Title: Book The Best Hotels in Cairo, IL for 2026 from CA $91 - Fully Refundable Options - Expedia.ca

[Vacation Rentals in Cairo](https://expedia.ca/Cairo-Vacation-Rentals.d6626.Travel-Guide-VacationRentals)[Flights to Cairo](https://expedia.ca/Cheap-Flights-To-Cairo.d6626.Travel-Guide-Flights)[Cairo Car Rentals](https://expedia.ca/Car-Rentals-In-Cairo.d6626.Car-Rental-Guide)[Cairo Vacation Packages](https://expedia.ca/Cairo.d6626.Destination-Travel-Guides)

![Cairo Ohio River Bridge traversing over the Ohio River at sunset](https://images.trvl-media.com/place/6626/5a2a2e7f-cbef-414c-a9c1-20af7a0fca3a.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6626/5a2a2e7f-cbef-414c-a9c1-20af7a0fca3a.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Go beyond your typical stay in Cairo

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Cairo%2C+Illinois%2C+United+States+of+America&regionId=6626&latLong=37.005329%2C-89.176461&adults=2&startDate=2026-02-11&d1=2026-02-11&endDate=2026-02-13&d2=2026-02-13&amenities=PETS)

Cabin

[](https://www.expedia.ca/Hotel-Search?destination=Cairo%2C+Illinois%2C+United+States+of+America&regionId=6626&latLong=37.005329%2C-89.176461&adults=2&startDate=2026-02-11&d1=2026-02-11&endDate=2026-02-13&d2=2026-02-13&lodging=CABIN)

## Check prices for these dates

Tonight

[Jan 28 - Jan 29](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2026-01-28&endDate=2026-01-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Jan 29 - Jan 30](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2026-01-29&endDate=2026-01-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Cairo hotels

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/f1c41457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/e2b2c624.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/74187a0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Cairo I-57

[](https://www.expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information)

Cairo

6.6/10

(276 reviews)

"The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6\. I was not satisfied at all."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

ReShena

CA $107

CA $119 total

includes taxes & fees

Jan 30 - Jan 31

[](https://www.expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information)

![Basic Double Room | Living area](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/e95f9062.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/f3adf3f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/bbe54b21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Double Room](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/1016c5b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Center Motel

[](https://www.expedia.ca/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information)

La Center

7.8/10

Good

(17 reviews)

"Quiet and convenient."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alma

[](https://www.expedia.ca/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information)

![Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/1ca277a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/bbf96e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Charleston/Sikeston East MO

[](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information)

Charleston

6.8/10

(622 reviews)

"Affordable for a quick one night stay. Restaurant and gas station next to hotel."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Annette

CA $84

CA $94 total

includes taxes & fees

Jan 29 - Jan 30

[](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information)

![Room, 1 King Bed, Non Smoking | View from room](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/183a17d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/352edf3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, alarm clocks](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/228b486a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Coffee service](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/8720ff7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Eagle Inn Charleston

[](https://www.expedia.ca/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information)

Charleston

6.6/10

(105 reviews)

"Middle of nowhere hotel was ok"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

CA $82

CA $91 total

includes taxes & fees

Jan 29 - Jan 30

[](https://www.expedia.ca/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/9b8cfc2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/a51b6a8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/2ea775b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/fe5a3b48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quiet Country Stay: Modern Home Near Paducah

[](https://www.expedia.ca/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122892138.Hotel-Information)

Cunningham

CA $164

CA $394 total

includes taxes & fees

Jan 29 - Jan 30

[](https://www.expedia.ca/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122892138.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-11&endDate=2026-02-12&regionId=6626&adults=2&sort=RECOMMENDED&openPlayBack=true)

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## Learn more about Cairo

At the confluence of the Mississippi and Ohio rivers, explore Cairo's historic Fort Defiance Park with its sweeping water views. History buffs shouldn't miss the Custom House Museum, where you can discover artifacts from this once-thriving river port town.

[See all hotels in Cairo](https://www.expedia.ca/Hotel-Search?startDate=2026-02-11&endDate=2026-02-12&adults=2&regionId=6626)

![Cairo Ohio River Bridge traversing over the Ohio River at sunset](https://images.trvl-media.com/place/6626/5a2a2e7f-cbef-414c-a9c1-20af7a0fca3a.jpg?impolicy=fcrop&w=899&h=599&p=1&q=high)

### Stay near popular Cairo attractions

[](https://expedia.ca/Fort-Defiance-State-Park-Hotels.0-l6091411-0.Travel-Guide-Filter-Hotels)

#### Fort Defiance State Park

You can take time to visit Fort Defiance State Park during your travels to Cairo. Stroll along the riverfront or visit the churches while you're in the area. 

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6091411)

## More cheap stays in Cairo

![Eagle Inn Charleston](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/228b486a_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Eagle Inn Charleston

2811 East Marshall Street Charleston MO

CA $82

CA $91 total

Jan 29 - Jan 30

includes taxes & fees

6.6/10 (105 reviews)

[](https://expedia.ca/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information)

![Super 8 by Wyndham Charleston/Sikeston East MO](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO

CA $84

CA $94 total

Jan 29 - Jan 30

includes taxes & fees

6.6/10 (621 reviews)

[](https://expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information)

![Quality Inn Cairo I-57](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Quality Inn Cairo I-57

13201 Kessler Road Cairo IL

CA $107

CA $119 total

Jan 30 - Jan 31

includes taxes & fees

6.4/10 (275 reviews)

[](https://expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information)

![Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout.](https://images.trvl-media.com/lodging/110000000/109110000/109109100/109109006/bd476bf3_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout.

 Tamms IL

[Get rates](https://expedia.ca/Hotel-Search?startDate=11%2F02%2F2026&endDate=12%2F02%2F2026&selected=109109006&PinnedHotelID=109109006&HadPinnedHotel=true&regionId=6626)

9.8/10 Exceptional! (24 reviews)

[](https://expedia.ca/Tamms-Hotels-Attention-Hunters-Deer-Camp.h109109006.Hotel-Information)

![La Center Motel](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/6218157c_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### La Center Motel

474 W Kentucky Dr La Center KY

[Get rates](https://expedia.ca/Hotel-Search?startDate=11%2F02%2F2026&endDate=12%2F02%2F2026&selected=99665264&PinnedHotelID=99665264&HadPinnedHotel=true&regionId=6626)

7.8/10 Good! (17 reviews)

[](https://expedia.ca/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information)

## Hotels in Cairo with star-rating

![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg)

3 Star Hotels

1 properties

[](https://expedia.ca/3Star-Cairo-Hotels.s30-0-d6626.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg)

2 Star Hotels

6 properties

[](https://expedia.ca/2Star-Cairo-Hotels.s20-0-d6626.Travel-Guide-Filter-Hotels)

## Recent reviews of Cairo hotels

![Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout.](https://images.trvl-media.com/lodging/110000000/109110000/109109100/109109006/bd476bf3_y.jpg)

### Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout.

5/5 Excellent

"Great place to stay for our hunting trip. Host was helpful and very accommodating."

A verified traveller stayed at Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout.

Posted 9 days ago

[](https://expedia.ca/Tamms-Hotels-Attention-Hunters-Deer-Camp.h109109006.Hotel-Information)

![Charming cottage overlooking Lake Acre](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/7bfe8087_y.jpg)

### Charming cottage overlooking Lake Acre

5/5 Excellent

"beautiful solid cabin. Great books on the history of the area. Truly enjoyed are restful stay! I just wish it was warmer, so we could have enjoyed the amazing stars at night and just the beauty of the area. We would rent again."

A verified traveller from Harvard stayed at Charming cottage overlooking Lake Acre

Posted 9 days ago

[](https://expedia.ca/Charming-Cabin-Overlooking-5-Acre-Lake.h39671140.Hotel-Information)

![Charming 3-bedroom house near ball park in quiet neighborhood](https://images.trvl-media.com/lodging/107000000/106630000/106623200/106623184/8a1aff87_y.jpg)

### Charming 3-bedroom house near ball park in quiet neighborhood

5/5 Excellent

"This was our second time staying at this property. Everything was clean and just as advertised. We especially love the nice little touches to make this feel like home away from home for the night that we were there. The host was a great communicator. The check-in process was smooth."

A verified traveller stayed at Charming 3-bedroom house near ball park in quiet neighborhood

Posted 2 weeks ago

[](https://expedia.ca/Bardwell-Hotels-Charming-3-Bedroom-House-Near-Ball-Park-In-Quiet-Neighborhood.h106623184.Hotel-Information)

![Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286](https://images.trvl-media.com/lodging/54000000/53860000/53856300/53856204/f8ac9a8a_y.jpg)

### Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

5/5 Excellent

"We loved our stay in this country location. It was quiet and peaceful yet close enough to Paducah for shopping and restaurants. The home was spotless, and every amenity was available - basic kitchen supplies (mixer, oil, sugar, spices, and much more), lots of towels and blankets and pillows, wifi and TV, washer and dryer, and more I'm probably not thinking of.It was very cold and snowy during our visit, so we made the home a cozy place to watch movies and relax. We even had our three small dogs with us, and there was lots of yard space to walk them.If you visit here, don't miss the National Quilt Museum. It's not your grandmother's quilt - it's amazing fabric art! Oh, and we found a vegan restaurant we liked: Branch Out.Definitely recommend staying here!!!"

A verified traveller from Godfrey, IL, USA stayed at Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Posted 2 months ago

[](https://expedia.ca/Quiet-Home-On-Horse-Farm.h53856204.Hotel-Information)

![Cozy cabins on beautiful Horseshoe Lake](https://images.trvl-media.com/lodging/91000000/90340000/90331200/90331191/53db6388_y.jpg)

### Cozy cabins on beautiful Horseshoe Lake

5/5 Excellent

"The cabin was great"

A verified traveller stayed at Cozy cabins on beautiful Horseshoe Lake

Posted 2 months ago

[](https://expedia.ca/Cozy-Cabins-On-Beautiful-Horseshoe-Lake.h90331191.Hotel-Information)

![Super 8 by Wyndham Charleston/Sikeston East MO](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39_y.jpg)

### Super 8 by Wyndham Charleston/Sikeston East MO

5/5 Excellent

"Thank you "

A verified traveller stayed at Super 8 by Wyndham Charleston/Sikeston East MO

Posted 3 months ago

[](https://expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information)

![The Rested Duck Mallard Room](https://images.trvl-media.com/lodging/91000000/90340000/90331100/90331048/29d5afe7_y.jpg)

### The Rested Duck Mallard Room

5/5 Excellent

"It was fine. It was fairly clean and the bed was comfortable. No where to put anything down in the bathroom. "

A verified traveller stayed at The Rested Duck Mallard Room

Posted 4 months ago

[](https://expedia.ca/The-Rested-Duck-Mallard-Room.h90331048.Hotel-Information)

![Peaceful secluded cabin located near Horseshoe Lake ](https://images.trvl-media.com/lodging/110000000/109740000/109730100/109730068/b6736ddb_y.jpg)

### Peaceful secluded cabin located near Horseshoe Lake 

5/5 Excellent

"The cabin is perfect for a quiet getaway. Location is great close to Dollar General, gas station and restaurants"

A verified traveller stayed at Peaceful secluded cabin located near Horseshoe Lake 

Posted 4 months ago

[](https://expedia.ca/Peaceful-Secluded-Cabin-Located-Near-Horseshoe-Lake.h109730068.Hotel-Information)

![Quality Inn Cairo I-57](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d_y.jpg)

### Quality Inn Cairo I-57

5/5 Excellent

"Break fast was excellent "

A verified traveller stayed at Quality Inn Cairo I-57

Posted 4 months ago

[](https://expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information)

## Frequently asked questions

### What are the best budget hotels in Cairo?

### When is the best time to go to Cairo?

> As you venture into the peak season from March to May, you'll find an increase in tourist activity, with visitors flocking to iconic landmarks such as the Pyramids of Giza and the Egyptian Museum. The warm weather and clear skies provide an excellent backdrop for sightseeing, ensuring that you can fully appreciate the rich history and stunning architecture that Cairo has to offer.
> 
>   
> For those who appreciate a more tranquil atmosphere while still enjoying the city's attractions, consider planning your visit in November. During this time, you may find fewer crowds, allowing for a more intimate experience as you explore Cairo's treasures at a leisurely pace.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Cairo hotel booking with Expedia?

### How much is the nightly rate at a Cairo hotel?

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- [Visit Johnson County ](https://www.expedia.ca/Johnson-County.dx553248635976430348)
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- [Superman Statue ](https://www.expedia.ca/Superman-Statue-Metropolis.d6161415.Vacation-Attraction)
- [Visit Vienna ](https://www.expedia.ca/Vienna.dx56022)

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