Title: Best Hotels Near Buffalo Museum of Science, Buffalo from CA $179 | Expedia.ca

  

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# Find hotels near Buffalo Museum of Science, Buffalo from CA $179

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## Check prices for these dates

Tonight

[Sep 16 - Sep 17](https://www.expedia.ca/Hotel-Search?regionId=6064413&startDate=2025-09-16&endDate=2025-09-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

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This weekend

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Next weekend

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## Top Hotels Close to Buffalo Museum of Science

## Our top choices for Buffalo Museum of Science hotels

![Interior](https://images.trvl-media.com/lodging/22000000/21860000/21856100/21856017/38125165.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/22000000/21860000/21856100/21856017/b1124684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Library](https://images.trvl-media.com/lodging/22000000/21860000/21856100/21856017/0af12965.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/22000000/21860000/21856100/21856017/30af5f06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### InnBuffalo off Elmwood

Elmwood Village, 3 km from Buffalo Museum of Science

10/10

Exceptional

(184)

"Beautitul place, a must stay"

CA $256

CA $286 total

includes taxes & fees

Oct 15 - Oct 16

[](https://www.expedia.ca/Buffalo-Hotels-InnBuffalo-Off-Elmwood.h21856017.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/91000000/90770000/90762900/90762810/33860f43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/91000000/90770000/90762900/90762810/7bda029a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sparrow Suite](https://images.trvl-media.com/lodging/91000000/90770000/90762900/90762810/24a2ac37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Robin Room](https://images.trvl-media.com/lodging/91000000/90770000/90762900/90762810/7f5680a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Buffalo Harmony House

Allentown, 3.2 km from Buffalo Museum of Science

10/10

Exceptional

(46)

"A great, unique spot with really great personal service. Amazing breakfast "

CA $329

CA $375 total

includes taxes & fees

Oct 6 - Oct 7

[](https://www.expedia.ca/Buffalo-Hotels-Buffalo-Harmony-House.h90762810.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/160000/159000/158959/2e0799e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/160000/159000/158959/fc686d9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/160000/159000/158959/dfd9177e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/1000000/160000/159000/158959/80e2350d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wyndham Garden Buffalo Downtown

Fruit Belt, 2 km from Buffalo Museum of Science

9.0/10

Wonderful

(1621)

"Enjoyed my stay very much!"

CA $193

CA $220 total

includes taxes & fees

Sep 29 - Sep 30

[](https://www.expedia.ca/Buffalo-Hotels-Wyndham-Garden-Buffalo-Downtown.h158959.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/1225a495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/28123e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Queen Bed (Suite)](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/174cf473.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Suite, 1 Queen Bed (Premium Room (Fireplace Grand Queen))](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/37ec72a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Mansion On Delaware Ave

Allentown, 3 km from Buffalo Museum of Science

9.4/10

Exceptional

(1014)

"Great, friendly, helpful staff Beautiful bathroom great bar and breakfast"

CA $263

CA $294 total

includes taxes & fees

Oct 15 - Oct 16

[](https://www.expedia.ca/Buffalo-Hotels-The-Mansion-On-Delaware-Ave.h692610.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/116000000/115340000/115334800/115334773/debc1f3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/116000000/115340000/115334800/115334773/c8096ad2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Mini-fridge](https://images.trvl-media.com/lodging/116000000/115340000/115334800/115334773/ec4765b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Studio Suite](https://images.trvl-media.com/lodging/116000000/115340000/115334800/115334773/03805232.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Buffalo Guesthouse

Allentown, 2.4 km from Buffalo Museum of Science

9.0/10

Wonderful

(69)

"Great place to stay"

CA $183

CA $205 total

includes taxes & fees

Oct 17 - Oct 18

[](https://www.expedia.ca/Buffalo-Hotels-Buffalo-Guesthouse.h115334773.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/9400/9305/84f1900d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9400/9305/4a8161fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/10000/9400/9305/29b4201d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/9400/9305/a9b12161.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Residence Inn by Marriott Buffalo Downtown

Allentown, 2.6 km from Buffalo Museum of Science

9.0/10

Wonderful

(328)

"One of the best hotel👌"

CA $414

CA $471 total

includes taxes & fees

Oct 1 - Oct 2

[](https://www.expedia.ca/Buffalo-Hotels-Residence-Inn-By-Marriott-Buffalo-Downtown.h9305.Hotel-Information)

![2 bars/lounges](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/1b8dbb7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/bde93c89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/ae3eb39b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hot springs](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/65405b68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Curtiss Hotel, an Ascend Collection Hotel

Downtown Buffalo, 3.4 km from Buffalo Museum of Science

9.2/10

Wonderful

(1007)

"It was a very nice stay."

CA $273

CA $310 total

includes taxes & fees

Sep 30 - Oct 1

[](https://www.expedia.ca/Buffalo-Hotels-Curtiss-Hotel.h17038248.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/14000000/13460000/13451300/13451237/6f487a3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![American cuisine](https://images.trvl-media.com/lodging/14000000/13460000/13451300/13451237/5fceb770.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/14000000/13460000/13451300/13451237/1993a3aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Traditional Room, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/14000000/13460000/13451300/13451237/08b053af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Westin Buffalo

Downtown Buffalo, 3.3 km from Buffalo Museum of Science

9.2/10

Wonderful

(397)

"My favorite place to stay in Buffalo. "

CA $395

CA $450 total

includes taxes & fees

Sep 21 - Sep 22

[](https://www.expedia.ca/Buffalo-Hotels-The-Westin-Buffalo.h13451237.Hotel-Information)

![Suite, 1 King Bed, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/7000000/6790000/6785900/6785857/ed7545be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/7000000/6790000/6785900/6785857/9d77ced9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/7000000/6790000/6785900/6785857/ff355930.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/7000000/6790000/6785900/6785857/2d06ae33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western on the Avenue

Allentown, 2.8 km from Buffalo Museum of Science

8.6/10

Excellent

(1005)

"Excellent customer service Great breakfast "

CA $210

CA $251 total

includes taxes & fees

Sep 23 - Sep 24

[](https://www.expedia.ca/Buffalo-Hotels-Best-Western-On-The-Avenue.h6785857.Hotel-Information)

![1 bedroom, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/73c0de62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/a56cf142.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business centre](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/00c812b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/ee391dcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

3.1 km from Buffalo Museum of Science

8.6/10

Excellent

(1003)

"Perfect for what we were there for. "

CA $179

CA $204 total

includes taxes & fees

Oct 1 - Oct 2

[](https://www.expedia.ca/Buffalo-Hotels-Holiday-Inn-Express-Suites-Buffalo-Downtown-Medical-CTR.h6258.Hotel-Information)

![In-room safe, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/32000000/31870000/31863400/31863371/a607358b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/32000000/31870000/31863400/31863371/6210ae8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, lunch, dinner served; Italian cuisine](https://images.trvl-media.com/lodging/32000000/31870000/31863400/31863371/081f6ee5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/32000000/31870000/31863400/31863371/58a14332.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aloft Buffalo Downtown

Downtown Buffalo, 3 km from Buffalo Museum of Science

8.2/10

Very good

(341)

"Great place to stay, but there is a club on top of the hotel. Hotel does give you ear plugs. Great scenery as well. "

CA $274

CA $312 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/Buffalo-Hotels-Aloft-Buffalo-Downtown.h31863371.Hotel-Information)

![Luxury House, 4 Bedrooms, Patio, City View | Private kitchen](https://images.trvl-media.com/lodging/111000000/110140000/110138900/110138870/e698becb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/111000000/110140000/110138900/110138870/efe76f18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Casino](https://images.trvl-media.com/lodging/111000000/110140000/110138900/110138870/41b79a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/111000000/110140000/110138900/110138870/w1918h1912x0y2-37cf1eb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Summer Street Guest House

Bryant, 3 km from Buffalo Museum of Science

10/10

Exceptional

(2)

"Beautiful old mansion lovingly restored with so much charm! This was a fantastic location for our needs. We were able to walk past estates and cute cottages with beautiful gardens to shops and restaurants for breakfast and lunch. Close to the Buffalo History Museum and other local attractions and about 20 minutes from Niagara Falls. Our host was able to let us have an early check in time and he gave us a tour of the house with some interesting background info. He lives quietly on the third...

CA $495

CA $707 total

includes taxes & fees

Sep 22 - Sep 23

[](https://www.expedia.ca/Buffalo-Hotels-Summer-Street-Guest-House.h110138870.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/10000000/9790000/9787900/9787810/610165f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9790000/9787900/9787810/b5e57f39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/10000000/9790000/9787900/9787810/94720655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, in-room safe, laptop workspace](https://images.trvl-media.com/lodging/10000000/9790000/9787900/9787810/bc225fe6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Buffalo Marriott at LECOM HARBORCENTER

Downtown Buffalo, 4.4 km from Buffalo Museum of Science

9.4/10

Exceptional

(871)

"Good restaurant on the property!"

CA $358

CA $408 total

includes taxes & fees

Oct 2 - Oct 3

[](https://www.expedia.ca/Buffalo-Hotels-Buffalo-Marriott-At-LECOM-HARBORCENTER.h9787810.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/900000/892600/892571/3b4ec85c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 Bedroom | Private kitchen](https://images.trvl-media.com/lodging/1000000/900000/892600/892571/e8fe22a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/900000/892600/892571/33e451a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/900000/892600/892571/a6db64ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Buffalo Downtown

Downtown Buffalo, 3.4 km from Buffalo Museum of Science

8.8/10

Excellent

(1003)

"Enjoyed our stay"

CA $242

CA $276 total

includes taxes & fees

Oct 1 - Oct 2

[](https://www.expedia.ca/Buffalo-Hotels-Hampton-Inn-Suites-Buffalo-Downtown.h892571.Hotel-Information)

![Hallway](https://images.trvl-media.com/lodging/19000000/18140000/18136300/18136290/16863301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/19000000/18140000/18136300/18136290/9874aa4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/19000000/18140000/18136300/18136290/7ee1a124.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/19000000/18140000/18136300/18136290/47e282c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Richardson Hotel

Elmwood Bidwell, 4.1 km from Buffalo Museum of Science

9.0/10

Wonderful

(1006)

"Had an amazing stay at the Richardson. Such a beautiful property. Very comfortable room. Staff members were incredibly nice. Would definitely recommend. "

CA $210

CA $238 total

includes taxes & fees

Sep 17 - Sep 18

[](https://www.expedia.ca/Buffalo-Hotels-Hotel-Henry-Urban-Resort.h18136290.Hotel-Information)

![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/9000000/8750000/8745500/8745457/4777f940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/9000000/8750000/8745500/8745457/4b4f30a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/9000000/8750000/8745500/8745457/0ce91b56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/9000000/8750000/8745500/8745457/20f6c548.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Garden Inn Buffalo Downtown

Downtown Buffalo, 3.5 km from Buffalo Museum of Science

8.6/10

Excellent

(1002)

"Super friendly staff, very spacious and clean!"

CA $210

CA $243 total

includes taxes & fees

Oct 6 - Oct 7

[](https://www.expedia.ca/Buffalo-Hotels-Hilton-Garden-Inn-Buffalo-Downtown.h8745457.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/8000000/7910000/7901100/7901087/40ce07c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/8000000/7910000/7901100/7901087/846e9796.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/8000000/7910000/7901100/7901087/865c992e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/8000000/7910000/7901100/7901087/59c0d1fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard Buffalo Downtown / Canalside

Downtown Buffalo, 4.3 km from Buffalo Museum of Science

9.0/10

Wonderful

(928)

"Beautiful property "

CA $286

CA $325 total

includes taxes & fees

Oct 6 - Oct 7

[](https://www.expedia.ca/Buffalo-Hotels-Courtyard-Buffalo-Downtown-Canalside.h7901087.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/6000000/5060000/5058700/5058670/ce7e42e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Studio, 1 Queen Bed, Non Smoking | Private kitchen](https://images.trvl-media.com/lodging/6000000/5060000/5058700/5058670/4690f91d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/6000000/5060000/5058700/5058670/6aa8ebc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/6000000/5060000/5058700/5058670/639565a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel at the Lafayette Trademark Collection by Wyndham

Downtown Buffalo, 3.6 km from Buffalo Museum of Science

8.6/10

Excellent

(1002)

"The room was immaculately clean and the towels and bedding were top notch. However…the hotel itself is just "

CA $207

CA $235 total

includes taxes & fees

Oct 6 - Oct 7

[](https://www.expedia.ca/Buffalo-Hotels-Hotel-At-The-Lafayette-Trademark-Collection-By-Wyndham.h5058670.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/3000000/2610000/2607100/2607052/31769e9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/3000000/2610000/2607100/2607052/5f9a4027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite, 1 King Bed with Sofa bed, Corner](https://images.trvl-media.com/lodging/3000000/2610000/2607100/2607052/7fced7e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2610000/2607100/2607052/1a25d3b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Embassy Suites Buffalo

Downtown Buffalo, 3.4 km from Buffalo Museum of Science

8.2/10

Very good

(1000)

"It was a very nice stay."

CA $245

CA $278 total

includes taxes & fees

Oct 6 - Oct 7

[](https://www.expedia.ca/Buffalo-Hotels-Embassy-Suites-Buffalo.h2607052.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/23200/23101/00561234.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/30000/23200/23101/fe2b6be7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23200/23101/f2d28773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/23200/23101/790a170b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency Buffalo / Hotel and Conference Center

Downtown Buffalo, 3.4 km from Buffalo Museum of Science

8.0/10

Very good

(1560)

"nice place to stay"

CA $199

CA $233 total

includes taxes & fees

Sep 30 - Oct 1

[](https://www.expedia.ca/Buffalo-Hotels-Hyatt-Regency-Buffalo-Hotel-And-Conference-Center.h23101.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-09-30&endDate=2025-10-01&regionId=6064413&adults=2&sort=RECOMMENDED&openPlayBack=true)

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Save an average of 15% on thousands of hotels when you're signed in

[Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FBuffalo-Museum-Of-Science-Hotels.0-l6064413-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FBuffalo-Museum-Of-Science-Hotels.0-l6064413-0.Travel-Guide-Filter-Hotels)

## Top Buffalo Museum of Science Hotel Reviews

![The Mansion On Delaware Ave](//images.trvl-media.com/lodging/1000000/700000/692700/692610/1225a495_y.jpg)

### The Mansion On Delaware Ave

10/10 Excellent

"Great stay. Nice place. Cool neighborhood"

[](https://expedia.ca/Buffalo-Hotels-The-Mansion-On-Delaware-Ave.h692610.Hotel-Information)

![Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG](//images.trvl-media.com/lodging/1000000/10000/6300/6258/73c0de62_y.jpg)

### Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

10/10 Excellent

"Clean, large room. Nice bed "

[](https://expedia.ca/Buffalo-Hotels-Holiday-Inn-Express-Suites-Buffalo-Downtown-Medical-CTR.h6258.Hotel-Information)

![Buffalo Guesthouse](//images.trvl-media.com/lodging/116000000/115340000/115334800/115334773/debc1f3c_y.jpg)

### Buffalo Guesthouse

10/10 Excellent

"We loved our stay! So cozy, and the staff couldn’t have been more accommodating. So clean and lovely. That bed was one of the most comfortable anywhere I’ve stayed. Walkable to cool restaurants and bars. The beautiful young lady at the front desk even helped with our bags. Unfortunately I left my medicine and the man made sure those meds were sent to our next stop! I would never stay anywhere else in Buffalo. "

[](https://expedia.ca/Buffalo-Hotels-Buffalo-Guesthouse.h115334773.Hotel-Information)

![Hyatt Regency Buffalo / Hotel and Conference Center](//images.trvl-media.com/lodging/1000000/30000/23200/23101/00561234_y.jpg)

### Hyatt Regency Buffalo / Hotel and Conference Center

10/10 Excellent

"Last minute decision before going to Niagara. Were able to check in right away! "

[](https://expedia.ca/Buffalo-Hotels-Hyatt-Regency-Buffalo-Hotel-And-Conference-Center.h23101.Hotel-Information)

![Wyndham Garden Buffalo Downtown](//images.trvl-media.com/lodging/1000000/160000/159000/158959/2e0799e1_y.jpg)

### Wyndham Garden Buffalo Downtown

10/10 Excellent

"Great experience!! Everything was super clean and great customer service!!"

[](https://expedia.ca/Buffalo-Hotels-Wyndham-Garden-Buffalo-Downtown.h158959.Hotel-Information)

![Residence Inn by Marriott Buffalo Downtown](//images.trvl-media.com/lodging/1000000/10000/9400/9305/84f1900d_y.jpg)

### Residence Inn by Marriott Buffalo Downtown

10/10 Excellent

"We always stay at the residence inn when visiting Buffalo. It is an extremely spacious room with a full refrigerator and lots of space to relax outside of the bed area. The staff are always friendly and helpful and the free self parking is s great asset. The room cost is also very competitive based on the room amenities. We will continue to stay at the residence inn any time we are in Buffalo. "

[](https://expedia.ca/Buffalo-Hotels-Residence-Inn-By-Marriott-Buffalo-Downtown.h9305.Hotel-Information)

![Beautiful Victorian House](//images.trvl-media.com/lodging/100000000/99560000/99553600/99553586/w543h683x241y0-eba01daa_y.jpg)

### Beautiful Victorian House

10/10 Excellent

"well kept spacious house with a nice outdoor space."

[](https://expedia.ca/Buffalo-Hotels-Beautiful-Victorian-House.h99553586.Hotel-Information)

![ Elmwood Village home](//images.trvl-media.com/lodging/117000000/116720000/116718300/116718232/4dff850c_edited_6dd8_y.jpg)

### Elmwood Village home

10/10 Excellent

"Check-in to this lovely home was easy, and we quickly settled in for our stay. The kitchen was very well equipped with everything we needed to fix our meals. We especially enjoyed the sun room at the front. Thank you Mary. "

[](https://expedia.ca/Buffalo-Hotels-Cozy-Home-In-Elmwood-Village.h116718232.Hotel-Information)

![Beautiful house](//images.trvl-media.com/lodging/105000000/104330000/104321200/104321127/17597da8_y.jpg)

### Beautiful house

10/10 Excellent

"The house was a nice size and checking in was seamless "

[](https://expedia.ca/Buffalo-Hotels-Beautiful-House.h104321127.Hotel-Information)

### Hotels near Other Buffalo Attractions

[](https://expedia.ca/Canisius-College-Hotels.0-l6181324-0.Travel-Guide-Filter-Hotels)

![Canisius College](https://mediaim.expedia.com/destination/2/fa0f166e5a5e0ebec8bb0cd2701f1416.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Canisius College

3/5(1 review)

Explore the campus of Canisius College, during your trip to Buffalo. Experience the area's great live music and entertainment choices.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6181324)

[](https://expedia.ca/Buffalo-Central-Terminal-Hotels.0-l6064429-0.Travel-Guide-Filter-Hotels)

![Buffalo Central Terminal](https://mediaim.expedia.com/destination/2/72e6c8b72402c242a3cc1ba205e61f08.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Buffalo Central Terminal

You can find out about the history of Buffalo when you stop by Buffalo Central Terminal. Experience the entertainment choices and great live music in this vibrant area.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6064429)

[](https://expedia.ca/Forest-Lawn-Cemetery-Hotels.0-l6064407-0.Travel-Guide-Filter-Hotels)

![Forest Lawn Cemetery which includes a lake or waterhole](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/82000/82180-Forest-Lawn-Cemetery.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Forest Lawn Cemetery

Take a tour through Buffalo’s bucolic and art-filled cemetery, which is home to a U.S. president’s gravesite and a mausoleum designed by Frank Lloyd Wright.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6064407)

[](https://expedia.ca/War-Memorial-Stadium-Hotels.0-l553248621558038887-0.Travel-Guide-Filter-Hotels)

#### War Memorial Stadium

Explore the great outdoors at War Memorial Stadium, a lovely green space in Buffalo. Experience the area's acclaimed theater scene and great live music.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621558038887)

[](https://expedia.ca/Paul-Robeson-Theater-Hotels.0-l6064431-0.Travel-Guide-Filter-Hotels)

#### Paul Robeson Theater

Enjoy a show at Paul Robeson Theater, a theater with a story to tell in Buffalo. Experience the area's great live music and acclaimed theater scene.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6064431)

[](https://expedia.ca/African-American-Cultural-Center-Hotels.0-l6064445-0.Travel-Guide-Filter-Hotels)

#### African American Cultural Center

African American Cultural Center is just one of the places to see in Buffalo, so why not enjoy the other things to explore during your travels? Experience the area's acclaimed theater scene and entertainment choices.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6064445)

## Frequently asked questions

### What's the area like around Buffalo Museum of Science?

> Buffalo Museum of Science is located in a historic area of Buffalo known for its great live music scene. If you're looking for a convenient place to stay, check out the 13 hotels and other accommodations you'll find within a mile.

### What's the best hotel to stay near Buffalo Museum of Science?

> [Hyatt Regency Buffalo / Hotel and Conference Center](https://www.expedia.ca/Buffalo-Hotels-Hyatt-Regency-Buffalo-Hotel-And-Conference-Center.h23101.Hotel-Information) is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an indoor pool. It's located 2.1 mi (3.4 km) from Buffalo Museum of Science. Other good choices within 5 miles include [Wyndham Garden Buffalo Downtown](https://www.expedia.ca/Buffalo-Hotels-Wyndham-Garden-Buffalo-Downtown.h158959.Hotel-Information) and [Buffalo Guesthouse](https://www.expedia.ca/Buffalo-Hotels-Buffalo-Guesthouse.h115334773.Hotel-Information).

### How many hotels will I be able to find close to Buffalo Museum of Science?

> Expedia has 13 hotels and other accommodations within a mile from Buffalo Museum of Science.

### If I need to cancel the hotel reservation for my stay near Buffalo Museum of Science, will I receive a refund?

> Yes, most hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the top deals on offer near Buffalo Museum of Science.

### Where can I learn more about changing or cancelling my trip in the area near Buffalo Museum of Science?

> For more information about picking new dates or cancelling your stay near Buffalo Museum of Science, go to [https://www.expedia.com/service/](https://www.expedia.com/service/).

### What can I see and do near Buffalo Museum of Science?

> Study the collections at Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site, Buffalo AKG Art Museum, or Buffalo History Museum. Some landmarks that you won't want to miss include Buffalo Central Terminal, Michigan Street Baptist Church, and Statler Tower. You can watch performances at Shea's Performing Arts Center, Kleinhans Music Hall, and Road Less Traveled Productions if you're interested in local theater.

## Explore a world of travel with Expedia

-   Explore a world of travel with Expedia

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Hotels

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Packages

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