Title: The 10 Best Hotels Near Fort Defiance State Park, Cairo from CA $92 | Expedia.ca [Vacation Rentals in Cairo](https://expedia.ca/Cairo-Vacation-Rentals.d6626.Travel-Guide-VacationRentals)[Flights to Cairo](https://expedia.ca/Cheap-Flights-To-Cairo.d6626.Travel-Guide-Flights)[Fort Defiance State Park Car Rentals](https://expedia.ca/Car-Rentals-In-Fort-Defiance-State-Park.d6091411.Car-Rental-Guide)[Fort Defiance State Park Vacations](https://expedia.ca/Fort-Defiance-State-Park-Cairo.d6091411.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels near Fort Defiance State Park, Cairo from CA $92 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 13 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6091411&startDate=2025-12-13&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 14 - Dec 15](https://www.expedia.ca/Hotel-Search?regionId=6091411&startDate=2025-12-14&endDate=2025-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6091411&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6091411&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Fort Defiance State Park hotels ![Basic Double Room](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/6218157c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Double Room](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/1016c5b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/520db902.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/bbe54b21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Center Motel [](https://www.expedia.ca/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information) 17.5 km from Fort Defiance State Park 7.8/10 Good (16) "The place was very clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Victoria [](https://www.expedia.ca/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information) ![Desk, iron/ironing board, free WiFi, alarm clocks](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/228b486a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/d436dcb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/2b61a8ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/ec6ce079.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eagle Inn Charleston [](https://www.expedia.ca/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) 16.2 km from Fort Defiance State Park 6.8/10 (103) "Middle of nowhere hotel was ok" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $83 CA $92 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/d2862bfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/94d9e92f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/074a1dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/cde4423c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Charleston - Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn-Charleston-I-57.h20594.Hotel-Information) 20.2 km from Fort Defiance State Park 6.8/10 (406) "The staff was very friendly and accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arturo CA $90 CA $100 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn-Charleston-I-57.h20594.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/a5038447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/1ca277a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Charleston/Sikeston East MO [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) 17.5 km from Fort Defiance State Park 6.6/10 (612) "Staff was great! Room was nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lana CA $86 CA $95 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/c71a6d1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/0feda7c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/f1c41457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cairo I-57 [](https://www.expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) 7.8 km from Fort Defiance State Park 6.6/10 (273) "Break fast was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Uma CA $101 CA $112 total includes taxes & fees Jan 10 - Jan 11, 2026 [](https://www.expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-27&endDate=2025-12-28®ionId=6091411&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Fort Defiance State Park Hotel Reviews ![Drury Inn & Suites Paducah](https://images.trvl-media.com/lodging/1000000/50000/42500/42450/w3837h2560x3y0-d7f24a86_y.jpg) ### Drury Inn & Suites Paducah 10/10 Excellent "Very friendly staff. Great breakfast/ dinner. I liked the Kickback room. The bed was comfortable. " [](https://expedia.ca/Paducah-Hotels-Drury-Inn-Suites-Paducah.h42450.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Clean room and spacious " [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Drury Inn Paducah](https://images.trvl-media.com/lodging/1000000/50000/42500/42447/2d58db7a_y.jpg) ### Drury Inn Paducah 10/10 Excellent "Very nice hotel. Room is spacious and so is the bathroom and staff was very nice. Breakfast and dinner buffets were pretty good too. Will be my new padukah hotel for sure " [](https://expedia.ca/Paducah-Hotels-Drury-Inn-Paducah.h42447.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg) ### Days Inn and Suites by Wyndham Sikeston 10/10 Excellent "Very nice room, staff was nice. The tv room and bathroom were cold. No heat in those rooms." [](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston 10/10 Excellent "Easy parking , quiet and comfortable bed , we’ll stop again on our way back " [](https://expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286](https://images.trvl-media.com/lodging/54000000/53860000/53856300/53856204/f8ac9a8a_y.jpg) ### Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286 10/10 Excellent "We loved our stay in this country location. It was quiet and peaceful yet close enough to Paducah for shopping and restaurants. The home was spotless, and every amenity was available - basic kitchen supplies (mixer, oil, sugar, spices, and much more), lots of towels and blankets and pillows, wifi and TV, washer and dryer, and more I'm probably not thinking of.It was very cold and snowy during our visit, so we made the home a cozy place to watch movies and relax. We even had our three small dogs with us, and there was lots of yard space to walk them.If you visit here, don't miss the National Quilt Museum. It's not your grandmother's quilt - it's amazing fabric art! Oh, and we found a vegan restaurant we liked: Branch Out.Definitely recommend staying here!!!" [](https://expedia.ca/Quiet-Home-On-Horse-Farm.h53856204.Hotel-Information) ![Country Yard Inn and Suite](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7b36182_y.jpg) ### Country Yard Inn and Suite 10/10 Excellent "Great stay, numerous tv movie channels, check in easy, friendly staff" [](https://expedia.ca/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) ![Pear Tree Inn Sikeston](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg) ### Pear Tree Inn Sikeston 10/10 Excellent "This is our go to when we visit relatives" [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Comfort Suites](https://images.trvl-media.com/lodging/78000000/77980000/77979800/77979726/771d9df8_y.jpg) ### Comfort Suites 10/10 Excellent "Always a great stay at this property. " [](https://expedia.ca/Paducah-Hotels-Comfort-Suites.h77979726.Hotel-Information) ## Hotels near other Fort Defiance State Park attractions ### Columbus-Belmont State Park 3.7/5 (18 reviews) You can learn about the history of Columbus with a stop at Columbus-Belmont State Park. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6091579) ### Ullin City Hall After visiting Ullin City Hall, make a plan to see the other sights and activities in Ullin. Amble around the area's parks or experience its museums. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6187204) ### Limekin Springs Trail Trailhead You can take time to visit Limekin Springs Trail Trailhead during your travels to Ullin. Make some time to visit the shops while you're in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=641530566247731200) ### Front Street Studio & Art Gallery 4.2/5 (9 reviews) You can spend time browsing the exhibits at Front Street Studio & Art Gallery during your travels in Blodgett. While in this relaxing area, you can savor the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655753) ### Lower Cache River Access Area You can take time to visit Lower Cache River Access Area during your travels to Cypress. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=877134620821561344) ### City of Miner Convention Center Learn about the events happening at City of Miner Convention Center during your trip to Miner. While in this relaxing area, you can savor the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=818566100963352576) ### Henry N Barkhausen Cache River Wetlands Center You can spend time studying the exhibits at Henry N Barkhausen Cache River Wetlands Center during your travels in Cypress. Amble around the area's parks or experience its museums. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655797) ## Frequently asked questions ### What's the area like around Fort Defiance State Park? ### What's the best place to stay close to Fort Defiance State Park? ### If I need to cancel the hotel reservation for my stay near Fort Defiance State Park, will I receive a refund? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [3 Star Hotels in West Vienna ](https://www.expedia.ca/3Star-West-Vienna-Hotels.s30-0-d553248635975864465.Travel-Guide-Filter-Hotels) - [Alto Pass Hotels ](https://www.expedia.ca/Alto-Pass-Hotels.d73449.Travel-Guide-Hotels) - [Anna Hotels ](https://www.expedia.ca/Anna-Hotels.d6406.Travel-Guide-Hotels) - [Farmstay in Belknap ](https://www.expedia.ca/Belknap-Agritourism.d3000346121-aaAgritourism.Travel-Guide-Accommodation) - [Belknap Hotels ](https://www.expedia.ca/Belknap-Hotels.d3000346121.Travel-Guide-Hotels) - [Bloomfield Hotels ](https://www.expedia.ca/Bloomfield-Hotels.d553248635975848050.Travel-Guide-Hotels) - 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