Title: Book the Best Vatican LUXURY Hotels - Upscale Hotels in Vatican, Rome | Expedia.ca [Vatican Travel Guide](https://expedia.ca/Rome-Vatican.dx6046253)[Vacation Rentals in Rome](https://expedia.ca/Rome-Vacation-Rentals.d179899.Travel-Guide-VacationRentals)[Flights to Rome](https://expedia.ca/Cheap-Flights-To-Rome.d179899.Travel-Guide-Flights)[Things to do in Rome](https://expedia.ca/Things-To-Do-In-Rome.d179899.Travel-Guide-Activities)[Vatican Car Rentals](https://expedia.ca/Car-Rentals-In-Vatican.d6046253.Car-Rental-Guide)[Vatican Vacations](https://expedia.ca/Vatican.d6046253.Destination-Travel-Guides) ![Rome, Vatican city; Shutterstock ID 364719503](https://images.trvl-media.com/place/6046253/267902cf-6b70-47a3-a839-10db3dc044c9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6046253/267902cf-6b70-47a3-a839-10db3dc044c9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Vatican Luxury Hotels Tonight [Jan 15 - Jan 16](https://www.expedia.ca/Hotel-Search?regionId=6046253&startDate=2026-01-15&endDate=2026-01-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Jan 16 - Jan 17](https://www.expedia.ca/Hotel-Search?regionId=6046253&startDate=2026-01-16&endDate=2026-01-17&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6046253&startDate=2026-01-16&endDate=2026-01-18&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6046253&startDate=2026-01-23&endDate=2026-01-25&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Vatican luxury hotels ![Breakfast area](https://images.trvl-media.com/lodging/6000000/5210000/5208900/5208849/7c177e3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Double Room Single Use, 1 Double Bed, City View | Bathroom](https://images.trvl-media.com/lodging/6000000/5210000/5208900/5208849/c829969c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, memory foam beds, minibar](https://images.trvl-media.com/lodging/6000000/5210000/5208900/5208849/aebfa89b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/6000000/5210000/5208900/5208849/9ab2dc58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lunaria Suites Rome [](https://www.expedia.ca/Rome-Hotels-Lunaria-Suites-Rome-Luxury-In-St-Peter.h5208849.Hotel-Information) Rome City Centre 9.4/10 Exceptional (118 reviews) "Ok" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $344 CA $398 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Rome-Hotels-Lunaria-Suites-Rome-Luxury-In-St-Peter.h5208849.Hotel-Information) ![Superior Double Room, City View](https://images.trvl-media.com/lodging/6000000/5620000/5614600/5614534/e2d69bb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/6000000/5620000/5614600/5614534/0c24bbb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/6000000/5620000/5614600/5614534/e6f96b06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/6000000/5620000/5614600/5614534/66284709.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury on the River [](https://www.expedia.ca/Rome-Hotels-Luxury-On-The-River.h5614534.Hotel-Information) Rome City Centre 9.2/10 Wonderful (860 reviews) "Great location !!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria Fernanda CA $118 CA $149 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Rome-Hotels-Luxury-On-The-River.h5614534.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/20000/19800/19746/6e4a1ae2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/19800/19746/de48c3af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/19800/19746/c342b832.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/20000/19800/19746/2ca5598b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Giulio Cesare [](https://www.expedia.ca/Rome-Hotels-Hotel-Giulio-Cesare.h19746.Hotel-Information) Rome City Centre 8.6/10 Excellent (1,000 reviews) "staff were helpful, room facilities were good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) PHILLIP [](https://www.expedia.ca/Rome-Hotels-Hotel-Giulio-Cesare.h19746.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/860000/856900/856829/abfd2e6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room](https://images.trvl-media.com/lodging/1000000/860000/856900/856829/379415d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856900/856829/6432bb9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/860000/856900/856829/60cb2e91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Isa [](https://www.expedia.ca/Rome-Hotels-Hotel-Isa.h856829.Hotel-Information) Rome City Centre 9.4/10 Exceptional (1,011 reviews) "We loved our 3-night stay at Hotel Isa. The location made everything convenient. The staff was helpful and friendly and breakfast was always wonderful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen CA $238 CA $286 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Rome-Hotels-Hotel-Isa.h856829.Hotel-Information) ![Honeymoon Suite](https://images.trvl-media.com/lodging/3000000/2540000/2531900/2531847/12d009a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Suite](https://images.trvl-media.com/lodging/3000000/2540000/2531900/2531847/504310bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Suite](https://images.trvl-media.com/lodging/3000000/2540000/2531900/2531847/ce75924f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2540000/2531900/2531847/e0ade841.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MDM Guesthouse [](https://www.expedia.ca/Rome-Hotels-MDM-Guesthouse.h2531847.Hotel-Information) Rome City Centre 8.2/10 Very good (597 reviews) "Clean room and great staff. Highly recommend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roy [](https://www.expedia.ca/Rome-Hotels-MDM-Guesthouse.h2531847.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/80000/72900/72827/d2047bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/80000/72900/72827/c94c67f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/80000/72900/72827/660e5932.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/80000/72900/72827/61cd2cbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Olympic [](https://www.expedia.ca/Rome-Hotels-Grand-Hotel-Olympic.h72827.Hotel-Information) Rome City Centre 7.6/10 Good (1,085 reviews) "Good place near Vatican. Room was good. Great breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vikrant CA $224 CA $270 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Rome-Hotels-Grand-Hotel-Olympic.h72827.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1610000/1600500/1600405/18d6dce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms (Noble floor)](https://images.trvl-media.com/lodging/2000000/1610000/1600500/1600405/34bee540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1610000/1600500/1600405/d2879fd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite](https://images.trvl-media.com/lodging/2000000/1610000/1600500/1600405/eed367f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Laetitia [](https://www.expedia.ca/Rome-Hotels-Villa-Laetitia.h1600405.Hotel-Information) Municipio I 9.2/10 Wonderful (374 reviews) "Great hotel Clean room Great breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $316 CA $367 total includes taxes & fees Jan 24 - Jan 25 [](https://www.expedia.ca/Rome-Hotels-Villa-Laetitia.h1600405.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1340000/1339900/1339894/fca175ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Car charging station](https://images.trvl-media.com/lodging/2000000/1340000/1339900/1339894/557659a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1340000/1339900/1339894/aef86e69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1340000/1339900/1339894/59e9883e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vatican Suites Hotel & Residence [](https://www.expedia.ca/Rome-Hotels-Vatican-Suites-Hotel-Residence.h1339894.Hotel-Information) Vatican 7.6/10 Good (736 reviews) "Toplage, dabei ruhig ; super Preis-Leistungsverhältnis;" ![Germany](https://a.travel-assets.com/egds/marks/flags/de.svg) Anonymous traveller [](https://www.expedia.ca/Rome-Hotels-Vatican-Suites-Hotel-Residence.h1339894.Hotel-Information) ![Suite | View from room](https://images.trvl-media.com/lodging/12000000/11750000/11743100/11743083/08da23a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11750000/11743100/11743083/80451e68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/12000000/11750000/11743100/11743083/72510a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, 1 Bedroom | Room amenity](https://images.trvl-media.com/lodging/12000000/11750000/11743100/11743083/4078a623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Elenoire Rooms & Suite [](https://www.expedia.ca/Rome-Hotels-Elenoire-Rooms-Suite.h11743083.Hotel-Information) Rome City Centre 9.2/10 Wonderful (97 reviews) "It was kept very clean. There was lovely free coffee and buiscuits every day. I could not get the tv to work as some nights we were exhausted with walking so wanted to just relax with a look at the news etc. I would definitely recommend as very near to all tourist attractions" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Pauline CA $279 CA $327 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Rome-Hotels-Elenoire-Rooms-Suite.h11743083.Hotel-Information) ![Signature Suite, 1 Bedroom](https://images.trvl-media.com/lodging/1000000/530000/526300/526245/80c27ad5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Triple Room](https://images.trvl-media.com/lodging/1000000/530000/526300/526245/0c5ed9e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, Italian cuisine](https://images.trvl-media.com/lodging/1000000/530000/526300/526245/dcd7d663.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Triple Room](https://images.trvl-media.com/lodging/1000000/530000/526300/526245/664f1adf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Le Méridien Visconti Rome [](https://www.expedia.ca/Rome-Hotels-Le-Meridien-Visconti-Rome.h526245.Hotel-Information) Rome City Centre 8.8/10 Excellent (1,000 reviews) "Great hotel, convenient location." ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Edgar CA $262 CA $313 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/Rome-Hotels-Le-Meridien-Visconti-Rome.h526245.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-29&endDate=2026-01-30®ionId=6046253&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Price trends for hotels in Vatican | Less expensive | More expensive | Next month | | -------------- | -------------- | ---------- | | January | September | CA $147 | | Month | Price | | --------- | ------- | | January | CA $123 | | February | CA $147 | | March | CA $180 | | April | CA $227 | | May | CA $243 | | June | CA $223 | | July | CA $213 | | August | CA $201 | | September | CA $244 | | October | CA $236 | | November | CA $185 | | December | CA $189 | Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Vatican. Select dates and complete search for nightly totals inclusive of taxes and fees. ## Find out more about Vatican ### Vaticanand its attractions for luxury travelers Nestled in the heart of Rome, the Vatican neighbourhood offers a unique blend of rich history and luxury, perfect for discerning travellers. Begin your exploration at St. Peter's Basilica, where the awe-inspiring architecture and magnificent artworks, including Michelangelo's Pietà, create a truly unforgettable experience. Just steps away, the Vatican Museums provide an exclusive opportunity to admire the masterpieces of the Renaissance, with private guided tours available for a more personalised visit. Don’t miss the serene beauty of the Vatican Gardens, where a private stroll reveals stunning landscapes and hidden gems away from the bustling crowds. After a day of exploration, indulge in exquisite dining at one of the local Michelin-starred restaurants, where innovative Italian cuisine awaits. Finally, unwind at one of the luxury hotels nearby, such as the Hotel de Russie, where lavish accommodations blend seamlessly with impeccable service, ensuring a stay that feels both exclusive and comfortable. With the convenience of your hotel just moments from these cultural landmarks, you can enjoy the best of Vatican City while being pampered in style. ### Find the best luxury hotels and resorts in Vatican For travellers seeking a luxurious experience in the heart of Vatican City, these hotels provide exceptional comfort, elegant amenities, and a refined atmosphere. [**Casa Mia Vaticano Guest House**](https://www.expedia.ca/Rome-Hotels-Casa-Mia-Vaticano.h13198352.Hotel-Information) - **Why it's great for a luxury retreat:** Casa Mia Vaticano Guest House provides a luxurious escape with a remarkable guest review rating of 9.8\. This elegant guest house features premium bedding and Frette Italian sheets, ensuring a lavish sleep experience. The attentive concierge service further enhances the luxury experience, making it an ideal choice for those seeking personalised attention during their stay. - **Other amenities:** Guests can enjoy a range of amenities including free airport shuttle services, a kitchenette in select rooms, and daily housekeeping. The hotel also offers a balcony for relaxation, along with environmentally friendly cups and free toiletries. Parking options nearby add to the convenience, making this guest house a top choice for luxury travellers. - **Neighborhood:** Vatican - **Nearby attractions:** St. Peter's Square - 1.6 km, Sistine Chapel - 1.7 km, St. Peter's Basilica - 1.5 km [**Leonardo Da Vinci Guest House**](https://www.expedia.ca/Rome-Hotels-Leonardo-Da-Vinci-Guest-House.h16328381.Hotel-Information) - **Why it's great for a luxury retreat:** With an impressive guest review rating of 9.8, Leonardo Da Vinci Guest House is perfect for those in search of luxury and comfort. The hotel features premium bedding and Egyptian cotton sheets, ensuring guests enjoy a restful night's sleep. Its elegant stay is complemented by attentive service, creating a truly indulgent experience in the heart of Vatican City. - **Other amenities:** This guest house provides a range of additional features including daily housekeeping, onsite parking, and convenient airport transportation. Guests can also take advantage of early check-in and late check-out options, enhancing their travel flexibility. The presence of a grocery store nearby, along with a carport and various parking options, makes this hotel particularly accommodating for luxury travellers. - **Neighborhood:** Vatican - **Nearby attractions:** St. Peter's Square - 1 km, Sistine Chapel - 1.1 km, St. Peter's Basilica - 0.9 km [**New Design St. Peter**](https://www.expedia.ca/Rome-Hotels-New-Design-St-Peter.h12625682.Hotel-Information) - **Why it's great for a luxury retreat:** New Design St. Peter is a luxurious retreat, offering travellers an impressive guest review rating of 9.4\. The hotel prides itself on its stylish interior, premium bedding, and onsite shopping that caters to travelers. With private hot tubs available, this hotel ensures a rejuvenating stay for those looking to unwind in elegance after a day exploring the Vatican. - **Other amenities:** Additional offerings include contactless check-in, airport shuttle services, and free cribs for families. The hotel also features a garden area, daily housekeeping, and complimentary toiletries for added convenience. Guests can enjoy the charm of a traditional hotel design while indulging in modern amenities that enhance their overall experience. - **Neighborhood:** Vatican - **Nearby attractions:** St. Peter's Square - 1.1 km, Castel Sant'Angelo - 1.5 km, Sistine Chapel - 1.5 km [**Mama Shelter Roma**](https://www.expedia.ca/Rome-Hotels-Mama-Shelter-Roma.h64593148.Hotel-Information) - **Why it's great for a luxury retreat:** Mama Shelter Roma stands out as a premier choice for luxury travellers, a remarkable guest review rating of 9.0\. With opulent amenities such as an indoor pool, a rejuvenating spa, and a rooftop terrace, this hotel creates an inviting sanctuary amidst the bustling city. Guests can indulge in the spa's daily services and unwind in the hot tub, making their stay a truly relaxing experience. - **Other amenities:** In addition to the luxurious features, Mama Shelter Roma offers a variety of conveniences including air conditioning, a fitness centre, and complimentary toiletries. Guests can enjoy daily housekeeping and the unique opportunity to explore historical sites nearby. The hotel also provides free rollaway beds, electric car charging stations, and a delightful garden space, ensuring a memorable stay for all visitors. - **Neighborhood:** Vatican - **Nearby attractions:** St. Peter's Square - 2.4 km, Castel Sant'Angelo - 2.3 km, Sistine Chapel - 2.3 km [**Hotel Metropolis**](https://www.expedia.ca/Rome-Hotels-Hotel-Metropolis.h3604052.Hotel-Information) - **Why it's great for a luxury retreat:** Hotel Metropolis is a luxurious accommodation with a solid guest review rating of 8.2, perfect for travellers seeking comfort and style. This hotel features suites for an extra touch of elegance, alongside premium bedding and a concierge service to cater to guests' every need. With a private hot tub available, visitors can indulge in a serene retreat after exploring the wonders of Vatican City. - **Other amenities:** Beyond luxury, the hotel provides a range of conveniences such as free cribs, airport transportation, and daily housekeeping. Guests can enjoy a romantic atmosphere, with options for airport shuttles available 24 hours a day. The hotel also features a snack bar and offers transfers and shuttles to enhance the overall experience, ensuring a delightful stay for all. - **Neighborhood:** Vatican - **Nearby attractions:** Castel Sant'Angelo - 1.2 km, Via del Corso - 1.5 km, Foro Italico - 1.9 km ## Top Vatican Hotel Reviews ![Grand Hotel Olympic](https://images.trvl-media.com/lodging/1000000/80000/72900/72827/a302c22a_y.jpg) ### Grand Hotel Olympic 10/10 Excellent "Ok." [](https://expedia.ca/Rome-Hotels-Grand-Hotel-Olympic.h72827.Hotel-Information) ![Starhotels Michelangelo](https://images.trvl-media.com/lodging/1000000/180000/176600/176543/6273dda6_y.jpg) ### Starhotels Michelangelo 10/10 Excellent "The hotel’s location is perfect if you want to be close to St. Peter’s Square. You will hear the 7:00am church bells from your room on feast days. Our queen-size bed did not feel too cramped in the room. The bathroom was a decent size with a full tub/shower. Our stay included breakfast, which included the same fare every day we were there - eggs, bacon, sausage, rice, vegetables, pastries, juices, fruit, coffee, toasts with jam, assorted cheeses and sliced meats. The dining room is ample. Service was courteous and proficiently in English. You are given the opportunity to tip at the end of your stay on your credit card. Altogether, it was a comfortable and convenient stay, worth the little more we spent on our stay. " [](https://expedia.ca/Rome-Hotels-Starhotels-Michelangelo.h176543.Hotel-Information) ![Hotel Dei Mellini](https://images.trvl-media.com/lodging/1000000/70000/63400/63399/db6d1bc9_y.jpg) ### Hotel Dei Mellini 10/10 Excellent "Delightful return to the hotel - very friendly and helpful staff. Excellent breakfast selection." [](https://expedia.ca/Rome-Hotels-Hotel-Dei-Mellini.h63399.Hotel-Information) ![Hotel Isa](https://images.trvl-media.com/lodging/1000000/860000/856900/856829/abfd2e6c_y.jpg) ### Hotel Isa 10/10 Excellent "We loved our 3-night stay at Hotel Isa. The location made everything convenient. The staff was helpful and friendly and breakfast was always wonderful. " [](https://expedia.ca/Rome-Hotels-Hotel-Isa.h856829.Hotel-Information) ![Trianon Borgo Pio](https://images.trvl-media.com/lodging/2000000/1450000/1443400/1443366/c122b911_y.jpg) ### Trianon Borgo Pio 10/10 Excellent "Nice place" [](https://expedia.ca/Rome-Hotels-Trianon-Borgo-Pio.h1443366.Hotel-Information) ![San Pietro Boutique Rooms](https://images.trvl-media.com/lodging/9000000/8380000/8378800/8378737/74470e4b_y.jpg) ### San Pietro Boutique Rooms 10/10 Excellent "Perfect location in Rome. The staff prepared everything for our arrival after their regular checkin time and we had no issues at all. They were extremely friendly and helpful. Our room was to the street, but very quiet and we enjoyed every second of our stay. " [](https://expedia.ca/Rome-Hotels-San-Pietro-Boutique-Rooms.h8378737.Hotel-Information) ![Hotel Adriatic](https://images.trvl-media.com/lodging/2000000/1620000/1615700/1615698/c74343a3_y.jpg) ### Hotel Adriatic 10/10 Excellent "Clean room and very friendly staff! Views from the room balcony and hotel terrace are wonderful! " [](https://expedia.ca/Rome-Hotels-Hotel-Adriatic.h1615698.Hotel-Information) ![Tmark Hotel Vaticano](https://images.trvl-media.com/lodging/3000000/2500000/2492800/2492730/5574ebbb_y.jpg) ### Tmark Hotel Vaticano 10/10 Excellent "Room was great and the staff was great!" [](https://expedia.ca/Rome-Hotels-Tmark-Hotel-Vaticano.h2492730.Hotel-Information) ![Hotel Diplomatic](https://images.trvl-media.com/lodging/1000000/10000/6700/6603/bb6a8be2_y.jpg) ### Hotel Diplomatic 10/10 Excellent "This hotel is in quite the perfect location! We loved how convenient it was, and made our trip so much better. The room was cute and clean. We loved the staff, specially Gianluca. He was so friendly, kind and informative. We had such a great experience, thank you so much!! " [](https://expedia.ca/Rome-Hotels-Hotel-Diplomatic.h6603.Hotel-Information) ## Frequently asked questions ### Are you searching for a great accommodation for your luxury holiday in Vatican? ### What's the best luxury hotel in Vatican? ### What's there to see and do in Vatican? ### How can I get around Vatican? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [4 Star Hotels in Prati ](https://www.expedia.ca/4Star-Prati-Rome-Hotels.s40-n6004847-0.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Rome City Centre ](https://www.expedia.ca/4Star-Rome-City-Centre-Rome-Hotels.s40-n553248633938945217-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Rome ](https://www.expedia.ca/5Star-Rome-Hotels.s50-0-d179899.Travel-Guide-Filter-Hotels) - [Hotels near AURA Shopping Mall ](https://www.expedia.ca/AURA-Shopping-Mall-Hotels.0-l553248635810270065-0.Travel-Guide-Filter-Hotels) - [Aurelio Hotels ](https://www.expedia.ca/Aurelio-Rome-Hotels.0-n6133309-0.Travel-Guide-Filter-Hotels) - 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