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Check prices for these dates

Next weekend
Aug 29 - Aug 31
In two weeks
Sep 5 - Sep 7
In one month
Sep 19 - Sep 21
In two months
Oct 17 - Oct 19

Browse Select Puxico Vacation Homes

Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
2 bedrooms, iron/ironing board, free WiFi, bed sheets

Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

8.0 out of 10, Very good, (4)
"The property was super clean. Owner was available within minutes. "
The price is CA $137
CA $349 total
includes taxes & fees
Aug 24 - Aug 25
Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Private lake, beach & hot tub, romantic getaway or family vaca
Property grounds

Private lake, beach & hot tub, romantic getaway or family vaca

9.8 out of 10, Exceptional, (30)
"We had a funeral in Poplar Bluff and needed a place to stay. This worked well for our family for the few days we stayed. "
Private lake, beach & hot tub, romantic getaway or family vaca
Lake Wappapello 2 Bedroom Home 1/8 mile to beach and boat ramp
Living area

Lake Wappapello 2 Bedroom Home 1/8 mile to beach and boat ramp

9.4 out of 10, Exceptional, (3)
"Our stay was awesome. House was very clean and adorable! "
Lake Wappapello 2 Bedroom Home 1/8 mile to beach and boat ramp
40-Acre Poplar Bluff Nature Lovers Paradise!
Interior

40-Acre Poplar Bluff Nature Lovers Paradise!

9.4 out of 10, Exceptional, (29)
"Lovely place in the country but close to town. Lots of room. "
40-Acre Poplar Bluff Nature Lovers Paradise!
Camp Stonebass-Lake House-Hottub
Interior

Camp Stonebass-Lake House-Hottub

10.0 out of 10, Exceptional, (2)
"Loved the house! It was exactly as described. Had a great family getaway in such a peaceful and serene setting. Loved the seclusion! Would definitely stay here again!"
Camp Stonebass-Lake House-Hottub
'The Lakehouse' Lovely Wappapello Country Home!
Cookware/dishes/utensils

'The Lakehouse' Lovely Wappapello Country Home!

9.8 out of 10, Exceptional, (17)
"Everything was great and clean"
'The Lakehouse' Lovely Wappapello Country Home!
Spacious & Secluded Shook Home w/ Private Hot Tub!
Interior

Spacious & Secluded Shook Home w/ Private Hot Tub!

9.4 out of 10, Exceptional, (3)
"Very comfortable beds and pillows and the cookies the host left were delicious "
Spacious & Secluded Shook Home w/ Private Hot Tub!
Home Sweet Home, Spacious Sunroom & Fun Deck!
Outdoor dining

Home Sweet Home, Spacious Sunroom & Fun Deck!

10.0 out of 10, Exceptional, (63)
"Not only is the house easy to get to, it has a spacious sun room and living room. It makes it easy to visit with family and friends. Have stayed twice and will return."
Home Sweet Home, Spacious Sunroom & Fun Deck!
Cozy 3-bedroom in Wappapello with AC, WiFi and close to the Lake.
Fridge, microwave, oven, stovetop

Cozy 3-bedroom in Wappapello with AC, WiFi and close to the Lake.

10.0 out of 10, Exceptional, (6)
"A wonderful time with family on a beautiful property inside and out. Everything we needed was provided and great attention to detail. We will definitely rent again"
Cozy 3-bedroom in Wappapello with AC, WiFi and close to the Lake.
Historic home in the heart of Poplar Bluff
Interior

Historic home in the heart of Poplar Bluff

9.6 out of 10, Exceptional, (10)
"Loved all the original details left on this property after the remodel, if you're into historic homes this is the place! "
Historic home in the heart of Poplar Bluff
Charming 3-bedroom house in delightful Advance with AC, WiFi
Exterior detail

Charming 3-bedroom house in delightful Advance with AC, WiFi

10.0 out of 10, Exceptional, (4)
"Lovely, clean home. Close to family for visit."
Charming 3-bedroom house in delightful Advance with AC, WiFi
Villa 5 · Poplar Bluff 2BR/1.5 Bath House (2022 Renovation)
Fridge, microwave, oven, stovetop

Villa 5 · Poplar Bluff 2BR/1.5 Bath House (2022 Renovation)

Villa 5 · Poplar Bluff 2BR/1.5 Bath House (2022 Renovation)
Shop House located 8 miles from Otter Slough Conservation Area
Interior

Shop House located 8 miles from Otter Slough Conservation Area

10.0 out of 10, Exceptional, (1)
"Great place to stay! Was very nice and private while still being just minutes from anything in town."
The price is CA $373
CA $532 total
includes taxes & fees
Aug 20 - Aug 21
Shop House located 8 miles from Otter Slough Conservation Area
Leopold missouri
Property grounds

Leopold missouri

Leopold missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Puxico Hotel Reviews

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel

10/10 Excellent
"This hotel has a lot of character and was so cozy. The owners have done a wonderful job creating a lovely, super easy hotel experience. The diner and mercantile were very cool. Everything felt very clean and welcoming. "
Melisa 1-night trip
Posted 1 day ago
EC Reed's Mercantile and Hotel