
Find hotels near Fort Defiance State Park, Cairo from CA $88
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Our top choices for Fort Defiance State Park hotels

Quality Inn Cairo I-57
Quality Inn Cairo I-577.8 km from Fort Defiance State Park
6.6 out of 10, (282 reviews)
The price is CA $99
CA $110 total
includes taxes & fees
Mar 31 - Apr 1

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO17.5 km from Fort Defiance State Park
6.8 out of 10, (626 reviews)
The price is CA $85
CA $95 total
includes taxes & fees
Mar 26 - Mar 27

The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-Sikeston20.2 km from Fort Defiance State Park
6.8 out of 10, (409 reviews)
The price is CA $79
CA $88 total
includes taxes & fees
Mar 31 - Apr 1

Eagle Inn Charleston
Eagle Inn Charleston16.2 km from Fort Defiance State Park
6.6 out of 10, (105 reviews)
The price is CA $88
CA $97 total
includes taxes & fees
Mar 26 - Mar 27

La Center Motel
La Center Motel17.5 km from Fort Defiance State Park
7.6 out of 10, Good, (18 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to Fort Defiance State Park
Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Quality Inn Cairo I-57 | 6.6 282 reviews | View | ||||||
![]() Super 8 by Wyndham Charleston/Sikeston East MO | 6.8 626 reviews | View | ||||||
![]() The Riverstone Hotel Charleston-Sikeston | 6.8 409 reviews | View | ||||||
![]() Eagle Inn Charleston | 6.6 105 reviews | View | ||||||
![]() La Center Motel | 7.6 Good 18 reviews | View |
Top Fort Defiance State Park Hotel Reviews

Drury Inn & Suites Paducah
10/10 Excellent
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