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Find Family Hotels in Cairo, IL from CA $92

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Check availability on Cairo Family Hotels

Tonight
Aug 14 - Aug 15
Tomorrow
Aug 15 - Aug 16
This weekend
Aug 14 - Aug 16
Next weekend
Aug 21 - Aug 23

Our top choices for Cairo family-friendly hotels

1. Quality Inn Cairo I-57

Quality Inn Cairo I-57
Cairo
  • Quiet family comfort with free breakfast and modern amenities along the Mississippi River makes this hotel perfect for stress-free trips.
CA $100
CA $111 total
includes taxes & fees
Aug 22 - Aug 23
Quality Inn Cairo I-57

2. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
Charleston
  • Unleash family fun in Charleston with premium TV channels, pay movies, and free cribs, all while friendly staff elevate your stay.
CA $83
CA $92 total
includes taxes & fees
Aug 16 - Aug 17
Super 8 by Wyndham Charleston/Sikeston East MO

3. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
Charleston
  • Kids stay active and happy with free activities, family-friendly rooms, and morning meals at this welcoming Charleston hotel.
CA $93
CA $103 total
includes taxes & fees
Sep 7 - Sep 8
The Riverstone Hotel Charleston-Sikeston
View all properties

Choose what matters most at family-friendly hotels in Cairo

Breakfast included
Pool
All-inclusive
4 stars
5 stars

Top Cairo Hotel Reviews

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

8/10 Good
"The ad and picture for the hotel is a little deceiving. It shows a large fountain in front of the front lobby. There was none. This is the former Quality Inn Hotel was not good at all. The hotel has been cleaned up and rebranded. The room was nice. My only concern was all the bugs that were outside the room door and flew into the room when you opened your door at night. The other thing that I did not like was the surprise $100 fee that I had to pay up front for potential damage to the room. This fee was returned during check out."
James 2-night trip
Posted 4 days ago
The Riverstone Hotel Charleston-Sikeston
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

10/10 Excellent
"Nice staff. Very accommodating."
Domingo 1-night trip
Posted 5 days ago
Super 8 by Wyndham Charleston/Sikeston East MO

Frequently asked questions

What's Cairo like for family-friendly vacations?
You might want to consider the historic destination of Cairo if you've been thinking about a trip for the whole family. The entertainment, restaurants, and libraries are just a few things that make this an attractive spot for a family vacation. Arrange a flight into Cairo, IL (CIR-Cairo Regional), which is the closest airport, or Paducah, KY (PAH-Barkley Regional), which is located 22.9 mi (36.8 km) from the city center.
What's the best hotel for a family vacation to Cairo?
Quality Inn Cairo I-57 is a hotel with free parking and free breakfast, and it's a top choice on Expedia for families.
When's the best time to book a family-friendly vacation in Cairo?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.
What's there to see and do with your family in Cairo?
While you and the family are vacationing in Cairo, you might want to get outside and enjoy the great outdoors at spots such as Mississippi River, Ohio River Valley, and Shawnee National Forest. Make sure you have time to check out activities like Ohio River and Fort Defiance State Park.

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