000/90340000/90331200/90331191/53db6388_y.jpg) ### Cozy cabins on beautiful Horseshoe Lake 5/5 Excellent "Beautiful place, host was kind and and quick to respond to messages " A verified traveller stayed at Cozy cabins on beautiful Horseshoe Lake Posted 2 months ago [](https://expedia.ca/Cozy-Cabins-On-Beautiful-Horseshoe-Lake.h90331191.Hotel-Information) ## Frequently asked questions ### What are the best budget hotels in Cairo? > [Quality Inn Cairo I-57](https://www.expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) stands out as a fantastic budget-friendly option for travellers seeking comfort and convenience without breaking the bank. This hotel offers a range of amenities designed to make your stay enjoyable and stress-free, including complimentary full breakfast and free WiFi, ensuring you stay connected and well-fed during your adventures. View all [budget hotels in Cairo](https://www.expedia.ca/cairo-hotels-cheap-hotels.0-0-d6626-tcheaphotels.travel-guide-filter-hotels). ### When is the best time to go to Cairo? > The most popular time to visit Cairo is March. During this month, the city experiences pleasant temperatures ranging from 18 to 25 Celsius, making it an ideal time for outdoor exploration and cultural immersion. This comfortable climate allows you to wander through the vibrant streets, visit breathtaking historical sites, and enjoy leisurely strolls along the Nile. > > > > As you venture into the peak season from March to May, you'll find an increase in tourist activity, with visitors flocking to iconic landmarks such as the Pyramids of Giza and the Egyptian Museum. The warm weather and clear skies provide an excellent backdrop for sightseeing, ensuring that you can fully appreciate the rich history and stunning architecture that Cairo has to offer. > > > > For those who appreciate a more tranquil atmosphere while still enjoying the city's attractions, consider planning your visit in November. During this time, you may find fewer crowds, allowing for a more intimate experience as you explore Cairo's treasures at a leisurely pace. ### Can I cancel my hotel reservation on Expedia? > You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Cairo. ### How can I save on a Cairo hotel booking with Expedia? > With Expedia, you'll unlock our lowest prices by becoming a member. It's free and easy to join, and you can even access member perks too. Just remember to sign in to get our best prices on Cairo hotels. Another way to save is by booking your hotel and flights together on Expedia, where bundling can lead to significant savings. ### How much is the nightly rate at a Cairo hotel? > Prices for hotels in Cairo often vary, but you can find a great deal from CA $72 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. 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