Title: Book The Best Hotels in Byron, MN for 2025 from CA $88 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Byron](https://expedia.ca/Byron-Vacation-Rentals.d553248623858895563.Travel-Guide-VacationRentals)[Byron Car Rentals](https://expedia.ca/Car-Rentals-In-Byron.d553248623858895563.Car-Rental-Guide)[Byron Vacation Packages](https://expedia.ca/Byron.d553248623858895563.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Byron, MN from CA $88 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Byron Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America®ionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2025-12-05&d1=2025-12-05&endDate=2025-12-07&d2=2025-12-07&travelerType=family_friendly) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America®ionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2025-12-05&d1=2025-12-05&endDate=2025-12-07&d2=2025-12-07&lodging=APARTMENT) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America®ionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2025-12-05&d1=2025-12-05&endDate=2025-12-07&d2=2025-12-07&amenities=HOT_TUB) Pool [](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America®ionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2025-12-05&d1=2025-12-05&endDate=2025-12-07&d2=2025-12-07&amenities=POOL) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America®ionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2025-12-05&d1=2025-12-05&endDate=2025-12-07&d2=2025-12-07&amenities=PETS) ## Check prices for these dates Tonight [Nov 21 - Nov 22](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2025-11-21&endDate=2025-11-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 22 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2025-11-22&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 381 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms | Living area](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/45535621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/f91e65d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/ecda08e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Grand Hotel Downtown Rochester 8.2/10 Very good (1763) "Great hotel close to everything convenient location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marta CA $176 CA $203 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/055a808d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/231bcb83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/37e2c033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Mayo Clinic Area Rochester 9.0/10 Wonderful (881) "Good breakfast..shuttle service is excellent..super nice staff.." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DALE K CA $89 CA $102 total includes taxes & fees Dec 12 - Dec 13 [](https://www.expedia.ca/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) ![Serves lunch, dinner, and happy hour](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/3b0f1e42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/3bd995bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/493f76e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Rochester Near Mayo Clinic Rochester 8.2/10 Very good (1116) "Was great for a stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) eric CA $103 CA $118 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/daff149b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/dd818bd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's pool](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/f69df08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S Rochester 7.2/10 Good (1021) "Clean room and very courteous staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Harlan CA $96 CA $110 total includes taxes & fees Nov 25 - Nov 26 [](https://www.expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/bac0b2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/3613a59b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/eabb718a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG Kutzky Park 9.4/10 Exceptional (942) "Hotel was spotless, excellent staff and the breakfast was excellent. Late night eats at the restaurant and the food served was fantastic." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carmino CA $123 CA $144 total includes taxes & fees Nov 28 - Nov 29 [](https://www.expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/7b237c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/10494388.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/13abbe0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aspen Suites Rochester 9.0/10 Wonderful (680) "Excellent service excellent accommodations. I will stay here again when I come next time." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ryan [](https://www.expedia.ca/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/1b6617d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/0c1d91fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/43d012a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/7f2ecd4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic Rochester 7.8/10 Good (1004) "Rooms where very neet and tidy , breakfast was decent and the price was quite a value point " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard CA $90 CA $103 total includes taxes & fees Dec 12 - Dec 13 [](https://www.expedia.ca/Rochester-Hotels-Microtel-Inn-Suites-By-Wyndham-Rochester-North-Mayo-Clinic.h116574.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/42f521a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/f4426c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/bd0b7bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG Downtown Rochester 8.8/10 Excellent (868) "Great room and stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trevor CA $112 CA $128 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/6da96ba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking (Ground Floor)](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/46eaeea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/bab1f0e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/f6a03fe3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Rochester Mayo Clinic Area Rochester 7.8/10 Good (1007) "Great Stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aweng CA $77 CA $88 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Rochester-Hotels-Super-8-By-Wyndham-Rochester-Mayo-Clinic-Area.h25164.Hotel-Information) ![Coffee service](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/5f8bd693.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/8cbdee80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/03c26c35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/c5b39a44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MainStay Suites Rochester South Mayo Clinic Rochester 7.0/10 Good (85) "Staff is friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Merry CA $80 CA $92 total includes taxes & fees Dec 12 - Dec 13 [](https://www.expedia.ca/Rochester-Hotels-Extended-Stay-America-Suites-Rochester-South.h846574.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/00ce891c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/fce6cfb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/34563649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Rochester South Rochester 9.4/10 Exceptional (279) "Staff was nice and rooms are nice!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shelly CA $97 CA $111 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/39da8a7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/4db52fa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/bdf57892.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/222c4dee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys Kutzky Park 8.6/10 Excellent (923) "This is a convenient place to stay when visiting Mayo." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Faith CA $132 CA $153 total includes taxes & fees Dec 12 - Dec 13 [](https://www.expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/92dc90b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/c5c5f3cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/31690353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/fca8e68c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aspen Select Rochester 8.4/10 Very good (1003) "Safe parking very clean and breakfast had options for anyone" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cindy [](https://www.expedia.ca/Rochester-Hotels-Aspen-Select.h12245240.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/c3584a83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/28d8dcf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/937e22b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/63ec118a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites Rochester South Mayo Clinic Rochester 8.4/10 Very good (1004) "Clean room, fun staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $119 CA $137 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h455558.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/910000/906700/906635/f81bde8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/910000/906700/906635/1cd9a36e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/1000000/910000/906700/906635/ef0be254.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/910000/906700/906635/daa559a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Kasson Rochester Area Kasson 6.6/10 (368) "We did not use the pool or the hot tub but loved it! Staff was very nice, rooms were clean and easy to access. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Breanna CA $84 CA $90 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Rochester-Hotels-Baymont-By-Wyndham-Kasson-Rochester-Area.h906635.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/bde7ad17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/7b075080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/d3281bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/745c7377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Rochester Mayo Clinic Area South Rochester 9.6/10 Exceptional (237) "Nice big room-big walk in showet" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tammy CA $154 CA $177 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area-South.h90610605.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/76e6edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/fe70c541.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/5419eb23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/19467991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Rochester Mayo Clinic Area Rochester 7.0/10 Good (714) "Great place to stay close to places needed" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amber CA $85 CA $98 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Rochester-Hotels-Baymont-By-Wyndham-Rochester-Mayo-Clinic-Area.h459763.Hotel-Information) ![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/b33056f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/4b144b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/w3000h3995x0y0-7bb98679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/0647340c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area Historic Southwest 8.6/10 Excellent (1009) "If you are going to Mayo Clinic, this is a great place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eileen CA $173 CA $199 total includes taxes & fees Nov 25 - Nov 26 [](https://www.expedia.ca/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) ![Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room)](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2555x4y4-921fa2b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room)](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/ec5f8616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3837h2560x3y0-014e984a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's Rochester 8.2/10 Very good (776) "Great place to stay. Freindly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) joel CA $132 CA $152 total includes taxes & fees Nov 25 - Nov 26 [](https://www.expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![2 indoor pools](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/821fc05d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Arcade](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/ced48756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/f8e4d672.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Med City Inn & Suites - Mayo Clinic Area Kutzky Park 7.8/10 Good (1006) "Great staff, room was clean and location was great for our needs." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tim CA $101 CA $117 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-06®ionId=553248623858895563&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FByron-Hotels.d553248623858895563.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FByron-Hotels.d553248623858895563.Travel-Guide-Hotels) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Limited-time deals: save up to 50% on select hotels [Book now](https://expedia.ca/deals?rfrr=HTG_BF_PROMO_553248623858895563) ### Stay near popular Byron attractions [](https://expedia.ca/Oxbow-Park-Hotels.0-l6308341-0.Travel-Guide-Filter-Hotels) #### Oxbow Park Explore the great outdoors at Oxbow Park, a lovely green space in Byron. Check out the top-notch restaurants or charming coffeehouses in this walkable area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6308341) ## More cheap stays in Byron ![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Rochester-South 1755 S Broadway Rochester MN CA $115 CA $132 total Dec 22 - Dec 23 includes taxes & fees 9/10 Wonderful! (1,017 reviews) [](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Brentwood Inn & Suites 123 Fourth Ave. NW Rochester MN CA $158 CA $182 total Nov 25 - Nov 26 includes taxes & fees 8.6/10 Excellent! (1,008 reviews) [](https://expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/821fc05d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Med City Inn & Suites - Mayo Clinic Area 435 16th Ave Nw Rochester MN CA $101 CA $117 total Nov 23 - Nov 24 includes taxes & fees 7.8/10 Good! (1,005 reviews) [](https://expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Econo Lodge Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Econo Lodge Mayo Clinic Area 1850 S Broadway Rochester MN CA $89 CA $102 total Dec 12 - Dec 13 includes taxes & fees 9/10 Wonderful! (875 reviews) [](https://expedia.ca/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) ![Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/1b6617d7_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic 4210 Highway 52 North Rochester MN CA $90 CA $103 total Dec 12 - Dec 13 includes taxes & fees 7.8/10 Good! (1,000 reviews) [](https://expedia.ca/Rochester-Hotels-Microtel-Inn-Suites-By-Wyndham-Rochester-North-Mayo-Clinic.h116574.Hotel-Information) ![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's 1517 16th St Sw Rochester MN CA $132 CA $152 total Nov 25 - Nov 26 includes taxes & fees 8.2/10 Very Good! (776 reviews) [](https://expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ## Hotels in Byron with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 2 properties [](https://expedia.ca/4Star-Byron-Hotels.s40-0-d553248623858895563.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 42 properties [](https://expedia.ca/3Star-Byron-Hotels.s30-0-d553248623858895563.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 37 properties [](https://expedia.ca/2Star-Byron-Hotels.s20-0-d553248623858895563.Travel-Guide-Filter-Hotels) ## Recent reviews of Byron hotels ![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg) ### Brentwood Inn & Suites 5/5 Excellent "Very easy access to Mayo facility" A verified traveller stayed at Brentwood Inn & Suites Posted 5 hours ago [](https://expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/b33056f7_y.jpg) ### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area 5/5 Excellent "Excellent facility. Wonderful people!" A verified traveller stayed at Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area Posted 19 hours ago [](https://expedia.ca/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) ![Spark by Hilton Rochester South](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg) ### Spark by Hilton Rochester South 5/5 Excellent "Yes the room was clean and the staff was very curious." A verified traveller stayed at Spark by Hilton Rochester South Posted 20 hours ago [](https://expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![AmericInn by Wyndham Rochester Near Mayo Clinic](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg) ### AmericInn by Wyndham Rochester Near Mayo Clinic 5/5 Excellent "nice and quiet, no problems" A verified traveller stayed at AmericInn by Wyndham Rochester Near Mayo Clinic Posted 21 hours ago [](https://expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 5/5 Excellent "Because Expedia's calendars indicates days rather than nights, what I thought was a reservation for 3 nights was a reservation for 2 nights and three days, so I had to book a room for an additional night. The staff was very helpful in letting us stay in the same room for that third night." A verified traveller stayed at La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S Posted 1 day ago [](https://expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 5/5 Excellent "Everything was as expected . Nice tidy unit" A verified traveller from Lake Geneva stayed at Kahler Grand Hotel Posted 2 days ago [](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Hilton Garden Inn Rochester Downtown, MN](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/67ee8968_y.jpg) ### Hilton Garden Inn Rochester Downtown, MN 5/5 Excellent "The valet parking is helpful. " A verified traveller stayed at Hilton Garden Inn Rochester Downtown, MN Posted 2 days ago [](https://expedia.ca/Rochester-Hotels-Hilton-Garden-Inn-Rochester-Downtown.h214679.Hotel-Information) ![Hyatt House Rochester/Mayo Clinic Area](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/369065b1_y.jpg) ### Hyatt House Rochester/Mayo Clinic Area 5/5 Excellent "Clean, staff is friendly no complaints " A verified traveller from Maple Grove stayed at Hyatt House Rochester/Mayo Clinic Area Posted 2 days ago [](https://expedia.ca/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information) ![EVEN Hotel Rochester - Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_y.jpg) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG 5/5 Excellent "The most important thing for me is how spacious and clean the rooms and the hotel are. " A verified traveller stayed at EVEN Hotel Rochester - Mayo Clinic Area by IHG Posted 3 days ago [](https://expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ## Frequently asked questions ### When is the best time to go to Byron? > The most popular time to visit Byron Bay is during the warm summer months of December to February. With average temperatures ranging from 25 to 30°C, this period is great for beach lovers and adventure seekers alike. The sunny weather creates an friendly space for outdoor activities, whether you're surfing the waves, relaxing on the beach, or exploring the stunning coastal walks. > > > > During the peak season from December to January, Byron Bay buzzes with vibrant tourist activity. The festive spirit is palpable as visitors flock to the area, drawn by its stunning beaches, world-class dining, and lively festivals. It's a fantastic time to immerse yourself in the local culture, with events showcasing music, art, and culinary delights that make Byron Bay a unique destination. > > > > For those who enjoy a more tranquil experience, consider visiting in September or October. This is when the crowds begin to thin out, yet the climate remains pleasantly warm, with temperatures typically around 23 to 27°C. This shoulder season allows for a more relaxed exploration of the area's natural beauty and attractions, all while still enjoying good weather for outdoor pursuits like hiking in the nearby national parks. > > > > Families and couples alike will find plenty of opportunities to create lasting memories in Byron Bay, from dolphin watching to indulging in relaxing spa treatments. The laid-back vibe and emphasis on quality experiences ensure that every visitor can find something to suit their tastes. ### Can I cancel my hotel reservation on Expedia? > You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Byron. ### How can I save on a Byron hotel booking with Expedia? > Members always get our best prices. Find our best Byron hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings. ### How much is the nightly rate at a Byron hotel? > Prices for hotels in Byron often vary, but you can find a great deal from CA $88 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. 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