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Our top choices for Byron hotels

1. Comfort Inn & Suites West - Medical Center
Comfort Inn & Suites West - Medical CenterRochester
8.8 out of 10, Excellent, (668 reviews)
The price is CA $113
CA $130 total
includes taxes & fees
Nov 28 - Nov 29

2. Sleep Inn & Suites West-Near Medical Center
Sleep Inn & Suites West-Near Medical CenterRochester
9.0 out of 10, Wonderful, (726 reviews)
The price is CA $107
CA $123 total
includes taxes & fees
Nov 28 - Nov 29

3. Baymont by Wyndham Kasson Rochester Area
Baymont by Wyndham Kasson Rochester AreaKasson
6.6 out of 10, (424 reviews)
The price is CA $92
CA $99 total
includes taxes & fees
Nov 22 - Nov 23

4. Staybridge Suites Rochester - Commerce Dr NW by IHG
Staybridge Suites Rochester - Commerce Dr NW by IHGRochester
8.8 out of 10, Excellent, (577 reviews)
The price is CA $146
CA $168 total
includes taxes & fees
Nov 22 - Nov 23

5. Hampton Inn & Suites Rochester-North
Hampton Inn & Suites Rochester-NorthRochester
9.2 out of 10, Wonderful, (1,002 reviews)
The price is CA $137
CA $157 total
includes taxes & fees
Nov 14 - Nov 15

6. Quality Inn near Medical Center
Quality Inn near Medical CenterRochester
7.8 out of 10, Good, (988 reviews)
The price is CA $88
CA $102 total
includes taxes & fees
Nov 29 - Nov 30

7. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Microtel Inn & Suites by Wyndham Rochester North Mayo ClinicRochester
7.8 out of 10, Good, (1,002 reviews)
The price is CA $98
CA $112 total
includes taxes & fees
Nov 9 - Nov 10

8. TownePlace Suites by Marriott Rochester
TownePlace Suites by Marriott RochesterRochester
8.8 out of 10, Excellent, (622 reviews)
The price is CA $137
CA $158 total
includes taxes & fees
Nov 15 - Nov 16

9. Extended Stay America Suites Rochester North
Extended Stay America Suites Rochester NorthRochester
7.6 out of 10, Good, (746 reviews)
The price is CA $90
CA $103 total
includes taxes & fees
Nov 9 - Nov 10

10. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHGKutzky Park
8.6 out of 10, Excellent, (849 reviews)
The price is CA $143
CA $164 total
includes taxes & fees
Nov 14 - Nov 15

11. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. MarysKutzky Park
9.6 out of 10, Exceptional, (751 reviews)
The price is CA $151
CA $174 total
includes taxes & fees
Nov 13 - Nov 14

12. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Best Western Rochester Hotel Mayo Clinic Area/St. Mary'sRochester
8.2 out of 10, Very good, (1,000 reviews)
The price is CA $139
CA $160 total
includes taxes & fees
Nov 15 - Nov 16

13. Willow Inn Suites Rochester
Willow Inn Suites RochesterRochester
6.8 out of 10, (15 reviews)
The price is CA $88
CA $102 total
includes taxes & fees
Nov 8 - Nov 9

14. Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic AreaDowntown Rochester
9.0 out of 10, Wonderful, (1,001 reviews)
The price is CA $156
CA $179 total
includes taxes & fees
Nov 28 - Nov 29

15. EVEN Hotel Rochester - Mayo Clinic Area by IHG
EVEN Hotel Rochester - Mayo Clinic Area by IHGKutzky Park
9.4 out of 10, Exceptional, (1,012 reviews)
The price is CA $154
CA $196 total
includes taxes & fees
Nov 27 - Nov 28

16. Econo Lodge Mayo Clinic Area
Econo Lodge Mayo Clinic AreaRochester
9.0 out of 10, Wonderful, (1,005 reviews)
The price is CA $96
CA $111 total
includes taxes & fees
Dec 4 - Dec 5

17. Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic AreaKutzky Park
7.8 out of 10, Good, (1,054 reviews)
The price is CA $103
CA $118 total
includes taxes & fees
Dec 8 - Dec 9

18. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic AreaHistoric Southwest
8.6 out of 10, Excellent, (1,006 reviews)
The price is CA $160
CA $184 total
includes taxes & fees
Nov 14 - Nov 15

19. Home2 Suites by Hilton Rochester Mayo Clinic Area
Home2 Suites by Hilton Rochester Mayo Clinic AreaRochester
9.6 out of 10, Exceptional, (1,001 reviews)
The price is CA $154
CA $177 total
includes taxes & fees
Nov 29 - Nov 30

20. Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHGRochester
8.8 out of 10, Excellent, (1,000 reviews)
The price is CA $121
CA $139 total
includes taxes & fees
Nov 14 - Nov 15
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Byron attractions
Top Byron Hotel Reviews

Sleep Inn & Suites West-Near Medical Center
Sleep Inn & Suites West-Near Medical CenterRochester


















































































