Title: Book The Best Hotels in Byron, MN for 2026 from CA $96 - Fully Refundable Options - Expedia.ca

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## Go beyond your typical stay in Byron

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America&regionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&amenities=POOL)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America&regionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&travelerType=family_friendly)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America&regionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&amenities=HOT_TUB)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America&regionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&amenities=PETS)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America&regionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&lodging=APARTMENT)

## Check prices for these dates

Tonight

[Feb 6 - Feb 7](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2026-02-06&endDate=2026-02-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 7 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2026-02-07&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Byron hotels

![View from property](https://images.trvl-media.com/lodging/2000000/1090000/1080700/1080618/70cc02f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free full breakfast](https://images.trvl-media.com/lodging/2000000/1090000/1080700/1080618/4e8a78f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pay movies](https://images.trvl-media.com/lodging/2000000/1090000/1080700/1080618/ef35eee8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1090000/1080700/1080618/1c37d6b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Residence Inn by Marriott Rochester Mayo Clinic Area

[](https://www.expedia.ca/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area.h1080618.Hotel-Information)

Downtown Rochester

8.4/10

Very good

(202 reviews)

"Wonderful room, staff, breakfast, and location! Thank you so much!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Olivia

CA $204

CA $234 total

includes taxes & fees

Feb 7 - Feb 8

[](https://www.expedia.ca/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area.h1080618.Hotel-Information)

![Two-Bedroom Apartment - Mobility Accessible/Non-Smoking](https://images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/8523d385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/a8a8ab63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/fa38f94a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor spa tub](https://images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/d89c6321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Broadway Plaza, Trademark Collection by Wyndham

[](https://www.expedia.ca/Rochester-Hotels-Broadway-Plaza.h13173672.Hotel-Information)

Downtown Rochester

9.2/10

Wonderful

(170 reviews)

"Great staff, clean room, spacious kitchen and living room."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

silvia

CA $242

CA $279 total

includes taxes & fees

Feb 7 - Feb 8

[](https://www.expedia.ca/Rochester-Hotels-Broadway-Plaza.h13173672.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/17000000/16120000/16119600/16119557/978fdbcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Concierge desk](https://images.trvl-media.com/lodging/17000000/16120000/16119600/16119557/5b562205.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, individually decorated](https://images.trvl-media.com/lodging/17000000/16120000/16119600/16119557/3144e2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business centre](https://images.trvl-media.com/lodging/17000000/16120000/16119600/16119557/c5ed6677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Towers At Kahler Grand Hotel

[](https://www.expedia.ca/Rochester-Hotels-The-Towers-At-Kahler-Grand-Hotel.h16119557.Hotel-Information)

Downtown Rochester

9.4/10

Exceptional

(96 reviews)

"Excellent accommodations, amazing staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shannon

CA $553

CA $637 total

includes taxes & fees

Feb 7 - Feb 8

[](https://www.expedia.ca/Rochester-Hotels-The-Towers-At-Kahler-Grand-Hotel.h16119557.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1270000/1263400/1263391/b39d1efa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/2000000/1270000/1263400/1263391/e31f1fad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1270000/1263400/1263391/59be254c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed](https://images.trvl-media.com/lodging/2000000/1270000/1263400/1263391/288dd4d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

[](https://www.expedia.ca/Rochester-Hotels-Courtyard-By-Marriott-Rochester-Mayo-Clinic-AreaSaint-Marys.h1263391.Hotel-Information)

Kutzky Park

9.2/10

Wonderful

(781 reviews)

"Room was clean and the housekeeping person very helpful and courteous "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dawn

CA $142

CA $164 total

includes taxes & fees

Feb 13 - Feb 14

[](https://www.expedia.ca/Rochester-Hotels-Courtyard-By-Marriott-Rochester-Mayo-Clinic-AreaSaint-Marys.h1263391.Hotel-Information)

![2 indoor pools](https://images.trvl-media.com/lodging/1000000/480000/473100/473100/91eb68fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/480000/473100/473100/0ac076f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/480000/473100/473100/bfbd8805.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/480000/473100/473100/51f9562a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TownePlace Suites by Marriott Rochester

[](https://www.expedia.ca/Rochester-Hotels-TownePlace-Suites-By-Marriott-Rochester.h473100.Hotel-Information)

Rochester

8.8/10

Excellent

(546 reviews)

"My kids really enjoyed the pool, and so did I! Room was nice & clean. Staff were nice. I really appreciated the late checkout. (At least compared to other hotels, 12pm is late!) "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ashley

CA $134

CA $154 total

includes taxes & fees

Feb 16 - Feb 17

[](https://www.expedia.ca/Rochester-Hotels-TownePlace-Suites-By-Marriott-Rochester.h473100.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/11000000/10950000/10947300/10947270/9bad372e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/11000000/10950000/10947300/10947270/39097f3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/11000000/10950000/10947300/10947270/70edacbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/11000000/10950000/10947300/10947270/c8e01189.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

[](https://www.expedia.ca/Rochester-Hotels-Fairfield-Inn-Suites-Rochester-Mayo-Clinic-AreaSt-Marys.h10947270.Hotel-Information)

Kutzky Park

9.6/10

Exceptional

(687 reviews)

"Good place to stay when traveling to Mayo apots"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carolyn

CA $134

CA $154 total

includes taxes & fees

Feb 21 - Feb 22

[](https://www.expedia.ca/Rochester-Hotels-Fairfield-Inn-Suites-Rochester-Mayo-Clinic-AreaSt-Marys.h10947270.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/444e106b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/39073559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, pillowtop beds, minibar](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/560201a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 indoor pools](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/7ee0db4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Home2 Suites by Hilton Rochester Mayo Clinic Area

[](https://www.expedia.ca/Rochester-Hotels-Home2-Suites-By-Hilton-Rochester-Mayo-Clinic-Area.h23512633.Hotel-Information)

Rochester

9.6/10

Exceptional

(909 reviews)

"Staff, room and breakfast were wonderful!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

DeLaine

CA $167

CA $192 total

includes taxes & fees

Feb 12 - Feb 13

[](https://www.expedia.ca/Rochester-Hotels-Home2-Suites-By-Hilton-Rochester-Mayo-Clinic-Area.h23512633.Hotel-Information)

![City view from property](https://images.trvl-media.com/lodging/1000000/10000/4000/3948/50a69e5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/4000/3948/c1a0e9f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/4000/3948/d5f4c6e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/10000/4000/3948/7d048b62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Marriott Rochester Mayo Clinic

[](https://www.expedia.ca/Rochester-Hotels-Marriott-Rochester-Mayo-Clinic.h3948.Hotel-Information)

Downtown Rochester

8.4/10

Very good

(531 reviews)

"it was a fantastic "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paul

CA $258

CA $297 total

includes taxes & fees

Feb 13 - Feb 14

[](https://www.expedia.ca/Rochester-Hotels-Marriott-Rochester-Mayo-Clinic.h3948.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/30000/28200/28184/1f96e8b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28200/28184/d34d65df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Down comforters, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/28200/28184/1a68c6fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Down comforters, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/28200/28184/aaa1bd90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn & Suites Mayo Clinic Area

[](https://www.expedia.ca/Rochester-Hotels-Quality-Inn-Suites-Mayo-Clinic-Area.h28184.Hotel-Information)

Rochester

8.8/10

Excellent

(845 reviews)

"Great stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

William

CA $87

CA $102 total

includes taxes & fees

Feb 21 - Feb 22

[](https://www.expedia.ca/Rochester-Hotels-Quality-Inn-Suites-Mayo-Clinic-Area.h28184.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/5000000/4920000/4913700/4913635/90393dc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/5000000/4920000/4913700/4913635/263c4c74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/5000000/4920000/4913700/4913635/9fcb392a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/5000000/4920000/4913700/4913635/79a3373a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

[](https://www.expedia.ca/Rochester-Hotels-Holiday-Inn-Express-Suites-Rochester-Mayo-Clinic-Area.h4913635.Hotel-Information)

Kutzky Park

8.8/10

Excellent

(774 reviews)

"the staff was friendly and helpful/ and the room was clean/ and good amenities"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

carol

CA $141

CA $163 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Rochester-Hotels-Holiday-Inn-Express-Suites-Rochester-Mayo-Clinic-Area.h4913635.Hotel-Information)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/64f360d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/bdf57892.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/a1482b30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/4db52fa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

[](https://www.expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information)

Kutzky Park

8.6/10

Excellent

(961 reviews)

"Friendly staff, good breakfast."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Missy

CA $122

CA $140 total

includes taxes & fees

Feb 13 - Feb 14

[](https://www.expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/10000000/9820000/9817800/9817734/64ac615f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/10000000/9820000/9817800/9817734/54997db8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Room, 2 Queen Beds](https://images.trvl-media.com/lodging/10000000/9820000/9817800/9817734/1f55a294.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living room](https://images.trvl-media.com/lodging/10000000/9820000/9817800/9817734/44746100.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Red Carpet Inn Rochester

[](https://www.expedia.ca/Rochester-Hotels-Red-Carpet-Inn-Rochester.h9817734.Hotel-Information)

Rochester

7.6/10

Good

(535 reviews)

"Quiet and affordable. Comfortable beds."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amy

[](https://www.expedia.ca/Rochester-Hotels-Red-Carpet-Inn-Rochester.h9817734.Hotel-Information)

![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/bba1b373.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/bd0b7bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/daf1e66a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/f4426c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Indigo Rochester – Mayo Clinic Area by IHG

[](https://www.expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information)

Downtown Rochester

8.8/10

Excellent

(928 reviews)

"Great stay as always! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Misty

CA $130

CA $150 total

includes taxes & fees

Feb 21 - Feb 22

[](https://www.expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information)

![Breakfast served](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/56e8351b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, iron/ironing board](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/37670f4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/a4f912ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, iron/ironing board](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/25614355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Garden Inn Rochester Downtown, MN

[](https://www.expedia.ca/Rochester-Hotels-Hilton-Garden-Inn-Rochester-Downtown.h214679.Hotel-Information)

Downtown Rochester

8.8/10

Excellent

(873 reviews)

"The staff was excellent, the room was clean,would recommend to all our friends"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jan

CA $156

CA $179 total

includes taxes & fees

Feb 13 - Feb 14

[](https://www.expedia.ca/Rochester-Hotels-Hilton-Garden-Inn-Rochester-Downtown.h214679.Hotel-Information)

![Pub](https://images.trvl-media.com/lodging/70000000/69690000/69681200/69681188/ed3fe960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Studio, 1 Double Bed, City View, Corner](https://images.trvl-media.com/lodging/70000000/69690000/69681200/69681188/7a89a125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/70000000/69690000/69681200/69681188/12871cd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/70000000/69690000/69681200/69681188/2f1620a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TownePlace Suites by Marriott Rochester Mayo Clinic Area

[](https://www.expedia.ca/Rochester-Hotels-TownePlace-Suites-By-Marriott-Rochester-Mayo-Clinic-Area.h69681188.Hotel-Information)

Kutzky Park

9.6/10

Exceptional

(494 reviews)

"Staff was very helpful. Room was spacious and beds were very comfortable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lisa

CA $174

CA $200 total

includes taxes & fees

Feb 13 - Feb 14

[](https://www.expedia.ca/Rochester-Hotels-TownePlace-Suites-By-Marriott-Rochester-Mayo-Clinic-Area.h69681188.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/10000000/9480000/9478000/9477908/16fa1f7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/10000000/9480000/9478000/9477908/b9b577f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/10000000/9480000/9478000/9477908/a3f10cf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast area](https://images.trvl-media.com/lodging/10000000/9480000/9478000/9477908/8ba09ac8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn & Suites West - Medical Center

[](https://www.expedia.ca/Rochester-Hotels-Comfort-Inn-Suites-West-Medical-Center.h9477908.Hotel-Information)

Rochester

9.0/10

Wonderful

(544 reviews)

"Staff friendly "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gina

CA $98

CA $113 total

includes taxes & fees

Feb 14 - Feb 15

[](https://www.expedia.ca/Rochester-Hotels-Comfort-Inn-Suites-West-Medical-Center.h9477908.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9130000/9120100/9120037/674459db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/10000000/9130000/9120100/9120037/90603a24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/10000000/9130000/9120100/9120037/50706b4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/10000000/9130000/9120100/9120037/6621aeb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

[](https://www.expedia.ca/Rochester-Hotels-Homewood-Suites-By-Hilton-Rochester-Mayo-Clinic-Area-Saint-Marys.h9120037.Hotel-Information)

Kutzky Park

9.2/10

Wonderful

(493 reviews)

"We have stayed here often in the past year. The staff is so kind. Rooms are extremely comfortable and clean. Breakfast is excellent. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Annie

CA $145

CA $166 total

includes taxes & fees

Feb 14 - Feb 15

[](https://www.expedia.ca/Rochester-Hotels-Homewood-Suites-By-Hilton-Rochester-Mayo-Clinic-Area-Saint-Marys.h9120037.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/18000000/17290000/17289900/17289857/07179e13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/18000000/17290000/17289900/17289857/77b4b77d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/18000000/17290000/17289900/17289857/b9c5b46e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17290000/17289900/17289857/e261cbb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sleep Inn & Suites West-Near Medical Center

[](https://www.expedia.ca/Rochester-Hotels-Sleep-Inn-Suites-West-Near-Medical-Center.h17289857.Hotel-Information)

Rochester

9.0/10

Wonderful

(604 reviews)

"It was a quiet place to stay. The rooms were clean and the staff was polite."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laurie

CA $125

CA $144 total

includes taxes & fees

Feb 12 - Feb 13

[](https://www.expedia.ca/Rochester-Hotels-Sleep-Inn-Suites-West-Near-Medical-Center.h17289857.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/10000000/9420000/9416900/9416882/ecc192a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9420000/9416900/9416882/2a3df201.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, 1 Queen Bed, Kitchen](https://images.trvl-media.com/lodging/10000000/9420000/9416900/9416882/04774547.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9420000/9416900/9416882/443e58f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Staybridge Suites Rochester - Commerce Dr NW by IHG

[](https://www.expedia.ca/Rochester-Hotels-Staybridge-Suites-Rochester-Commerce-Dr-NW.h9416882.Hotel-Information)

Rochester

8.8/10

Excellent

(516 reviews)

"Staff very helpful and friendly. Room clean and spacious for our four adults and a baby."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amanda

CA $162

CA $186 total

includes taxes & fees

Feb 7 - Feb 8

[](https://www.expedia.ca/Rochester-Hotels-Staybridge-Suites-Rochester-Commerce-Dr-NW.h9416882.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/3000000/2830000/2825400/2825336/f5dad376.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/3000000/2830000/2825400/2825336/81eb70a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2830000/2825400/2825336/be898197.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, open 6 AM to midnight, sun loungers](https://images.trvl-media.com/lodging/3000000/2830000/2825400/2825336/2358f135.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Rochester-North

[](https://www.expedia.ca/Rochester-Hotels-Hampton-Inn-Suites-Rochester-North.h2825336.Hotel-Information)

Rochester

9.2/10

Wonderful

(1,000 reviews)

"Good staff great place "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Juan

CA $122

CA $141 total

includes taxes & fees

Mar 8 - Mar 9

[](https://www.expedia.ca/Rochester-Hotels-Hampton-Inn-Suites-Rochester-North.h2825336.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-20&endDate=2026-02-21&regionId=553248623858895563&adults=2&sort=RECOMMENDED&openPlayBack=true)

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## Stay near popular Byron attractions

### Putting Green

Enjoy a round of golf in Byron at Putting Green. Amble around the area's parks or experience its art scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=920055107562086400)

### Kalmar Town Hall

Kalmar Town Hall is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=920055764885118976)

### Oxbow Park

Explore the great outdoors at Oxbow Park, a lovely green space in Byron. Check out the charming coffeehouses or top-notch restaurants in this walkable area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6308341)

### Salem Town Hall

After visiting Salem Town Hall, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=920055730965770240)

### Salem Glen Winery

You can enjoy a tasting or tour at Salem Glen Winery during your travels to Byron. Amble around the area's parks or experience its art scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=873856705639997440)

### Oxbow Nature Center

You can spend time exploring the galleries in Oxbow Nature Center during your trip to Byron. Amble around the area's parks or experience its art scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=920055077637910528)

### Brook Lawn Park

After visiting Brook Lawn Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=920054881648549888)

### Zollman Zoo

Meet the animals who call Zollman Zoo home during your travels in Byron. Amble around the area's parks or experience its art scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=920055270183727104)

## Top Byron Hotel Reviews

![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg)

### Hampton Inn Rochester-South

10/10 Excellent

"Very friendly staff always willing to help. Great breakfast area with evening soup which was wonderful on these cold January nights. Housekeeping did not come one time during our stay and the front desk was accommodating to give us extra towels and supplies we needed for our room."

[](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information)

![Staybridge Suites Rochester - Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/60000000/59810000/59802900/59802871/2feb2cc1_y.jpg)

### Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Spotless, impeccable lobby, very kind staff, spacious room, clean pool and decent breakfast options. "

[](https://expedia.ca/Rochester-Hotels-Staybridge-Suites-Rochester-St-Marys-Area.h59802871.Hotel-Information)

![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg)

### Kahler Grand Hotel

10/10 Excellent

"Overall hospitality "

[](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information)

![Holiday Inn Express Rochester South - Mayo Area by IHG](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/62a372dd_y.jpg)

### Holiday Inn Express Rochester South - Mayo Area by IHG

10/10 Excellent

"Staff was very friendly, facilities were clean, nice breakfast area, pool area was clean. Room was very nice and large. We had no issues and will stay again at our next Mayo visit! "

[](https://expedia.ca/Rochester-Hotels-Comfort-Suites.h2184971.Hotel-Information)

![Hotel Indigo Rochester – Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg)

### Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"Nice staff. The room is shaped a bit weird and cramped but it was clean and cozy. "

[](https://expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information)

![Home2 Suites by Hilton Rochester Mayo Clinic Area](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/444e106b_y.jpg)

### Home2 Suites by Hilton Rochester Mayo Clinic Area

10/10 Excellent

"clean "

[](https://expedia.ca/Rochester-Hotels-Home2-Suites-By-Hilton-Rochester-Mayo-Clinic-Area.h23512633.Hotel-Information)

![AmericInn by Wyndham Rochester Near Mayo Clinic](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg)

### AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent

"The room was beautiful and spacious for my family and I. The staff I encountered was very friendly and helpful but a specific gentleman was especially helpful with every greeting, he had a smile and was extremely informational even with my kods Playstation! 5 stars and i would definitely stay here again as well as recommend others to stay here. 😃 ❤️ 💙 "

[](https://expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information)

![Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/b33056f7_y.jpg)

### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent

"The hotel was clean. I still do not like your small pillows, but the rest of the bedding were super comfortable. The staff were friendly and helpful. "

[](https://expedia.ca/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg)

### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

10/10 Excellent

"It was nice and clean. The halls was quiet "

[](https://expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information)

## More cheap stays in Byron

![Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/1b6617d7_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

4210 Highway 52 North Rochester MN

CA $84

CA $96 total

Feb 12 - Feb 13

includes taxes & fees

7.8/10 Good! (1,000 reviews)

[](https://expedia.ca/Rochester-Hotels-Microtel-Inn-Suites-By-Wyndham-Rochester-North-Mayo-Clinic.h116574.Hotel-Information)

![Econo Lodge Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Econo Lodge Mayo Clinic Area

1850 S Broadway Rochester MN

CA $86

CA $99 total

Feb 21 - Feb 22

includes taxes & fees

9/10 Wonderful! (929 reviews)

[](https://expedia.ca/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information)

![Med City Inn & Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/821fc05d_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

CA $103

CA $118 total

Feb 23 - Feb 24

includes taxes & fees

7.8/10 Good! (1,002 reviews)

[](https://expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information)

![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn Rochester-South

1755 S Broadway Rochester MN

CA $109

CA $126 total

Mar 7 - Mar 8

includes taxes & fees

9/10 Wonderful! (1,003 reviews)

[](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information)

![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

1517 16th St Sw Rochester MN

CA $129

CA $148 total

Feb 10 - Feb 11

includes taxes & fees

8.2/10 Very Good! (811 reviews)

[](https://expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information)

![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN

CA $148

CA $170 total

Feb 12 - Feb 13

includes taxes & fees

8.8/10 Excellent! (1,003 reviews)

[](https://expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information)

## Hotels in Byron with star rating

![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg)

4 Star Hotels

2 properties

[](https://expedia.ca/4Star-Byron-Hotels.s40-0-d553248623858895563.Travel-Guide-Filter-Hotels)

![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg)

3 Star Hotels

42 properties

[](https://expedia.ca/3Star-Byron-Hotels.s30-0-d553248623858895563.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg)

2 Star Hotels

52 properties

[](https://expedia.ca/2Star-Byron-Hotels.s20-0-d553248623858895563.Travel-Guide-Filter-Hotels)

## Frequently asked questions

### What is the best area to stay in Byron?

> This area is the commercial hub of Byron. It's characterised by modern developments and easy access to major roads, making it simple to navigate. You'll find a selection of dining options and local services here, all designed for convenience.
> 
>   
> For business travellers, staying in this area is ideal due to its proximity to local businesses and the main arterial routes. The hotels here often cater to this audience with facilities like meeting rooms and high-speed internet, ensuring a productive stay.
> 
>   
> Families visiting Byron will also find this area practical. The accessibility to US-14 means less time travelling and more time enjoying local activities or exploring nearby Rochester.

### When is the best time to go to Byron?

> May and June offer mild temperatures, generally ranging from 10°C to 25°C, making it pleasant for exploring the local parks and trails. The greenery is lush, and it's a good time for those who enjoy hiking or cycling without the peak summer heat.
> 
>   
> July and August are the warmest months, with average temperatures usually between 20°C and 30°C. This is ideal for enjoying the nearby lakes and rivers, such as those found in Whitewater State Park, which is a short drive away. Families often find these months great for a holiday due to the warm weather and school breaks.
> 
>   
> September and October bring cooler temperatures, typically between 5°C and 20°C, and the stunning autumn foliage. This period is excellent for scenic drives and enjoying the vibrant colours of the changing leaves. It's a wonderful time for couples seeking a peaceful getaway and picturesque views.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Byron hotel booking with Expedia?

### How much is the nightly rate at a Byron hotel?

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- [Wanamingo Hotels ](https://www.expedia.ca/Wanamingo-Hotels.d3000349019.Travel-Guide-Hotels)
- [Boutique Hotels in Washington ](https://www.expedia.ca/Washington-Rochester-Hotels-Boutique-Hotel.0-n900102744399208448-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels)
- [Zumbrota Hotels ](https://www.expedia.ca/Zumbrota-Hotels.d181483.Travel-Guide-Hotels)

- [Flights to Rochester ](https://www.expedia.ca/Cheap-Flights-To-Rochester.d3041.Travel-Guide-Flights)
- [Flights from Anchorage to Southeast Minnesota ](https://www.expedia.ca/lp/flights/178230/6233996/anchorage-to-southeast-minnesota)
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- [Flights from Tampa to Southeast Minnesota ](https://www.expedia.ca/lp/flights/602996/6233996/tampa-to-southeast-minnesota)

- [Visit Kasson ](https://www.expedia.ca/Kasson.dx6035256)
- [Visit Kutzky Park ](https://www.expedia.ca/Rochester-Kutzky-Park.dx553248635976473564)
- [Visit Northwest ](https://www.expedia.ca/Rochester-Northwest.dx900102874825277440)
- [Visit Washington ](https://www.expedia.ca/Rochester-Washington.dx900102744399208448)
- [Rochester Vacations ](https://www.expedia.ca/Rochester.d3041.Destination-Travel-Guides)
- [Visit Southeast Minnesota ](https://www.expedia.ca/Southeast-Minnesota.dx6233996)

- [Car rentals near Mayo Clinic ](https://www.expedia.ca/Car-Rentals-In-Mayo-Clinic.d6126906.Car-Rental-Guide)
- [Car rental Rochester ](https://www.expedia.ca/Car-Rentals-In-Rochester.d3041.Car-Rental-Guide)
- [Discount Quebec Rental Cars in Southeast Minnesota ](https://www.expedia.ca/Discount-Quebec-Car-Rentals-In-Southeast-Minnesota.d6233996-c1137.Car-Rental-Guide-Suppliers)

- [Rochester Vacation Rentals ](https://www.expedia.ca/Rochester-Vacation-Rentals.d3041.Travel-Guide-VacationRentals)

- [Book Hotels in Byron on Expedia.com ](https://www.expedia.com/Byron-Hotels.d553248623858895563.Travel-Guide-Hotels)

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