Title: Book The Best Hotels in Sedgewickville, MO for 2025 from CA $87 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Sedgewickville](https://expedia.ca/Sedgewickville-Vacation-Rentals.d3000349537.Travel-Guide-VacationRentals)[Sedgewickville Car Rentals](https://expedia.ca/Car-Rentals-In-Sedgewickville.d3000349537.Car-Rental-Guide)[Sedgewickville Vacation Packages](https://expedia.ca/Sedgewickville.d3000349537.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Sedgewickville, MO from CA $87 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Sedgewickville Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Sedgewickville%2C+Missouri%2C+United+States+of+America®ionId=3000349537&latLong=37.516166%2C-89.907049&adults=2&startDate=2025-10-08&d1=2025-10-08&endDate=2025-10-10&d2=2025-10-10&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Sedgewickville%2C+Missouri%2C+United+States+of+America®ionId=3000349537&latLong=37.516166%2C-89.907049&adults=2&startDate=2025-10-08&d1=2025-10-08&endDate=2025-10-10&d2=2025-10-10&amenities=POOL) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Sedgewickville%2C+Missouri%2C+United+States+of+America®ionId=3000349537&latLong=37.516166%2C-89.907049&adults=2&startDate=2025-10-08&d1=2025-10-08&endDate=2025-10-10&d2=2025-10-10&amenities=PETS) ## Check prices for these dates Tonight [Sep 24 - Sep 25](https://www.expedia.ca/Hotel-Search?regionId=3000349537&startDate=2025-09-24&endDate=2025-09-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 25 - Sep 26](https://www.expedia.ca/Hotel-Search?regionId=3000349537&startDate=2025-09-25&endDate=2025-09-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=3000349537&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=3000349537&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 77 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ## Our top choices for Sedgewickville hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/66c21f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO Jackson 9.6/10 Exceptional (1016) "Was a clean room, nice staff, good parking " CA $125 CA $132 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8571b84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars)](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Jackson 8.8/10 Excellent (623) "Excellent place to stay. Breakfast was good and staff was friendly. " CA $116 CA $126 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Deluxe Double Room](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/fc288d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/5f50a8a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/145de6a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/c0aef459.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EC Reed's Mercantile and Hotel Marble Hill 9.6/10 Exceptional (78) "Quiet small town vibe, great food and service! Definitely recommend " CA $145 CA $158 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Marble-Hill-Hotels-EC-Reeds-Mercantile-And-Hotel.h74660768.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/668f3d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/c6e7fccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Room amenity](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/d42a6e3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Perryville by IHG Perryville 9.4/10 Exceptional (508) "Have stayed here the past 3 years during the Laid Back on I-55 Truck Show! Great place to stay! The breakfast is fantastic!! The staff does not disappoint!! " CA $118 CA $135 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/1aa84b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/6f6795dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Bathroom](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/324e501c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Jackson 7.6/10 Good (414) "It was easy and quiet and an easy check in " CA $80 CA $87 total includes taxes & fees Oct 3 - Oct 4 [](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/a758bb0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/eec0e02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/bb7f277a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Jackson-Cape Girardeau Jackson 8.2/10 Very good (734) "Great area, fast check in, quiet, very spacious" CA $124 CA $134 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/9a57fa49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/e034ecf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/dc836bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cape Girardeau 7.2/10 Good (643) "nice stay" CA $80 CA $90 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/504b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible)](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/4e8bbceb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/7f26b79f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Perryville Perryville 8.4/10 Very good (912) " Love the stay and staff was great " CA $100 CA $115 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/987f0635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/5f391186.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/1e17c979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/765df2ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Madison Inn Lodge Fredericktown 7.6/10 Good (291) "Friendly staff, and pricing, accommodating to our pets" CA $121 CA $132 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Farmington-Hotels-Madison-Inn-Lodge.h59960.Hotel-Information) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/633eb669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/5aa6a52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/627d4131.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau Cape Girardeau 9.6/10 Exceptional (65) "Great overall stay" CA $140 CA $159 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/bf2aa006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/26f852d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/6b56391d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/12e65c55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Perryville I-55 Perryville 6.6/10 (118) "Right town, close to enough. " CA $96 CA $109 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/f6ab26a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/0ac21fcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/e7849830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/8b8e9c4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Perryville Perryville 6.8/10 (411) "Was a nice place." CA $100 CA $115 total includes taxes & fees Sep 27 - Sep 28 [](https://www.expedia.ca/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-09&endDate=2025-10-10®ionId=3000349537&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSedgewickville-Hotels.d3000349537.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSedgewickville-Hotels.d3000349537.Travel-Guide-Hotels) ## More cheap stays in Sedgewickville ![Holiday Inn Express & Suites Perryville by IHG](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Perryville by IHG 2020 Jefferson St, Perryville, MO CA $118 CA $135 total Oct 12 - Oct 13 includes taxes & fees 9.2/10 Wonderful! (507 reviews) [](https://expedia.ca/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Super 8 by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Perryville 1119 Vincent Dr, Perryville, MO CA $100 CA $115 total Oct 1 - Oct 2 includes taxes & fees 8.4/10 Very Good! (911 reviews) [](https://expedia.ca/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Quality Inn](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn 2011 North Kingshighway, Cape Girardeau, MO CA $80 CA $90 total Oct 1 - Oct 2 includes taxes & fees 7/10 Good! (642 reviews) [](https://expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Madison Inn Lodge](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/987f0635_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Madison Inn Lodge 730 Plaza Drive, Fredericktown, MO CA $121 CA $132 total Oct 1 - Oct 2 includes taxes & fees 7.4/10 Good! (291 reviews) [](https://expedia.ca/Farmington-Hotels-Madison-Inn-Lodge.h59960.Hotel-Information) ![Town House Inn](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Town House Inn 517 E Jackson Blvd, Jackson, MO CA $80 CA $87 total Oct 3 - Oct 4 includes taxes & fees 7.6/10 Good! (413 reviews) [](https://expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Tru By Hilton Cape Girardeau](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Cape Girardeau 2520 Veterans Memorial Dr, Cape Girardeau, MO CA $140 CA $159 total Sep 30 - Oct 1 includes taxes & fees 9.4/10 Exceptional! (62 reviews) [](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ## Hotels in Sedgewickville with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/40000000/39930000/39926100/39926011/1b66adae_w.jpg) 4 Star Hotels 1 properties [](https://expedia.ca/4Star-Sedgewickville-Hotels.s40-0-d3000349537.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_w.jpg) 3 Star Hotels 10 properties [](https://expedia.ca/3Star-Sedgewickville-Hotels.s30-0-d3000349537.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185_w.jpg) 2 Star Hotels 14 properties [](https://expedia.ca/2Star-Sedgewickville-Hotels.s20-0-d3000349537.Travel-Guide-Filter-Hotels) ## Recent reviews of Sedgewickville hotels ![EC Reed's Mercantile and Hotel](//images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/fc288d3b_y.jpg) ### EC Reed's Mercantile and Hotel 5/5 Excellent "Quiet small town vibe, great food and service! Definitely recommend " A verified traveller stayed at EC Reed's Mercantile and Hotel Posted 3 days ago [](https://expedia.ca/Marble-Hill-Hotels-EC-Reeds-Mercantile-And-Hotel.h74660768.Hotel-Information) ![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 5/5 Excellent "Brand new hotel and it’s not even shown on Google maps. Great condition and service!" A verified traveller stayed at Tru By Hilton Cape Girardeau Posted 3 days ago [](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Holiday Inn Express & Suites Perryville by IHG](//images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185_y.jpg) ### Holiday Inn Express & Suites Perryville by IHG 5/5 Excellent Excellent "Just as pictured. Excellent facility. " A verified traveller stayed at Holiday Inn Express & Suites Perryville by IHG Posted 3 days ago [](https://expedia.ca/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![The Twisted Sassafras Treehouse ](//images.trvl-media.com/lodging/96000000/95880000/95879200/95879160/55527a20_y.jpg) ### The Twisted Sassafras Treehouse 5/5 Excellent "Amazing space. So nice being up in the trees. Had an amazing, relaxing time!!!" A verified traveller stayed at The Twisted Sassafras Treehouse Posted 4 days ago [](https://expedia.ca/Cape-Girardeau-Hotels-The-Twisted-Sassafras-Treehouse.h95879160.Hotel-Information) ![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 5/5 Excellent Great hotel at a great location for a great price. "Drury Inn & Suites in Jackson Mo is always a great place to stay. We stay here every year for a local volleyball tournament and they always take care of us." A verified traveller stayed at Drury Inn & Suites Jackson MO Posted 6 days ago [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](//images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 5/5 Excellent "Everything was good i would recommend this place to people" A verified traveller stayed at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Posted 7 days ago [](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Town House Inn](//images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a_y.jpg) ### Town House Inn 5/5 Excellent "It was easy and quiet and an easy check in " A verified traveller stayed at Town House Inn Posted 8 days ago [](https://expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Beautiful Modern Loft In Wine Country!](//images.trvl-media.com/lodging/24000000/23140000/23139500/23139432/86d734a8_y.jpg) ### Beautiful Modern Loft In Wine Country! 5/5 Excellent "Well designed and decorated loft room. Comfortable and clean. Great view from the window seat. We saw turkeys in the field and turtles in the pond. Close to wineries and nature trails. Lived it!" A verified traveller stayed at Beautiful Modern Loft In Wine Country! Posted 8 days ago [](https://expedia.ca/Ste-Genevieve-Hotels-Beautiful-Modern-Loft-In-Wine-Country.h23139432.Hotel-Information) ![Quality Inn](//images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg) ### Quality Inn 5/5 Excellent "nice stay" A verified traveller stayed at Quality Inn Posted 9 days ago [](https://expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - More ways to book - [Advance Hotels](https://www.expedia.ca/Advance-Hotels.d553248634983475122.Travel-Guide-Hotels) - [Arcadia Hotels](https://www.expedia.ca/Arcadia-Hotels.d6346857.Travel-Guide-Hotels) - [Belgique Hotels](https://www.expedia.ca/Belgique-Hotels.d553248635975859150.Travel-Guide-Hotels) - [Benton Hotels](https://www.expedia.ca/Benton-Hotels.d553248634983369680.Travel-Guide-Hotels) - [Bloomsdale Hotels](https://www.expedia.ca/Bloomsdale-Hotels.d3000444549.Travel-Guide-Hotels) - [Cabin Rentals in Brazeau Township](https://www.expedia.ca/Brazeau-Township-Cabins.d553248635976430617-aaCabins.Travel-Guide-Accommodation) - 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